-
1
-
-
68249087424
-
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
-
Ishihara, N. et al. Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice. Nature cell biology 11, 958-966, doi: 10.1038/ncb1907 (2009).
-
(2009)
Nature Cell Biology
, vol.11
, pp. 958-966
-
-
Ishihara, N.1
-
2
-
-
0037593949
-
Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity
-
Bach, D. et al. Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity. The Journal of biological chemistry 278, 17190-17197, doi: 10.1074/jbc.M212754200 (2003).
-
(2003)
The Journal of Biological Chemistry
, vol.278
, pp. 17190-17197
-
-
Bach, D.1
-
3
-
-
58149400349
-
Mutated mitofusin 2 presents with intrafamilial variability and brain mitochondrial dysfunction
-
Del Bo, R. et al. Mutated mitofusin 2 presents with intrafamilial variability and brain mitochondrial dysfunction. Neurology 71, 1959-1966, doi: 10.1212/01.wnl.0000327095.32005.a4 (2008).
-
(2008)
Neurology
, vol.71
, pp. 1959-1966
-
-
Del Bo, R.1
-
4
-
-
84868110583
-
Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons
-
Lee, S. et al. Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons. Human molecular genetics 21, 4827-4835, doi: 10.1093/hmg/dds352 (2012).
-
(2012)
Human Molecular Genetics
, vol.21
, pp. 4827-4835
-
-
Lee, S.1
-
5
-
-
84868127674
-
Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit
-
Pham, A. H., Meng, S., Chu, Q. N. and Chan, D. C. Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit. Human molecular genetics 21, 4817-4826, doi: 10.1093/hmg/dds311 (2012).
-
(2012)
Human Molecular Genetics
, vol.21
, pp. 4817-4826
-
-
Pham, A.H.1
Meng, S.2
Chu, Q.N.3
Chan, D.C.4
-
7
-
-
84907816649
-
Oxidative stress-mediated activation of extracellular signal-regulated kinase contributes to mild cognitive impairmentrelated mitochondrial dysfunction
-
Gan, X. et al. Oxidative stress-mediated activation of extracellular signal-regulated kinase contributes to mild cognitive impairmentrelated mitochondrial dysfunction. Free radical biology and medicine 75, 230-240, doi: 10.1016/j.freeradbiomed.2014.07.021 (2014).
-
(2014)
Free Radical Biology and Medicine
, vol.75
, pp. 230-240
-
-
Gan, X.1
-
8
-
-
84890247564
-
Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimers disease cybrid cell
-
Gan, X. et al. Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimers disease cybrid cell. Biochim Biophys Acta 1842, 220-231, doi: 10.1016/j.bbadis.2013.11.009 (2014).
-
(2014)
Biochim Biophys Acta
, vol.1842
, pp. 220-231
-
-
Gan, X.1
-
9
-
-
84883489939
-
Mitochondrial regulation in pluripotent stem cells
-
Xu, X. et al. Mitochondrial regulation in pluripotent stem cells. Cell Metab. 18, 325-332, doi: 10.1016/j.cmet.2013.06.005 (2013).
-
(2013)
Cell Metab
, vol.18
, pp. 325-332
-
-
Xu, X.1
-
10
-
-
80052015415
-
Human induced pluripotent stem cells harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining human embryonic stem cell-like metabolic reprogramming
-
Prigione, A. et al. Human induced pluripotent stem cells harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining human embryonic stem cell-like metabolic reprogramming. Stem cells 29, 1338-1348, doi: 10.1002/stem.683 (2011).
-
(2011)
Stem Cells
, vol.29
, pp. 1338-1348
-
-
Prigione, A.1
-
11
-
-
84921260212
-
Pluripotent stem cell energy metabolism: An update
-
Teslaa, T. and Teitell, M. A. Pluripotent stem cell energy metabolism: an update. The EMBO journal 34, 138-153, doi: 10.15252/embj.201490446 (2015).
-
(2015)
The EMBO Journal
, vol.34
, pp. 138-153
-
-
Teslaa, T.1
Teitell, M.A.2
-
12
-
-
84939238182
-
Connecting mitochondria, metabolism, and stem cell fate
-
Wanet, A., Arnould, T., Najimi, M. and Renard, P. Connecting Mitochondria, Metabolism, and Stem Cell Fate. Stem cells and development 24, 1957-1971, doi: 10.1089/scd.2015.0117 (2015).
