Alterations of mitochondrial enzymes contribute to cardiac hypertrophy before hypertension development in spontaneously hypertensive rats

Journal of Proteome Research

Volumn 8, Issue 5, 2009, Pages 2463-2475

  Meng, Chao ^a   Jin, Xian ^a   Xia, Li ^b   Shen, Shao Ming ^c   Wang, Xiao Ling ^b   Cai, Jun ^d   Chen, Guo Qiang ^b,c   Wang, Li Shun ^b   Fang, Ning Yuan ^a,e  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

^d SHANGHAI UNIVERSITY OF MEDICINE AND HEALTH SCIENCES   (China)

^e NONE   (China)

Author keywords

Cardiac hypertrophy; Hypertension; Mitochondrion; Proteomics; Spontaneously hypertensive rats

Indexed keywords

CELL ENZYME; HADHA ENZYME; MITOCHONDRIAL ENZYME; NADH DEHYDROGENASE 1 ALPHA SUBCOMPLEX 10S; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MEASUREMENT; CONTROLLED STUDY; DOWN REGULATION; GENE MUTATION; HEART MITOCHONDRION; HEART VENTRICLE HYPERTROPHY; HISTOPATHOLOGY; HYPERTENSION; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; TANDEM MASS SPECTROMETRY; TWO DIMENSIONAL GEL ELECTROPHORESIS; UPREGULATION;

3-HYDROXYACYL COA DEHYDROGENASES; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CARDIOMEGALY; DNA MUTATIONAL ANALYSIS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYPERTENSION; MALE; MITOCHONDRIA, HEART; MITOCHONDRIAL PROTEINS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MYOCARDIUM; NADH DEHYDROGENASE; POINT MUTATION; PROTEOMICS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TIME FACTORS;

RATTUS;

EID: 66749100634     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr801059u     Document Type: Article

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