-
1
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L, Moorhead PS (1961) The serial cultivation of human diploid cell strains. Exp Cell Res 25: 585-621.
-
(1961)
Exp Cell Res
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
2
-
-
34548186667
-
Cellular senescence: When bad things happen to good cells
-
DOI 10.1038/nrm2233, PII NRM2233
-
Campisi J, d'Adda di Fagagna F (2007) Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol 8: 729-740. (Pubitemid 47312822)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.9
, pp. 729-740
-
-
Campisi, J.1
D'Adda, D.F.F.2
-
3
-
-
1842789989
-
Mechanisms of cellular senescence in human and mouse cells
-
DOI 10.1023/B:BGEN.0000017682.96395.10
-
Itahana K, Campisi J, Dimri GP (2004) Mechanisms of cellular senescence in human and mouse cells. Biogerontology 5: 1-10. (Pubitemid 38461023)
-
(2004)
Biogerontology
, vol.5
, Issue.1
, pp. 1-10
-
-
Itahana, K.1
Campisi, J.2
Dimri, G.P.3
-
4
-
-
84873638532
-
Aging, cellular senescence, and cancer
-
Campisi J (2013) Aging, cellular senescence, and cancer. Annu Rev Physiol 75: 685-705.
-
(2013)
Annu Rev Physiol
, vol.75
, pp. 685-705
-
-
Campisi, J.1
-
5
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
-
Campisi J (2005) Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120: 513-522.
-
(2005)
Cell
, vol.120
, pp. 513-522
-
-
Campisi, J.1
-
6
-
-
83855165805
-
MicroRNAs as a novel cellular senescence regulator
-
Liu FJ, Wen T, Liu L (2012) MicroRNAs as a novel cellular senescence regulator. Ageing Res Rev 11: 41-50.
-
(2012)
Ageing Res Rev
, vol.11
, pp. 41-50
-
-
Liu, F.J.1
Wen, T.2
Liu, L.3
-
7
-
-
84857079737
-
The microcosmos of cancer
-
Lujambio A, Lowe SW (2012) The microcosmos of cancer. Nature 482: 347-355.
-
(2012)
Nature
, vol.482
, pp. 347-355
-
-
Lujambio, A.1
Lowe, S.W.2
-
8
-
-
79956315291
-
MicroRegulators come of age in senescence
-
Gorospe M, Abdelmohsen K (2011) MicroRegulators come of age in senescence. Trends Genet 27: 233-241.
-
(2011)
Trends Genet
, vol.27
, pp. 233-241
-
-
Gorospe, M.1
Abdelmohsen, K.2
-
9
-
-
79959273231
-
Differential expression of oncogenic miRNAs in proliferating and senescent human fibroblasts
-
Wang M, Cheng Z, Tian T, Chen J, Dou F, et al. (2011) Differential expression of oncogenic miRNAs in proliferating and senescent human fibroblasts. Mol Cell Biochem 352: 271-279.
-
(2011)
Mol Cell Biochem
, vol.352
, pp. 271-279
-
-
Wang, M.1
Cheng, Z.2
Tian, T.3
Chen, J.4
Dou, F.5
-
10
-
-
84873707192
-
The microRNAs within the DLK1-DIO3 genomic region: Involvement in disease pathogenesis
-
Benetatos L, Hatzimichael E, Londin E, Vartholomatos G, Loher P, et al. (2013) The microRNAs within the DLK1-DIO3 genomic region: involvement in disease pathogenesis. Cell Mol Life Sci 70: 795-814.
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 795-814
-
-
Benetatos, L.1
Hatzimichael, E.2
Londin, E.3
Vartholomatos, G.4
Loher, P.5
-
11
-
-
54549105517
-
Transcriptional mechanism for the paired miR-433 and miR-127 genes by nuclear receptors SHP and ERRgamma
-
Song G, Wang L (2008) Transcriptional mechanism for the paired miR-433 and miR-127 genes by nuclear receptors SHP and ERRgamma. Nucleic Acids Res 36: 5727-5735.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 5727-5735
-
-
Song, G.1
Wang, L.2
-
12
-
-
71049116441
-
A conserved gene structure and expression regulation of miR-433 and miR-127 in mammals
-
Song G, Wang L (2009) A conserved gene structure and expression regulation of miR-433 and miR-127 in mammals. PLoS One 4: e7829.
-
(2009)
PLoS One
, vol.4
-
-
Song, G.1
Wang, L.2
-
13
-
-
55849085033
-
MiR-433 and miR-127 arise from independent overlapping primary transcripts encoded by the miR-433-127 locus
-
Song G, Wang L (2008) MiR-433 and miR-127 arise from independent overlapping primary transcripts encoded by the miR-433-127 locus. PLoS One 3: e3574.
