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Volumn 7, Issue 1, 2015, Pages

The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain

(25)  Pangeni, Rajendra P a   Channathodiyil, Prasanna a   Huen, David S a   Eagles, Lawrence W a   Johal, Balraj K a   Pasha, Dawar a   Hadjistephanou, Natasa a   Nevell, Oliver a   Davies, Claire L a   Adewumi, Ayobami I a   Khanom, Hamida a   Samra, Ikroop S a   Buzatto, Vanessa C a   Chandrasekaran, Preethi a   Shinawi, Thoraia b   Dawson, Timothy P c   Ashton, Katherine M c   Davis, Charles c   Brodbelt, Andrew R d   Jenkinson, Michael D d   more..


Author keywords

Brain; Breast; DNA methylation; Epigenetic; Metastasis; Tumour suppressor

Indexed keywords

RNA;

EID: 84983085318     PISSN: 18687075     EISSN: 18687083     Source Type: Journal    
DOI: 10.1186/s13148-015-0089-x     Document Type: Article
Times cited : (77)

References (103)
  • 1
    • 27644546807 scopus 로고    scopus 로고
    • Brain metastases: Epidemiology and pathophysiology
    • Gavrilovic IT, Posner JB. Brain metastases: Epidemiology and pathophysiology. J Neuro-Oncol. 2005;75(1):5-14.
    • (2005) J Neuro-Oncol , vol.75 , Issue.1 , pp. 5-14
    • Gavrilovic, I.T.1    Posner, J.B.2
  • 2
    • 0036405461 scopus 로고    scopus 로고
    • Management of brain metastases
    • Soffietti R, Ruda R, Mutani R. Management of brain metastases. J Neurol. 2002;249(10):1357-69.
    • (2002) J Neurol , vol.249 , Issue.10 , pp. 1357-1369
    • Soffietti, R.1    Ruda, R.2    Mutani, R.3
  • 3
    • 34548241776 scopus 로고    scopus 로고
    • Central nervous system metastases in HER-2 positive metastatic breast cancer patients treated with trastuzumab: Incidence, survival, and risk factors
    • Gori S et al. Central nervous system metastases in HER-2 positive metastatic breast cancer patients treated with trastuzumab: Incidence, survival, and risk factors. Oncologist. 2007;12(7):766-73.
    • (2007) Oncologist , vol.12 , Issue.7 , pp. 766-773
    • Gori, S.1
  • 4
    • 33846550085 scopus 로고    scopus 로고
    • Late risk of relapse and mortality among postmenopausal women with estrogen responsive early breast cancer after 5 years of tamoxifen
    • Kennecke HF et al. Late risk of relapse and mortality among postmenopausal women with estrogen responsive early breast cancer after 5 years of tamoxifen. Ann Oncol. 2007;18(1):45-51.
    • (2007) Ann Oncol , vol.18 , Issue.1 , pp. 45-51
    • Kennecke, H.F.1
  • 5
    • 54449102442 scopus 로고    scopus 로고
    • Chemotherapy in breast cancer patients with brain metastases: Have new chemotherapic agents changed the clinical outcome?
    • Tosoni A, Franceschi E, Brandes AA. Chemotherapy in breast cancer patients with brain metastases: have new chemotherapic agents changed the clinical outcome? Crit Rev Oncol Hematol. 2008;68(3):212-21.
    • (2008) Crit Rev Oncol Hematol , vol.68 , Issue.3 , pp. 212-221
    • Tosoni, A.1    Franceschi, E.2    Brandes, A.A.3
  • 6
    • 26244462371 scopus 로고    scopus 로고
    • Breast cancer metastasis to the central nervous system
    • Weil RJ et al. Breast cancer metastasis to the central nervous system. Am J Pathol. 2005;167(4):913-20.
    • (2005) Am J Pathol , vol.167 , Issue.4 , pp. 913-920
    • Weil, R.J.1
  • 7
    • 55749103898 scopus 로고    scopus 로고
    • Brain metastases: Current management and new developments
    • Soffietti R, Ruda R, Trevisan E. Brain metastases: Current management and new developments. Curr Opin Oncol. 2008;20(6):676-84.
    • (2008) Curr Opin Oncol , vol.20 , Issue.6 , pp. 676-684
    • Soffietti, R.1    Ruda, R.2    Trevisan, E.3
  • 8
    • 79952100626 scopus 로고    scopus 로고
    • Management of cerebral metastasis: Evidence-based approach for surgery, stereotactic radiosurgery and radiotherapy
    • Jenkinson MD et al. Management of cerebral metastasis: Evidence-based approach for surgery, stereotactic radiosurgery and radiotherapy. Eur J Cancer. 2011;47(5):649-55.
    • (2011) Eur J Cancer , vol.47 , Issue.5 , pp. 649-655
    • Jenkinson, M.D.1
  • 9
    • 77952567992 scopus 로고    scopus 로고
    • Diagnosis-specific prognostic factors, indexes, and treatment outcomes for patients with newly diagnosed brain metastases: A multi-institutional analysis of 4,259 patients
    • Sperduto PW et al. Diagnosis-specific prognostic factors, indexes, and treatment outcomes for patients with newly diagnosed brain metastases: a multi-institutional analysis of 4,259 patients. Int J Radiat Oncol Biol Phys. 2010;77(3):655-61.
