-
1
-
-
60249086597
-
An update on the toxicity of Abeta in Alzheimer's disease
-
Gotz J., Ittner L.M., Schonrock N., Cappai R. An update on the toxicity of Abeta in Alzheimer's disease. Neuropsychiatr Dis Treat 2008, 4:1033-1042.
-
(2008)
Neuropsychiatr Dis Treat
, vol.4
, pp. 1033-1042
-
-
Gotz, J.1
Ittner, L.M.2
Schonrock, N.3
Cappai, R.4
-
2
-
-
47849124269
-
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways
-
Cogswell J.P., Ward J., Taylor I.A., Waters M., Shi Y., Cannon B., et al. Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. J Alzheimers Dis 2008, 14:27-41.
-
(2008)
J Alzheimers Dis
, vol.14
, pp. 27-41
-
-
Cogswell, J.P.1
Ward, J.2
Taylor, I.A.3
Waters, M.4
Shi, Y.5
Cannon, B.6
-
3
-
-
51149091628
-
MicroRNAs can regulate human APP levels
-
Patel N., Hoang D., Miller N., Ansaloni S., Huang Q., Rogers J.T., et al. MicroRNAs can regulate human APP levels. Mol Neurodegener 2008, 3:10-15.
-
(2008)
Mol Neurodegener
, vol.3
, pp. 10-15
-
-
Patel, N.1
Hoang, D.2
Miller, N.3
Ansaloni, S.4
Huang, Q.5
Rogers, J.T.6
-
4
-
-
84922678600
-
MicroRNA-135a and -200b, potential biomarkers for Alzheimer's disease, regulate β secretase and amyloid precursor protein
-
Liu C.G., Wang J.L., Li L., Xue L.X., Zhang Y.Q., Wang P.C. MicroRNA-135a and -200b, potential biomarkers for Alzheimer's disease, regulate β secretase and amyloid precursor protein. Brain Res 2014, 1583:55-64.
-
(2014)
Brain Res
, vol.1583
, pp. 55-64
-
-
Liu, C.G.1
Wang, J.L.2
Li, L.3
Xue, L.X.4
Zhang, Y.Q.5
Wang, P.C.6
-
5
-
-
84894450407
-
MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects
-
Long J.M., Ray B., Lahiri D.K. MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects. J Biol Chem 2014, 289:5184-5198.
-
(2014)
J Biol Chem
, vol.289
, pp. 5184-5198
-
-
Long, J.M.1
Ray, B.2
Lahiri, D.K.3
-
6
-
-
84864083653
-
MicroRNA-195 downregulates Alzheimer's disease amyloid-β production by targeting BACE1
-
Zhu H.C., Wang L.M., Wang M., Song B., Tan S., Teng J.F., et al. MicroRNA-195 downregulates Alzheimer's disease amyloid-β production by targeting BACE1. Brain Res Bull 2012, 88:596-601.
-
(2012)
Brain Res Bull
, vol.88
, pp. 596-601
-
-
Zhu, H.C.1
Wang, L.M.2
Wang, M.3
Song, B.4
Tan, S.5
Teng, J.F.6
-
7
-
-
84855177724
-
The miR-124 regulates the expression of BACE1/β-secretase correlated with cell death in Alzheimer's disease
-
Fang M., Wang J., Zhang X., Geng Y., Hu Z., Rudd J.A., et al. The miR-124 regulates the expression of BACE1/β-secretase correlated with cell death in Alzheimer's disease. Toxicol Lett 2012, 209:94-105.
-
(2012)
Toxicol Lett
, vol.209
, pp. 94-105
-
-
Fang, M.1
Wang, J.2
Zhang, X.3
Geng, Y.4
Hu, Z.5
Rudd, J.A.6
-
8
-
-
79957907210
-
MiR-29c regulates BACE1 protein expression
-
Zong Y., Wang H., Dong W., Quan X., Zhu H., Xu Y., et al. miR-29c regulates BACE1 protein expression. Brain Res 2011, 1395:108-115.