-
(2015)
Stem Cells and Development
, vol.24
, pp. 1957-1971
-
-
Wanet, A.1
Arnould, T.2
Najimi, M.3
Renard, P.4
-
13
-
-
79959221064
-
Energy metabolism in human pluripotent stem cells and their differentiated counterparts
-
Varum, S. et al. Energy metabolism in human pluripotent stem cells and their differentiated counterparts. PloS one 6, e20914, doi: 10.1371/journal.pone.0020914 (2011).
-
(2011)
PloS One
, vol.6
, pp. e20914
-
-
Varum, S.1
-
14
-
-
79960945131
-
Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming
-
Folmes, C. D. et al. Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming. Cell metabolism 14, 264-271, doi: 10.1016/j.cmet.2011.06.011 (2011).
-
(2011)
Cell Metabolism
, vol.14
, pp. 264-271
-
-
Folmes, C.D.1
-
15
-
-
37249083079
-
Mitochondrial DNA replication during differentiation of murine embryonic stem cells
-
Facucho-Oliveira, J. M., Alderson, J., Spikings, E. C., Egginton, S. and St John, J. C. Mitochondrial DNA replication during differentiation of murine embryonic stem cells. Journal of cell science 120, 4025-4034, doi: 10.1242/jcs.016972 (2007).
-
(2007)
Journal of Cell Science
, vol.120
, pp. 4025-4034
-
-
Facucho-Oliveira, J.M.1
Alderson, J.2
Spikings, E.C.3
Egginton, S.4
John, S.5
St John, J.C.6
-
16
-
-
83455235489
-
UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells
-
Zhang, J. et al. UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. The EMBO journal 30, 4860-4873, doi: 10.1038/emboj.2011.401 (2011).
-
(2011)
The EMBO Journal
, vol.30
, pp. 4860-4873
-
-
Zhang, J.1
-
17
-
-
84939248341
-
Differentiation of human neural stem cells into motor neurons stimulates mitochondrial biogenesis and decreases glycolytic flux
-
OBrien, L. C., Keeney, P. M. and Bennett, J. P., Jr. Differentiation of Human Neural Stem Cells into Motor Neurons Stimulates Mitochondrial Biogenesis and Decreases Glycolytic Flux. Stem cells and development, doi: 10.1089/scd.2015.0076 (2015).
-
(2015)
Stem Cells and Development
-
-
O'Brien, L.C.1
Keeney, P.M.2
Bennett, J.P.3
-
18
-
-
70349860263
-
Enhancement of human embryonic stem cell pluripotency through inhibition of the mitochondrial respiratory chain
-
Varum, S. et al. Enhancement of human embryonic stem cell pluripotency through inhibition of the mitochondrial respiratory chain. Stem cell research 3, 142-156, doi: 10.1016/j.scr.2009.07.002 (2009).
-
(2009)
Stem Cell Research
, vol.3
, pp. 142-156
-
-
Varum, S.1
-
19
-
-
2342594384
-
The mitochondrial production of reactive oxygen species in relation to aging and pathology
-
Genova, M. L. et al. The mitochondrial production of reactive oxygen species in relation to aging and pathology. Annals of the New York Academy of Sciences 1011, 86-100 (2004).
-
(2004)
Annals of the New York Academy of Sciences
, vol.1011
, pp. 86-100
-
-
Genova, M.L.1
-
20
-
-
31844439407
-
Sublethal mitochondrial stress with an attendant stoichiometric augmentation of reactive oxygen species may precipitate many of the beneficial alterations in cellular physiology produced by caloric restriction intermittent fasting exercise and dietary phytonutrients: "mitohormesis" for health and vitality
-
Tapia, P. C. Sublethal mitochondrial stress with an attendant stoichiometric augmentation of reactive oxygen species may precipitate many of the beneficial alterations in cellular physiology produced by caloric restriction, intermittent fasting, exercise and dietary phytonutrients: "Mitohormesis" for health and vitality. Medical hypotheses 66, 832-843, doi: 10.1016/j.mehy.2005.09.009 (2006).
