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Volumn 41, Issue 10, 2013, Pages 5400-5412

miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR; MICRORNA; MICRORNA 23B; TRANSCRIPTION FACTOR AP 1; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84878535897     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt245     Document Type: Article
Times cited : (112)

References (53)
  • 1
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall, A. (1998) Rho GTPases and the actin cytoskeleton. Science, 279, 509-514.
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 4
    • 0142027033 scopus 로고    scopus 로고
    • Cell surface receptors activate p21-activated kinase 1 via multiple Ras and PI3-kinasedependent pathways
    • Menard, R.E. and Mattingly, R.R. (2003) Cell surface receptors activate p21-activated kinase 1 via multiple Ras and PI3-kinasedependent pathways. Cell. Signal., 15, 1099-1109.
    • (2003) Cell. Signal. , vol.15 , pp. 1099-1109
    • Menard, R.E.1    Mattingly, R.R.2
  • 5
    • 0029828473 scopus 로고    scopus 로고
    • Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase
    • Tsakiridis, T., Taha, C., Grinstein, S. and Klip, A. (1996) Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase. J. Biol. Chem., 271, 19664-19667.
    • (1996) J. Biol. Chem. , vol.271 , pp. 19664-19667
    • Tsakiridis, T.1    Taha, C.2    Grinstein, S.3    Klip, A.4
  • 6
    • 0034671927 scopus 로고    scopus 로고
    • Vascular endothelial growth factor upregulation via p21-activated kinase-1 signaling regulates heregulinbeta1-mediated angiogenesis
    • Bagheri-Yarmand, R., Vadlamudi, R.K., Wang, R.A., Mendelsohn, J. and Kumar, R. (2000) Vascular endothelial growth factor upregulation via p21-activated kinase-1 signaling regulates heregulinbeta1-mediated angiogenesis. J. Biol. Chem., 275, 39451-39457.
    • (2000) J. Biol. Chem. , vol.275 , pp. 39451-39457
    • Bagheri-Yarmand, R.1    Vadlamudi, R.K.2    Wang, R.A.3    Mendelsohn, J.4    Kumar, R.5
  • 7
    • 44949176114 scopus 로고    scopus 로고
    • Pak1 and Pak2 mediate tumor cell invasion through distinct signaling mechanisms
    • ConiglioS, J., Zavarella, S. and Symons, M.H. (2008) Pak1 and Pak2 mediate tumor cell invasion through distinct signaling mechanisms. Mol. Cell. Biol., 28, 4162-4172.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 4162-4172
    • ConiglioS, J.1    Zavarella, S.2    Symons, M.H.3
  • 8
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel, D.P. (2009) MicroRNAs: Target recognition and regulatory functions. Cell, 136, 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 10
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • Ma, L., Teruya-Feldstein, J. and Weinberg, R.A. (2007) Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature, 449, 682-688.
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 16
    • 32144435296 scopus 로고    scopus 로고
    • Tumor cell migration in three dimensions
    • Hooper, S., Marshall, J.F. and Sahai, E. (2006) Tumor cell migration in three dimensions. Methods Enzymol., 406, 625-643.
    • (2006) Methods Enzymol. , vol.406 , pp. 625-643
    • Hooper, S.1    Marshall, J.F.2    Sahai, E.3
  • 17
    • 16544373284 scopus 로고    scopus 로고
    • Aberrant expression and function of TCF4 in the proliferation of hepatocellular carcinoma cell line BEL-7402
    • Zhao, D.H., Hong, J.J., Guo, S.Y., Yang, R.L., Yuan, J., Wen, C.Y., Zhou, K.Y. and Li, C.J. (2004) Aberrant expression and function of TCF4 in the proliferation of hepatocellular carcinoma cell line BEL-7402. Cell Res., 14, 74-80.
    • (2004) Cell Res. , vol.14 , pp. 74-80
    • Zhao, D.H.1    Hong, J.J.2    Guo, S.Y.3    Yang, R.L.4    Yuan, J.5    Wen, C.Y.6    Zhou, K.Y.7    Li, C.J.8
  • 18
    • 61849140657 scopus 로고    scopus 로고
    • Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis
    • Medjkane, S., Perez-Sanchez, C., Gaggioli, C., Sahai, E. and Treisman, R. (2009) Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis. Nat. Cell. Biol., 11, 257-268.
