메뉴 건너뛰기




Volumn 1, Issue 1, 2014, Pages

FMRP regulates neurogenesis in vivo in Xenopus laevis tadpoles

Author keywords

Dendrite development; FMRP; Fragile X Syndrome; In vivo imaging; Neurogenesis; Xenopus

Indexed keywords


EID: 84983179985     PISSN: None     EISSN: 23732822     Source Type: Journal    
DOI: 10.1523/ENEURO.0055-14.2014     Document Type: Article
Times cited : (9)

References (73)
  • 1
    • 0027300283 scopus 로고
    • Nucleus basalis magnocellularis and hippocampus are the major sites of FMR-1 expression in the human fetal brain
    • Abitbol M, Menini C, Delezoide AL, Rhyner T, Vekemans M, Mallet J (1993) Nucleus basalis magnocellularis and hippocampus are the major sites of FMR-1 expression in the human fetal brain. Nat Genet 4:147–153. CrossRef Medline
    • (1993) Nat Genet , vol.4 , pp. 147-153
    • Abitbol, M.1    Menini, C.2    Delezoide, A.L.3    Rhyner, T.4    Vekemans, M.5    Mallet, J.6
  • 3
    • 82355170659 scopus 로고    scopus 로고
    • In vivo time-lapse imaging of cell proliferation and differentiation in the optic tectum of xenopus laevis tadpoles
    • Bestman JE, Lee-Osbourne J, Cline HT (2012) In vivo time-lapse imaging of cell proliferation and differentiation in the optic tectum of xenopus laevis tadpoles. J Comp Neurol 520:401–433. Cross-Ref Medline
    • (2012) J Comp Neurol , pp. 401-433
    • Bestman, J.E.1    Lee-Osbourne, J.2    Cline, H.T.3
  • 4
    • 84862637069 scopus 로고    scopus 로고
    • The pathophysiology of fragile X (And what it teaches us about synapses)
    • Bhakar AL, Dölen G, Bear MF (2012) The pathophysiology of fragile X (and what it teaches us about synapses). Annu Rev Neurosci 35:417–443. CrossRef Medline
    • (2012) Annu Rev Neurosci , vol.35 , pp. 417-443
    • Bhakar, A.L.1    Dölen, G.2    Bear, M.F.3
  • 6
    • 52949109182 scopus 로고    scopus 로고
    • Excess protein synthesis in drosophila fragile X mutants impairs long-term memory
    • Bolduc FV, Bell K, Cox H, Broadie KS, Tully T (2008) Excess protein synthesis in drosophila fragile X mutants impairs long-term memory. Nat Neurosci 11:1143–1145. CrossRef Medline
    • (2008) Nat Neurosci , vol.11 , pp. 1143-1145
    • Bolduc, F.V.1    Bell, K.2    Cox, H.3    Broadie, K.S.4    Tully, T.5
  • 7
    • 77958181092 scopus 로고    scopus 로고
    • Fragile X protein controls neural stem cell proliferation in the drosophila brain
    • Callan MA, Cabernard C, Heck J, Luois S, Doe CQ, Zarnescu DC (2010) Fragile X protein controls neural stem cell proliferation in the drosophila brain. Hum Mol Genet 19:3068–3079. CrossRef Med-line
    • (2010) Hum Mol Genet , vol.19 , pp. 3068-3079
    • Callan, M.A.1    Cabernard, C.2    Heck, J.3    Luois, S.4    Doe, C.Q.5    Zarnescu, D.C.6
  • 9
    • 84883458323 scopus 로고    scopus 로고
    • Programmed cell death is impaired in the developing brain of FMR1 mutants
    • Cheng Y, Corbin JG, Levy RJ (2013) Programmed cell death is impaired in the developing brain of FMR1 mutants. Dev Neurosci 35:347–358. CrossRef Medline
    • (2013) Dev Neurosci , vol.35 , pp. 347-358
    • Cheng, Y.1    Corbin, J.G.2    Levy, R.J.3
  • 11
    • 77953528456 scopus 로고    scopus 로고
    • Delayed stabilization of dendritic spines in fragile X mice
    • Cruz-Martín A, Crespo M, Portera-Cailliau C (2010) Delayed stabilization of dendritic spines in fragile X mice. J Neurosci 30:7793– 7803. CrossRef Medline
    • (2010) J Neurosci , vol.30 , pp. 7793-7803
    • Cruz-Martín, A.1    Crespo, M.2    Portera-Cailliau, C.3
