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Volumn 26, Issue 12, 2015, Pages 1502-1508

Folic acid deficiency enhances abeta accumulation in APP/PS1 mice brain and decreases amyloid-associated miRNAs expression

Author keywords

Alzheimer's disease; Amyloid peptide; APP PS1 mice; Folic acid; MicroRNA

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; FOLIC ACID; MICRORNA; MICRORNA 106A-5P; MICRORNA 200B-3P; MICRORNA 399-5P; UNCLASSIFIED DRUG; ASPARTIC PROTEINASE; BACE1 PROTEIN, MOUSE; PRESENILIN 1; SECRETASE;

EID: 84983146543     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2015.07.020     Document Type: Article
Times cited : (35)

References (33)
  • 2
    • 47849124269 scopus 로고    scopus 로고
    • Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways
    • Cogswell J.P., Ward J., Taylor I.A., Waters M., Shi Y., Cannon B., et al. Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. J Alzheimers Dis 2008, 14:27-41.
    • (2008) J Alzheimers Dis , vol.14 , pp. 27-41
    • Cogswell, J.P.1    Ward, J.2    Taylor, I.A.3    Waters, M.4    Shi, Y.5    Cannon, B.6
  • 4
    • 84922678600 scopus 로고    scopus 로고
    • MicroRNA-135a and -200b, potential biomarkers for Alzheimer's disease, regulate β secretase and amyloid precursor protein
    • Liu C.G., Wang J.L., Li L., Xue L.X., Zhang Y.Q., Wang P.C. MicroRNA-135a and -200b, potential biomarkers for Alzheimer's disease, regulate β secretase and amyloid precursor protein. Brain Res 2014, 1583:55-64.
    • (2014) Brain Res , vol.1583 , pp. 55-64
    • Liu, C.G.1    Wang, J.L.2    Li, L.3    Xue, L.X.4    Zhang, Y.Q.5    Wang, P.C.6
  • 5
    • 84894450407 scopus 로고    scopus 로고
    • MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects
    • Long J.M., Ray B., Lahiri D.K. MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects. J Biol Chem 2014, 289:5184-5198.
    • (2014) J Biol Chem , vol.289 , pp. 5184-5198
    • Long, J.M.1    Ray, B.2    Lahiri, D.K.3
  • 6
    • 84864083653 scopus 로고    scopus 로고
    • MicroRNA-195 downregulates Alzheimer's disease amyloid-β production by targeting BACE1
    • Zhu H.C., Wang L.M., Wang M., Song B., Tan S., Teng J.F., et al. MicroRNA-195 downregulates Alzheimer's disease amyloid-β production by targeting BACE1. Brain Res Bull 2012, 88:596-601.
    • (2012) Brain Res Bull , vol.88 , pp. 596-601
    • Zhu, H.C.1    Wang, L.M.2    Wang, M.3    Song, B.4    Tan, S.5    Teng, J.F.6
  • 7
    • 84855177724 scopus 로고    scopus 로고
    • The miR-124 regulates the expression of BACE1/β-secretase correlated with cell death in Alzheimer's disease
    • Fang M., Wang J., Zhang X., Geng Y., Hu Z., Rudd J.A., et al. The miR-124 regulates the expression of BACE1/β-secretase correlated with cell death in Alzheimer's disease. Toxicol Lett 2012, 209:94-105.
    • (2012) Toxicol Lett , vol.209 , pp. 94-105
    • Fang, M.1    Wang, J.2    Zhang, X.3    Geng, Y.4    Hu, Z.5    Rudd, J.A.6
  • 8
    • 79957907210 scopus 로고    scopus 로고
    • MiR-29c regulates BACE1 protein expression
    • Zong Y., Wang H., Dong W., Quan X., Zhu H., Xu Y., et al. miR-29c regulates BACE1 protein expression. Brain Res 2011, 1395:108-115.
    • (2011) Brain Res , vol.1395 , pp. 108-115
    • Zong, Y.1    Wang, H.2    Dong, W.3    Quan, X.4    Zhu, H.5    Xu, Y.6
  • 9
    • 38749095507 scopus 로고    scopus 로고
    • The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1
    • Wang W.X., Rajeev B.W., Stromberg A.J., Ren N., Tang G., Huang Q., et al. The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J Neurosci 2008, 28:1213-1223.
    • (2008) J Neurosci , vol.28 , pp. 1213-1223
    • Wang, W.X.1    Rajeev, B.W.2    Stromberg, A.J.3    Ren, N.4    Tang, G.5    Huang, Q.6
  • 10
    • 72249114913 scopus 로고    scopus 로고
    • One-carbon metabolism-genome interactions in folate-associated pathologies
    • Stover P.J. One-carbon metabolism-genome interactions in folate-associated pathologies. J Nutr 2009, 139:2402-2405.
    • (2009) J Nutr , vol.139 , pp. 2402-2405
    • Stover, P.J.1
  • 11
    • 79953727039 scopus 로고    scopus 로고
    • Folate and homocysteine in the cerebrospinal fluid of patients with Alzheimer's disease or dementia: a case control study