-
(2011)
Brain Res
, vol.1395
, pp. 108-115
-
-
Zong, Y.1
Wang, H.2
Dong, W.3
Quan, X.4
Zhu, H.5
Xu, Y.6
-
9
-
-
38749095507
-
The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1
-
Wang W.X., Rajeev B.W., Stromberg A.J., Ren N., Tang G., Huang Q., et al. The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J Neurosci 2008, 28:1213-1223.
-
(2008)
J Neurosci
, vol.28
, pp. 1213-1223
-
-
Wang, W.X.1
Rajeev, B.W.2
Stromberg, A.J.3
Ren, N.4
Tang, G.5
Huang, Q.6
-
10
-
-
72249114913
-
One-carbon metabolism-genome interactions in folate-associated pathologies
-
Stover P.J. One-carbon metabolism-genome interactions in folate-associated pathologies. J Nutr 2009, 139:2402-2405.
-
(2009)
J Nutr
, vol.139
, pp. 2402-2405
-
-
Stover, P.J.1
-
11
-
-
79953727039
-
Folate and homocysteine in the cerebrospinal fluid of patients with Alzheimer's disease or dementia: a case control study
-
Smach M.A., Jacob N., Golmard J.L., Charfeddine B., Lammouchi T., Ben Othman L., et al. Folate and homocysteine in the cerebrospinal fluid of patients with Alzheimer's disease or dementia: a case control study. Eur Neurol 2011, 65:270-278.
-
(2011)
Eur Neurol
, vol.65
, pp. 270-278
-
-
Smach, M.A.1
Jacob, N.2
Golmard, J.L.3
Charfeddine, B.4
Lammouchi, T.5
Ben Othman, L.6
-
12
-
-
57349148222
-
Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by dietary methionine without lowering plasma homocysteine
-
Troen A.M., Chao W.H., Crivello N.A., D'Anci K.E., Shukitt-Hale B., Smith D.E., et al. Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by dietary methionine without lowering plasma homocysteine. J Nutr 2008, 138:2502-2509.
-
(2008)
J Nutr
, vol.138
, pp. 2502-2509
-
-
Troen, A.M.1
Chao, W.H.2
Crivello, N.A.3
D'Anci, K.E.4
Shukitt-Hale, B.5
Smith, D.E.6
-
14
-
-
41249098662
-
B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-beta deposition in mice
-
Fuso A., Nicolia V., Cavallaro R.A., Ricceri L., D'Anselmi F., Coluccia P., et al. B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-beta deposition in mice. Mol Cell Neurosci 2008, 37:731-746.
-
(2008)
Mol Cell Neurosci
, vol.37
, pp. 731-746
-
-
Fuso, A.1
Nicolia, V.2
Cavallaro, R.A.3
Ricceri, L.4
D'Anselmi, F.5
Coluccia, P.6
-
15
-
-
33749479908
-
Downregulation of miR-122 in the rodent and human hepatocellular carcinomas
-
Kutay H., Bai S., Datta J., Motiwala T., Pogribny I., Frankel W., et al. Downregulation of miR-122 in the rodent and human hepatocellular carcinomas. J Cell Biochem 2006, 99:671-678.
-
(2006)
J Cell Biochem
, vol.99
, pp. 671-678
-
-
Kutay, H.1
Bai, S.2
Datta, J.3
Motiwala, T.4
Pogribny, I.5
Frankel, W.6
-
17
-
-
3042784367
-
Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia
-
Quadri P., Fragiacomo C., Pezzati R., Zanda E., Forloni G., Tettamanti M., et al. Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia. Am J Clin Nutr 2004, 80:114-122.
-
(2004)
Am J Clin Nutr
, vol.80
, pp. 114-122
-
-
Quadri, P.1
Fragiacomo, C.2
Pezzati, R.3
Zanda, E.4
Forloni, G.5
Tettamanti, M.6
-
18
-
-
84908127255
-
Folate deficiency-induced oxidative stress contributes to neuropathy in young and aged zebrafish - implication in neural tube defects and Alzheimer's diseases
-
Kao T.T., Chu C.Y., Lee G.H., Hsiao T.H., Cheng N.W., Chang N.S., et al. Folate deficiency-induced oxidative stress contributes to neuropathy in young and aged zebrafish - implication in neural tube defects and Alzheimer's diseases. Neurobiol Dis 2014, 71:234-244.
