Pyk2 is differentially regulated by β1 integrin- and CD28-mediated co-stimulation in human CD4+ T lymphocytes

European Journal of Immunology

Volumn 28, Issue 11, 1998, Pages 3867-3877

  Van Seventer, Gijs A ^a   Mullen, Maureen M ^a   Van Seventer, Jean Maguire ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

1 integrin; CD28; Pyk 2; Signaling; T cell

Indexed keywords

CD28 ANTIGEN; CD4 ANTIGEN; FOCAL ADHESION KINASE; INTEGRIN; INTERLEUKIN 2; MONOCLONAL ANTIBODY; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; CELL ADHESION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; T LYMPHOCYTE ACTIVATION;

ANTIGENS, CD28; ANTIGENS, CD29; ANTIGENS, CD3; CD4-POSITIVE T-LYMPHOCYTES; CELL ADHESION; CELL ADHESION MOLECULES; ENZYME ACTIVATION; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; JURKAT CELLS; LYMPHOCYTE ACTIVATION; MAP KINASE KINASE 4; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-TYROSINE KINASES; TYROSINE; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0031739792     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199811)28:11<3867::AID-IMMU3867>3.0.CO;2-K     Document Type: Article

References (43)

1. van Seventer, G. A., Shimizu, Y. and Shaw, S., Roles of multiple accessory molecules in T-cell activation. Curr. Opin. Immunol. 1991. 3: 294-303.
2. Springer, T. A., Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell 1994. 76: 301-314.
3. Shimizu, Y. and Shaw, S., Lymphocyte interactions with extracellular matrix. FASEB J. 1991. 5: 2292-2299.
4. + T cells by the interaction of VLA-4 and VLA-5 with fibronectin or VLA-6 with laminin. J. Immunol. 1990. 145: 59-67.
5. + T cell activation via the CS1 alternatively spliced domain of fibronectin. J. Exp. Med. 1990. 172: 1185-1192.
6. Davis, L. S., Oppenheimer-Marks, N., Bednarczyk, J. L., McIntyre, B. W. and Lipsky, P. E., Fibronectin promotes proliferation of naive and memory T cells by signalling through both VLA-4 and VLA-5 integrin molecules. J. Immunol. 1990. 145: 785-793.
7. van Seventer, G. A., Newman, W., Shimizu, Y., Nutman, T. B., Tanaka, Y., Morgan, K. J., Gopal, T. V., Ennis, E., O'Sullivan, D., Grey, H. and Shaw, S., Analysis of T-cell stimulation by superantigen plus major histocompatibility complex class II molecules or by CD3 monoclonal antibody: costimulation by purified adhesion ligands VCAM-1, ICAM-1 but not ELAM-1. J. Exp. Med. 1991. 174: 901-913.
8. + T lymphocytes. Proc. Natl. Acad. Sci. USA 1991. 88: 6403-6407.
9. Burkly, L. C., Jakubowski, A., Newman, B. M., Rosa, M. D., Chi-Rosso, G. and Lobb, R. R., Signaling by vascular cell adhesion molecule-1 (VCAM-1) through VLA-4 promotes CD3-dependent T cell proliferation. Eur. J. Immunol. 1991. 21: 2871-2875.
10. Yamada, A., Nikaido, T., Nojima, Y., Schlossman, S. F. and Morimoto, C., Activation of human CD4 T lymphocytes. Interaction of fibronectin with VLA-5 receptor on CD4 cells induces the AP-1 transcription factor. J. Immunol. 1991. 146: 53-56.
11. Sato, T., Tachibana, K., Nojima, Y., D'Aviro, N. and Morimoto, C., Role of the VLA-4 molecule in T cell costimulation. Identification of the tyrosine phosphorylation pattern induced by the ligation of VLA-4. J. Immunol. 1995. 155: 2938-2947.
12. Dedhar, S. and Hannigan, G. E., Integrin cytoplasmic interactions and bidirectional transmembrane signalling. Curr. Opin. Cell Biol. 1996. 8: 657-669.
13. 1 integrin-dependent tyrosine phosphorylation of focal adhesion kinase in human T cells. J. Exp. Med. 1995. 182: 2079-2090.
14. 2-integrin LFA-1 signaling through phospholipase Cγ1 activation. Proc. Natl. Acad. Sci. USA 1993. 90: 7099-7103.
15. ++ levels. J. Immunol. 1992. 149: 3872-3880.
16. Hanks, S. K. and Polte, T. R., Signaling through focal adhesion kinase. Bioessays 1997. 19: 137-145.
17. Parsons, J. T. and Parsons, S. J., Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways. Curr. Opin. Cell Biol. 1997. 9: 187-192.
18. Parsons, J. T., Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins. Curr. Opin. Cell Biol. 1996. 8: 146-152.
19. Lev, S., Moreno, H., Martinez, R., Canoll, P., Peles, E., Musacchio, J. M., Plowman, G. D., Rudy, B. and Schlessinger, J., Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions. Nature 1995. 376: 737-745.
20. Sasaki, H., Nagura, K., Ishino, M., Tobioka, H., Kotani, K. and Sasaki, T., Cloning and characterization of cell adhesion kinase beta, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily. J. Biol. Chem. 1995. 270: 21206-21219.