  • 13
    • 0027176361 scopus 로고
    • The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation
    • Devys D, Lutz Y, Rouyer N, Bellocq JP, Mandel JL (1993) The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation. Nat Genet 4:335–340. CrossRef Medline
    • (1993) Nat Genet , vol.4 , pp. 335-340
    • Devys, D.1    Lutz, Y.2    Rouyer, N.3    Bellocq, J.P.4    Mandel, J.L.5
  • 15
    • 84893578436 scopus 로고    scopus 로고
    • Impaired activity-dependent neural circuit assembly and refinement in autism spectrum disorder genetic models
    • Doll CA, Broadie K (2014) Impaired activity-dependent neural circuit assembly and refinement in autism spectrum disorder genetic models. Front Cell Neurosci 8:30.[PMC] [CrossRef ][Medline]
    • (2014) Front Cell Neurosci , vol.8 , pp. 30
    • Doll, C.A.1    Broadie, K.2
  • 16
    • 70349762428 scopus 로고    scopus 로고
    • Fmr1 knockout mice show reduced anxiety and alterations in neurogenesis that are specific to the ventral dentate gyrus
    • Eadie BD, Zhang WN, Boehme F, Gil-Mohapel J, Kainer L, Simpson JM, Christie BR (2009) Fmr1 knockout mice show reduced anxiety and alterations in neurogenesis that are specific to the ventral dentate gyrus. Neurobiol Dis 36:361–373. CrossRef Medline
    • (2009) Neurobiol Dis , vol.36 , pp. 361-373
    • Eadie, B.D.1    Zhang, W.N.2    Boehme, F.3    Gil-Mohapel, J.4    Kainer, L.5    Simpson, J.M.6    Christie, B.R.7
  • 19
    • 0347155731 scopus 로고    scopus 로고
    • Somatosensory cortical barrel dendritic abnormalities in a mouse model of the fragile X mental retardation syndrome
    • Galvez R, Gopal AR, Greenough WT (2003) Somatosensory cortical barrel dendritic abnormalities in a mouse model of the fragile X mental retardation syndrome. Brain Res 971:83–89.CrossRef
    • (2003) Brain Res , vol.971 , pp. 83-89
    • Galvez, R.1    Gopal, A.R.2    Greenough, W.T.3
  • 20
    • 79960561796 scopus 로고    scopus 로고
    • Fragile X mental retardation protein is required for programmed cell death and clearance of developmentally-transient peptidergic neurons
    • Gatto CL, Broadie K (2011) Fragile X mental retardation protein is required for programmed cell death and clearance of developmentally-transient peptidergic neurons. Dev Biol 356:291– 307. CrossRef Medline
    • (2011) Dev Biol , vol.356 , pp. 291-307
    • Gatto, C.L.1    Broadie, K.2
  • 21
    • 77951209999 scopus 로고    scopus 로고
    • FMR1/FXR1 and the miRNA pathway are required for eye and neural crest development
    • Gessert S, Bugner V, Tecza A, Pinker M, Kühl M (2010) FMR1/FXR1 and the miRNA pathway are required for eye and neural crest development. Dev Biol 341:222–235. CrossRef Medline
    • (2010) Dev Biol , vol.341 , pp. 222-235
    • Gessert, S.1    Bugner, V.2    Tecza, A.3    Pinker, M.4    Kühl, M.5
  • 24
    • 84862908964 scopus 로고    scopus 로고
    • Inhibition of GSK3beta improves hippocampus-dependent learning and rescues neurogenesis in a mouse model of fragile X syndrome
    • Guo W, Murthy AC, Zhang L, Johnson EB, Schaller EG, Allan AM, Zhao X (2012) Inhibition of GSK3beta improves hippocampus-dependent learning and rescues neurogenesis in a mouse model of fragile X syndrome. Hum Mol Genet 21:681–691. CrossRef Medline
    • (2012) Hum Mol Genet , vol.21 , pp. 681-691
    • Guo, W.1    Murthy, A.C.2    Zhang, L.3    Johnson, E.B.4    Schaller, E.G.5    Allan, A.M.6    Zhao, X.7
  • 25
    • 84884289158 scopus 로고    scopus 로고
