메뉴 건너뛰기




Volumn 1583, Issue 1, 2014, Pages 55-64

MicroRNA-135a and -200b, potential Biomarkers for Alzheimer's disease, regulate β secretase and amyloid precursor protein

Author keywords

Alzheimer's disease; Amyloid precursor protein; Microrna; secretase

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; MICRORNA; MICRORNA 135A; MICRORNA 200; MICRORNA 429; UNCLASSIFIED DRUG; APP PROTEIN, HUMAN; BIOLOGICAL MARKER; MIRN135 MICRORNA, HUMAN; MIRN135 MICRORNA, MOUSE; MIRN200 MICRORNA, HUMAN; MIRN200 MICRORNA, MOUSE; MIRN429 MICRORNA, HUMAN; MIRN429 MICRORNA, MOUSE; PRESENILIN 1; PSEN1 PROTEIN, HUMAN; SECRETASE;

EID: 84922678600     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2014.04.026     Document Type: Article
Times cited : (98)

References (40)
  • 1
    • 19944431428 scopus 로고    scopus 로고
    • Reductions in beta-amyloid concentrations in vivo by the gamma-secretase inhibitors BMS-289948 and BMS-299897
    • Anderson, J.J., et al., 2005. Reductions in beta-amyloid concentrations in vivo by the gamma-secretase inhibitors BMS-289948 and BMS-299897. Biochem. Pharmacol. 69 (4), 689-698.
    • (2005) Biochem. Pharmacol. , vol.69 , Issue.4 , pp. 689-698
    • Anderson, J.J.1
  • 2
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel, D.P., 2004. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116 (2), 281-297.
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 3
    • 77949423619 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
    • Blennow, K., et al., 2010. Cerebrospinal fluid and plasma biomarkers in Alzheimer disease. Nat. Rev. Neurol. 6 (3), 131-144.
    • (2010) Nat. Rev. Neurol. , vol.6 , Issue.3 , pp. 131-144
    • Blennow, K.1
  • 4
    • 79960364758 scopus 로고    scopus 로고
    • Oxygen-glucose deprivation increases the enzymatic activity and the microvesicle-mediated release of ectonucleotidases in the cells composing the blood-brain barrier
    • Ceruti, S., et al., 2011. Oxygen-glucose deprivation increases the enzymatic activity and the microvesicle-mediated release of ectonucleotidases in the cells composing the blood-brain barrier. Neurochem. Int. 59 (2), 259-271.
    • (2011) Neurochem. Int. , vol.59 , Issue.2 , pp. 259-271
    • Ceruti, S.1
  • 5
    • 84864987239 scopus 로고    scopus 로고
    • Alzheimer's p-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of p-amyloid
    • Chen, Y., et al., 2012. Alzheimer's p-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of p-amyloid. J. Neurosci. 32 (33), 11390-11395.
    • (2012) J. Neurosci. , vol.32 , Issue.33 , pp. 11390-11395
    • Chen, Y.1
  • 6
    • 84876719963 scopus 로고    scopus 로고
    • MicroRNAs (miRNAs) in colorectal cancer: From aberrant expression towards therapy
    • Dassow, H., Aigner, A., 2013. MicroRNAs (miRNAs) in colorectal cancer: from aberrant expression towards therapy. Curr. Pharm. Des. 19 (7), 1242-1252.
    • (2013) Curr. Pharm. Des. , vol.19 , Issue.7 , pp. 1242-1252
    • Dassow, H.1    Aigner, A.2
  • 7
    • 84859503786 scopus 로고    scopus 로고
    • MicroRNAs in Alzheimer's disease
    • Delay, C., et al., 2012. MicroRNAs in Alzheimer's disease. Neurobiol. Dis. 46 (2), 285-290.
    • (2012) Neurobiol. Dis. , vol.46 , Issue.2 , pp. 285-290
    • Delay, C.1
  • 8
    • 80053477918 scopus 로고    scopus 로고
    • Alzheimer-specific variants in the 3'UTR of Amyloid precursor protein affect microRNA function
    • Delay, C., et al., 2011. Alzheimer-specific variants in the 3'UTR of Amyloid precursor protein affect microRNA function. Mol. Neurodegener 6, 70.
    • (2011) Mol. Neurodegener , vol.6 , pp. 70
    • Delay, C.1
  • 9
    • 84863430273 scopus 로고    scopus 로고
    • The mammalian microRNA response to bacterial infections
    • Eulalio, A., Schulte, L., Vogel, J., 2012. The mammalian microRNA response to bacterial infections. RNA Biol. 9 (6), 742-750.
    • (2012) RNA Biol , vol.9 , Issue.6 , pp. 742-750