    • Smach M.A., Jacob N., Golmard J.L., Charfeddine B., Lammouchi T., Ben Othman L., et al. Folate and homocysteine in the cerebrospinal fluid of patients with Alzheimer's disease or dementia: a case control study. Eur Neurol 2011, 65:270-278.
    • (2011) Eur Neurol , vol.65 , pp. 270-278
    • Smach, M.A.1    Jacob, N.2    Golmard, J.L.3    Charfeddine, B.4    Lammouchi, T.5    Ben Othman, L.6
  • 12
    • 57349148222 scopus 로고    scopus 로고
    • Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by dietary methionine without lowering plasma homocysteine
    • Troen A.M., Chao W.H., Crivello N.A., D'Anci K.E., Shukitt-Hale B., Smith D.E., et al. Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by dietary methionine without lowering plasma homocysteine. J Nutr 2008, 138:2502-2509.
    • (2008) J Nutr , vol.138 , pp. 2502-2509
    • Troen, A.M.1    Chao, W.H.2    Crivello, N.A.3    D'Anci, K.E.4    Shukitt-Hale, B.5    Smith, D.E.6
  • 14
    • 41249098662 scopus 로고    scopus 로고
    • B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-beta deposition in mice
    • Fuso A., Nicolia V., Cavallaro R.A., Ricceri L., D'Anselmi F., Coluccia P., et al. B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-beta deposition in mice. Mol Cell Neurosci 2008, 37:731-746.
    • (2008) Mol Cell Neurosci , vol.37 , pp. 731-746
    • Fuso, A.1    Nicolia, V.2    Cavallaro, R.A.3    Ricceri, L.4    D'Anselmi, F.5    Coluccia, P.6
  • 15
    • 33749479908 scopus 로고    scopus 로고
    • Downregulation of miR-122 in the rodent and human hepatocellular carcinomas
    • Kutay H., Bai S., Datta J., Motiwala T., Pogribny I., Frankel W., et al. Downregulation of miR-122 in the rodent and human hepatocellular carcinomas. J Cell Biochem 2006, 99:671-678.
    • (2006) J Cell Biochem , vol.99 , pp. 671-678
    • Kutay, H.1    Bai, S.2    Datta, J.3    Motiwala, T.4    Pogribny, I.5    Frankel, W.6
  • 17
    • 3042784367 scopus 로고    scopus 로고
    • Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia
    • Quadri P., Fragiacomo C., Pezzati R., Zanda E., Forloni G., Tettamanti M., et al. Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia. Am J Clin Nutr 2004, 80:114-122.
    • (2004) Am J Clin Nutr , vol.80 , pp. 114-122
    • Quadri, P.1    Fragiacomo, C.2    Pezzati, R.3    Zanda, E.4    Forloni, G.5    Tettamanti, M.6
  • 18
    • 84908127255 scopus 로고    scopus 로고
    • Folate deficiency-induced oxidative stress contributes to neuropathy in young and aged zebrafish - implication in neural tube defects and Alzheimer's diseases
    • Kao T.T., Chu C.Y., Lee G.H., Hsiao T.H., Cheng N.W., Chang N.S., et al. Folate deficiency-induced oxidative stress contributes to neuropathy in young and aged zebrafish - implication in neural tube defects and Alzheimer's diseases. Neurobiol Dis 2014, 71:234-244.
    • (2014) Neurobiol Dis , vol.71 , pp. 234-244
    • Kao, T.T.1    Chu, C.Y.2    Lee, G.H.3    Hsiao, T.H.4    Cheng, N.W.5    Chang, N.S.6
  • 19
    • 0036523032 scopus 로고    scopus 로고
    • Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease
    • Kruman I.I., Kumaravel T.S., Lohani A., Pedersen W.A., Cutler R.G., Kruman Y., et al. Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease. J Neurosci 2002, 22:1752-1762.
    • (2002) J Neurosci , vol.22 , pp. 1752-1762
    • Kruman, I.I.1    Kumaravel, T.S.2    Lohani, A.3    Pedersen, W.A.4    Cutler, R.G.5    Kruman, Y.6
  • 20
    • 79957965683 scopus 로고    scopus 로고
    • Cerebral perfusion and oxygenation are impaired by folate deficiency in rat: absolute measurements with noninvasive near-infrared spectroscopy
    • Hallacoglu B., Sassaroli A., Fantini S., Troen A.M. Cerebral perfusion and oxygenation are impaired by folate deficiency in rat: absolute measurements with noninvasive near-infrared spectroscopy. J Cereb Blood Flow Metab 2011, 31:1482-1492.
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 1482-1492
    • Hallacoglu, B.1    Sassaroli, A.2    Fantini, S.3    Troen, A.M.4
  • 22
    • 79951677959 scopus 로고    scopus 로고
    • DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models
    • Fuso A., Nicolia V., Cavallaro R.A., Scarpa S. DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models. J Nutr Biochem 2011, 22:242-251.
    • (2011) J Nutr Biochem , vol.22 , pp. 242-251
    • Fuso, A.1    Nicolia, V.2    Cavallaro, R.A.3    Scarpa, S.4
  • 23
    • 84931573735 scopus 로고    scopus 로고