    • The trouble with spines in fragile X syndrome: Density, maturity and plasticity
    • He CX, Portera-Cailliau C (2013) The trouble with spines in fragile X syndrome: density, maturity and plasticity. Neuroscience 251: 120–128. CrossRef Medline
    • (2013) Neuroscience , vol.251 , pp. 120-128
    • He, C.X.1    Portera-Cailliau, C.2
  • 26
    • 84881665478 scopus 로고    scopus 로고
    • Duplication of the Xq27.3-q28 region, including the FMR1 gene, in an X-linked hypogonadism, gyneco-mastia, intellectual disability, short stature, and obesity syndrome
    • Hickey SE, Walters-Sen L, Mosher TM, Pfau RB, Pyatt R, Snyder PJ, Sotos JF, Prior TW (2013) Duplication of the Xq27.3-q28 region, including the FMR1 gene, in an X-linked hypogonadism, gyneco-mastia, intellectual disability, short stature, and obesity syndrome. Am J Med Genet A 161A:2294–2299.CrossRef
    • (2013) Am J Med Genet A , vol.161 , pp. 2294-2299
    • Hickey, S.E.1    Walters-Sen, L.2    Mosher, T.M.3    Pfau, R.B.4    Pyatt, R.5    Snyder, P.J.6    Sotos, J.F.7    Prior, T.W.8
  • 28
    • 0025720084 scopus 로고
    • Analysis of neocortex in three males with the fragile X syndrome
    • Hinton VJ, Brown WT, Wisniewski K, Rudelli RD (1991) Analysis of neocortex in three males with the fragile X syndrome. Am J Med Genet 41:289–294. CrossRef Medline
    • (1991) Am J Med Genet , vol.41 , pp. 289-294
    • Hinton, V.J.1    Brown, W.T.2    Wisniewski, K.3    Rudelli, R.D.4
  • 29
    • 0033797832 scopus 로고    scopus 로고
    • Dendritic spine structural anomalies in fragile-X mental retardation syndrome
    • Irwin SA, Galvez R, Greenough WT (2000) Dendritic spine structural anomalies in fragile-X mental retardation syndrome. Cereb Cortex 10:1038–1044. Medline
    • (2000) Cereb Cortex , vol.10 , pp. 1038-1044
    • Irwin, S.A.1    Galvez, R.2    Greenough, W.T.3
  • 32
    • 77949835797 scopus 로고    scopus 로고
    • Astrocytes prevent abnormal neuronal development in the fragile x mouse
    • Jacobs S, Doering LC (2010) Astrocytes prevent abnormal neuronal development in the fragile x mouse. J Neurosci 30:4508–4514. CrossRef Medline
    • (2010) J Neurosci , vol.30 , pp. 4508-4514
    • Jacobs, S.1    Doering, L.C.2
  • 35
    • 23044503253 scopus 로고    scopus 로고
    • Deletion of FMR1 in purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in fragile X syndrome
    • Koekkoek SK et al (2005) Deletion of FMR1 in purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in fragile X syndrome. Neuron 47:339– 352. CrossRef Medline
    • (2005) Neuron , vol.47 , pp. 339-352
    • Koekkoek, S.K.1
  • 36
    • 33845480548 scopus 로고    scopus 로고
    • Caspase function in programmed cell death
    • Kumar S (2007) Caspase function in programmed cell death. Cell Death Differ 14:32–43. CrossRef Medline
    • (2007) Cell Death Differ , vol.14 , pp. 32-43
    • Kumar, S.1
  • 37
    • 84861345954 scopus 로고    scopus 로고
    • Impaired survival of neural progenitor cells in dentate gyrus of adult mice lacking fMRP
    • Lazarov O, Demars MP, Zhao Kda T, Ali HM, Grauzas V, Kney A, Larson J (2012) Impaired survival of neural progenitor cells in dentate gyrus of adult mice lacking fMRP. Hippocampus 22:1220– 1224. CrossRef Medline
    • (2012) Hippocampus , vol.22 , pp. 1220-1224
    • Lazarov, O.1    Demars, M.P.2    Zhao Kda, T.3    Ali, H.M.4    Grauzas, V.5    Kney, A.6    Larson, J.7
  • 38
    • 0345308602 scopus 로고    scopus 로고
    • Control of dendritic development by the drosophila fragile X-related gene involves the small GTPase Rac1