-
(2006)
Medical Hypotheses
, vol.66
, pp. 832-843
-
-
Tapia, P.C.1
-
21
-
-
84868007565
-
Physiological roles of mitochondrial reactive oxygen species
-
Sena, L. A. and Chandel, N. S. Physiological roles of mitochondrial reactive oxygen species. Molecular cell 48, 158-167, doi: 10.1016/j. molcel.2012.09.025 (2012).
-
(2012)
Molecular Cell
, vol.48
, pp. 158-167
-
-
Sena, L.A.1
Chandel, N.S.2
-
22
-
-
84883003491
-
Oxidative stress inhibits adhesion and transendothelial migration, and induces apoptosis and senescence of induced pluripotent stem cells
-
Wu, Y. et al. Oxidative stress inhibits adhesion and transendothelial migration, and induces apoptosis and senescence of induced pluripotent stem cells. Clinical and experimental pharmacology and physiology 40, 626-634, doi: 10.1111/1440-1681.12141 (2013).
-
(2013)
Clinical and Experimental Pharmacology and Physiology
, vol.40
, pp. 626-634
-
-
Wu, Y.1
-
23
-
-
84863584524
-
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinsons disease
-
Cooper, O. et al. Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinsons disease. Science translational medicine 4, 141ra190, doi: 10.1126/scitranslmed.3003985 (2012).
-
(2012)
Science Translational Medicine
, vol.4
, pp. 141ra190
-
-
Cooper, O.1
-
24
-
-
77956199031
-
A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimers disease
-
Santos, R. X. et al. A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimers disease. Journal of Alzheimers disease: JAD 20 Suppl 2, S401-S412, doi: 10.3233/JAD-2010-100666 (2010).
-
(2010)
Journal of Alzheimers Disease: JAD
, vol.20
, pp. S401-S412
-
-
Santos, R.X.1
-
26
-
-
84867905197
-
Mitochondrial superoxide production negatively regulates neural progenitor proliferation and cerebral cortical development
-
Hou, Y. et al. Mitochondrial superoxide production negatively regulates neural progenitor proliferation and cerebral cortical development. Stem cells 30, 2535-2547, doi: 10.1002/stem.1213 (2012).
-
(2012)
Stem Cells
, vol.30
, pp. 2535-2547
-
-
Hou, Y.1
-
27
-
-
84887987260
-
Unveiling the critical role of REX1 in the regulation of human stem cell pluripotency
-
Son, M. Y., Choi, H., Han, Y. M. and Cho, Y. S. Unveiling the critical role of REX1 in the regulation of human stem cell pluripotency. Stem cells 31, 2374-2387, doi: 10.1002/stem.1509 (2013).
-
(2013)
Stem Cells
, vol.31
, pp. 2374-2387
-
-
Son, M.Y.1
Choi, H.2
Han, Y.M.3
Cho, Y.S.4
-
28
-
-
0037455575
-
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
-
Chen, H. et al. Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. The Journal of cell biology 160, 189-200, doi: 10.1083/jcb.200211046 (2003).
-
(2003)
The Journal of Cell Biology
, vol.160
, pp. 189-200
-
-
Chen, H.1
-
29
-
-
16244368805
-
Newborn neurons acquire high levels of reactive oxygen species and increased mitochondrial proteins upon differentiation from progenitors
-
Tsatmali, M., Walcott, E. C. and Crossin, K. L. Newborn neurons acquire high levels of reactive oxygen species and increased mitochondrial proteins upon differentiation from progenitors. Brain research 1040, 137-150, doi: 10.1016/j.brainres.2005.01.087 (2005).
-
(2005)
Brain Research
, vol.1040
, pp. 137-150
-
-
Tsatmali, M.1
Walcott, E.C.2
Crossin, K.L.3
-
30
-
-
84904627477
-
Dual modulation of the mitochondrial permeability transition pore and redox signaling synergistically promotes cardiomyocyte differentiation from pluripotent stem cells
-
Cho, S. W. et al. Dual modulation of the mitochondrial permeability transition pore and redox signaling synergistically promotes cardiomyocyte differentiation from pluripotent stem cells. Journal of the American Heart Association 3, e000693, doi: 10.1161/JAHA.113.000693 (2014).
