Neuregulin stimulation of cardiomyocyte regeneration in mice and human myocardium reveals a therapeutic window

Science Translational Medicine

Volumn 7, Issue 281, 2015, Pages

  Polizzotti, Brian D ^a,b   Ganapathy, Balakrishnan ^a,c   Walsh, Stuart ^a,b,j   Choudhury, Sangita ^a,b   Ammanamanchi, Niyatie ^a,c   Bennett, David G ^d,k   Dos Remedios, Cristobal G ^e   Haubner, Bernhard J ^f   Penninger, Josef M ^f   Kühn, Bernhard ^a,b,c,g,h,i  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^e UNIVERSITY OF SYDNEY   (Australia)

^f INSTITUTE OF MOLECULAR BIOTECHNOLOGY   (Austria)

^g HARVARD STEM CELL INSTITUTE   (United States)

^h Harvard University   (United States)

ⁱ MCGOWAN INSTITUTE FOR REGENERATIVE MEDICINE   (United States)

^j BAYER PHARMA AG   (Germany)

^k PAREXEL INTERNATIONAL   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 4; NEU DIFFERENTIATION FACTOR; ERBB4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CELL CYCLE; CELL PROLIFERATION; CELL PROTECTION; CELL REGENERATION; CELL STIMULATION; COLD INJURY; CONTROLLED STUDY; EARLY INTERVENTION; FETUS; GENE CONTROL; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; MYOCARDIAL DISEASE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGENERATIVE MEDICINE; SCAR FORMATION; TIME TO TREATMENT; TISSUE REGENERATION; ANIMAL; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CARDIOVASCULAR DISEASES; CELL DEATH; CHILD; COLD; DRUG EFFECTS; GENE EXPRESSION REGULATION; INFANT; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; REGENERATION; SCAR;

ANIMALS; ANIMALS, NEWBORN; CARDIOVASCULAR DISEASES; CELL CYCLE; CELL DEATH; CELL PROLIFERATION; CHILD; CICATRIX; COLD TEMPERATURE; GENE EXPRESSION REGULATION; HUMANS; INFANT; MICE; MYOCARDIUM; MYOCYTES, CARDIAC; NEUREGULINS; RECEPTOR, ERBB-4; REGENERATION;

EID: 84926443383     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aaa5171     Document Type: Article

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