-
(2008)
PLoS One
, vol.3
-
-
Song, G.1
Wang, L.2
-
14
-
-
33744805399
-
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
-
DOI 10.1016/j.ccr.2006.04.020, PII S1535610806001437
-
Saito Y, Liang G, Egger G, Friedman JM, Chuang JC, et al. (2006) Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9: 435-443. (Pubitemid 43832188)
-
(2006)
Cancer Cell
, vol.9
, Issue.6
, pp. 435-443
-
-
Saito, Y.1
Liang, G.2
Egger, G.3
Friedman, J.M.4
Chuang, J.C.5
Coetzee, G.A.6
Jones, P.A.7
-
15
-
-
66349096981
-
MicroRNA-127 modulates fetal lung development
-
Bhaskaran M, Wang Y, Zhang H, Weng T, Baviskar P, et al. (2009) MicroRNA-127 modulates fetal lung development. Physiol Genomics 37: 268-278.
-
(2009)
Physiol Genomics
, vol.37
, pp. 268-278
-
-
Bhaskaran, M.1
Wang, Y.2
Zhang, H.3
Weng, T.4
Baviskar, P.5
-
16
-
-
84862489258
-
Down-regulation of MiR-127 facilitates hepatocyte proliferation during rat liver regeneration
-
Pan C, Chen H, Wang L, Yang S, Fu H, et al. (2012) Down-regulation of MiR-127 facilitates hepatocyte proliferation during rat liver regeneration. PLoS One 7: e39151.
-
(2012)
PLoS One
, vol.7
-
-
Pan, C.1
Chen, H.2
Wang, L.3
Yang, S.4
Fu, H.5
-
17
-
-
0037087737
-
ARF-p53 signaling
-
DOI 10.1101/gad.929302
-
Shvarts A, Brummelkamp TR, Scheeren F, Koh E, Daley GQ, et al. (2002) A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling. Genes Dev 16: 681-686. (Pubitemid 34274037)
-
(2002)
Genes and Development
, vol.16
, Issue.6
, pp. 681-686
-
-
Shvarts, A.1
Brummelkamp, T.R.2
Scheeren, F.3
Koh, E.4
Daley, G.Q.5
Spits, H.6
Bernards, R.7
-
18
-
-
0035500487
-
Cellular senescence as a tumor-suppressor mechanism
-
Campisi J (2001) Cellular senescence as a tumor-suppressor mechanism. Trends Cell Biol 11: S27-31.
-
(2001)
Trends Cell Biol
, vol.11
-
-
Campisi, J.1
-
19
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
DOI 10.1038/nature05939, PII NATURE05939
-
He L, He X, Lim LP, de Stanchina E, Xuan Z, et al. (2007) A microRNA component of the p53 tumour suppressor network. Nature 447: 1130-1134. (Pubitemid 47014436)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
De Stanchina, E.4
Xuan, Z.5
Liang, Y.6
Xue, W.7
Zender, L.8
Magnus, J.9
Ridzon, D.10
Jackson, A.L.11
Linsley, P.S.12
Chen, C.13
Lowe, S.W.14
Cleary, M.A.15
Hannon, G.J.16
-
20
-
-
84859492189
-
Anti-oncogenic microRNA-203 induces senescence by targeting E2F3 protein in human melanoma cells
-
Noguchi S, Mori T, Otsuka Y, Yamada N, Yasui Y, et al. (2012) Anti-oncogenic microRNA-203 induces senescence by targeting E2F3 protein in human melanoma cells. J Biol Chem 287: 11769-11777.
-
(2012)
J Biol Chem
, vol.287
, pp. 11769-11777
-
-
Noguchi, S.1
Mori, T.2
Otsuka, Y.3
Yamada, N.4
Yasui, Y.5
-
21
-
-
79955509397
-
miR-22 represses cancer progression by inducing cellular senescence
-
Xu D, Takeshita F, Hino Y, Fukunaga S, Kudo Y, et al. (2011) miR-22 represses cancer progression by inducing cellular senescence. J Cell Biol 193: 409-424.
-
(2011)
J Cell Biol
, vol.193
, pp. 409-424
-
-
Xu, D.1
Takeshita, F.2
Hino, Y.3
Fukunaga, S.4
Kudo, Y.5
-
22
-
-
80055108071
-
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia
-
Hurtz C, Hatzi K, Cerchietti L, Braig M, Park E, et al. (2011) BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia. J Exp Med 208: 2163-2174.