    • Lee A, Li W, Xu K, Bogert BA, Su K, Gao FB (2003) Control of dendritic development by the drosophila fragile X-related gene involves the small GTPase Rac1. Development 130:5543–5552. CrossRef Medline
    • (2003) Development , vol.130 , pp. 5543-5552
    • Lee, A.1    Li, W.2    Xu, K.3    Bogert, B.A.4    Su, K.5    Gao, F.B.6
  • 39
    • 84902593066 scopus 로고    scopus 로고
    • Concise review: Fragile X proteins in stem cell maintenance and differentiation
    • Li Y, Zhao X (2014) Concise review: fragile X proteins in stem cell maintenance and differentiation. Stem Cells 32:1724–1733. CrossRef Medline
    • (2014) Stem Cells , vol.32 , pp. 1724-1733
    • Li, Y.1    Zhao, X.2
  • 40
    • 73849141236 scopus 로고    scopus 로고
    • Gene, brain, and behavior relationships in fragile X syndrome: Evidence from neuroimaging studies
    • Lightbody AA, Reiss AL (2009) Gene, brain, and behavior relationships in fragile X syndrome: evidence from neuroimaging studies. Dev Disabil Res Rev 15:343–352. CrossRef Medline
    • (2009) Dev Disabil Res Rev , vol.15 , pp. 343-352
    • Lightbody, A.A.1    Reiss, A.L.2
  • 41
    • 29044436565 scopus 로고    scopus 로고
    • Developmental expression of xenopus fragile X mental retardation-1 gene
    • Lim JH, Luo T, Sargent TD, Fallon JR (2005) Developmental expression of xenopus fragile X mental retardation-1 gene. Int J Dev Biol 49:981–984. CrossRef Medline
    • (2005) Int J Dev Biol , vol.49 , pp. 981-984
    • Lim, J.H.1    Luo, T.2    Sargent, T.D.3    Fallon, J.R.4
  • 42
    • 84867833898 scopus 로고    scopus 로고
    • Drosophila FMRP participates in the DNA damage response by regulating G2/M cell cycle checkpoint and apoptosis
    • Liu W, Jiang F, Bi X, Zhang YQ (2012) Drosophila FMRP participates in the DNA damage response by regulating G2/M cell cycle checkpoint and apoptosis. Hum Mol Genet 21:4655–4668. CrossRef Medline
    • (2012) Hum Mol Genet , vol.21 , pp. 4655-4668
    • Liu, W.1    Jiang, F.2    Bi, X.3    Zhang, Y.Q.4
  • 44
    • 70349104269 scopus 로고    scopus 로고
    • Netrin participates in the development of retinotectal synaptic connectivity by modulating axon arborization and synapse formation in the developing brain
    • CrossRef Medline
    • Manitt C, Nikolakopoulou AM, Almario DR, Nguyen SA, Cohen-Cory S (2009) Netrin participates in the development of retinotectal synaptic connectivity by modulating axon arborization and synapse formation in the developing brain. J Neurosci 29:11065– 11077. CrossRef Medline
    • (2009) J Neurosci , vol.29 , pp. 11065-11077
    • Manitt, C.1    Nikolakopoulou, A.M.2    Almario, D.R.3    Nguyen, S.A.4    Cohen-Cory, S.5
  • 47
    • 0035879180 scopus 로고    scopus 로고
    • Abnormal development of dendritic spines in FMR1 knock-out mice
    • Nimchinsky EA, Oberlander AM, Svoboda K (2001) Abnormal development of dendritic spines in FMR1 knock-out mice. J Neurosci 21:5139–5146. Medline
    • (2001) J Neurosci , vol.21 , pp. 5139-5146
    • Nimchinsky, E.A.1    Oberlander, A.M.2    Svoboda, K.3
  • 49
    • 35048886071 scopus 로고    scopus 로고
    • Developmental expression of FMRP in the astrocyte lineage: Implications for fragile X syndrome
    • Pacey LK, Doering LC (2007) Developmental expression of FMRP in the astrocyte lineage: implications for fragile X syndrome. Glia 55:1601–1609. CrossRef Medline
    • (2007) Glia , vol.55 , pp. 1601-1609
    • Pacey, L.K.1    Doering, L.C.2
  • 51
    • 33645450007 scopus 로고    scopus 로고