    • (2009) Nat. Cell. Biol. , vol.11 , pp. 257-268
    • Medjkane, S.1    Perez-Sanchez, C.2    Gaggioli, C.3    Sahai, E.4    Treisman, R.5
  • 19
    • 65549097632 scopus 로고    scopus 로고
    • MicroRNA-23b mediates urokinase and c-met downmodulation and a decreased migration of human hepatocellular carcinoma cells
    • Salvi, A., Sabelli, C., Moncini, S., Venturin, M., Arici, B., Riva, P., Portolani, N., Giulini, S.M., De Petro, G. and Barlati, S. (2009) MicroRNA-23b mediates urokinase and c-met downmodulation and a decreased migration of human hepatocellular carcinoma cells. FEBS J., 276, 2966-2982.
    • (2009) FEBS J , vol.276 , pp. 2966-2982
    • Salvi, A.1    Sabelli, C.2    Moncini, S.3    Venturin, M.4    Arici, B.5    Riva, P.6    Portolani, N.7    Giulini, S.M.8    De Petro, G.9    Barlati, S.10
  • 20
    • 82555193281 scopus 로고    scopus 로고
    • Genome wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis
    • Zhang, H., Hao, Y., Yang, J., Zhou, Y., Li, J., Yin, S., Sun, C., Ma, M., Huang, Y. and Xi, J.J. (2011) Genome - wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis. Nat. Commun., 2, 554.
    • (2011) Nat. Commun. , vol.2 , pp. 554
    • Zhang, H.1    Hao, Y.2    Yang, J.3    Zhou, Y.4    Li, J.5    Yin, S.6    Sun, C.7    Ma, M.8    Huang, Y.9    Xi, J.J.10
  • 21
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis, B.P., Burge, C.B. and Bartel, D.P. (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell, 120, 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 23
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da, W., Sherman, B.T. and Lempicki, R.A. (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc., 4, 44-57.
    • (2009) Nat. Protoc. , vol.4 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 24
    • 69249096109 scopus 로고    scopus 로고
    • Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-tomesenchymal transition in gemcitabine-resistant pancreatic cancer cells
    • Li, Y., VandenBoom, T.G. 2nd, Kong, D., Wang, Z., Ali, S., Philip, P.A. and Sarkar, F.H. (2009) Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-tomesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Cancer Res., 69, 6704-6712.
    • (2009) Cancer Res. , vol.69 , pp. 6704-6712
    • Li, Y.1    Vanden Boom II, T.G.2    Kong, D.3    Wang, Z.4    Ali, S.5    Philip, P.A.6    Sarkar, F.H.7
  • 25
    • 33749548025 scopus 로고    scopus 로고
    • Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells
    • Otani, T., Ichii, T., Aono, S. and Takeichi, M. (2006) Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells. J. Cell Biol., 175, 135-146.
    • (2006) J. Cell Biol. , vol.175 , pp. 135-146
    • Otani, T.1    Ichii, T.2    Aono, S.3    Takeichi, M.4
  • 26
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: Bidirectional, allosteric signaling machines
    • Hynes, R.O. (2002) Integrins: Bidirectional, allosteric signaling machines. Cell, 110, 673-687.
    • (2002) Cell , vol.110 , pp. 673-687
    • Hynes, R.O.1
  • 28
    • 58249128132 scopus 로고    scopus 로고
    • PAK signalling in neuronal physiology
    • Kreis, P. and Barnier, J.V. (2009) PAK signalling in neuronal physiology. Cell. Signal., 21, 384-393.
    • (2009) Cell. Signal. , vol.21 , pp. 384-393
    • Kreis, P.1    Barnier, J.V.2
  • 29
    • 0023759172 scopus 로고
    • Induction of proto-oncogene JUN/AP-1 by serum and TPA
    • Lamph, W.W., Wamsley, P., Sassone-Corsi, P. and Verma, I.M. (1988) Induction of proto-oncogene JUN/AP-1 by serum and TPA. Nature, 334, 629-631.
