-
1
-
-
31544457103
-
Mechanisms of disease: Is osteoporosis the obesity of bone?
-
Rosen CJ, Bouxsein ML. Mechanisms of disease: Is osteoporosis the obesity of bone? Nature Clin Pract Rheumatol 2006;2: 35-43.
-
(2006)
Nature Clin Pract Rheumatol
, vol.2
, pp. 35-43
-
-
Rosen, C.J.1
Bouxsein, M.L.2
-
2
-
-
0015137446
-
Osteoporosis and the replacement of cell populations of the marrow by adipose tissue-A quantitative study of 84 iliac bone biopsies
-
Meunier P, Aaron J, Edouard C et al. Osteoporosis and the replacement of cell populations of the marrow by adipose tissue-A quantitative study of 84 iliac bone biopsies. Clin Orthop Relat Res 1971;80: 147-154.
-
(1971)
Clin Orthop Relat Res
, vol.80
, pp. 147-154
-
-
Meunier, P.1
Aaron, J.2
Edouard, C.3
-
3
-
-
49649118727
-
The bone-adipose axis in obesity and weight loss
-
Gomez-Ambrosi J, Rodriguez A, Catalan V et al. The bone-adipose axis in obesity and weight loss. Obes Surg 2008;18: 1134-1143.
-
(2008)
Obes Surg
, vol.18
, pp. 1134-1143
-
-
Gomez-Ambrosi, J.1
Rodriguez, A.2
Catalan, V.3
-
4
-
-
0034842784
-
Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis
-
Justesen J, Stenderup K, Ebbesen EN et al. Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis. Biogerontology 2001;2: 165-171.
-
(2001)
Biogerontology
, vol.2
, pp. 165-171
-
-
Justesen, J.1
Stenderup, K.2
Ebbesen, E.N.3
-
5
-
-
13244255379
-
Steroid effects on osteogenesis through mesenchymal cell gene expression
-
Li XD, Jin L, Cui QJ et al. Steroid effects on osteogenesis through mesenchymal cell gene expression. Osteoporos Int 2005;16: 101-108.
-
(2005)
Osteoporos Int
, vol.16
, pp. 101-108
-
-
Li, X.D.1
Jin, L.2
Cui, Q.J.3
-
7
-
-
33745503987
-
Mesenchymal stem cells reside in virtually all post-natal organs and tissues
-
Meirelles LDS, Chagastelles PC, Nardi NB. Mesenchymal stem cells reside in virtually all post-natal organs and tissues. J Cell Sci 2006;119: 2204-2213.
-
(2006)
J Cell Sci
, vol.119
, pp. 2204-2213
-
-
Meirelles, L.D.S.1
Chagastelles, P.C.2
Nardi, N.B.3
-
8
-
-
38649105374
-
Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide
-
Ren GW, Zhang LY, Zhao X et al. Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide. Cell Stem Cell 2008;2: 141-150.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 141-150
-
-
Ren, G.W.1
Zhang, L.Y.2
Zhao, X.3
-
9
-
-
0037019337
-
Pluripotency of mesenchymal stem cells derived from adult marrow
-
Jiang Y, Jahagirdar BN, Reinhardt RL et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418: 41-49.
-
(2002)
Nature
, vol.418
, pp. 41-49
-
-
Jiang, Y.1
Jahagirdar, B.N.2
Reinhardt, R.L.3
-
10
-
-
0033515827
-
Multilineage potential of adult human mesenchymal stem cells
-
Pittenger MF, Mackay AM, Beck SC et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284: 143-147.
-
(1999)
Science
, vol.284
, pp. 143-147
-
-
Pittenger, M.F.1
Mackay, A.M.2
Beck, S.C.3
-
11
-
-
84855517156
-
Mesenchymal stem cell-based tissue regeneration is governed by recipient t lymphocytes via ifngamma and tnf-alpha
-
Liu Y, Wang L, Kikuiri T et al. Mesenchymal stem cell-based tissue regeneration is governed by recipient T lymphocytes via IFNgamma and TNF-alpha. Nat Med 2011;17: 1594-1601.
-
(2011)
Nat Med
, vol.17
, pp. 1594-1601
-
-
Liu, Y.1
Wang, L.2
Kikuiri, T.3
-
12
-
-
0142026448
-
Controlling mesenchymal stem cell differentiation by tgf-beta family members
-
Roelen BA, Dijke P. Controlling mesenchymal stem cell differentiation by TGF-beta family members. J Orthop Sci 2003;8: 740-748.