-
(2011)
J Exp Med
, vol.208
, pp. 2163-2174
-
-
Hurtz, C.1
Hatzi, K.2
Cerchietti, L.3
Braig, M.4
Park, E.5
-
23
-
-
10344247666
-
The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells
-
DOI 10.1038/nature03147
-
Phan RT, Dalla-Favera R (2004) The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells. Nature 432: 635-639. (Pubitemid 39626271)
-
(2004)
Nature
, vol.432
, Issue.7017
, pp. 635-639
-
-
Phan, R.T.1
Dalla-Favera, R.2
-
24
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
DOI 10.1038/nature02118
-
d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, et al. (2003) A DNA damage checkpoint response in telomere-initiated senescence. Nature 426: 194-198. (Pubitemid 37442589)
-
(2003)
Nature
, vol.426
, Issue.6963
, pp. 194-198
-
-
D'Adda, D.F.F.1
Reaper, P.M.2
Clay-Farrace, L.3
Fiegler, H.4
Carr, P.5
Von Zglinicki, T.6
Saretzki, G.7
Carter, N.P.8
Jackson, S.P.9
-
25
-
-
0037086268
-
DNA damage is able to induce senescence in tumor cells in vitro and in vivo
-
te Poele RH, Okorokov AL, Jardine L, Cummings J, Joel SP (2002) DNA damage is able to induce senescence in tumor cells in vitro and in vivo. Cancer Res 62: 1876-1883. (Pubitemid 34408516)
-
(2002)
Cancer Research
, vol.62
, Issue.6
, pp. 1876-1883
-
-
Te, P.R.H.1
Okorokov, A.L.2
Jardine, L.3
Cummings, J.4
Joel, S.P.5
-
26
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
DOI 10.1038/nature03482
-
Bartkova J, Horejsi Z, Koed K, Kramer A, Tort F, et al. (2005) DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 434: 864-870. (Pubitemid 40558993)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 864-870
-
-
Bartkova, J.1
Horejsi, Z.2
Koed, K.3
Kramer, A.4
Tort, F.5
Zleger, K.6
Guldberg, P.7
Sehested, M.8
Nesland, J.M.9
Lukas, C.10
Orntoft, T.11
Lukas, J.12
Bartek, J.13
-
27
-
-
80051587553
-
MicroRNA-199a-3p is downregulated in human osteosarcoma and regulates cell proliferation and migration
-
Duan Z, Choy E, Harmon D, Liu X, Susa M, et al. (2011) MicroRNA-199a-3p is downregulated in human osteosarcoma and regulates cell proliferation and migration. Mol Cancer Ther 10: 1337-1345.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 1337-1345
-
-
Duan, Z.1
Choy, E.2
Harmon, D.3
Liu, X.4
Susa, M.5
-
28
-
-
9144248999
-
1 and hypoxia-inducible factor-1alpha (HIF-1alpha)
-
DOI 10.1038/sj.onc.1206995
-
Bos R, van Diest PJ, van der Groep P, Greijer AE, Hermsen MA, et al. (2003) Protein expression of B-cell lymphoma gene 6 (BCL-6) in invasive breast cancer is associated with cyclin D1 and hypoxia-inducible factor-1alpha (HIF-1alpha). Oncogene 22: 8948-8951. (Pubitemid 38021511)
-
(2003)
Oncogene
, vol.22
, Issue.55
, pp. 8948-8951
-
-
Bos, R.1
Van Diest, P.J.2
Van Der, G.P.3
Greijer, A.E.4
Hermsen, M.A.J.A.5
Heijnen, I.6
Meijer, G.A.7
Baak, J.P.A.8
Pinedo, H.M.9
Van Der, W.E.10
Shvarts, A.11
-
29
-
-
0042838295
-
BCL-6 is expressed in breast cancer and prevents mammary epithelial differentiation
-
DOI 10.1038/sj.onc.1206689
-
Logarajah S, Hunter P, Kraman M, Steele D, Lakhani S, et al. (2003) BCL-6 is expressed in breast cancer and prevents mammary epithelial differentiation. Oncogene 22: 5572-5578. (Pubitemid 37102692)
-
(2003)
Oncogene
, vol.22
, Issue.36
, pp. 5572-5578
-
-
Logarajah, S.1
Hunter, P.2
Kraman, M.3
Steele, D.4
Lakhani, S.5
Bobrow, L.6
Venkitaraman, A.7
Wagner, S.8
-
30
-
-
37349051019
-
Real-time PCR quantification of precursor and mature microRNA
-
DOI 10.1016/j.ymeth.2007.09.006, PII S1046202307001715, MicroRNAs: Part B
-
Schmittgen TD, Lee EJ, Jiang J, Sarkar A, Yang L, et al. (2008) Real-time PCR quantification of precursor and mature microRNA. Methods 44: 31-38. (Pubitemid 350297984)
-
(2008)
Methods
, vol.44
, Issue.1
, pp. 31-38
-
-
Schmittgen, T.D.1
Lee, E.J.2
Jiang, J.3
Sarkar, A.4
Yang, L.5
Elton, T.S.6
Chen, C.7
-
31
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri GP, Lee X, Basile G, Acosta M, Scott G, et al. (1995) A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A 92: 9363-9367.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
|