Increased immunoendocrine cells in intestinal mucosa of postinfectious irritable bowel syndrome patients 3 years after acute shigella infection - An observation in a small case control study

Yonsei Medical Journal

Volumn 51, Issue 1, 2010, Pages 45-51

  Kim, Hee Sun ^a   Lim, Jung Hyun ^a   Park, Hyojin ^a   Lee, Sang In ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

Enterochromaffin cell; Macrophage; Mast cell; Post infectious irritable bowel syndrome; T lymphocyte

Indexed keywords

CALGRANULIN; PEPTIDE YY; SEROTONIN;

ADULT; ARTICLE; BACTERIAL INFECTION; CASE CONTROL STUDY; CD3+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; COLON BIOPSY; COLONOSCOPY; CONTROLLED STUDY; DESCENDING COLON; DIARRHEA; ENTERITIS; ENTEROCHROMAFFIN CELL; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOLOGY; INTESTINE MUCOSA; IRRITABLE COLON; LAMINA PROPRIA; MACROPHAGE; MALE; MAST CELL; MUCOSA INFLAMMATION; OBSERVATIONAL STUDY; RECTUM BIOPSY; SHIGELLA; SHIGELLOSIS; SIGMOID; STOMACH EPITHELIUM;

ADULT; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CASE-CONTROL STUDIES; CD8-POSITIVE T-LYMPHOCYTES; COLON, DESCENDING; COLON, SIGMOID; COLONOSCOPY; DYSENTERY, BACILLARY; ENTEROCHROMAFFIN CELLS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; IRRITABLE BOWEL SYNDROME; MACROPHAGES; MALE; MAST CELLS; PEPTIDE YY; RECTUM; SEROTONIN;

EID: 75749115210     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.2010.51.1.45     Document Type: Article

References (39)