    • (2010) Int J Radiat Oncol Biol Phys , vol.77 , Issue.3 , pp. 655-661
    • Sperduto, P.W.1
  • 10
    • 3242805433 scopus 로고
    • The organ selectivity of experimentally induced metastases in rats
    • SUGARBAKER ED. The organ selectivity of experimentally induced metastases in rats. Cancer. 1952;5(3):606-12.
    • (1952) Cancer , vol.5 , Issue.3 , pp. 606-612
    • Sugarbaker, E.D.1
  • 12
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • TCGA. Comprehensive molecular portraits of human breast tumours. Nature. 2012;490(7418):61-70.
    • (2012) Nature , vol.490 , Issue.7418 , pp. 61-70
  • 13
    • 84861527388 scopus 로고    scopus 로고
    • The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
    • Curtis C et al. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature. 2012;486(7403):346-52.
    • (2012) Nature , vol.486 , Issue.7403 , pp. 346-352
    • Curtis, C.1
  • 14
    • 78650309082 scopus 로고    scopus 로고
    • Genomic Grade Index: An important tool for assessing breast cancer tumor grade and prognosis
    • Metzger FO, Ignatiadis M, Sotiriou C. Genomic Grade Index: an important tool for assessing breast cancer tumor grade and prognosis. Crit Rev Oncol Hematol. 2011;77(1):20-9.
    • (2011) Crit Rev Oncol Hematol , vol.77 , Issue.1 , pp. 20-29
    • Metzger, F.O.1    Ignatiadis, M.2    Sotiriou, C.3
  • 15
    • 34547785702 scopus 로고    scopus 로고
    • Brain metastases in patients with advanced breast cancer
    • Sanna G et al. Brain metastases in patients with advanced breast cancer. Anticancer Res. 2007;27(4C):2865-9.
    • (2007) Anticancer Res , vol.27 , Issue.4C , pp. 2865-2869
    • Sanna, G.1
  • 16
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van’t Veer LJ et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature. 2002;415(6871):530-6.
    • (2002) Nature , vol.415 , Issue.6871 , pp. 530-536
    • Van’T Veer, L.J.1
  • 17
    • 21244481753 scopus 로고    scopus 로고
    • Predictors of central nervous system metastasis in patients with metastatic breast cancer. A competing risk analysis of 579 patients treated with epirubicin-based chemotherapy
    • Ryberg M et al. Predictors of central nervous system metastasis in patients with metastatic breast cancer. A competing risk analysis of 579 patients treated with epirubicin-based chemotherapy. Breast Cancer Res Treat. 2005;91(3):217-25.
    • (2005) Breast Cancer Res Treat , vol.91 , Issue.3 , pp. 217-225
    • Ryberg, M.1
  • 18
    • 84890281328 scopus 로고    scopus 로고
    • Metastasis dormancy in estrogen receptor-positive breast cancer
    • Zhang XH et al. Metastasis dormancy in estrogen receptor-positive breast cancer. Clin Cancer Res. 2013;19(23):6389-97.
    • (2013) Clin Cancer Res , vol.19 , Issue.23 , pp. 6389-6397
    • Zhang, X.H.1
  • 19
    • 35548936833 scopus 로고    scopus 로고
    • Models, mechanisms and clinical evidence for cancer dormancy
    • Aguirre-Ghiso JA. Models, mechanisms and clinical evidence for cancer dormancy. Nat Rev Cancer. 2007;7(11):834-46.
    • (2007) Nat Rev Cancer , vol.7 , Issue.11 , pp. 834-846
    • Aguirre-Ghiso, J.A.1
  • 20
    • 84866464861 scopus 로고    scopus 로고
    • The natural history of hormone receptor-positive breast cancer
    • Lim E, Metzger-Filho O, Winer EP. The natural history of hormone receptor-positive breast cancer. Oncology (Williston Park). 2012;26(8):688-94. 696.
    • (2012) Oncology (Williston Park) , vol.26 , Issue.8 , pp. 688-694
    • Lim, E.1    Metzger-Filho, O.2    Winer, E.P.3
  • 21
    • 42649100970 scopus 로고    scopus 로고
    • Detection, clinical relevance and specific biological properties of disseminating tumour cells
    • Pantel K, Brakenhoff RH, Brandt B. Detection, clinical relevance and specific biological properties of disseminating tumour cells. Nat Rev Cancer. 2008;8(5):329-40.
    • (2008) Nat Rev Cancer , vol.8 , Issue.5 , pp. 329-340
    • Pantel, K.1    Brakenhoff, R.H.2    Brandt, B.3
  • 22
    • 0642337591 scopus 로고    scopus 로고
    • The systemic progression of human cancer: A focus on the individual disseminated cancer cell-the unit of selection
    • Klein CA. The systemic progression of human cancer: a focus on the individual disseminated cancer cell-the unit of selection. Adv Cancer Res. 2003;89:35-67.
    • (2003) Adv Cancer Res , vol.89 , pp. 35-67
    • Klein, C.A.1
  • 23
    • 84870745374 scopus 로고    scopus 로고
    • Epigenetic control of epithelial-to-mesenchymal transition and cancer metastasis
    • Wang Y, Shang Y. Epigenetic control of epithelial-to-mesenchymal transition and cancer metastasis. Exp Cell Res. 2013;319(2):160-9.
