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Volumn 67, Issue 3, 2016, Pages 411-421

Melatonin metabolite, N1-acetyl-N1-formyl-5-methoxykynuramine (AFMK), attenuates acute pancreatitis in the rat: In vivo and in vitro studies

Author keywords

Acute pancreatitis; Antioxidant; Apoptosis; Lipid peroxidation; Melatonin; N1 acetyl N2 formyl 5 methoxykynuramine; Tumor necrosis factor alpha

Indexed keywords

4 HYDROXYNONENAL; AMYLASE; CASPASE 3; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; MELATONIN; MELATONIN DERIVATIVE; N1 ACETYL N2 FORMYL 5 METHOXYKYNURAMINE; PROTEIN BAX; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 4-HYDROXY-2-NONENAL; ALDEHYDE; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; BAX PROTEIN, RAT; CASP3 PROTEIN, RAT; KYNURAMINE; N-ACETYL-N-FORMYL-5-METHOXYKYNURENAMINE; TUMOR NECROSIS FACTOR;

EID: 84982992706     PISSN: 08675910     EISSN: 18991505     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (18)

References (58)
  • 1
    • 84955139419 scopus 로고    scopus 로고
    • Aethiology and outcomes of acute pancreatitis: A retrospective cohort study
    • Nesvaderani M, Eslick GD, Vaag D, Faraj S, Cox MR. Epidemiology, aethiology and outcomes of acute pancreatitis: A retrospective cohort study. Int J Surg 2015; 23: 68-74.
    • (2015) Int J Surg , vol.23 , pp. 68-74
    • Nesvaderani, M.1    Eslick, G.D.2    Vaag, D.3    Faraj, S.4    Epidemiology, C.5
  • 3
    • 84881369802 scopus 로고    scopus 로고
    • Prevalence and progression of acute pancreatitis in the swietokrzyskie voivodeship population
    • Gluszek S, Koziel D. Prevalence and progression of acute pancreatitis in the swietokrzyskie voivodeship population. Pol Przegl Chir 2012; 84: 618-625.
    • (2012) Pol Przegl Chir , vol.84 , pp. 618-625
    • Gluszek, S.1    Koziel, D.2
  • 5
    • 80054821679 scopus 로고    scopus 로고
    • Distribution, function and physiological role of melatonin in the lower gut
    • Chen CQ, Fichna J, Bashashati M, Li YY, Storr M. Distribution, function and physiological role of melatonin in the lower gut. World J Gastroenterol 2011; 17: 3888-3898.
    • (2011) World J Gastroenterol , vol.17 , pp. 3888-3898
    • Chen, C.Q.1    Fichna, J.2    Bashashati, M.3    Li, Y.Y.4    Storr, M.5
  • 6
    • 84905089096 scopus 로고    scopus 로고
    • Extrapineal melatonin: Sources, regulation and potential functions
    • Acuna-Castroviejo D, Escames G, Venegas C, et al. Extrapineal melatonin: sources, regulation and potential functions. Cell Mol Life Sci 2014; 71: 2997-3025.
    • (2014) Cell Mol Life Sci , vol.71 , pp. 2997-3025
    • Acuna-Castroviejo, D.1    Escames, G.2    Venegas, C.3
  • 7
    • 12244263456 scopus 로고    scopus 로고
    • Protective effect of melatonin and its precursor L-tryptophan on acute pancreatitis induced by caerulein overstimulation or ischemia/reperfusion
    • Jaworek J, Leja-Szpak A, Bonior J, et al. Protective effect of melatonin and its precursor L-tryptophan on acute pancreatitis induced by caerulein overstimulation or ischemia/reperfusion. J Pineal Res 2003; 34: 40-52.
    • (2003) J Pineal Res , vol.34 , pp. 40-52
    • Jaworek, J.1    Leja-Szpak, A.2    Bonior, J.3
  • 8
    • 84876510338 scopus 로고    scopus 로고
    • Protective effect of melatonin on acute pancreatitis
    • Jaworek J, Szklarczyk J, Jaworek AK, et al. Protective effect of melatonin on acute pancreatitis. Int J Inflam 2012; 2012: 173675. doi: 10.1155/2012/173675.