    • Stabilization of axon branch dynamics by synaptic maturation
    • Ruthazer ES, Li J, Cline HT (2006) Stabilization of axon branch dynamics by synaptic maturation. J Neurosci 26:3594–3603. CrossRef Medline
    • (2006) J Neurosci , vol.26 , pp. 3594-3603
    • Ruthazer, E.S.1    Li, J.2    Cline, H.T.3
  • 52
    • 0033955447 scopus 로고    scopus 로고
    • Pathological and neuropathological findings in two males with fragile-X syndrome
    • Sabaratnam M (2000) Pathological and neuropathological findings in two males with fragile-X syndrome. J Intellect Disabil Res 44: 81–85.CrossRef
    • (2000) J Intellect Disabil Res , vol.44 , pp. 81-85
    • Sabaratnam, M.1
  • 53
    • 79251547954 scopus 로고    scopus 로고
    • FMRP regulates the transition from radial glial cells to intermediate progenitor cells during neocortical development
    • Saffary R, Xie Z (2011) FMRP regulates the transition from radial glial cells to intermediate progenitor cells during neocortical development. J Neurosci 31:1427–1439. CrossRef Medline
    • (2011) J Neurosci , vol.31 , pp. 1427-1439
    • Saffary, R.1    Xie, Z.2
  • 54
    • 84856879093 scopus 로고    scopus 로고
    • Molecular mechanisms of fragile X syndrome: A twenty-year perspective
    • Santoro MR, Bray SM, Warren ST (2012) Molecular mechanisms of fragile X syndrome: a twenty-year perspective. Annu Rev Pathol 7:219–245. CrossRef Medline
    • (2012) Annu Rev Pathol , vol.7 , pp. 219-245
    • Santoro, M.R.1    Bray, S.M.2    Warren, S.T.3
  • 56
    • 78049281858 scopus 로고    scopus 로고
    • Visual activity regulates neural progenitor cells in developing xenopus CNS through musashi1
    • Sharma P, Cline HT (2010) Visual activity regulates neural progenitor cells in developing xenopus CNS through musashi1. Neuron 68: 442–455. CrossRef Medline
    • (2010) Neuron , vol.68 , pp. 442-455
    • Sharma, P.1    Cline, H.T.2
  • 57
    • 80053948646 scopus 로고    scopus 로고
    • Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome
    • Sheridan SD, Theriault KM, Reis SA, Zhou F, Madison JM, Daheron L, Loring JF, Haggarty SJ (2011) Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome. PLoS One 6:e26203[PMC] [CrossRef ][Medline]
    • (2011) Plos One , vol.6 , pp. 26203
    • Sheridan, S.D.1    Theriault, K.M.2    Reis, S.A.3    Zhou, F.4    Madison, J.M.5    Daheron, L.6    Loring, J.F.7    Haggarty, S.J.8
  • 58
    • 0037015579 scopus 로고    scopus 로고
    • Dendrite growth increased by visual activity requires NMDA receptor and rho GT-Pases
    • Sin WC, Haas K, Ruthazer ES, Cline HT (2002) Dendrite growth increased by visual activity requires NMDA receptor and rho GT-Pases. Nature 419:475–480. CrossRef Medline
    • (2002) Nature , vol.419 , pp. 475-480
    • Sin, W.C.1    Haas, K.2    Ruthazer, E.S.3    Cline, H.T.4
  • 59
    • 84872370488 scopus 로고    scopus 로고
    • Neural differentiation of fragile X human embryonic stem cells reveals abnormal patterns of development despite successful neurogenesis
    • Telias M, Segal M, Ben-Yosef D (2013) Neural differentiation of fragile X human embryonic stem cells reveals abnormal patterns of development despite successful neurogenesis. Dev Biol 374:32–45. CrossRef Medline
    • (2013) Dev Biol , vol.374 , pp. 32-45
    • Telias, M.1    Segal, M.2    Ben-Yosef, D.3
  • 61
    • 53049096202 scopus 로고    scopus 로고
    • Modest alterations in patterns of motor neuron dendrite morphology in the Fmr1 knockout mouse model for fragile X