    • (2013) Exp Cell Res , vol.319 , Issue.2 , pp. 160-169
    • Wang, Y.1    Shang, Y.2
  • 24
    • 63049104211 scopus 로고    scopus 로고
    • Microenvironmental regulation of metastasis
    • Joyce JA, Pollard JW. Microenvironmental regulation of metastasis. Nat Rev Cancer. 2009;9(4):239-52.
    • (2009) Nat Rev Cancer , vol.9 , Issue.4 , pp. 239-252
    • Joyce, J.A.1    Pollard, J.W.2
  • 25
    • 0036675220 scopus 로고    scopus 로고
    • Metastasis to bone: Causes, consequences and therapeutic opportunities
    • Mundy GR. Metastasis to bone: Causes, consequences and therapeutic opportunities. Nat Rev Cancer. 2002;2(8):584-93.
    • (2002) Nat Rev Cancer , vol.2 , Issue.8 , pp. 584-593
    • Mundy, G.R.1
  • 26
    • 33846049299 scopus 로고    scopus 로고
    • NF-kappaB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF
    • Park BK et al. NF-kappaB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF. Nat Med. 2007;13(1):62-9.
    • (2007) Nat Med , vol.13 , Issue.1 , pp. 62-69
    • Park, B.K.1
  • 27
    • 77950536708 scopus 로고    scopus 로고
    • Identification of 5 novel genes methylated in breast and other epithelial cancers
    • Hill VK et al. Identification of 5 novel genes methylated in breast and other epithelial cancers. Mol Cancer. 2010;9:51.
    • (2010) Mol Cancer , vol.9 , pp. 51
    • Hill, V.K.1
  • 28
    • 0028096611 scopus 로고
    • High sensitivity mapping of methylated cytocines
    • Clark SJ et al. High sensitivity mapping of methylated cytocines. Nucleic Acid Research. 1994;22(15):2990-7.
    • (1994) Nucleic Acid Research , vol.22 , Issue.15 , pp. 2990-2997
    • Clark, S.J.1
  • 29
    • 79958045766 scopus 로고    scopus 로고
    • The biology of brain metastases-translation to new therapies
    • Eichler AF et al. The biology of brain metastases-translation to new therapies. Nat Rev Clin Oncol. 2011;8(6):344-56.
    • (2011) Nat Rev Clin Oncol , vol.8 , Issue.6 , pp. 344-356
    • Eichler, A.F.1
  • 30
    • 67650091620 scopus 로고    scopus 로고
    • Epigenetic DNA-(Cytosine-5-carbon) modifications: 5-aza-2′-deoxycytidine and DNA-demethylation
    • Patra SK, Bettuzzi S. Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2′-deoxycytidine and DNA-demethylation. Biochemistry (Mosc). 2009;74(6):613-9.
    • (2009) Biochemistry (Mosc) , vol.74 , Issue.6 , pp. 613-619
    • Patra, S.K.1    Bettuzzi, S.2
  • 31
    • 77950859659 scopus 로고    scopus 로고
    • Identification of candidate tumour suppressor genes frequently methylated in renal cell carcinoma
    • Morris MR et al. Identification of candidate tumour suppressor genes frequently methylated in renal cell carcinoma. Oncogene. 2010;29(14):2104-17.
    • (2010) Oncogene , vol.29 , Issue.14 , pp. 2104-2117
    • Morris, M.R.1
  • 32
    • 79953062931 scopus 로고    scopus 로고
    • Genome-wide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma
    • Morris MR et al. Genome-wide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma. Oncogene. 2011;30(12):1390-401.
    • (2011) Oncogene , vol.30 , Issue.12 , pp. 1390-1401
    • Morris, M.R.1
  • 33
    • 67650670767 scopus 로고    scopus 로고
    • PrognoScan: A new database for meta-analysis of the prognostic value of genes
    • Mizuno H et al. PrognoScan: a new database for meta-analysis of the prognostic value of genes. BMC Med Genomics. 2009;2:18.
    • (2009) BMC Med Genomics , vol.2 , pp. 18
    • Mizuno, H.1
  • 34
    • 0020343311 scopus 로고
    • Maximally selected chi square statistics
    • Miller R, Siegmund D. Maximally selected chi square statistics. Biometrics. 1982;38:1011-6.
    • (1982) Biometrics , vol.38 , pp. 1011-1016
    • Miller, R.1    Siegmund, D.2
  • 35
    • 19944422061 scopus 로고    scopus 로고
    • A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
    • Paik S et al. A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med. 2004;351(27):2817-26.
    • (2004) N Engl J Med , vol.351 , Issue.27 , pp. 2817-2826
    • Paik, S.1
  • 37
    • 84872659017 scopus 로고    scopus 로고
    • The methylation landscape of tumour metastasis
    • Cock-Rada A, Weitzman JB. The methylation landscape of tumour metastasis. Biol Cell. 2013;105(2):73-90.