    • Eulalio, A.1    Schulte, L.2    Vogel, J.3
  • 10
    • 77957735016 scopus 로고    scopus 로고
    • Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration
    • Hebert, S.S., et al., 2010. Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration. Hum. Mol. Genet. 19 (20), 3959-3969.
    • (2010) Hum. Mol. Genet. , vol.19 , Issue.20 , pp. 3959-3969
    • Hebert, S.S.1
  • 11
    • 63349094897 scopus 로고    scopus 로고
    • Alterations of the microRNA network cause neurodegenerative disease
    • Hebert, S.S., De. Strooper, B., 2009. Alterations of the microRNA network cause neurodegenerative disease. Trends Neurosci. 32 (4), 199-206.
    • (2009) Trends Neurosci , vol.32 , Issue.4 , pp. 199-206
    • Hebert, S.S.1    De Strooper, B.2
  • 12
    • 84891112523 scopus 로고    scopus 로고
    • The future of blood-based biomarkers for Alzheimer's disease
    • Henriksen, K., et al., 2014. The future of blood-based biomarkers for Alzheimer's disease. Alzheimers Dement. 10, 115-131.
    • (2014) Alzheimers Dement , vol.10 , pp. 115-131
    • Henriksen, K.1
  • 13
    • 84856440598 scopus 로고    scopus 로고
    • MicroRNAs in neurodegenerative diseases and their therapeutic potential
    • Junn, E., Mouradian, M.M., 2012. MicroRNAs in neurodegenerative diseases and their therapeutic potential. Pharmacol. Ther. 133 (2), 142-150.
    • (2012) Pharmacol. Ther. , vol.133 , Issue.2 , pp. 142-150
    • Junn, E.1    Mouradian, M.M.2
  • 14
    • 77953556974 scopus 로고    scopus 로고
    • MicroRNAs in neurodegenerative disorders
    • Junn, E., Mouradian, M.M., 2010. MicroRNAs in neurodegenerative disorders. Cell Cycle 9 (9), 1717-1721.
    • (2010) Cell Cycle , vol.9 , Issue.9 , pp. 1717-1721
    • Junn, E.1    Mouradian, M.M.2
  • 15
    • 1642296212 scopus 로고    scopus 로고
    • Studies of Abeta pharmacodynamics in the brain, cerebrospinal fluid, and plasma in young (plaque-free) Tg2576 mice using the gamma-secretase inhibitor N2-[(2 S)-2- (3, 5-difluorophenyl)-2-hydroxyethanoyl]-N1-[(7 S)-5-methyl- 6-oxo-6, 7-dihydro-5 H-dibenzo[b, d]azepin-7-yl]-L- Alaninamide (LY-411575)
    • Lanz, T.A., et al., 2004. Studies of Abeta pharmacodynamics in the brain, cerebrospinal fluid, and plasma in young (plaque-free) Tg2576 mice using the gamma-secretase inhibitor N2-[(2 S)-2- (3, 5-difluorophenyl)-2-hydroxyethanoyl]-N1-[(7 S)-5-methyl- 6-oxo-6, 7-dihydro-5 H-dibenzo[b, d]azepin-7-yl]-L- Alaninamide (LY-411575). J. Pharmacol. Exp. Ther. 309 (1), 49-55.
    • (2004) J. Pharmacol. Exp. Ther. , vol.309 , Issue.1 , pp. 49-55
    • Lanz, T.A.1
  • 16
    • 34547970336 scopus 로고    scopus 로고
    • 17Beta-oestradiol regulates the expression of Na+/K+-ATPase beta1-subunit, sarcoplasmic reticulum Ca2+-ATPase and carbonic anhydrase iv in H9C2 cells
    • Liu, C.G., et al., 2007. 17Beta-oestradiol regulates the expression of Na+/K+-ATPase beta1-subunit, sarcoplasmic reticulum Ca2+-ATPase and carbonic anhydrase iv in H9C2 cells. Clin. Exp. Pharmacol. Physiol. 34 (10), 998-1004.
    • (2007) Clin. Exp. Pharmacol. Physiol. , vol.34 , Issue.10 , pp. 998-1004
    • Liu, C.G.1
  • 17
    • 0141843656 scopus 로고    scopus 로고
    • The nuclear RNase III Drosha initiates microRNA processing
    • Lee, Y., et al., 2003. The nuclear RNase III Drosha initiates microRNA processing. Nature 425 (6956), 415-419.
    • (2003) Nature , vol.425 , Issue.6956 , pp. 415-419
    • Lee, Y.1
  • 18
    • 0034014950 scopus 로고    scopus 로고
    • Single and multiple transgenic mice as models for Alzheimer's disease
    • Leuven, F., 2000. Single and multiple transgenic mice as models for Alzheimer's disease. Prog. Neurobiol. 61 (3), 305-312.
    • (2000) Prog. Neurobiol. , vol.61 , Issue.3 , pp. 305-312
    • Leuven, F.1
  • 19
    • 75549090428 scopus 로고    scopus 로고
    • Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: A multicenter study
    • Lewczuk, P., et al., 2010. Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: A multicenter study. Mol. Psychiatry 15 (2), 138-145.