    • (1988) Nature , vol.334 , pp. 629-631
    • Lamph, W.W.1    Wamsley, P.2    Sassone-Corsi, P.3    Verma, I.M.4
  • 31
    • 0030981272 scopus 로고    scopus 로고
    • Expression pattern of glutamate decarboxylase (GAD) in the developing cortex of the embryonic chick brain
    • Lundgren, P., Johansson, L., Englund, C., Sellstrom, A. and Mattsson, M.O. (1997) Expression pattern of glutamate decarboxylase (GAD) in the developing cortex of the embryonic chick brain. Int. J. Dev. Neurosci., 15, 127-137.
    • (1997) Int. J. Dev. Neurosci. , vol.15 , pp. 127-137
    • Lundgren, P.1    Johansson, L.2    Englund, C.3    Sellstrom, A.4    Mattsson, M.O.5
  • 33
    • 70350464482 scopus 로고    scopus 로고
    • Hyperactivated NF-{kappa}B and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells
    • Ndlovu, N., Van Lint, C., Van Wesemael, K., Callebert, P., Chalbos, D., Haegeman, G. and Vanden Berghe, W. (2009) Hyperactivated NF-{kappa}B and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells. Mol. Cell. Biol., 29, 5488-5504.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 5488-5504
    • Ndlovu, N.1    Van Lint, C.2    Van Wesemael, K.3    Callebert, P.4    Chalbos, D.5    Haegeman, G.6    Vanden Berghe, W.7
  • 34
    • 0031916415 scopus 로고    scopus 로고
    • EGF-induced programmed cell death of human mammary carcinoma MDA-MB-468 cells is preceded by activation AP-1
    • Schaerli, P. and Jaggi, R. (1998) EGF-induced programmed cell death of human mammary carcinoma MDA-MB-468 cells is preceded by activation AP-1. Cell. Mol. Life Sci., 54, 129-138.
    • (1998) Cell. Mol. Life Sci. , vol.54 , pp. 129-138
    • Schaerli, P.1    Jaggi, R.2
  • 40
    • 84861389543 scopus 로고    scopus 로고
    • LIMK2 is a crucial regulator and effector of Aurora-A-kinase-mediated malignancy
    • Johnson, E.O., Chang, K.H., Ghosh, S., Venkatesh, C., Giger, K., Low, P.S. and Shah, K. (2012) LIMK2 is a crucial regulator and effector of Aurora-A-kinase-mediated malignancy. J. Cell Sci., 125, 1204-1216.
    • (2012) J. Cell Sci. , vol.125 , pp. 1204-1216
    • Johnson, E.O.1    Chang, K.H.2    Ghosh, S.3    Venkatesh, C.4    Giger, K.5    Low, P.S.6    Shah, K.7
  • 41
    • 14844310304 scopus 로고    scopus 로고
    • AlphaPIX associates with calpain 4 the small subunit of calpain, and has a dual role in integrin-mediated cell spreading
    • Rosenberger, G., Gal, A. and Kutsche, K. (2005) AlphaPIX associates with calpain 4, the small subunit of calpain, and has a dual role in integrin-mediated cell spreading. J. Biol. Chem., 280, 6879-6889.
    • (2005) J. Biol. Chem. , vol.280 , pp. 6879-6889
    • Rosenberger, G.1    Gal, A.2    Kutsche, K.3
  • 42
    • 84871903166 scopus 로고    scopus 로고
    • MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway
    • Xu, L., Wen, Z., Zhou, Y., Liu, Z., Li, Q., Fei, G., Luo, J. and Ren, T. (2013) MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway. Mol. Biol. Cell, 24, 42-55.
    • (2013) Mol. Biol. Cell , vol.24 , pp. 42-55
    • Xu, L.1    Wen, Z.2    Zhou, Y.3    Liu, Z.4    Li, Q.5    Fei, G.6    Luo, J.7    Ren, T.8
  • 43
    • 84862797610 scopus 로고    scopus 로고
    • Up-regulation of Anxa2 gene promotes proliferation and invasion of breast cancer MCF-7 cells
    • Wu, B., Zhang, F., Yu, M., Zhao, P., Ji, W., Zhang, H., Han, J. and Niu, R. (2012) Up-regulation of Anxa2 gene promotes proliferation and invasion of breast cancer MCF-7 cells. Cell Prolif., 45, 189-198.