    • (2012) Int J Inflam
    • Jaworek, J.1    Szklarczyk, J.2    Jaworek, A.K.3
  • 10
    • 33644760772 scopus 로고    scopus 로고
    • Effect of melatonin on the severity of L-arginine-induced experimental pancreatitis in rats
    • Szabolcs A, Reiter RJ, Letoha T. Effect of melatonin on the severity of L-arginine-induced experimental pancreatitis in rats. World J.Gastroenterol 2006; 14; 12: 251-258.
    • (2006) World J.Gastroenterol , vol.14 , Issue.12 , pp. 251-258
    • Szabolcs, A.1    Reiter, R.J.2    Letoha, T.3
  • 11
    • 38149134547 scopus 로고    scopus 로고
    • Melatonin as modulator of pancreatic enzyme secretion and pancreatoprotector
    • Jaworek, J, Nawrot-Por¹bka K, Leja-Szpak, et al. Melatonin as modulator of pancreatic enzyme secretion and pancreatoprotector. J Physiol Pharmacol 2007; 58: 65-80.
    • (2007) J Physiol Pharmacol , vol.58 , pp. 65-80
    • Jaworek, J.1
  • 12
    • 77957827874 scopus 로고    scopus 로고
    • Melatonin signaling and cell protection function
    • Luchetti F, Canonico B, Betti M, et al. Melatonin signaling and cell protection function. FASEB J 2010; 24: 3603-3624.
    • (2010) FASEB J , vol.24 , pp. 3603-3624
    • Luchetti, F.1    Canonico, B.2    Betti, M.3
  • 13
    • 84906278663 scopus 로고    scopus 로고
    • The role of melatonin in the pancreatic protection: Could melatonin be used in the treatment of acute pancreatitis?
    • Jaworek J, Leja-Szpak A, Kot M, et al. The role of melatonin in the pancreatic protection: could melatonin be used in the treatment of acute pancreatitis? Curr Pharm Des 2014; 20: 4834-4840.
    • (2014) Curr Pharm Des , vol.20 , pp. 4834-4840
    • Jaworek, J.1    Leja-Szpak, A.2    Kot, M.3
  • 14
    • 84925835510 scopus 로고    scopus 로고
    • Melatonin: A well-documented antioxidant with conditional pro-oxidant actions
    • Zhang HM, Zhang Y. Melatonin: a well-documented antioxidant with conditional pro-oxidant actions. J Pineal Res 2014; 57: 131-146.
    • (2014) J Pineal Res , vol.57 , pp. 131-146
    • Zhang, H.M.1    Zhang, Y.2
  • 15
    • 84919667055 scopus 로고    scopus 로고
    • Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: A physiochemical analysis
    • Galano A, Medina ME, Tan DX, Reiter RJ. Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: a physiochemical analysis. J Pineal Res 2015; 58: 107-116.
    • (2015) J Pineal Res , vol.58 , pp. 107-116
    • Galano, A.1    Medina, M.E.2    Tan, D.X.3    Reiter, R.J.4
  • 16
    • 1642562820 scopus 로고    scopus 로고
    • Regulation of antioxidant enzymes: A significant role for melatonin
    • Rodriguez C, Mayo JC, Sainz RM, et al. Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res 2004; 36: 1-9.
    • (2004) J Pineal Res , vol.36 , pp. 1-9
    • Rodriguez, C.1    Mayo, J.C.2    Sainz, R.M.3
  • 17
    • 84867825011 scopus 로고    scopus 로고
    • Melatonin attenuates acute pancreatitis-associated lung injury in rats by modulating interleukin 22
    • Huai JP, Sun XC, Chen MJ, et al. Melatonin attenuates acute pancreatitis-associated lung injury in rats by modulating interleukin 22. World J Gastroenterol 2012; 18: 5122-5128.
    • (2012) World J Gastroenterol , vol.18 , pp. 5122-5128
    • Huai, J.P.1    Sun, X.C.2    Chen, M.J.3
  • 18
    • 77950343003 scopus 로고    scopus 로고
    • Melatonin modulates the severity of taurocholate-induced acute pancreatitis
    • Gulben K, Ozdemir H, Berberoglu U, et al. Melatonin modulates the severity of taurocholate-induced acute pancreatitis. Dig Dis Sci 2010; 55: 941-946.
