Neural differentiation of fragile X human embryonic stem cells reveals abnormal patterns of development despite successful neurogenesis

Developmental Biology

Volumn 374, Issue 1, 2013, Pages 32-45

  Telias, Michael ^a,b   Segal, Menahem ^c   Ben Yosef, Dalit ^a,b  

^a LIS MATERNITY HOSPITAL   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Abnormal development; Fragile X syndrome; Human embryonic stem cells; Intellectual disability; Neural differentiation

Indexed keywords

FRAGILE X MENTAL RETARDATION PROTEIN;

ACTION POTENTIAL; ARTICLE; CELL LINEAGE; CELL MATURATION; DEVELOPMENTAL STAGE; DOWN REGULATION; EMBRYO; EMBRYONIC STEM CELL; FMR1 GENE; FRAGILE X SYNDROME; GENE EXPRESSION; GLIA; HUMAN; HUMAN CELL; IN VITRO STUDY; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEUROBLAST; PRIORITY JOURNAL; SYNAPTOGENESIS;

EID: 84872370488     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2012.11.031     Document Type: Article

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