Osteopontin Promotes Hepatic Progenitor Cell Expansion and Tumorigenicity via Activation of β-Catenin in Mice

Stem Cells

Volumn 33, Issue 12, 2015, Pages 3569-3580

  Liu, Yingying ^a,b   Cao, Lei ^a,c   Chen, Rui ^a   Zhou, Xuyu ^b   Fan, Xiaoyu ^a   Liang, Yingchao ^a   Jia, Rongjie ^a   Wang, Hao ^a   Liu, Guoke ^a   Guo, Yajun ^a,d,e   Zhao, Jian ^a,d,e  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^d CHINESE PLA GENERAL HOSPITAL   (China)

^e PEKING UNIVERSITY   (China)

Author keywords

Epithelial mesenchymal transition; Hepatic progenitor cell; Hepatocarcinogenesis; Osteopontin

Indexed keywords

ALPHA5 INTEGRIN; BETA CATENIN; CD45 ANTIGEN; CHOLINE; CYCLINE; EPITHELIAL CELL ADHESION MOLECULE; ETHIONINE; NUCLEIC ACID BINDING PROTEIN; OSTEOPONTIN; RNA; UNCLASSIFIED DRUG; UVOMORULIN; Y BOX BINDING PROTEIN 9; SPP1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE DUCT CARCINOMA; CARCINOGENESIS; CARCINOGENICITY; CELL DIFFERENTIATION; CELL EXPANSION; CELL MIGRATION; CELL VIABILITY; CONTROLLED STUDY; DIET SUPPLEMENTATION; EPITHELIAL MESENCHYMAL TRANSITION; GENE INACTIVATION; HEPATIC PROGENITOR CELL; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IN VITRO STUDY; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER EPITHELIAL PROGENITOR CELL; LIVER INJURY; MALE; MOUSE; NONHUMAN; ONCOGENE SRC; PROTEIN DEPLETION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WILD TYPE; ANIMAL; AUTOCRINE EFFECT; CELL LINE; CELL TRANSFORMATION; GENETICS; KNOCKOUT MOUSE; LIVER; LIVER TUMOR; METABOLISM; PATHOLOGY; STEM CELL;

ANIMALS; AUTOCRINE COMMUNICATION; BETA CATENIN; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; HUMANS; LIVER; LIVER NEOPLASMS; MALE; MICE; MICE, KNOCKOUT; OSTEOPONTIN; STEM CELLS;

EID: 84983094909     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2072     Document Type: Article

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