1. Gwee KA, Leong YL, Graham C, McKendrick MW, Collins SM, Walters SJ, et al. The role of psychological and biological factors in postinfective gut dysfunction. Gut 1999;44:400-6.
2. Dunlop SP, Jenkins D, Neal KR, Spiller RC. Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS. Gastroenterology 2003;125:1651-9.
3. Gwee KA, Graham JC, McKendrick MW, Collins SM, Marshall JS, Walters SJ, et al. Psychometric scores and persistence of irritable bowel after infectious diarrhoea. Lancet 1996;347:150-3.
4. McKendrick MW, Read NW. Irritable bowel syndrome-post salmonella infection. J Infect 1994;29:1-3.
5. Neal KR, Barker L, Spiller RC. Prognosis in post-infective irritable bowel syndrome: a six-year follow-up study. Gut 2002;51:410-3.
6. Neak KR, Hebden J, Spiller R. Prevalence of gastrointestinal symptoms six months after bacterial gastroenteritis and risk factors for development of the irritable bowel syndrome: postal survey of patients. BMJ 1997;314:779-82.
7. Rodríguez LA, Ruigómez A. Increased risk of irritable bowel syndrome after bacterial gastroenteritis: cohort study. BMJ 1999;318:565-6.
8. Hiatt RB, Katz J. Mast cells in inflammatory conditions of the gastrointestinal tract. Am J Gastroenterol 1962;37:541-5.
9. Weston AP, Biddle WL, Bhatia PS, Miner PB, Jr. Terminal ileal mucosal mast cells in irritable bowel syndrome. Dig Dis Sci 1993;38:1590-5.
10. O'Sullivan M, Clayton N, Breslin NP, Harman I, Bountra C, Mc-Laren A, et al. Increased mast cells in the irritable bowel syndrome. Neurogastroenterol Motil 2000;12:449-57.
11. Barbara G, Stanghellini V, De Giorgio R, Cremon C, Cottrell GS, Santini D, et al. Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome. Gastroenterology 2004;126:693-702.
12. Park CH, Joo YE, Choi SK, Rew JS, Kim SJ, Lee MC. Activated mast cells infiltrate in close proximity to enteric nerves in diarrheapredominant irritable bowel syndrome. J Korean Med Sci 2003;18:204-10.
13. Chadwick VS, Chen W, Shu D, Paulus B, Bethwaite P, Tie A, et al. Activation of the mucosal immune system in irritable bowel syndrome. Gastoenterology 2002;122:1778-83.
14. Kim HS, Kim MS, Ji SW, Park H. The development of irritable bowel syndrome after Shigella infection: 3 year follow-up study. Korean J Gastroenterol 2006;47:300-5.
15. Pardi DS, Ramnath VR, Loftus EV Jr, Tremaine WJ, Sandborn WJ. Lymphocytic colitis: clinical features, treatment, and outcomes. Am J Gastroenterol 2002;97:2829-33.
16. Veress B, Löfberg R, Bergman L. Microscopic colitis syndrome. Gut 1995;36:880-6.
17. Limsui D, Pardi DS, Camilleri M, Loftus EV Jr, Kammer PP, Tremaine WJ, et al. Symptomatic overlap between irritable bowel syndrome and microscopic colitis. Inflamm Bowel Dis 2007;13:175-81.
18. Ji S, Park H, Lee D, Song YK, Choi JP, Lee SI. Post-infectious irritable bowel syndrome in patients with Shigella infection. J Gastroenterol Hepatol 2005;20:381-6.
19. Berkes J, Viswanathan VK, Savkovic SD, Hecht G. Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation. Gut 2003;52:439-51.
20. Kucharzik T, Maaser C, Lügering A, Kagnoff M, Mayer L, Targan S, et al. Recent understanding of IBD pathogenesis: implications for future therapies. Inflamm Bowel Dis 2006;12:1068-83.
21. Tack J, Demedts I, Dehondt G, Caenepeel P, Fischler B, Zandecki M, et al. Clinical and pathophysiological characteristics of acute-onset functional dyspepsia. Gastroenterology 2002;122:1738-47.
22. Spiller RC. Postinfectious irritable bowel syndrome. Gastroenterology 2003;124:1662-71.
23. Bardhan PK, Salam MA, Molla AM. Gastric emptying of liquid in children suffering from acute rotaviral gastroenteritis. Gut 1992;33:26-9.
24. Mayer EA, Gebhart GF. Basic and clinical aspects of visceral hyperalgesia. Gastroenterology 1994;107:271-93.
25. Spiller RC, Jenkins D, Thornley JP, Hebden JM, Wright T, Skinner M, et al. Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome. Gut 2000;47:804-11.
26. Dunlop SP, Jenkins DJ, Spiller RC. Distictive clinical, psychological, and histological features of postinfective irritable bowel syndrome. Am J Gastroenterol 2003;98:1578-83.
27. Kim DY, Camilleri M. Serotonin: a mediator of the brain-gut connection. Am J Gastroenterol 2000;95:2698-709.
28. Tonini M. 5-Hydroxytryptamine effects in the gut: the 3,4, and 7 receptors. Neurogastroenterol Motil 2005;17:637-42.
29. Imamura M. Effects of surgical manipulation of the intestine on peptide YY and its physiology. Peptides 2002;23:403-7.
30. Imamura M, Nakajima H, Mikami Y, Yamauchi H. Morphological and immunohistochemical changes in intestinal mucosa and PYY release following total colectomy with ileal pouch-anal anastomosis in dogs. Dig Dis Sci 1999;44:1000-7.
31. Kong W, McConaloque K, Khitin LM, Hollenberg MD, Payan DG, Böhm SK, et al. Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2. Proc Natl Acad Sci U S A 1997;94:8884-9.
32. Li Y, Yio XY, Mayer L. Human intestinal epithelial cell-induced CD8+ T cell activation is mediated through CD8 and the activation of CD8-associated p56lck. J Exp Med 1995;182:1079-88.
33. Bjerke K, Halstensen TS, Jahnsen F, Pulford K, Brandtzaeg P. Distribution of macrophages and granulocytes expressing L1 protein(calprotectin) in human Peyer's patches compared with normal ileal lamina propria and mesenteric lymph nodes. Gut 1993;34:1357-63.
34. Rugtveit J, Brandtzaeg P, Halstensen TS, Fausa O, Scott H. Increased macrophage subset in inflammatory bowel disease: apparent recruitment from peripheral blood monocytes. Gut 1994;35:669-74.
35. Zhang X, Mosser DM. Macrophage activation by endogenous danger signals. J Pathol 2008;214:161-78.
36. Hausmann M, Bataille F, Spoettl T, Schreiter K, Falk W, Schoelmerich J, et al. Physiological role of macrophage inflammatory protein-3alpha induction during maturation of intestinal macrophages. J Immunol 2005;175:1389-98.
37. Motomura Y, Ghia JE, Wang H, Akiho H, El-Sharkawy RT, Collins M, et al. Enterochromaffin cell and 5-hydroxytryptamine responses to the same infectious agent differ in Th1 and Th2 dominant environments. Gut 2008;57:475-81.
38. Törnblom H, Lindberg G, Nyberg B, Veress B. Full-thickness biopsy of the jejunum reveals inflammation and enteric neuropathy in irritable bowel syndrome. Gastroenterology 2002;123:1972-9.
39. Chadwick VS, Chen W, Shu D, Paulus B, Bethwait P, Tie A, et al. Activation of the mucosal immune system in irritable bowel syndrome. Gastroenterology 2002;122:1778-83.