-
(2003)
J Orthop Sci
, vol.8
, pp. 740-748
-
-
Roelen, B.A.1
Dijke, P.2
-
13
-
-
3042722241
-
Adhesion to vitronectin and collagen i promotes osteogenic differentiation of human mesenchymal stem cells
-
Salasznyk RM, Williams WA, Boskey A et al. Adhesion to vitronectin and collagen I promotes osteogenic differentiation of human mesenchymal stem cells. J Biomed Biotechnol 2004: 24-34.
-
(2004)
J Biomed Biotechnol
, pp. 24-34
-
-
Salasznyk, R.M.1
Williams, W.A.2
Boskey, A.3
-
14
-
-
0036090467
-
Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation
-
Lecka-Czernik B, Moerman EJ, Grant DF et al. Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation. Endocrinology 2002;143: 2376-2384.
-
(2002)
Endocrinology
, vol.143
, pp. 2376-2384
-
-
Lecka-Czernik, B.1
Moerman, E.J.2
Grant, D.F.3
-
15
-
-
0242664267
-
Msx2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors
-
Cheng SL, Shao JS, Charlton-Kachigian N et al. Msx2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors. J Biol Chem 2003;278: 45969-45977.
-
(2003)
J Biol Chem
, vol.278
, pp. 45969-45977
-
-
Cheng, S.L.1
Shao, J.S.2
Charlton-Kachigian, N.3
-
16
-
-
57049166456
-
Osteopontin: Role in immune regulation and stress responses
-
Wang KX, Denhardt DT. Osteopontin: Role in immune regulation and stress responses. Cytokine Growth Factor Rev 2008; 19: 333-345.
-
(2008)
Cytokine Growth Factor Rev
, vol.19
, pp. 333-345
-
-
Wang, K.X.1
Denhardt, D.T.2
-
17
-
-
0032432558
-
Osteopontin expression and function: Role in bone remodeling
-
Denhardt DT, Noda M. Osteopontin expression and function: Role in bone remodeling. J Cell Biochem 1998;72: 92-102.
-
(1998)
J Cell Biochem
, vol.72
, pp. 92-102
-
-
Denhardt, D.T.1
Noda, M.2
-
18
-
-
35548995858
-
Osteopontin regulates hindlimb-unloading-induced lymphoid organ atrophy and weight loss by modulating corticosteroid production
-
Wang KX, Shi YF, Denhardt DT. Osteopontin regulates hindlimb-unloading- induced lymphoid organ atrophy and weight loss by modulating corticosteroid production. Proc Natl Acad Sci USA 2007;104: 14777-14782.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14777-14782
-
-
Wang, K.X.1
Shi, Y.F.2
Denhardt, D.T.3
-
19
-
-
0000022154
-
Altered wound healing in mice lacking a functional osteopontin gene (spp1)
-
Liaw L, Birk DE, Ballas CB et al. Altered wound healing in mice lacking a functional osteopontin gene (SPP1). J Clin Invest 1998; 101: 1468-1478.
-
(1998)
J Clin Invest
, vol.101
, pp. 1468-1478
-
-
Liaw, L.1
Birk, D.E.2
Ballas, C.B.3
-
20
-
-
2942511574
-
Role of osteopontin in tumour progression
-
Rittling SR, Chambers AF. Role of osteopontin in tumour progression. Br J Cancer 2004;90: 1877-1881.
-
(2004)
Br J Cancer
, vol.90
, pp. 1877-1881
-
-
Rittling, S.R.1
Chambers, A.F.2
-
21
-
-
0035941106
-
The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease
-
Chabas D, Baranzini SE, Mitchell D et al. The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science 2001;294: 1731-1735.
-
(2001)
Science
, vol.294
, pp. 1731-1735
-
-
Chabas, D.1
Baranzini, S.E.2
Mitchell, D.3
-
22
-
-
0028117413
-
Induction of rapid osteoblast differentiation in rat bone marrow stromal cell cultures by dexamethasone and bmp-2
-
Rickard DJ, Sullivan TA, Shenker BJ et al. Induction of rapid osteoblast differentiation in rat bone marrow stromal cell cultures by dexamethasone and BMP-2. Dev Biol 1994; 161: 218-228.
-
(1994)
Dev Biol
, vol.161
, pp. 218-228
-
-
Rickard, D.J.1
Sullivan, T.A.2
Shenker, B.J.3
-
23
-
-
0031836772
-
Mice lacking osteopontin show normal development and bone structure but display altered osteoclast formation in vitro
-
Rittling SR, Matsumoto HN, McKee MD et al. Mice lacking osteopontin show normal development and bone structure but display altered osteoclast formation in vitro. J Bone Miner Res 1998;13: 1101-1111.