    • (2010) Dig Dis Sci , vol.55 , pp. 941-946
    • Gulben, K.1    Ozdemir, H.2    Berberoglu, U.3
  • 19
    • 84875381309 scopus 로고    scopus 로고
    • Melatonin is involved in the apoptosis and necrosis of pancreatic cancer cell line via modulating of Bcl-2/Bax balance
    • Xu C, Wu A, Zhu H, et al. Melatonin is involved in the apoptosis and necrosis of pancreatic cancer cell line via modulating of Bcl-2/Bax balance. Biomed Pharmacother 2013; 67: 133-139.
    • (2013) Biomed Pharmacother , vol.67 , pp. 133-139
    • Xu, C.1    Wu, A.2    Zhu, H.3
  • 20
    • 84926509470 scopus 로고    scopus 로고
    • Melatonin induced apoptosis of colorectal cancer cells through HDAC4 nuclear import mediated by CaMKII inactivation
    • Wei JY, Li MW, Zhou LL, Lu QN, He W. Melatonin induced apoptosis of colorectal cancer cells through HDAC4 nuclear import mediated by CaMKII inactivation. J Pineal Res 2015; 58: 429-438.
    • (2015) J Pineal Res , vol.58 , pp. 429-438
    • Wei, J.Y.1    Li, M.W.2    Zhou, L.L.3    Lu, Q.N.4    He, W.5
  • 21
    • 84921671445 scopus 로고    scopus 로고
    • Melatonin induces apoptosis in cholangiocarcinomacell lines by activating the reactive oxygen species-mediated mitochondrial pathway
    • Laothong U, Hiraku Y, Oikawa S, Intuyod K, Murata M, Pinlaor S. Melatonin induces apoptosis in cholangiocarcinomacell lines by activating the reactive oxygen species-mediated mitochondrial pathway. Oncol Rep 2015; 33: 1443-1449.
    • (2015) Oncol Rep , vol.33 , pp. 1443-1449
    • Laothong, U.1    Hiraku, Y.2    Oikawa, S.3    Intuyod, K.4    Murata, M.5    Pinlaor, S.6
  • 23
    • 84922783044 scopus 로고    scopus 로고
    • Effect of percutaneous catheter drainage on pancreatic injury in rats with severe acute pancreatitis induced by sodium taurocholate
    • Chen GY, Dai RW, Luo H, et al. Effect of percutaneous catheter drainage on pancreatic injury in rats with severe acute pancreatitis induced by sodium taurocholate. Pancreatology 2015; 15: 71-77.
    • (2015) Pancreatology , vol.15 , pp. 71-77
    • Chen, G.Y.1    Dai, R.W.2    Luo, H.3
  • 24
    • 79958157501 scopus 로고    scopus 로고
    • Reactive oxygen species induced by bile acid induce apoptosis and protect against necrosis in pancreatic acinar cells
    • Booth DM, Murphy JA, Mukherjee R, et al. Reactive oxygen species induced by bile acid induce apoptosis and protect against necrosis in pancreatic acinar cells. Gastroenterology 2011; 140: 2116-2125.
    • (2011) Gastroenterology , vol.140 , pp. 2116-2125
    • Booth, D.M.1    Murphy, J.A.2    Mukherjee, R.3
  • 25
    • 68249129060 scopus 로고    scopus 로고
    • Kynuramines, metabolites of melatonin and other indoles: The resurrection of an almost forgotten class of biogenic amines
    • Harderland R, Tan DX, Reiter RJ. Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines. J Pineal Res 2009; 47: 109-126.
    • (2009) J Pineal Res , vol.47 , pp. 109-126
    • Harderland, R.1    Tan, D.X.2    Reiter, R.J.3
  • 26
    • 84949117036 scopus 로고    scopus 로고
    • Melatonin reduces lipid peroxidation and membrane fluidity
    • Reiter RJ, Tan DX, Galano A. Melatonin reduces lipid peroxidation and membrane fluidity. Front Physiol 2014; 5: 377.