    • (2013) Biol Cell , vol.105 , Issue.2 , pp. 73-90
    • Cock-Rada, A.1    Weitzman, J.B.2
  • 38
    • 84861576201 scopus 로고    scopus 로고
    • The landscape of cancer genes and mutational processes in breast cancer
    • Stephens PJ et al. The landscape of cancer genes and mutational processes in breast cancer. Nature. 2012;486(7403):400-4.
    • (2012) Nature , vol.486 , Issue.7403 , pp. 400-404
    • Stephens, P.J.1
  • 39
    • 84857509296 scopus 로고    scopus 로고
    • Deep time: The long and the short of adjuvant endocrine therapy for breast cancer
    • Burstein HJ, Griggs JJ. Deep time: the long and the short of adjuvant endocrine therapy for breast cancer. J Clin Oncol. 2012;30(7):684-6.
    • (2012) J Clin Oncol , vol.30 , Issue.7 , pp. 684-686
    • Burstein, H.J.1    Griggs, J.J.2
  • 40
    • 33751252276 scopus 로고    scopus 로고
    • Cancer metastasis: Building a framework
    • Gupta GP, Massague J. Cancer metastasis: building a framework. Cell. 2006;127(4):679-95.
    • (2006) Cell , vol.127 , Issue.4 , pp. 679-695
    • Gupta, G.P.1    Massague, J.2
  • 41
    • 0036674501 scopus 로고    scopus 로고
    • Dissemination and growth of cancer cells in metastatic sites
    • Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer. 2002;2(8):563-72.
    • (2002) Nat Rev Cancer , vol.2 , Issue.8 , pp. 563-572
    • Chambers, A.F.1    Groom, A.C.2    Macdonald, I.C.3
  • 42
    • 63049090100 scopus 로고    scopus 로고
    • Metastasis: From dissemination to organ-specific colonization
    • Nguyen DX, Bos PD, Massague J. Metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer. 2009;9(4):274-84.
    • (2009) Nat Rev Cancer , vol.9 , Issue.4 , pp. 274-284
    • Nguyen, D.X.1    Bos, P.D.2    Massague, J.3
  • 43
    • 23144461051 scopus 로고    scopus 로고
    • Genes that mediate breast cancer metastasis to lung
    • Minn AJ et al. Genes that mediate breast cancer metastasis to lung. Nature. 2005;436(7050):518-24.
    • (2005) Nature , vol.436 , Issue.7050 , pp. 518-524
    • Minn, A.J.1
  • 44
    • 0038488950 scopus 로고    scopus 로고
    • A multigenic program mediating breast cancer metastasis to bone
    • Kang Y et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell. 2003;3(6):537-49.
    • (2003) Cancer Cell , vol.3 , Issue.6 , pp. 537-549
    • Kang, Y.1
  • 45
    • 78049480691 scopus 로고    scopus 로고
    • GeneCards Version 3: The human gene integrator
    • Safran M et al. GeneCards Version 3: the human gene integrator. Database. 2010. doi:10.1093/database/baq020.
    • (2010) Database
    • Safran, M.1
  • 46
    • 0035077832 scopus 로고    scopus 로고
    • O-glycosylation of the mucin type
    • Hanisch FG. O-glycosylation of the mucin type. Biol Chem. 2001;382(2):143-9.
    • (2001) Biol Chem , vol.382 , Issue.2 , pp. 143-149
    • Hanisch, F.G.1
  • 47
    • 33744799438 scopus 로고    scopus 로고
    • Glycodynamics and functions
    • Brockhausen I. Mucin-type O-glycans in human colon and breast cancer
    • Brockhausen I. Mucin-type O-glycans in human colon and breast cancer: Glycodynamics and functions. EMBO Rep. 2006;7(6):599-604.
    • (2006) EMBO Rep , vol.7 , Issue.6 , pp. 599-604
  • 48
    • 0026495694 scopus 로고
    • Effects of differentiating agents on cell surface expression of the breast carcinoma-associated DF3-P epitope
    • Perey L, Hayes DF, Kufe D. Effects of differentiating agents on cell surface expression of the breast carcinoma-associated DF3-P epitope. Cancer Res. 1992;52(22):6365-70.
    • (1992) Cancer Res , vol.52 , Issue.22 , pp. 6365-6370
    • Perey, L.1    Hayes, D.F.2    Kufe, D.3
  • 49
    • 0025831282 scopus 로고
    • Prediction of prognosis in primary breast cancer by detection of a high molecular weight mucin-like antigen using monoclonal antibodies DF3, F36/22, and CU18: A Cancer and Leukemia Group B study
    • Hayes DF et al. Prediction of prognosis in primary breast cancer by detection of a high molecular weight mucin-like antigen using monoclonal antibodies DF3, F36/22, and CU18: a Cancer and Leukemia Group B study. J Clin Oncol. 1991;9(7):1113-23.
    • (1991) J Clin Oncol , vol.9 , Issue.7 , pp. 1113-1123
    • Hayes, D.F.1
  • 50
    • 34447517882 scopus 로고    scopus 로고
    • The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome of invasive ductal breast carcinoma
    • van der Vegt B et al. The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome of invasive ductal breast carcinoma. Histopathology. 2007;51(3):322-35.
