MicroRNA-21 Lowers Blood Pressure in Spontaneous Hypertensive Rats by Upregulating Mitochondrial Translation

Circulation

Volumn 134, Issue 10, 2016, Pages 734-751

  Li, Huaping ^a   Zhang, Xiaorong ^b   Wang, Feng ^a   Zhou, Ling ^a   Yin, Zhongwei ^a   Fan, Jiahui ^a   Nie, Xiang ^a   Wang, Peihua ^a   Fu, Xiang Dong ^b,c   Chen, Chen ^a   Wang, Dao Wen ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b INSTITUTE OF BIOPHYSICS   (China)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

cytochrome b; MIR 21 microRNA, human; mitochondria; reactive oxygen species

Indexed keywords

ARGONAUTE 2 PROTEIN; CELL NUCLEUS DNA; CYTOCHROME B; MICRORNA; MICRORNA 21; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; SUPEROXIDE DISMUTASE; MIRN21 MICRORNA, RAT;

ADENO ASSOCIATED VIRUS 9; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; CARDIOMYOPATHY; CONTROLLED STUDY; COPY NUMBER VARIATION; CYTOPLASM; DOWN REGULATION; HEART VENTRICLE HYPERTROPHY; HYPERTENSION; HYPERTROPHY; IMMUNOPRECIPITATION; MITOCHONDRIAL GENOME; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA TRANSLATION; TRANSLATION REGULATION; UPREGULATION; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING; ANIMAL; DRUG EFFECTS; GENETICS; MALE; METABOLISM; PHYSIOLOGY; SPONTANEOUSLY HYPERTENSIVE RAT; TRANSCRIPTION INITIATION; WISTAR RAT;

ANIMALS; BLOOD PRESSURE; HYPERTENSION; MALE; MICRORNAS; MITOCHONDRIA; RATS; RATS, INBRED SHR; RATS, WISTAR; REACTIVE OXYGEN SPECIES; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 84983372255     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.116.023926     Document Type: Article

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