    • (2014) Front Physiol , vol.5 , pp. 377
    • Reiter, R.J.1    Tan, D.X.2    Galano, A.3
  • 27
    • 33845536018 scopus 로고    scopus 로고
    • One molecule, many derivatives: A never-ending interaction of melatonin with reactive oxygen and nitrogen species
    • Tan DX, Manchester LC, Terron MP, Flores LJ, Reiter JR. One molecule, many derivatives: A never-ending interaction of melatonin with reactive oxygen and nitrogen species. J Pineal Res 2007; 42: 28-42.
    • (2007) J Pineal Res , vol.42 , pp. 28-42
    • Tan, D.X.1    Manchester, L.C.2    Terron, M.P.3    Flores, L.J.4    Reiter, J.R.5
  • 28
    • 84873413184 scopus 로고    scopus 로고
    • Indoleamine 2,3 dioxygenase in intestinal disease
    • Ciorba MA. Indoleamine 2,3 dioxygenase in intestinal disease. Curr Opin Gastroenterol 2013; 29: 146-152.
    • (2013) Curr Opin Gastroenterol , vol.29 , pp. 146-152
    • Ciorba, M.A.1
  • 29
    • 34249812687 scopus 로고    scopus 로고
    • Novel rhythms of N1-acetyl-N2-formyl-5-methoxykynuramine and its precursor melatonin in water hyacinth: Importance for phytoremediation
    • Tan DX, Manchester LC, Dimascio P, Martinez GR, Prado FM, Reiter RJ. Novel rhythms of N1-acetyl-N2-formyl-5-methoxykynuramine and its precursor melatonin in water hyacinth: importance for phytoremediation. FASEB J 2007; 21: 1724-1729.
    • (2007) FASEB J , vol.21 , pp. 1724-1729
    • Tan, D.X.1    Manchester, L.C.2    Dimascio, P.3    Martinez, G.R.4    Prado, F.M.5    Reiter, R.J.6
  • 30
    • 84874949228 scopus 로고    scopus 로고
    • On the free radical scavenging activities of melatonin metabolites; AFMK and AMK
    • Galano A, Tan DX, Reiter JR. On the free radical scavenging activities of melatonin metabolites; AFMK and AMK. J Pineal Res 2013; 54: 245-257.
    • (2013) J Pineal Res , vol.54 , pp. 245-257
    • Galano, A.1    Tan, D.X.2    Reiter, J.R.3
  • 31
    • 0032728487 scopus 로고    scopus 로고
    • Melatonin reduces lipid peroxidation and tissue edema in cerulein-induced acute pancreatitis in rats
    • Qi W, Tan DX, Reiter RJ, et al. Melatonin reduces lipid peroxidation and tissue edema in cerulein-induced acute pancreatitis in rats. Dig Dis Sci 1999; 44: 2257-2262.
    • (1999) Dig Dis Sci , vol.44 , pp. 2257-2262
    • Qi, W.1    Tan, D.X.2    Reiter, R.J.3
  • 32
    • 84928584203 scopus 로고    scopus 로고
    • Effect of melatonin on the oxidative damage and pancreatic antioxidant defenses in cerulein-induced acute pancreatitis in rats
    • Carrasco C, Rodriguez AB, Pariente JA. Effect of melatonin on the oxidative damage and pancreatic antioxidant defenses in cerulein-induced acute pancreatitis in rats. Hepatobiliary Pancreat Dis Int 2014; 13: 442-446.
    • (2014) Hepatobiliary Pancreat Dis Int , vol.13 , pp. 442-446
    • Carrasco, C.1    Rodriguez, A.B.2    Pariente, J.A.3
  • 33
    • 18444367676 scopus 로고    scopus 로고
    • Leptin protects the pancreas from damage induced by caerulein overstimulation by modulating cytokine production
    • Jaworek J, Bonior J, Pierzchalski P, et al. Leptin protects the pancreas from damage induced by caerulein overstimulation by modulating cytokine production. Pancreatology 2002; 2: 89-99.