    • (2007) Histopathology , vol.51 , Issue.3 , pp. 322-335
    • Van Der Vegt, B.1
  • 51
    • 34447548814 scopus 로고    scopus 로고
    • The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome in ‘pure’ ductal carcinoma in situ of the breast
    • de Roos MA et al. The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome in ‘pure’ ductal carcinoma in situ of the breast. Histopathology. 2007;51(2):227-38.
    • (2007) Histopathology , vol.51 , Issue.2 , pp. 227-238
    • De Roos, M.A.1
  • 52
    • 84875204974 scopus 로고    scopus 로고
    • Expression of underglycosylated MUC1 antigen in cancerous and adjacent normal breast tissues
    • Ghosh SK et al. Expression of underglycosylated MUC1 antigen in cancerous and adjacent normal breast tissues. Clin Breast Cancer. 2013;13(2):109-18.
    • (2013) Clin Breast Cancer , vol.13 , Issue.2 , pp. 109-118
    • Ghosh, S.K.1
  • 53
    • 84872021037 scopus 로고    scopus 로고
    • GALNT9 gene expression is a prognostic marker in neuroblastoma patients
    • Berois N et al. GALNT9 gene expression is a prognostic marker in neuroblastoma patients. Clin Chem. 2013;59(1):225-33.
    • (2013) Clin Chem , vol.59 , Issue.1 , pp. 225-233
    • Berois, N.1
  • 54
    • 84860381244 scopus 로고    scopus 로고
    • UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferases: Completion of the family tree
    • Raman J et al. UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases: completion of the family tree. Glycobiology. 2012;22(6):768-77.
    • (2012) Glycobiology , vol.22 , Issue.6 , pp. 768-777
    • Raman, J.1
  • 55
    • 84859012703 scopus 로고    scopus 로고
    • Characterization of ppGalNAc-T18, a member of the vertebratespecific Y subfamily of UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferases
    • Li X et al. Characterization of ppGalNAc-T18, a member of the vertebratespecific Y subfamily of UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases. Glycobiology. 2012;22(5):602-15.
    • (2012) Glycobiology , vol.22 , Issue.5 , pp. 602-615
    • Li, X.1
  • 56
    • 0037414798 scopus 로고    scopus 로고
    • Cloning and characterization of a new human UDP-N-acetylalpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen
    • Zhang Y et al. Cloning and characterization of a new human UDP-N-acetylalpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen. J Biol Chem. 2003;278(1):573-84.
    • (2003) J Biol Chem , vol.278 , Issue.1 , pp. 573-584
    • Zhang, Y.1
  • 57
    • 84908890637 scopus 로고    scopus 로고
    • Identification of 33 candidate oncogenes by screening for base-specific mutations
    • Tuupanen S et al. Identification of 33 candidate oncogenes by screening for base-specific mutations. Br J Cancer. 2014;111(8):1657-62.
    • (2014) Br J Cancer , vol.111 , Issue.8 , pp. 1657-1662
    • Tuupanen, S.1
  • 58
    • 84885074034 scopus 로고    scopus 로고
    • The somatic genomic landscape of glioblastoma
    • Brennan CW et al. The somatic genomic landscape of glioblastoma. Cell. 2013;155(2):462-77.
    • (2013) Cell , vol.155 , Issue.2 , pp. 462-477
    • Brennan, C.W.1
  • 59
    • 84905029258 scopus 로고    scopus 로고
    • Comprehensive molecular profiling of lung adenocarcinoma
    • Research CGA. N. Comprehensive molecular profiling of lung adenocarcinoma. Nature. 2014;511(7511):543-50.
    • (2014) Nature , vol.511 , Issue.7511 , pp. 543-550
    • Research, C.G.A.N.1
  • 60
    • 84866894408 scopus 로고    scopus 로고
    • Comprehensive genomic characterization of squamous cell lung cancers
    • Research CGA
    • Research CGA, N. Comprehensive genomic characterization of squamous cell lung cancers. Nature. 2012;489(7417):519-25.
    • (2012) Nature. , vol.489 , Issue.7417 , pp. 519-525
  • 61
    • 38549146003 scopus 로고    scopus 로고
    • Basonuclin regulates a subset of ribosomal RNA genes in HaCaT cells
    • Zhang S, Wang J, Tseng H. Basonuclin regulates a subset of ribosomal RNA genes in HaCaT cells. PLoS One. 2007;2(9), e902.
    • (2007) Plos One , vol.2 , Issue.9
    • Zhang, S.1    Wang, J.2    Tseng, H.3
  • 62
    • 33747882082 scopus 로고    scopus 로고
    • Search for basonuclin target genes
    • Wang J et al. Search for basonuclin target genes. Biochem Biophys Res Commun. 2006;348(4):1261-71.
    • (2006) Biochem Biophys Res Commun , vol.348 , Issue.4 , pp. 1261-1271
    • Wang, J.1
  • 63
    • 33745077971 scopus 로고    scopus 로고
    • Basonuclin: A novel mammalian maternal-effect gene
    • Ma J et al. Basonuclin: a novel mammalian maternal-effect gene. Development. 2006;133(10):2053-62.
    • (2006) Development , vol.133 , Issue.10 , pp. 2053-2062
    • Ma, J.1
  • 64
    • 33845926895 scopus 로고    scopus 로고
    • A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies
    • Shames DS et al. A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies. PLoS Med. 2006;3(12), e486.