-
(1998)
J Bone Miner Res
, vol.13
, pp. 1101-1111
-
-
Rittling, S.R.1
Matsumoto, H.N.2
McKee, M.D.3
-
24
-
-
35648934023
-
Control of osteopontin signaling and function by post-translational phosphorylation and protein folding
-
Kazanecki CC, Uzwiak DJ, Denhardt DT. Control of osteopontin signaling and function by post-translational phosphorylation and protein folding. J Cell Biochem 2007;102: 912-924.
-
(2007)
J Cell Biochem
, vol.102
, pp. 912-924
-
-
Kazanecki, C.C.1
Uzwiak, D.J.2
Denhardt, D.T.3
-
25
-
-
69249119079
-
Species variation in the mechanisms of mesenchymal stem cell-mediated immunosuppression
-
Ren GW, Su JJ, Zhang LY et al. Species variation in the mechanisms of mesenchymal stem cell-mediated immunosuppression. Stem Cells 2009;27: 1954-1962.
-
(2009)
Stem Cells
, vol.27
, pp. 1954-1962
-
-
Ren, G.W.1
Su, J.J.2
Zhang, L.Y.3
-
26
-
-
33947309773
-
Immunosuppressive properties of cloned bone marrow mesenchymal stem cells
-
Xu GW, Zhang LY, Ren GW et al. Immunosuppressive properties of cloned bone marrow mesenchymal stem cells. Cell Res 2007;17: 240-248.
-
(2007)
Cell Res
, vol.17
, pp. 240-248
-
-
Xu, G.W.1
Zhang, L.Y.2
Ren, G.W.3
-
27
-
-
35649014332
-
Characterization of anti-osteopontin monoclonal antibodies: Binding sensitivity to posttranslational modifications
-
Kazanecki CC, Kowalski AJ, Ding T et al. Characterization of anti-osteopontin monoclonal antibodies: Binding sensitivity to posttranslational modifications. J Cell Biochem 2007;102: 925-935.
-
(2007)
J Cell Biochem
, vol.102
, pp. 925-935
-
-
Kazanecki, C.C.1
Kowalski, A.J.2
Ding, T.3
-
28
-
-
0028853560
-
A biochemical characterization of the binding of osteopontin to integrins alpha v beta 1 and alpha v beta 5
-
Hu DD, Lin ECK, Kovach NL et al. A biochemical characterization of the binding of osteopontin to integrins alpha v beta 1 and alpha v beta 5. J Biol Chem 1995;270: 26232-26238.
-
(1995)
J Biol Chem
, vol.270
, pp. 26232-26238
-
-
Hu, D.D.1
Lin, E.C.K.2
Kovach, N.L.3
-
29
-
-
0029007036
-
Engagement of the osteoclast integrin alpha v beta 3 by osteopontin stimulates phosphatidylinositol 3-hydroxyl kinase activity
-
Hruska KA, Rolnick F, Huskey M et al. Engagement of the osteoclast integrin alpha v beta 3 by osteopontin stimulates phosphatidylinositol 3-hydroxyl kinase activity. Endocrinology 1995;136: 2984-2992.
-
(1995)
Endocrinology
, vol.136
, pp. 2984-2992
-
-
Hruska, K.A.1
Rolnick, F.2
Huskey, M.3
-
30
-
-
0028878375
-
Cascade regulation of terminal adipocyte differentiation by three members of the c/ebp family of leucine zipper proteins
-
Yeh WC, Cao Z, Classon M et al. Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. Genes Dev 1995;9: 168-181.
-
(1995)
Genes Dev
, vol.9
, pp. 168-181
-
-
Yeh, W.C.1
Cao, Z.2
Classon, M.3
-
31
-
-
33845325476
-
Adipocyte differentiation from the inside out
-
Rosen ED, MacDougald OA. Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol 2006;7: 885-896.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 885-896
-
-
Rosen, E.D.1
MacDougald, O.A.2
-
32
-
-
79961146419
-
A novel role for neural cell adhesion molecule in modulating insulin signaling and adipocyte differentiation of mouse mesenchymal stem cells
-
Yang HJ, Xia YY, Wang L et al. A novel role for neural cell adhesion molecule in modulating insulin signaling and adipocyte differentiation of mouse mesenchymal stem cells. J Cell Sci 2011;124: 2552-2560.