    • Folic acid administration inhibits amyloid β-peptide accumulation in APP/PS1 transgenic mice
    • Li W., Liu H., Yu M., Zhang X., Zhang M., Wilson J.X., et al. Folic acid administration inhibits amyloid β-peptide accumulation in APP/PS1 transgenic mice. J Nutr Biochem 2015, 26:883-891.
    • (2015) J Nutr Biochem , vol.26 , pp. 883-891
    • Li, W.1    Liu, H.2    Yu, M.3    Zhang, X.4    Zhang, M.5    Wilson, J.X.6
  • 24
    • 84925487085 scopus 로고    scopus 로고
    • Folic acid inhibits tau phosphorylation through regulation of PP2A methylation in SH-SY5Y cells
    • Li W., Jiang M., Xiao Y., Zhang X., Cui S., Huang G. Folic acid inhibits tau phosphorylation through regulation of PP2A methylation in SH-SY5Y cells. J Nutr Health Aging 2015, 19:123-129.
    • (2015) J Nutr Health Aging , vol.19 , pp. 123-129
    • Li, W.1    Jiang, M.2    Xiao, Y.3    Zhang, X.4    Cui, S.5    Huang, G.6
  • 25
    • 0028322017 scopus 로고
    • An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
    • Suzuki N., Cheung T.T., Cai X.D., Odaka A., Otvos L., Eckman C., et al. An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Science 1994, 264:1336-1340.
    • (1994) Science , vol.264 , pp. 1336-1340
    • Suzuki, N.1    Cheung, T.T.2    Cai, X.D.3    Odaka, A.4    Otvos, L.5    Eckman, C.6
  • 27
    • 84983197134 scopus 로고    scopus 로고
    • Folate deficiency accelerates Alzheimers disease related pathology in APP/PS1 mice
    • Crivello N., Jones T.S., Hale B.S., Carey A., Roe A., Smith D., et al. Folate deficiency accelerates Alzheimers disease related pathology in APP/PS1 mice. FASEB J 2013, 27:1077-1078.
    • (2013) FASEB J , vol.27 , pp. 1077-1078
    • Crivello, N.1    Jones, T.S.2    Hale, B.S.3    Carey, A.4    Roe, A.5    Smith, D.6
  • 28
    • 84929048523 scopus 로고    scopus 로고
    • Genome-wide analysis of miRNA signature in the APPswe/PS1δE9 mouse model of alzheimer's disease
    • Luo H., Wu Q., Ye X., Xiong Y., Zhu J., Xu J., et al. Genome-wide analysis of miRNA signature in the APPswe/PS1δE9 mouse model of alzheimer's disease. PLoS One 2014, 9:e101725.
    • (2014) PLoS One , vol.9 , pp. e101725
    • Luo, H.1    Wu, Q.2    Ye, X.3    Xiong, Y.4    Zhu, J.5    Xu, J.6
  • 29
    • 9244263071 scopus 로고    scopus 로고
    • BACE1 and presenilin: two unusual aspartyl proteases involved in Alzheimer's disease
    • Dominguez D.I., Hartmann D., De Strooper B. BACE1 and presenilin: two unusual aspartyl proteases involved in Alzheimer's disease. Neurodegener Dis 2004, 1:168-174.
    • (2004) Neurodegener Dis , vol.1 , pp. 168-174
    • Dominguez, D.I.1    Hartmann, D.2    De Strooper, B.3
  • 30
    • 0036718272 scopus 로고    scopus 로고
    • Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease
    • Fukumoto H., Cheung B.S., Hyman B.T., Irizarry M.C. Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease. Arch Neurol 2002, 59:1381-1389.
    • (2002) Arch Neurol , vol.59 , pp. 1381-1389
    • Fukumoto, H.1    Cheung, B.S.2    Hyman, B.T.3    Irizarry, M.C.4
  • 31
    • 0036260892 scopus 로고    scopus 로고
    • Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease
    • Holsinger R.M., McLean C.A., Beyreuther K., Masters C.L., Evin G. Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease. Ann Neurol 2002, 51:783-786.
    • (2002) Ann Neurol , vol.51 , pp. 783-786
    • Holsinger, R.M.1    McLean, C.A.2    Beyreuther, K.3    Masters, C.L.4    Evin, G.5
  • 32
    • 12144286502 scopus 로고    scopus 로고
    • Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients
    • Li R., Lindholm K., Yang L.B., Yue X., Citron M., Yan R., et al. Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients. Proc Natl Acad Sci U S A 2004, 101:3632-3637.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 3632-3637
    • Li, R.1    Lindholm, K.2    Yang, L.B.3    Yue, X.4    Citron, M.5    Yan, R.6
  • 33
    • 84855435177 scopus 로고    scopus 로고
    • Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells
    • Chen L.M., Lin Z.Y., Zhu Y.G., Lin N., Zhang J., et al. Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells. Eur J Pharmacol. 2012, 675:15-21.
    • (2012) Eur J Pharmacol. , vol.675 , pp. 15-21
    • Chen, L.M.1    Lin, Z.Y.2    Zhu, Y.G.3    Lin, N.4    Zhang, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.