    • (2010) Mol. Psychiatry , vol.15 , Issue.2 , pp. 138-145
    • Lewczuk, P.1
  • 20
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C(T)) method
    • Livak, K.J., Schmittgen, T.D., 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C(T)) method. Methods 25 (4), 402-408.
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 21
    • 79151483332 scopus 로고    scopus 로고
    • MicroRNA-101 downregulates Alzheimer's amyloid-p precursor protein levels in human cell cultures and is differentially expressed
    • Long, J.M., Lahiri, D.K., 2011. MicroRNA-101 downregulates Alzheimer's amyloid-p precursor protein levels in human cell cultures and is differentially expressed. Biochem. Biophys. Res. Commun. 404 (4), 889-895.
    • (2011) Biochem. Biophys. Res. Commun. , vol.404 , Issue.4 , pp. 889-895
    • Long, J.M.1    Lahiri, D.K.2
  • 22
    • 84862236784 scopus 로고    scopus 로고
    • Circulating microRNAs in cancer: Origin, function and application
    • Ma, R., Jiang, T., Kang, X., 2012. Circulating microRNAs in cancer: origin, function and application. J. Exp. Clin. Cancer Res. 31, 38.
    • (2012) J. Exp. Clin. Cancer Res. , vol.31 , pp. 38
    • Ma, R.1    Jiang, T.2    Kang, X.3
  • 23
    • 0037335461 scopus 로고    scopus 로고
    • Segregated expression of AMPA-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus
    • Matthias, K., et al., 2003. Segregated expression of AMPA-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus. J. Neurosci. 23 (5), 1750-1758.
    • (2003) J. Neurosci. , vol.23 , Issue.5 , pp. 1750-1758
    • Matthias, K.1
  • 24
    • 48749122914 scopus 로고    scopus 로고
    • Circulating microRNAs as stable blood- based markers for cancer detection
    • Mitchell, P.S., et al., 2008. Circulating microRNAs as stable blood- based markers for cancer detection. Proc. Natl. Acad. Sci. USA 105 (30), 10513-10518.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , Issue.30 , pp. 10513-10518
    • Mitchell, P.S.1
  • 25
    • 84858138492 scopus 로고    scopus 로고
    • Performance of ap1-40, ap1-42, total tau, and phosphorylated tau as predictors of dementia in a cohort of patients with mild cognitive impairment
    • Parnetti, L., et al., 2012. Performance of ap1-40, ap1-42, total tau, and phosphorylated tau as predictors of dementia in a cohort of patients with mild cognitive impairment. J. Alzheimers Dis. 29 (1), 229-238.
    • (2012) J. Alzheimers Dis. , vol.29 , Issue.1 , pp. 229-238
    • Parnetti, L.1
  • 26
    • 51149091628 scopus 로고    scopus 로고
    • MicroRNAs can regulate human APP levels
    • Patel, N., et al., 2008. MicroRNAs can regulate human APP levels. Mol. Neurodegener 3, 10.
    • (2008) Mol. Neurodegener , vol.3 , pp. 10
    • Patel, N.1
  • 27
    • 84860381680 scopus 로고    scopus 로고
    • MicroRNA networks surrounding APP and amyloid-p metabolism-implications for Alzheimer's disease
    • Schonrock, N., et al., 2012. MicroRNA networks surrounding APP and amyloid-p metabolism-implications for Alzheimer's disease. Exp. Neurol. 235 (2), 447-454.
    • (2012) Exp. Neurol. , vol.235 , Issue.2 , pp. 447-454
    • Schonrock, N.1
  • 28
    • 77956195348 scopus 로고    scopus 로고
    • Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-beta
    • Schonrock, N., et al., 2010. Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-beta. PLoS One 5 (6), e11070.
    • (2010) PLoS One , vol.5 , Issue.6 , pp. e11070
    • Schonrock, N.1
  • 29
    • 27744588007 scopus 로고    scopus 로고
    • Targeting BACE-1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model
    • Singer, O., et al., 2005. Targeting BACE-1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model. Nat. Neurosci. 8 (10), 1343-1349.
    • (2005) Nat. Neurosci. , vol.8 , Issue.10 , pp. 1343-1349
    • Singer, O.1
  • 30
    • 84891073424 scopus 로고    scopus 로고
    • Developing novel blood-based biomarkers for Alzheimer's disease