-
(2011)
J Cell Sci
, vol.124
, pp. 2552-2560
-
-
Yang, H.J.1
Xia, Y.Y.2
Wang, L.3
-
33
-
-
0028564903
-
Ccaat/enhancer binding protein alpha is sufficient to initiate the 3t3-l1 adipocyte differentiation program
-
Lin FT, Lane MD. CCAAT/enhancer binding protein alpha is sufficient to initiate the 3T3-L1 adipocyte differentiation program. Proc Natl Acad Sci USA 1994;91: 8757-8761.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8757-8761
-
-
Lin, F.T.1
Lane, M.D.2
-
34
-
-
23244450048
-
The relationship between serum resistin, leptin, adiponectin, ghrelin levels and bone mineral density in middle-aged men
-
Oh KW, Lee WY, Rhee EJ et al. The relationship between serum resistin, leptin, adiponectin, ghrelin levels and bone mineral density in middle-aged men. Clin Endocrinol 2005;63: 131-138.
-
(2005)
Clin Endocrinol
, vol.63
, pp. 131-138
-
-
Oh, K.W.1
Lee, W.Y.2
Rhee, E.J.3
-
35
-
-
34547690686
-
Endocrine regulation of energy metabolism by the skeleton
-
Lee NK, Sowa H, Hinoi E et al. Endocrine regulation of energy metabolism by the skeleton. Cell 2007;130: 456-469.
-
(2007)
Cell
, vol.130
, pp. 456-469
-
-
Lee, N.K.1
Sowa, H.2
Hinoi, E.3
-
36
-
-
84866300463
-
The importance of the sibling family of proteins on skeletal mineralisation and bone remodelling
-
Staines KA, MacRae VE, Farquharson C. The importance of the SIBLING family of proteins on skeletal mineralisation and bone remodelling. J Endocrinol 2012;214: 241-255.
-
(2012)
J Endocrinol
, vol.214
, pp. 241-255
-
-
Staines, K.A.1
MacRae, V.E.2
Farquharson, C.3
-
37
-
-
0031013634
-
Single cell analysis of intracellular osteopontin in osteogenic cultures of fetal rat calvarial cells
-
Zohar R, Lee W, Arora P et al. Single cell analysis of intracellular osteopontin in osteogenic cultures of fetal rat calvarial cells. J Cell Physiol 1997;170: 88-100.
-
(1997)
J Cell Physiol
, vol.170
, pp. 88-100
-
-
Zohar, R.1
Lee, W.2
Arora, P.3
-
38
-
-
0031613168
-
Analysis of intracellular osteopontin as a marker of osteoblastic cell differentiation and mesenchymal cell migration
-
Zohar R, Cheifetz S, McCulloch CAG et al. Analysis of intracellular osteopontin as a marker of osteoblastic cell differentiation and mesenchymal cell migration. Eur J Oral Sci 1998;106: 401-407.
-
(1998)
Eur J Oral Sci
, vol.106
, pp. 401-407
-
-
Zohar, R.1
Cheifetz, S.2
McCulloch, C.A.G.3
-
39
-
-
0034093124
-
Intracellular osteopontin is an integral component of the cd44-erm complex involved in cell migration
-
Zohar R, Suzuki N, Suzuki K et al. Intracellular osteopontin is an integral component of the CD44-ERM complex involved in cell migration. J Cell Physiol 2000;184: 118-130.
-
(2000)
J Cell Physiol
, vol.184
, pp. 118-130
-
-
Zohar, R.1
Suzuki, N.2
Suzuki, K.3
-
40
-
-
0037199987
-
Integrins alpha 6a beta 1 and alpha 6b beta 1 promote different stages of chondrogenic cell differentiation
-
Segat D, Comai R, Di Marco E et al. Integrins alpha 6A beta 1 and alpha 6B beta 1 promote different stages of chondrogenic cell differentiation. J Biol Chem 2002;277: 31612-31622.
-
(2002)
J Biol Chem
, vol.277
, pp. 31612-31622
-
-
Segat, D.1
Comai, R.2
Di Marco, E.3
-
41
-
-
0033551899
-
Transduction-integrin signaling
-
Giancotti FG, Ruoslahti E. Transduction-Integrin signaling. Science 1999;285: 1028-1032.
-
(1999)
Science
, vol.285
, pp. 1028-1032
-
-
Giancotti, F.G.1
Ruoslahti, E.2
-
42
-
-
57749206799
-
Controlling integrin specificity and stem cell differentiation in 2d and 3d environments through regulation of fibronectin domain stability
-
Martino MM, Mochizuki M, Rothenfluh DA et al. Controlling integrin specificity and stem cell differentiation in 2D and 3D environments through regulation of fibronectin domain stability. Biomaterials 2009;30: 1089-1097.