-
(2014)
Neurobiol Dis
, vol.71
, pp. 234-244
-
-
Kao, T.T.1
Chu, C.Y.2
Lee, G.H.3
Hsiao, T.H.4
Cheng, N.W.5
Chang, N.S.6
-
19
-
-
0036523032
-
Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease
-
Kruman I.I., Kumaravel T.S., Lohani A., Pedersen W.A., Cutler R.G., Kruman Y., et al. Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease. J Neurosci 2002, 22:1752-1762.
-
(2002)
J Neurosci
, vol.22
, pp. 1752-1762
-
-
Kruman, I.I.1
Kumaravel, T.S.2
Lohani, A.3
Pedersen, W.A.4
Cutler, R.G.5
Kruman, Y.6
-
20
-
-
79957965683
-
Cerebral perfusion and oxygenation are impaired by folate deficiency in rat: absolute measurements with noninvasive near-infrared spectroscopy
-
Hallacoglu B., Sassaroli A., Fantini S., Troen A.M. Cerebral perfusion and oxygenation are impaired by folate deficiency in rat: absolute measurements with noninvasive near-infrared spectroscopy. J Cereb Blood Flow Metab 2011, 31:1482-1492.
-
(2011)
J Cereb Blood Flow Metab
, vol.31
, pp. 1482-1492
-
-
Hallacoglu, B.1
Sassaroli, A.2
Fantini, S.3
Troen, A.M.4
-
21
-
-
78649872779
-
Changes in Presenilin 1 gene methylation pattern in diet-induced B vitamin deficiency
-
Fuso A., Nicolia V., Pasqualato A., Fiorenza M.T., Cavallaro R.A., Scarpa S. Changes in Presenilin 1 gene methylation pattern in diet-induced B vitamin deficiency. Neurobiol Aging 2011, 32:187-199.
-
(2011)
Neurobiol Aging
, vol.32
, pp. 187-199
-
-
Fuso, A.1
Nicolia, V.2
Pasqualato, A.3
Fiorenza, M.T.4
Cavallaro, R.A.5
Scarpa, S.6
-
22
-
-
79951677959
-
DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models
-
Fuso A., Nicolia V., Cavallaro R.A., Scarpa S. DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models. J Nutr Biochem 2011, 22:242-251.
-
(2011)
J Nutr Biochem
, vol.22
, pp. 242-251
-
-
Fuso, A.1
Nicolia, V.2
Cavallaro, R.A.3
Scarpa, S.4
-
23
-
-
84931573735
-
Folic acid administration inhibits amyloid β-peptide accumulation in APP/PS1 transgenic mice
-
Li W., Liu H., Yu M., Zhang X., Zhang M., Wilson J.X., et al. Folic acid administration inhibits amyloid β-peptide accumulation in APP/PS1 transgenic mice. J Nutr Biochem 2015, 26:883-891.
-
(2015)
J Nutr Biochem
, vol.26
, pp. 883-891
-
-
Li, W.1
Liu, H.2
Yu, M.3
Zhang, X.4
Zhang, M.5
Wilson, J.X.6
-
24
-
-
84925487085
-
Folic acid inhibits tau phosphorylation through regulation of PP2A methylation in SH-SY5Y cells
-
Li W., Jiang M., Xiao Y., Zhang X., Cui S., Huang G. Folic acid inhibits tau phosphorylation through regulation of PP2A methylation in SH-SY5Y cells. J Nutr Health Aging 2015, 19:123-129.
-
(2015)
J Nutr Health Aging
, vol.19
, pp. 123-129
-
-
Li, W.1
Jiang, M.2
Xiao, Y.3
Zhang, X.4
Cui, S.5
Huang, G.6
-
25
-
-
0028322017
-
An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
-
Suzuki N., Cheung T.T., Cai X.D., Odaka A., Otvos L., Eckman C., et al. An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Science 1994, 264:1336-1340.
