HDAC6 inhibition prevents TNF-α-induced caspase 3 activation in lung endothelial cell and maintains cell-cell junctions

Oncotarget

Volumn 7, Issue 34, 2016, Pages 54714-54722

  Yu, Jinyan ^a,b   Ma, Mengshi ^a,b   Ma, Zhongsen ^a   Fu, Jian ^b  

^a THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Barrier function; Caspase; Endothelial; HDAC6; Inflammation

Indexed keywords

CASPASE 3; CAY 10603; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE INHIBITOR; SMALL INTERFERING RNA; TUBASTATIN A; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; HDAC6 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL JUNCTION; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; ENDOTOXEMIA; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; LUNG EDEMA; LUNG ENDOTHELIUM; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; TIGHT JUNCTION; ANIMAL; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; GENETICS; LUNG; METABOLISM; RNA INTERFERENCE; VASCULARIZATION;

ANIMALS; CASPASE 3; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTOXEMIA; ENZYME ACTIVATION; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE INHIBITORS; HUMANS; INTERCELLULAR JUNCTIONS; LUNG; MALE; MICE, INBRED C57BL; PULMONARY EDEMA; RNA INTERFERENCE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84983568852     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.10591     Document Type: Article

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