Wnt11 gene therapy with adeno-associated virus 9 improves the survival of mice with myocarditis induced by coxsackievirus B3 through the suppression of the inflammatory reaction

Journal of Molecular and Cellular Cardiology

Volumn 84, Issue , 2015, Pages 45-51

  Aoyama, Yutaka ^a   Kobayashi, Koichi ^a   Morishita, Yoshihiro ^a   Maeda, Kengo ^a   Murohara, Toyoaki ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Adeno associated virus 9; Inflammation; Viral myocarditis; Wnt11

Indexed keywords

BETA GALACTOSIDASE; MESSENGER RNA; WNT11 PROTEIN; AUTACOID; CYTOKINE; WNT PROTEIN; WNT11 PROTEIN, MOUSE;

ADENO ASSOCIATED VIRUS 9; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR EFFECT; CELL INFILTRATION; CONTROLLED STUDY; COXSACKIE VIRUS B3; DRUG EFFECT; GENE EXPRESSION; HISTOPATHOLOGY; INFLAMMATION; INFLAMMATORY CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SURVIVAL TIME; VIRAL GENE THERAPY; VIRUS MYOCARDITIS; VIRUS RECOMBINANT; ANIMAL; ANTIBODY SPECIFICITY; BAGG ALBINO MOUSE; CHLOROCEBUS AETHIOPS; COXSACKIEVIRUS INFECTIONS; DEPENDOPARVOVIRUS; ENTEROVIRUS; GENE THERAPY; GENETICS; HEART MUSCLE; MACROPHAGE; METABOLISM; MYOCARDITIS; NECROSIS; NEUTROPHIL; PATHOLOGY; PHYSIOLOGY; SURVIVAL; T LYMPHOCYTE; VERO CELL LINE; VIROLOGY;

ADENO-ASSOCIATED VIRUS 9; ANIMALIA; COXSACKIEVIRUS; MUS;

ANIMALS; CERCOPITHECUS AETHIOPS; COXSACKIEVIRUS INFECTIONS; CYTOKINES; DEPENDOVIRUS; ENTEROVIRUS; GENE EXPRESSION; GENETIC THERAPY; INFLAMMATION; INFLAMMATION MEDIATORS; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MYOCARDITIS; MYOCARDIUM; NECROSIS; NEUTROPHILS; ORGAN SPECIFICITY; SURVIVAL ANALYSIS; T-LYMPHOCYTES; VERO CELLS; WNT PROTEINS;

EID: 84928159191     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2015.04.009     Document Type: Article

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