    • (2006) Plos Med , vol.3 , Issue.12
    • Shames, D.S.1
  • 65
    • 84890276015 scopus 로고    scopus 로고
    • Novel methylation biomarker panel for the early detection of pancreatic cancer
    • Yi JM et al. Novel methylation biomarker panel for the early detection of pancreatic cancer. Clin Cancer Res. 2013;19(23):6544-55.
    • (2013) Clin Cancer Res , vol.19 , Issue.23 , pp. 6544-6555
    • Yi, J.M.1
  • 66
    • 84887609207 scopus 로고    scopus 로고
    • Identification of novel DNA-methylated genes that correlate with human prostate cancer and high-grade prostatic intraepithelial neoplasia
    • Devaney JM et al. Identification of novel DNA-methylated genes that correlate with human prostate cancer and high-grade prostatic intraepithelial neoplasia. Prostate Cancer Prostatic Dis. 2013;16(4):292-300.
    • (2013) Prostate Cancer Prostatic Dis , vol.16 , Issue.4 , pp. 292-300
    • Devaney, J.M.1
  • 67
    • 66449095254 scopus 로고    scopus 로고
    • Epigenetic analysis of childhood acute lymphoblastic leukemia
    • Dunwell TL et al. Epigenetic analysis of childhood acute lymphoblastic leukemia. Epigenetics. 2009;4(3):185-93.
    • (2009) Epigenetics , vol.4 , Issue.3 , pp. 185-193
    • Dunwell, T.L.1
  • 68
    • 84928292743 scopus 로고    scopus 로고
    • Basonuclin-1 modulates epithelial plasticity and TGF-beta1-induced loss of epithelial cell integrity
    • Feuerborn A et al. Basonuclin-1 modulates epithelial plasticity and TGF-beta1-induced loss of epithelial cell integrity. Oncogene. 2015;34(9):1185-95.
    • (2015) Oncogene , vol.34 , Issue.9 , pp. 1185-1195
    • Feuerborn, A.1
  • 69
    • 79959254447 scopus 로고    scopus 로고
    • Selection of brain metastasis-initiating breast cancer cells determined by growth on hard agar
    • Guo L et al. Selection of brain metastasis-initiating breast cancer cells determined by growth on hard agar. Am J Pathol. 2011;178(5):2357-66.
    • (2011) Am J Pathol , vol.178 , Issue.5 , pp. 2357-2366
    • Guo, L.1
  • 70
    • 80051548898 scopus 로고    scopus 로고
    • Exome sequencing identifies CCDC8 mutations in 3-M syndrome, suggesting that CCDC8 contributes in a pathway with CUL7 and OBSL1 to control human growth
    • Hanson D et al. Exome sequencing identifies CCDC8 mutations in 3-M syndrome, suggesting that CCDC8 contributes in a pathway with CUL7 and OBSL1 to control human growth. Am J Hum Genet. 2011;89(1):148-53.
    • (2011) Am J Hum Genet , vol.89 , Issue.1 , pp. 148-153
    • Hanson, D.1
  • 71
    • 27144498420 scopus 로고    scopus 로고
    • Identification of mutations in CUL7 in 3-M syndrome
    • Huber C et al. Identification of mutations in CUL7 in 3-M syndrome. Nat Genet. 2005;37(10):1119-24.
    • (2005) Nat Genet , vol.37 , Issue.10 , pp. 1119-1124
    • Huber, C.1
  • 72
    • 60749135834 scopus 로고    scopus 로고
    • A large-scale mutation search reveals genetic heterogeneity in 3M syndrome
    • Huber C et al. A large-scale mutation search reveals genetic heterogeneity in 3M syndrome. EJHG. 2009;17(3):395-400.
    • (2009) EJHG , vol.17 , Issue.3 , pp. 395-400
    • Huber, C.1
  • 73
    • 37249033121 scopus 로고    scopus 로고
    • Clinical, molecular and histopathological features of short stature syndrome with novel CUL7 mutation in Yakuts: New population isolate in Asia
    • Maksimova N et al. Clinical, molecular and histopathological features of short stature syndrome with novel CUL7 mutation in Yakuts: new population isolate in Asia. J Med Genet. 2007;44(12):772-8.
    • (2007) J Med Genet , vol.44 , Issue.12 , pp. 772-778
    • Maksimova, N.1
  • 75
    • 84901836016 scopus 로고    scopus 로고
    • The 3M complex maintains microtubule and genome integrity
    • Yan J et al. The 3M complex maintains microtubule and genome integrity. Mol Cell. 2014;54(5):791-804.
    • (2014) Mol Cell , vol.54 , Issue.5 , pp. 791-804
    • Yan, J.1
  • 76
    • 84901827031 scopus 로고    scopus 로고
    • CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity
    • Li Z et al. CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity. Mol Cell. 2014;54(5):805-19.
    • (2014) Mol Cell , vol.54 , Issue.5 , pp. 805-819
    • Li, Z.1
  • 77
    • 0034524084 scopus 로고    scopus 로고
    • The Structure and Function of Claudins, Cell Adhesion Molecules at Tight Junctions
    • Tsukita S, Furuse M. The Structure and Function of Claudins, Cell Adhesion Molecules at Tight Junctions. Ann N Y Acad Sci. 2000;915:129-35.