    • (2012) Cell Prolif. , vol.45 , pp. 189-198
    • Wu, B.1    Zhang, F.2    Yu, M.3    Zhao, P.4    Ji, W.5    Zhang, H.6    Han, J.7    Niu, R.8
  • 46
    • 78549236549 scopus 로고    scopus 로고
    • Multimodal mass spectrometric imaging of small molecules reveals distinct spatiomolecular signatures in differentially metastatic breast tumor models
    • Amstalden van Hove, E.R. Blackwell, T.R., Klinkert, I., Eijkel, G.B., Heeren, R.M. and Glunde, K. Multimodal mass spectrometric imaging of small molecules reveals distinct spatiomolecular signatures in differentially metastatic breast tumor models. Cancer Res., 70, 9012-9021.
    • Cancer Res. , vol.70 , pp. 9012-9021
    • Amstalden Van Hove, E.R.1    Blackwell, T.R.2    Klinkert, I.3    Eijkel, G.B.4    Heeren, R.M.5    Glunde, K.6
  • 47
    • 0035651254 scopus 로고    scopus 로고
    • Rho-family GTPases in cadherin-mediated cell-cell adhesion
    • Fukata, M. and Kaibuchi, K. (2001) Rho-family GTPases in cadherin-mediated cell-cell adhesion. Nat. Rev. Mol. Cell Biol., 2, 887-897.
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 887-897
    • Fukata, M.1    Kaibuchi, K.2
  • 48
    • 77955466130 scopus 로고    scopus 로고
    • MiR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers
    • Vetter, G., Saumet, A., Moes, M., Vallar, L., Le Bechec, A., Laurini, C., Sabbah, M., Arar, K., Theillet, C., Lecellier, C.H. et al. (2010) miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers. Oncogene, 29, 4436-4448.
    • (2010) Oncogene , vol.29 , pp. 4436-4448
    • Vetter, G.1    Saumet, A.2    Moes, M.3    Vallar, L.4    Le Bechec, A.5    Laurini, C.6    Sabbah, M.7    Arar, K.8    Theillet, C.9    Lecellier, C.H.10
  • 49
    • 3242743242 scopus 로고    scopus 로고
    • Involvement of LMO7 in the association of two cell-cell adhesion molecules, nectin and E-cadherin, through afadin and alpha-actinin in epithelial cells
    • Ooshio, T., Irie, K., Morimoto, K., Fukuhara, A., Imai, T. and Takai, Y. (2004) Involvement of LMO7 in the association of two cell-cell adhesion molecules, nectin and E-cadherin, through afadin and alpha-actinin in epithelial cells. J. Biol. Chem., 279, 31365-31373.
    • (2004) J. Biol. Chem. , vol.279 , pp. 31365-31373
    • Ooshio, T.1    Irie, K.2    Morimoto, K.3    Fukuhara, A.4    Imai, T.5    Takai, Y.6
  • 50
    • 84855813448 scopus 로고    scopus 로고
    • A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells
    • Png, K.J., Halberg, N., Yoshida, M. and Tavazoie, S.F. (2012) A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells. Nature, 481, 190-194.
    • (2012) Nature , vol.481 , pp. 190-194
    • Png, K.J.1    Halberg, N.2    Yoshida, M.3    Tavazoie, S.F.4
  • 51
  • 52
    • 77956475436 scopus 로고    scopus 로고
    • Cooperative and individualistic functions of the microRNAs in the miR-23a-27a-24-2 cluster and its implication in human diseases
    • Chhabra, R., Dubey, R. and Saini, N. (2010) Cooperative and individualistic functions of the microRNAs in the miR-23a-27a-24-2 cluster and its implication in human diseases. Mol. Cancer, 9, 232.
    • (2010) Mol. Cancer , vol.9 , pp. 232
    • Chhabra, R.1    Dubey, R.2    Saini, N.3
  • 53
    • 14844365000 scopus 로고    scopus 로고
    • P21WAF1/CIP1 selectively controls the transcriptional activity of estrogen receptor alpha
    • Fritah, A., Saucier, C., Mester, J., Redeuilh, G. and Sabbah, M. (2005) p21WAF1/CIP1 selectively controls the transcriptional activity of estrogen receptor alpha. Mol. Cell. Biol., 25, 2419-2430.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 2419-2430
    • Fritah, A.1    Saucier, C.2    Mester, J.3    Redeuilh, G.4    Sabbah, M.5


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