-
(2014)
Journal of the American Heart Association
, vol.3
, pp. e000693
-
-
Cho, S.W.1
-
31
-
-
57349100367
-
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
-
de Brito, O. M. and Scorrano, L. Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 456, 605-610, doi: 10.1038/nature07534 (2008).
-
(2008)
Nature
, vol.456
, pp. 605-610
-
-
De Brito, O.M.1
Scorrano, L.2
-
33
-
-
84868135412
-
Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions
-
Beers, J. et al. Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions. Nature protocols 7, 2029-2040, doi: 10.1038/nprot.2012.130 (2012).
-
(2012)
Nature Protocols
, vol.7
, pp. 2029-2040
-
-
Beers, J.1
-
34
-
-
84870030633
-
Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks
-
Shi, Y., Kirwan, P. and Livesey, F. J. Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks. Nature protocols 7, 1836-1846, doi: 10.1038/nprot.2012.116 (2012).
-
(2012)
Nature Protocols
, vol.7
, pp. 1836-1846
-
-
Shi, Y.1
Kirwan, P.2
Livesey, F.J.3
-
35
-
-
84877139837
-
A novel human embryonic stem cell-derived Huntingtons disease neuronal model exhibits mutant huntingtin (mHTT) aggregates and soluble mHTT-dependent neurodegeneration
-
Lu, B. and Palacino, J. A novel human embryonic stem cell-derived Huntingtons disease neuronal model exhibits mutant huntingtin (mHTT) aggregates and soluble mHTT-dependent neurodegeneration. FASEB journal: official publication of the Federation of American Societies for Experimental Biology 27, 1820-1829, doi: 10.1096/fj.12-219220 (2013).
-
(2013)
FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
, vol.27
, pp. 1820-1829
-
-
Lu, B.1
Palacino, J.2
-
36
-
-
84940642263
-
Increased neuronal PreP activity reduces Abeta accumulation, attenuates neuroinflammation and improves mitochondrial and synaptic function in Alzheimer diseases mouse model
-
Fang, D. et al. Increased neuronal PreP activity reduces Abeta accumulation, attenuates neuroinflammation and improves mitochondrial and synaptic function in Alzheimer diseases mouse model. Human molecular genetics 24, 5198-5210, doi: 10.1093/hmg/ddv241 (2015).
-
(2015)
Human Molecular Genetics
, vol.24
, pp. 5198-5210
-
-
Fang, D.1
-
37
-
-
77649162059
-
Direct conversion of fibroblasts to functional neurons by defined factors
-
Vierbuchen, T. et al. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 463, 1035-1041, doi: 10.1038/nature08797 (2010).
-
(2010)
Nature
, vol.463
, pp. 1035-1041
-
-
Vierbuchen, T.1
-
38
-
-
53549129483
-
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimers disease
-
Du, H. et al. Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimers disease. Nature medicine 14, 1097-1105, doi: 10.1038/nm.1868 (2008).
-
(2008)
Nature Medicine
, vol.14
, pp. 1097-1105
-
-
Du, H.1
-
39
-
-
78649815388
-
Early deficits in synaptic mitochondria in an Alzheimers disease mouse model
-
Du, H. et al. Early deficits in synaptic mitochondria in an Alzheimers disease mouse model. Proceedings of the National Academy of Sciences of the United States of America 107, 18670-18675, doi: 10.1073/pnas.1006586107 (2010).
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, pp. 18670-18675
-
-
Du, H.1
-
40
-
-
84873130522
-
Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimers neurons
-
Guo, L. et al. Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimers neurons. PloS one 8, e54914, doi: 10.1371/journal.pone.0054914 (2013).
-
(2013)
PloS One
, vol.8
, pp. e54914
-
-
Guo, L.1
-
41
-
-
24144438228
-
Differentiated Alzheimers disease transmitochondrial cybrid cell lines exhibit reduced organelle movement
-
Trimmer, P. A. and Borland, M. K. Differentiated Alzheimers disease transmitochondrial cybrid cell lines exhibit reduced organelle movement. Antioxidants and redox signaling 7, 1101-1109, doi: 10.1089/ars.2005.7.1101 (2005).
-
(2005)
Antioxidants and Redox Signaling
, vol.7
, pp. 1101-1109
-
-
Trimmer, P.A.1
Borland, M.K.2
|