    • (2002) Pancreatology , vol.2 , pp. 89-99
    • Jaworek, J.1    Bonior, J.2    Pierzchalski, P.3
  • 34
    • 84908399006 scopus 로고    scopus 로고
    • Tomaszewska R. Bilateral vagotomy attenuates the severity of secretagogue-induced acute pancreatitis in the rat
    • Szklarczyk J, Jaworek J, Czech U, Bonior, Kot M, Tomaszewska R. Bilateral vagotomy attenuates the severity of secretagogue-induced acute pancreatitis in the rat. Adv Med Sci 2014; 59: 172-177.
    • (2014) Adv Med Sci , vol.59 , pp. 172-177
    • Szklarczyk, J.1    Jaworek, J.2    Czech, U.3    Bonior, K.M.4
  • 36
    • 84946481377 scopus 로고    scopus 로고
    • Melatonin: An ancient molecule that makes oxygen metabolically tolerable
    • Manchester LC, Coto-Montes A, Boga JA, et al. Melatonin: an ancient molecule that makes oxygen metabolically tolerable. J Pineal Res 2015; 59: 403-419.
    • (2015) J Pineal Res , vol.59 , pp. 403-419
    • Manchester, L.C.1    Coto-Montes, A.2    Boga, J.A.3
  • 37
    • 84896890679 scopus 로고    scopus 로고
    • Effects of treatment with melatonin and tryptophan on liver enzymes, parameters of fat metabolism and plasma levels of cytokines in patients with non-alcoholic fatty liver disease-14 months follow up
    • Celinski K, Konturek PC, Slomka M, et al. Effects of treatment with melatonin and tryptophan on liver enzymes, parameters of fat metabolism and plasma levels of cytokines in patients with non-alcoholic fatty liver disease-14 months follow up. J Physiol Pharmacol 2014: 65: 75-82.
    • (2014) J Physiol Pharmacol , vol.65 , pp. 75-82
    • Celinski, K.1    Konturek, P.C.2    Slomka, M.3
  • 38
    • 84940035522 scopus 로고    scopus 로고
    • Alternative methods for feline fertility control: Use of melatonin to suppress reproduction
    • Kutzler MA. Alternative methods for feline fertility control: use of melatonin to suppress reproduction. J Feline Med Surg 2015; 17: 753-757.
    • (2015) J Feline Med Surg , vol.17 , pp. 753-757
    • Kutzler, M.A.1
  • 39
    • 84920008391 scopus 로고    scopus 로고
    • The influence of melatonin receptor antagonists, luzindole and 4-phenyl-2-propionamidotetralin (4-P-PDOT) on melatonindependent vasopressin and adrenocorticotropic hormone (ACTH) release from the rat hypothalamo-hypophyseal system. In vitro and in vivo studies
    • Juszczak M, Roszczyk M, Kowalczyk E, Stepniak B. The influence of melatonin receptor antagonists, luzindole and 4-phenyl-2-propionamidotetralin (4-P-PDOT) on melatonindependent vasopressin and adrenocorticotropic hormone (ACTH) release from the rat hypothalamo-hypophyseal system. In vitro and in vivo studies. J Physiol Pharmacol 2014; 65: 777-784.
    • (2014) J Physiol Pharmacol , vol.65 , pp. 777-784
    • Juszczak, M.1    Roszczyk, M.2    Kowalczyk, E.3    Stepniak, B.4
  • 40
    • 84904507080 scopus 로고    scopus 로고
    • Melatonin and its metabolites ameliorate ultraviolet B-induced damage in human epidermal keratinocytes
    • Janjetovic Z, Nahmias ZP, Hanna S, et al. Melatonin and its metabolites ameliorate ultraviolet B-induced damage in human epidermal keratinocytes. J Pineal Res 2014; 57: 90-102.
    • (2014) J Pineal Res , vol.57 , pp. 90-102
    • Janjetovic, Z.1    Nahmias, Z.P.2    Hanna, S.3
  • 41
    • 79960356607 scopus 로고    scopus 로고
    • Melatonin treatment restores the mitochondrial function in Alzheimer's mice: A mitochondrial protective role of melatonin membrane receptor signaling
    • Dragicevic N, Copes N, O'Neal-Moffitt G, et al. Melatonin treatment restores the mitochondrial function in Alzheimer's mice: a mitochondrial protective role of melatonin membrane receptor signaling. J Pineal Res 2011; 51: 75-86.