    • (2000) Ann N Y Acad Sci , vol.915 , pp. 129-135
    • Tsukita, S.1    Furuse, M.2
  • 78
    • 65449149031 scopus 로고    scopus 로고
    • Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia
    • Bragulla HH, Homberger DG. Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia. J Anat. 2009;214(4):516-59.
    • (2009) J Anat , vol.214 , Issue.4 , pp. 516-559
    • Bragulla, H.H.1    Homberger, D.G.2
  • 79
    • 76649103030 scopus 로고    scopus 로고
    • Mutations in the keratin 85 (KRT85/hHb5) gene underlie pure hair and nail ectodermal dysplasia
    • Shimomura Y et al. Mutations in the keratin 85 (KRT85/hHb5) gene underlie pure hair and nail ectodermal dysplasia. J Invest Dermatol. 2010;130(3):892-5.
    • (2010) J Invest Dermatol , vol.130 , Issue.3 , pp. 892-895
    • Shimomura, Y.1
  • 80
    • 34249723830 scopus 로고    scopus 로고
    • Structural and regulatory functions of keratins
    • Magin TM, Vijayaraj P, Leube RE. Structural and regulatory functions of keratins. Exp Cell Res. 2007;313(10):2021-32.
    • (2007) Exp Cell Res , vol.313 , Issue.10 , pp. 2021-2032
    • Magin, T.M.1    Vijayaraj, P.2    Leube, R.E.3
  • 81
    • 84894235175 scopus 로고    scopus 로고
    • MiR-127 regulates cell proliferation and senescence by targeting BCL6
    • Chen J et al. miR-127 regulates cell proliferation and senescence by targeting BCL6. PLoS One. 2013;8(11):e80266.
    • (2013) Plos One , vol.8 , Issue.11
    • Chen, J.1
  • 82
    • 68149178467 scopus 로고    scopus 로고
    • Down-regulated miR-9 and miR-433 in human gastric carcinoma
    • Luo H et al. Down-regulated miR-9 and miR-433 in human gastric carcinoma. J Exp Clin Cancer Res. 2009;28:82.
    • (2009) J Exp Clin Cancer Res , vol.28 , pp. 82
    • Luo, H.1
  • 84
    • 8344250878 scopus 로고    scopus 로고
    • Retroviral delivery of homeobox D3 gene induces cerebral angiogenesis in mice
    • Chen Y et al. Retroviral delivery of homeobox D3 gene induces cerebral angiogenesis in mice. J Cereb Blood Flow Metab. 2004;24(11):1280-7.
    • (2004) J Cereb Blood Flow Metab , vol.24 , Issue.11 , pp. 1280-1287
    • Chen, Y.1
  • 85
    • 84878535897 scopus 로고    scopus 로고
    • MiR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts
    • Pellegrino L et al. miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts. Nucleic Acids Res. 2013;41(10):5400-12.
    • (2013) Nucleic Acids Res , vol.41 , Issue.10 , pp. 5400-5412
    • Pellegrino, L.1
  • 86
    • 84877766516 scopus 로고    scopus 로고
    • Prooncogenic factors miR-23b and miR-27b are regulated by Her2/Neu, EGF, and TNF-alpha in breast cancer
    • Jin L et al. Prooncogenic factors miR-23b and miR-27b are regulated by Her2/Neu, EGF, and TNF-alpha in breast cancer. Cancer Res. 2013;73(9):2884-96.
    • (2013) Cancer Res , vol.73 , Issue.9 , pp. 2884-2896
    • Jin, L.1
  • 87
    • 84871222985 scopus 로고    scopus 로고
    • MiR-23b represses proto-oncogene Src kinase and functions as methylation-silenced tumor suppressor with diagnostic and prognostic significance in prostate cancer
    • Majid S et al. miR-23b represses proto-oncogene Src kinase and functions as methylation-silenced tumor suppressor with diagnostic and prognostic significance in prostate cancer. Cancer Res. 2012;72(24):6435-46.
    • (2012) Cancer Res , vol.72 , Issue.24 , pp. 6435-6446
    • Majid, S.1
  • 88
    • 84870021606 scopus 로고    scopus 로고
    • Inhibition of PTEN gene expression by oncogenic miR-23b-3p in renal cancer
    • Zaman MS et al. Inhibition of PTEN gene expression by oncogenic miR-23b-3p in renal cancer. PLoS One. 2012;7(11), e50203.
    • (2012) Plos One , vol.7 , Issue.11
    • Zaman, M.S.1
  • 89
    • 77952716929 scopus 로고    scopus 로고
    • HOXB13 promotes androgen independent growth of LNCaP prostate cancer cells by the activation of E2F signaling
    • Kim YR et al. HOXB13 promotes androgen independent growth of LNCaP prostate cancer cells by the activation of E2F signaling. Mol Cancer. 2010;9:124.
    • (2010) Mol Cancer , vol.9 , pp. 124
    • Kim, Y.R.1
  • 90
    • 77954086798 scopus 로고    scopus 로고
    • Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer
    • Muggerud AA et al. Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer. BCR. 2010;12(1):R3.
