Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration

Science Translational Medicine

Volumn 8, Issue 352, 2016, Pages

  Fan, Fuqin ^a   He, Zhixiang ^a   Kong, Lu Lu ^b   Chen, Qinghua ^a   Yuan, Quan ^a   Zhang, Shihao ^a   Ye, Jinjin ^a   Liu, Hao ^a   Sun, Xiufeng ^a   Geng, Jing ^a   Yuan, Lunzhi ^a   Hong, Lixin ^a   Xiao, Chen ^a   Zhang, Weiji ^a   Sun, Xihuan ^a   Li, Yunzhan ^a   Wang, Ping ^a   Huang, Lihong ^a   Wu, Xinrui ^a   Ji, Zhiliang ^a   Wu, Qiao ^a   Xia, Ning Shao ^a   Gray, Nathanael S ^c   Chen, Lanfen ^a   Yun, Cai Hong ^b   Deng, Xianming ^a   Zhou, Dawang ^a   more..

^a XIAMEN UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALBUMIN; DOCUSATE SODIUM; MST1 KINASE; MST2 KINASE; PARACETAMOL; PROTEIN KINASE YES; PROTEIN SERINE THREONINE KINASE; PROTEIN SERINE THREONINE KINASE INHIBITOR; UNCLASSIFIED DRUG; XMU MP 1; MACROPHAGE STIMULATING PROTEIN; MST2 PROTEIN, MOUSE; ONCOPROTEIN; PROTEIN KINASE INHIBITOR; SCATTER FACTOR; STK3 PROTEIN, HUMAN; STK4 PROTEIN, HUMAN; STK4 PROTEIN, MOUSE; SULFONAMIDE; XMU-MP-1;

ALBUMIN BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL GROWTH; CHRONIC LIVER INJURY; COLITIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG BIOAVAILABILITY; DRUG DETERMINATION; DRUG EFFECT; DRUG HALF LIFE; DRUG IDENTIFICATION; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; DRUG TOLERABILITY; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER INJURY; LIVER PROTECTION; LIVER REGENERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; PROTEIN TRANSPORT; RAT; STRUCTURE ACTIVITY RELATION; TISSUE REPAIR; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL LINE; CELL PROLIFERATION; CHEMICALLY INDUCED; CHEMISTRY; CRYSTALLIZATION; CYTOLOGY; DRUG EFFECTS; HIGH THROUGHPUT SCREENING; LUNG INJURY; MOLECULAR MODEL; REGENERATION; REGENERATIVE MEDICINE; SIGNAL TRANSDUCTION; TOXIC HEPATITIS; TRANSLATIONAL RESEARCH; TRANSPLANTATION;

ACETAMINOPHEN; ANIMALS; CELL LINE; CELL PROLIFERATION; CELLS, CULTURED; CHEMICAL AND DRUG INDUCED LIVER INJURY; COLITIS; CRYSTALLIZATION; HEPATOCYTE GROWTH FACTOR; HEPATOCYTES; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LUNG INJURY; MICE; MODELS, MOLECULAR; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; REGENERATION; REGENERATIVE MEDICINE; SIGNAL TRANSDUCTION; SULFONAMIDES; TRANSLATIONAL MEDICAL RESEARCH;

EID: 84983518011     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aaf2304     Document Type: Article

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