    • Snyder, H.M., et al., 2014. Developing novel blood-based biomarkers for Alzheimer's disease. Alzheimers Dement. 10, 109-114.
    • (2014) Alzheimers Dement , vol.10 , pp. 109-114
    • Snyder, H.M.1
  • 31
    • 0034697364 scopus 로고    scopus 로고
    • Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures
    • Stanciu, M., et al., 2000. Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures. J. Biol. Chem. 275 (16), 12200-12206.
    • (2000) J. Biol. Chem. , vol.275 , Issue.16 , pp. 12200-12206
    • Stanciu, M.1
  • 32
    • 84872501669 scopus 로고    scopus 로고
    • Non-coding RNAs in Alzheimer's disease
    • Tan, L., et al., 2013. Non-coding RNAs in Alzheimer's disease. Mol. Neurobiol. 47 (1), 382-393.
    • (2013) Mol. Neurobiol. , vol.47 , Issue.1 , pp. 382-393
    • Tan, L.1
  • 33
    • 84862192105 scopus 로고    scopus 로고
    • MicroRNAs in cerebrospinal fluid identify glioblastoma and metastatic brain cancers and reflect disease activity
    • Teplyuk, N.M., et al., 2012. MicroRNAs in cerebrospinal fluid identify glioblastoma and metastatic brain cancers and reflect disease activity. Neuro. Oncol. 14 (6), 689-700.
    • (2012) Neuro. Oncol. , vol.14 , Issue.6 , pp. 689-700
    • Teplyuk, N.M.1
  • 34
    • 79451474371 scopus 로고    scopus 로고
    • Patterns of microRNA expression in normal and early Alzheimer's disease human temporal cortex: White matter versus gray matter
    • Wang, W.X., et al., 2011. Patterns of microRNA expression in normal and early Alzheimer's disease human temporal cortex: white matter versus gray matter. Acta. Neuropathol. 121 (2), 193-205.
    • (2011) Acta. Neuropathol. , vol.121 , Issue.2 , pp. 193-205
    • Wang, W.X.1
  • 35
    • 80052299230 scopus 로고    scopus 로고
    • Matrix metalloproteinase-12 leads to elastin degradation in BALB/c mice with eosinophilic meningitis caused by Angiostrongylus cantonensis
    • Wei, P.C., et al., 2011. Matrix metalloproteinase-12 leads to elastin degradation in BALB/c mice with eosinophilic meningitis caused by Angiostrongylus cantonensis. Int. J. Parasitol. 41 (11), 1175-1183.
    • (2011) Int. J. Parasitol. , vol.41 , Issue.11 , pp. 1175-1183
    • Wei, P.C.1
  • 36
    • 79955544309 scopus 로고    scopus 로고
    • Calcium signaling is involved in cadmium- induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network
    • Xu, B., et al., 2011. Calcium signaling is involved in cadmium- induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network. PLoS One 6 (4), e19052.
    • (2011) PLoS One , vol.6 , Issue.4 , pp. e19052
    • Xu, B.1
  • 37
    • 0037236622 scopus 로고    scopus 로고
    • Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease
    • Yang, L.B., et al., 2003. Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease. Nat. Med. 9 (1), 3-4.
    • (2003) Nat. Med. , vol.9 , Issue.1 , pp. 3-4
    • Yang, L.B.1
  • 38
    • 49449108546 scopus 로고    scopus 로고
    • Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease
    • Zetterberg, H., et al., 2008. Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease. Arch. Neurol. 65 (8), 1102-1107.
    • (2008) Arch. Neurol. , vol.65 , Issue.8 , pp. 1102-1107
    • Zetterberg, H.1
  • 39
    • 77954257796 scopus 로고    scopus 로고
    • Secreted monocytic miR-150 enhances targeted endothelial cell migration
    • Zhang, Y., et al., 2010. Secreted monocytic miR-150 enhances targeted endothelial cell migration. Mol. Cell 39 (1), 133-144.
    • (2010) Mol. Cell , vol.39 , Issue.1 , pp. 133-144
    • Zhang, Y.1
  • 40
    • 34249942064 scopus 로고    scopus 로고
    • Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment
    • Zhong, Z., et al., 2007. Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment. Arch. Gen. Psychiatr. 64 (6), 718-726.
    • (2007) Arch. Gen. Psychiatr. , vol.64 , Issue.6 , pp. 718-726
    • Zhong, Z.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.