21. Avraham, S., London, R., Fu, Y., Ota, S., Hiregowdara, D., Li, J., Jiang, S., Pasztor, L. M., White, R. A., Groopman, J. E. et al., Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain. J. Biol. Chem. 1995. 270: 27742-27751.
22. Berg, N. N. and Ostergaard, H. L., T cell receptor engagement induces tyrosine phosphorylation of FAK and Pyk2 and their association with Lck. J. Immunol. 1997. 159: 1753-1757.
23. Ganju, R. K., Hatch, W. C., Avraham, H., Ona, M. A., Druker, B., Avraham, S. and Groopman, J. E., RAFTK, a novel member of the focal adhesion kinase family, is phosphorylated and associates with signaling molecules upon activation of mature T lymphocytes. J. Exp. Med. 1997. 185: 1055-1063.
24. Qian, D., Lev, S., van Oers, N. S, Dikic, I., Schlessinger, J. and Weiss, A., Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling. J. Exp. Med. 1997. 185: 1253-1259.
25. Ma, E. A., Lou, O., Berg, N. N. and Ostergaard, H. L., Cytotoxic T lymphocytes express a β3 integrin which can induce phosphorylation of focal adhesion kinase and the related PYK2. Eur. J. Immunol. 1997. 27: 329-335.
26. Tokiwa, G., Dikic, I., Lev, S. and Schlessinger, J., Activation of Pyk2 by stress signals and coupling with JNK signaling pathway. Science 1996. 273: 792-794.
27. Dikic, I., Tokiwa, G., Lev, S., Courtneidge, S. A. and Schlessinger, J., A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation. Nature 1996. 383: 547-550.
28. Baldari, C. T., Macchia, G. and Telford, J. L., Interleukin-2 promoter activation in T-cells expressing activated Ha-ras. J. Biol. Chem. 1992. 267: 4289-4291.
29. Rayter, S. I., Woodrow, M., Lucas, S. C., Cantrell, D. A. and Downward, J., p21ras mediates control of IL-2 gene promoter function in T cell activation. EMBO 1992. 11: 4549-4556.
30. Genot, E., Cleverley, S., Henning, S. and Cantrell, D. A., Multiple p21ras effector pathways regulate nuclear factor of activated T cells. EMBO 1996. 15: 3923-2933.
31. + T cells. Science 1996. 271: 1272-1276.
32. Altevogt, P., Hubbe, M., Ruppert, M., Lohr, J., von Hoegen, P., Sammar, M., Andrew, D. P., McEvoy, L., Humphries, M. J. and Butcher, E. C., The α4 integrin chain is a ligand for α4β7 and α4β1. J. Exp. Med. 1995. 182: 345-355.
33. Makgoba, M. W., Sanders, M. E., Luce, G. E. G., Dustin, M. L., Springer, T. A., Clark, E. A., Mannoni, P. and Shaw, S., ICAM-1 a ligand for LFA-1-dependent adhesion of B, T and myeloid cells. Nature 1988. 331: 86-88.
34. Shimizu, Y., van Seventer, G. A., Morgan, K. J. and Shaw, S., Regulated expression and function of three VLA (β1) integrin receptors on T cells. Nature 1990. 345: 250-253.
35. Tanaka, Y., Adams, D. H., Hubscher, S., Hirano, H., Siebenlist, U. and Shaw, S., T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-1β. Nature 1993. 361: 79-82.
36. Stewart, M. and Hogg, N., Regulation of leukocyte integrin function: affinity vs. avidity. J. Cell. Biochem. 1996. 61: 554-561.
37. Arroyo, A. G., Garcia-Pardo, A. and Sánchez-Madrid, F., A high affinity conformational state on VLA integrin heterodimers induced by an anti-β1 chain monoclonal antibody. J. Biol. Chem. 1993. 268: 9863-9868.
38. Faull, R. J., Kovach, N. L., Harlan, J. M. and Ginsberg, M. H., Stimulation of Integrin-mediated adhesion of T lymphocytes and monocytes: two mechanisms with divergent biological consequences. J. Exp. Med. 1994. 179: 1307-1316.
39. Astier, A., Avraham, H., Manie, S. N., Groopman, J., Canty, T., Avraham, S. and Freedman, A. S., The related adhesion focal tyrosine kinase is tyrosine-phosphorylated after betal -integrin stimulation in B cells and binds to p130cas. J. Biol. Chem. 1997. 272: 228-232.
40. Gismondi, A., Bisogno, L., Mainiero, F., Palmieri, G., Piccoli, M., Frati, L. and Santoni, A., Proline-rich tyrosine kinase-2 activation by β1 integrin fibronectin receptor cross-linking and association with paxillin in human natural killer cells. J. Immunol. 1997. 159: 4729-4736.
41. Damle, N. K., Klussman, K., Leytze, G., Ochs, H. D., Aruffo, A., Linsley, P. S. and Ledbetter, J. A., Costimulation via vascular cell adhesion molecule-1 induces in T cells increased responsiveness to the CD28 counter-receptor B7. Cell. Immunol. 1993. 148: 144-156.
42. Kuhlman, P., Moy, V. T., Lollo, B. A. and Brian, A. A., The accessory function of murine ICAM-1 in T lymphocyte activation: contributions of adhesion and coactivation. J. Immunol. 1991. 146: 1773-1782.
43. Horgan, K. J. and Shaw, S. in Coligan, J. E., Kruisbeek, A. M., Margulies, D. H., Shevach, E. M. and Strober, W. (Eds.), 1991. Current Protocols in Immunology, Wiley Interscience, New York, pages 7.4.1-7.4.6.