    • Thomas CC, Combe CL, Dyar KA, Inglis FM (2008) Modest alterations in patterns of motor neuron dendrite morphology in the Fmr1 knockout mouse model for fragile X. Int J Dev Neurosci 26:805– 811.CrossRef
    • (2008) Int J Dev Neurosci , vol.26 , pp. 805-811
    • Thomas, C.C.1    Combe, C.L.2    Dyar, K.A.3    Inglis, F.M.4
  • 63
    • 77956214743 scopus 로고    scopus 로고
    • Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells
    • Urbach A, Bar-Nur O, Daley GQ, Benvenisty N (2010) Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. Cell Stem Cell 6:407–411. CrossRef Medline
    • (2010) Cell Stem Cell , vol.6 , pp. 407-411
    • Urbach, A.1    Bar-Nur, O.2    Daley, G.Q.3    Benvenisty, N.4
  • 65
    • 84867743191 scopus 로고    scopus 로고
    • De novo microduplication of the FMR1 gene in a patient with developmental delay, epilepsy and hyperactivity
    • Vengoechea J, Parikh AS, Zhang S, Tassone F (2012) De novo microduplication of the FMR1 gene in a patient with developmental delay, epilepsy and hyperactivity. Eur J Hum Genet 20:1197– 1200. CrossRef Medline
    • (2012) Eur J Hum Genet , vol.20 , pp. 1197-1200
    • Vengoechea, J.1    Parikh, A.S.2    Zhang, S.3    Tassone, F.4
  • 68
    • 0033761489 scopus 로고    scopus 로고
    • Characterization of dFMR1, a drosophila melanogaster homolog of the fragile X mental retardation protein
    • Wan L, Dockendorff TC, Jongens TA, Dreyfuss G (2000) Characterization of dFMR1, a drosophila melanogaster homolog of the fragile X mental retardation protein. Mol Cell Biol 20:8536–8547. Medline
    • (2000) Mol Cell Biol , vol.20 , pp. 8536-8547
    • Wan, L.1    Dockendorff, T.C.2    Jongens, T.A.3    Dreyfuss, G.4
  • 69
    • 68649093278 scopus 로고    scopus 로고
    • Protein translation in synaptic plasticity: MGluR-LTD, fragile X
    • Waung MW, Huber KM (2009) Protein translation in synaptic plasticity: mGluR-LTD, fragile X. Curr Opin Neurobiol 19:319–326. CrossRef Medline
    • (2009) Curr Opin Neurobiol , vol.19 , pp. 319-326
    • Waung, M.W.1    Huber, K.M.2
  • 71
    • 0036626521 scopus 로고    scopus 로고
    • Timing of the absence of FMR1 expression in full mutation chorionic villi
    • Willemsen R, Bontekoe CJ, Severijnen LA, Oostra BA (2002) Timing of the absence of FMR1 expression in full mutation chorionic villi. Hum Genet 110:601–605. CrossRef Medline
    • (2002) Hum Genet , vol.110 , pp. 601-605
    • Willemsen, R.1    Bontekoe, C.J.2    Severijnen, L.A.3    Oostra, B.A.4
  • 72
    • 84907838387 scopus 로고    scopus 로고
    • A feedforward mechanism involving drosophila fragile X mental retardation protein triggers a replication stress-induced DNA damage response
    • Zhang W, Cheng Y, Li Y, Chen Z, Jin P, Chen D (2014) A feedforward mechanism involving drosophila fragile X mental retardation protein triggers a replication stress-induced DNA damage response. Hum Mol Genet 23:5188–5196. CrossRef Medline
    • (2014) Hum Mol Genet , vol.23 , pp. 5188-5196
    • Zhang, W.1    Cheng, Y.2    Li, Y.3    Chen, Z.4    Jin, P.5    Chen, D.6
  • 73
    • 84862659562 scopus 로고    scopus 로고
    • Synaptic dysfunction in neurodevelop-mental disorders associated with autism and intellectual disabilities
    • Zoghbi HY, Bear MF (2012) Synaptic dysfunction in neurodevelop-mental disorders associated with autism and intellectual disabilities. Cold Spring Harb Perspect Biol 4:a009886. CrossRef Medline
    • (2012) Cold Spring Harb Perspect Biol , vol.4
    • Zoghbi, H.Y.1    Bear, M.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.