    • (2010) BCR , vol.12 , Issue.1 , pp. 3
    • Muggerud, A.A.1
  • 92
    • 46749115181 scopus 로고    scopus 로고
    • Met‐Related Receptor Tyrosine Kinase Ron in Tumor Growth and Metastasis
    • Wagh PK, Peace BE, Waltz SE. Met‐Related Receptor Tyrosine Kinase Ron in Tumor Growth and Metastasis. Adv Cancer Res. 2008;100:1-33.
    • (2008) Adv Cancer Res , vol.100 , pp. 1-33
    • Wagh, P.K.1    Peace, B.E.2    Waltz, S.E.3
  • 93
    • 0032191946 scopus 로고    scopus 로고
    • Characterization of Two Novel Protocadherins (PCDH8 and PCDH9) Localized on Human Chromosome 13 and Mouse Chromosome 14
    • Sabine Strehl KG, Qiu ML, Heather G, Lalande M. Characterization of Two Novel Protocadherins (PCDH8 and PCDH9) Localized on Human Chromosome 13 and Mouse Chromosome 14. Genomics. 1998;53:81-9.
    • (1998) Genomics , vol.53 , pp. 81-89
    • Sabine Strehl, K.G.1    Qiu, M.L.2    Heather, G.3    Lalande, M.4
  • 94
    • 0032127977 scopus 로고    scopus 로고
    • Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
    • Niwa H, Burdon T, Chambers I, Smith A. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev. 1998;12:2048-60.
    • (1998) Genes Dev , vol.12 , pp. 2048-2060
    • Niwa, H.1    Burdon, T.2    Chambers, I.3    Smith, A.4
  • 95
    • 0030935260 scopus 로고    scopus 로고
    • Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
    • Takeda K, Shi W, Tanaka T, Matsumoto M, Yoshida N, Kishimoto T, et al. Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Dev Biol. 1997;94:3801-4.
    • (1997) Dev Biol , vol.94 , pp. 3801-3804
    • Takeda, K.1    Shi, W.2    Tanaka, T.3    Matsumoto, M.4    Yoshida, N.5    Kishimoto, T.6
  • 96
    • 0034657958 scopus 로고    scopus 로고
    • Roles of STAT3 defined by tissue-specifc gene targeting
    • Akira S. Roles of STAT3 defined by tissue-specifc gene targeting. Oncogene. 2000;19(21):2607-11.
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2607-2611
    • Akira, S.1
  • 97
    • 33644879427 scopus 로고    scopus 로고
    • Bves, a member of the Popeye domain-containing gene family
    • Osler ME, Smith TK, Bader DM. Bves, a member of the Popeye domain-containing gene family. Dev Dyn. 2006;235(3):586-93.
    • (2006) Dev Dyn , vol.235 , Issue.3 , pp. 586-593
    • Osler, M.E.1    Smith, T.K.2    Bader, D.M.3
  • 98
    • 79954623906 scopus 로고    scopus 로고
    • Genome-wide DNA methylation profiling of CpG islands in breast cancer identifies novel genes associated with tumorigenicity
    • Hill VK et al. Genome-wide DNA methylation profiling of CpG islands in breast cancer identifies novel genes associated with tumorigenicity. Cancer Res. 2011;71(8):2988-99.
    • (2011) Cancer Res , vol.71 , Issue.8 , pp. 2988-2999
    • Hill, V.K.1
  • 99
    • 34548161177 scopus 로고    scopus 로고
    • Epigenetic silencing of claudin-6 promotes anchorage-independent growth of breast carcinoma cells
    • Osanai M et al. Epigenetic silencing of claudin-6 promotes anchorage-independent growth of breast carcinoma cells. Cancer Sci. 2007;98(10):1557-62.
    • (2007) Cancer Sci , vol.98 , Issue.10 , pp. 1557-1562
    • Osanai, M.1
  • 100
    • 23844537411 scopus 로고    scopus 로고
    • Homeobox D10 induces phenotypic reversion of breast tumor cells in a three-dimensional culture model
    • Carrio M et al. Homeobox D10 induces phenotypic reversion of breast tumor cells in a three-dimensional culture model. Cancer Res. 2005;65(16):7177-85.
    • (2005) Cancer Res , vol.65 , Issue.16 , pp. 7177-7185
    • Carrio, M.1
  • 101
    • 0034618602 scopus 로고    scopus 로고
    • Brain-speci¢c expression of a novel human UDP-GalNAc:Polypeptide N-acetylgalactosaminyltransferase (GalNAc-T9)
    • Shinya Toba MT, Morichika KTM, et al. Brain-speci¢c expression of a novel human UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T9). Biochim Biophys Acta. 2000;1493:264-8.
    • (2000) Biochim Biophys Acta , vol.1493 , pp. 264-268
    • Shinya Toba, M.T.1    Morichika, K.2
  • 102
    • 33745634864 scopus 로고    scopus 로고
    • Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer
    • Ai L et al. Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer. Carcinogenesis. 2006;27(7):1341-8.
    • (2006) Carcinogenesis , vol.27 , Issue.7 , pp. 1341-1348
    • Ai, L.1
  • 103
    • 68349139365 scopus 로고    scopus 로고
    • Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer
    • Veeck J et al. Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer. BMC Cancer. 2009;9:217.
    • (2009) BMC Cancer , vol.9 , pp. 217
    • Veeck, J.1


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