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.D.3
Odaka, A.4
Otvos, L.5
Eckman, C.6
-
26
-
-
70149102204
-
Amyloid beta protein: Abeta40 inhibits Abeta42 oligomerization
-
Murray M.M., Bernstein S.L., Nyugen V., Condron M.M., TeplowD B., Bowers M.T. Amyloid beta protein: Abeta40 inhibits Abeta42 oligomerization. J Am Chem Soc 2009, 131:6316-6317.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 6316-6317
-
-
Murray, M.M.1
Bernstein, S.L.2
Nyugen, V.3
Condron, M.M.4
TeplowD, B.5
Bowers, M.T.6
-
27
-
-
84983197134
-
Folate deficiency accelerates Alzheimers disease related pathology in APP/PS1 mice
-
Crivello N., Jones T.S., Hale B.S., Carey A., Roe A., Smith D., et al. Folate deficiency accelerates Alzheimers disease related pathology in APP/PS1 mice. FASEB J 2013, 27:1077-1078.
-
(2013)
FASEB J
, vol.27
, pp. 1077-1078
-
-
Crivello, N.1
Jones, T.S.2
Hale, B.S.3
Carey, A.4
Roe, A.5
Smith, D.6
-
28
-
-
84929048523
-
Genome-wide analysis of miRNA signature in the APPswe/PS1δE9 mouse model of alzheimer's disease
-
Luo H., Wu Q., Ye X., Xiong Y., Zhu J., Xu J., et al. Genome-wide analysis of miRNA signature in the APPswe/PS1δE9 mouse model of alzheimer's disease. PLoS One 2014, 9:e101725.
-
(2014)
PLoS One
, vol.9
, pp. e101725
-
-
Luo, H.1
Wu, Q.2
Ye, X.3
Xiong, Y.4
Zhu, J.5
Xu, J.6
-
29
-
-
9244263071
-
BACE1 and presenilin: two unusual aspartyl proteases involved in Alzheimer's disease
-
Dominguez D.I., Hartmann D., De Strooper B. BACE1 and presenilin: two unusual aspartyl proteases involved in Alzheimer's disease. Neurodegener Dis 2004, 1:168-174.
-
(2004)
Neurodegener Dis
, vol.1
, pp. 168-174
-
-
Dominguez, D.I.1
Hartmann, D.2
De Strooper, B.3
-
30
-
-
0036718272
-
Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease
-
Fukumoto H., Cheung B.S., Hyman B.T., Irizarry M.C. Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease. Arch Neurol 2002, 59:1381-1389.
-
(2002)
Arch Neurol
, vol.59
, pp. 1381-1389
-
-
Fukumoto, H.1
Cheung, B.S.2
Hyman, B.T.3
Irizarry, M.C.4
-
31
-
-
0036260892
-
Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease
-
Holsinger R.M., McLean C.A., Beyreuther K., Masters C.L., Evin G. Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease. Ann Neurol 2002, 51:783-786.
-
(2002)
Ann Neurol
, vol.51
, pp. 783-786
-
-
Holsinger, R.M.1
McLean, C.A.2
Beyreuther, K.3
Masters, C.L.4
Evin, G.5
-
32
-
-
12144286502
-
Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients
-
Li R., Lindholm K., Yang L.B., Yue X., Citron M., Yan R., et al. Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients. Proc Natl Acad Sci U S A 2004, 101:3632-3637.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3632-3637
-
-
Li, R.1
Lindholm, K.2
Yang, L.B.3
Yue, X.4
Citron, M.5
Yan, R.6
-
33
-
-
84855435177
-
Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells
-
Chen L.M., Lin Z.Y., Zhu Y.G., Lin N., Zhang J., et al. Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells. Eur J Pharmacol. 2012, 675:15-21.
-
(2012)
Eur J Pharmacol.
, vol.675
, pp. 15-21
-
-
Chen, L.M.1
Lin, Z.Y.2
Zhu, Y.G.3
Lin, N.4
Zhang, J.5
|