Micro-adhesion rings surrounding TCR microclusters are essential for T cell activation

Journal of Experimental Medicine

Volumn 213, Issue 8, 2016, Pages 1609-1625

  Hashimoto Tane, Akiko ^a   Sakuma, Machie ^a   Ike, Hiroshi ^a,b   Yokosuka, Tadashi ^a,e   Kimura, Yayoi ^c   Ohara, Osamu ^a,d   Saito, Takashi ^a,b  

^a Institute of Physical and Chemical Research   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

^d KAZUSA DNA RESEARCH INSTITUTE   (Japan)

^e TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

F ACTIN; FOCAL ADHESION KINASE 2; INTEGRIN; LAT PROTEIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MYOSIN II; PAXILLIN; PROTEIN; PROTEIN SLP76; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; LAT PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE PROTEIN; PHOSPHOPROTEIN; PTK2B PROTEIN, MOUSE; PXN PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SLP-76 SIGNAL TRANSDUCING ADAPTOR PROTEINS;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; CONTROLLED STUDY; FOCAL ADHESION; IMMUNOLOGICAL SYNAPSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; ANIMAL; CYTOLOGY; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; PHYSIOLOGY; T LYMPHOCYTE; TRANSGENIC MOUSE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; FOCAL ADHESION KINASE 2; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; PAXILLIN; PHOSPHOPROTEINS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 84983002006     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20151088     Document Type: Article

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