-
(2009)
Biomaterials
, vol.30
, pp. 1089-1097
-
-
Martino, M.M.1
Mochizuki, M.2
Rothenfluh, D.A.3
-
43
-
-
33847375078
-
Critical role of the extracellular signal-regulated kinase-mapk pathway in osteoblast differentiation and skeletal development
-
Ge CX, Xiao GZ, Jiang D et al. Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development. J Cell Biol 2007;176: 709-718.
-
(2007)
J Cell Biol
, vol.176
, pp. 709-718
-
-
Ge, C.X.1
Xiao, G.Z.2
Jiang, D.3
-
44
-
-
62149135284
-
Characterisation and developmental potential of ovine bone marrow derived mesenchymal stem cells
-
McCarty RC, Gronthos S, Zannettino AC et al. Characterisation and developmental potential of ovine bone marrow derived mesenchymal stem cells. J Cell Physiol 2009;219: 324-333.
-
(2009)
J Cell Physiol
, vol.219
, pp. 324-333
-
-
McCarty, R.C.1
Gronthos, S.2
Zannettino, A.C.3
-
45
-
-
2342628515
-
Human adipose-derived adult stem cells produce osteoid in vivo
-
Hicok KC, Du Laney TV, Zhou YS et al. Human adipose-derived adult stem cells produce osteoid in vivo. Tissue Eng 2004;10: 371-380.
-
(2004)
Tissue Eng
, vol.10
, pp. 371-380
-
-
Hicok, K.C.1
Du Laney, T.V.2
Zhou, Y.S.3
-
46
-
-
0038664242
-
Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow
-
Gronthos S, Zannettino AC, Hay SJ et al. Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow. J Cell Sci 2003; 116: 1827-1835.
-
(2003)
J Cell Sci
, vol.116
, pp. 1827-1835
-
-
Gronthos, S.1
Zannettino, A.C.2
Hay, S.J.3
-
47
-
-
0029583657
-
Vitronectin is not essential for normal mammalian development and fertility
-
Zheng X, Saunders TL, Camper SA et al. Vitronectin is not essential for normal mammalian development and fertility. Proc Natl Acad Sci USA 1995;92: 12426-12430.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 12426-12430
-
-
Zheng, X.1
Saunders, T.L.2
Camper, S.A.3
-
48
-
-
78649759561
-
Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice
-
Chapman J, Miles PD, Ofrecio JM et al. Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice. PLoS One 2010;5: e13959.
-
(2010)
PLoS One
, vol.5
-
-
Chapman, J.1
Miles, P.D.2
Ofrecio, J.M.3
-
49
-
-
79960901954
-
Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice
-
Kiefer FW, Neschen S, Pfau B et al. Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice. Diabetologia 2011;54: 2132-2142.
-
(2011)
Diabetologia
, vol.54
, pp. 2132-2142
-
-
Kiefer, F.W.1
Neschen, S.2
Pfau, B.3
-
51
-
-
21344474104
-
Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells
-
Nilsson SK, Johnston HM, Whitty GA et al. Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells. Blood 2005;106: 1232-1239.
-
(2005)
Blood
, vol.106
, pp. 1232-1239
-
-
Nilsson, S.K.1
Johnston, H.M.2
Whitty, G.A.3
-
52
-
-
21244472780
-
Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size
-
Stier S, Ko Y, Forkert F et al. Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size. J Exp Med 2005;201: 1781-1791.
-
(2005)
J Exp Med
, vol.201
, pp. 1781-1791
-
-
Stier, S.1
Ko, Y.2
Forkert, F.3
-
53
-
-
0242268524
-
Osteoblastic cells regulate the haematopoietic stem cell niche
-
Calvi LM, Adams GB, Weibrecht KW et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 2003;425: 841-846.
-
(2003)
Nature
, vol.425
, pp. 841-846
-
-
Calvi, L.M.1
Adams, G.B.2
Weibrecht, K.W.3
-
54
-
-
0242363225
-
Identification of the haematopoietic stem cell niche and control of the niche size
-
Zhang JW, Niu C, Ye L et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 2003; 425: 836-841.
-
(2003)
Nature
, vol.425
, pp. 836-841
-
-
Zhang, J.W.1
Niu, C.2
Ye, L.3
-
55
-
-
67650504733
-
Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment
-
Naveiras O, Nardi V, Wenzel PL et al. Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment. Nature 2009;460: 259-263.
-
(2009)
Nature
, vol.460
, pp. 259-263
-
-
Naveiras, O.1
Nardi, V.2
Wenzel, P.L.3
|