    • (2011) J Pineal Res , vol.51 , pp. 75-86
    • Dragicevic, N.1    Copes, N.2    O'neal-Moffitt, G.3
  • 42
    • 84879654262 scopus 로고    scopus 로고
    • Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells
    • Kim TK, Kleszczynski K, Janjetovic Z, et al. Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells. FASEB J 2013; 27: 2742-2755.
    • (2013) FASEB J , vol.27 , pp. 2742-2755
    • Kim, T.K.1    Kleszczynski, K.2    Janjetovic, Z.3
  • 43
    • 34147201601 scopus 로고    scopus 로고
    • AFMK, a melatonin metabolite attenuates x-ray-induced oxidative damage to DNA, proteins and lipids in mice
    • Manda K, Ueno M, Anzai K. AFMK, a melatonin metabolite attenuates x-ray-induced oxidative damage to DNA, proteins and lipids in mice. J Pineal Res 2007; 42: 386-393.
    • (2007) J Pineal Res , vol.42 , pp. 386-393
    • Manda, K.1    Ueno, M.2    Anzai, K.3
  • 44
    • 53749104127 scopus 로고    scopus 로고
    • Space radiation-induced inhibition of neurogenesis in the hippocampal dentate gyrus and memory impairment in mice: Ameliorative potential of the melatonin metabolite, AFMK
    • Manda K, Ueno M, Anzai K. Space radiation-induced inhibition of neurogenesis in the hippocampal dentate gyrus and memory impairment in mice: ameliorative potential of the melatonin metabolite, AFMK. J Pineal Res 2008; 45: 430-438.
    • (2008) J Pineal Res , vol.45 , pp. 430-438
    • Manda, K.1    Ueno, M.2    Anzai, K.3
  • 45
    • 0035487508 scopus 로고    scopus 로고
    • N1-acetyl-N1- formyl-5-methoxy-kynuramine, a biogenic amine and melatonin metabolite, functions as a potent antioxidant
    • Tan DX, Manchester LC, Burkhardt S, et al. N1-acetyl-N1- formyl-5-methoxy-kynuramine, a biogenic amine and melatonin metabolite, functions as a potent antioxidant. FASEB J 2001; 15: 2294-2296.
    • (2001) FASEB J , vol.15 , pp. 2294-2296
    • Tan, D.X.1    Manchester, L.C.2    Burkhardt, S.3
  • 46
    • 57149130854 scopus 로고    scopus 로고
    • The melatonin metabolite N1- acetyl-N1-formyl-5-methoxy- kynuramine is a potent singlet oxygen scavenger
    • Schaefer M, Hardeland R. The melatonin metabolite N1- acetyl-N1-formyl-5-methoxy- kynuramine is a potent singlet oxygen scavenger. J Pineal Res 2009; 46: 49-52.
    • (2009) J Pineal Res , vol.46 , pp. 49-52
    • Schaefer, M.1    Hardeland, R.2
  • 48
    • 84940784003 scopus 로고    scopus 로고
    • Protective effect of melatonin against thioacetamide-induced liver fibrosis in rats
    • Czechowska G, Celinski K, Korolczyk A, et al. Protective effect of melatonin against thioacetamide-induced liver fibrosis in rats. J Physiol Pharmacol 2015; 66: 567-579.
    • (2015) J Physiol Pharmacol , vol.66 , pp. 567-579
    • Czechowska, G.1    Celinski, K.2    Korolczyk, A.3
  • 49
    • 33644907794 scopus 로고    scopus 로고
    • Melatonin reduces pancreatic prostaglandins production and protects against caerulein-induced pancreatitis
    • Chen HM, Chen JC, Ng CJ, Chiu DF, Chen MF. Melatonin reduces pancreatic prostaglandins production and protects against caerulein-induced pancreatitis. J Pineal Res 2006; 40: 34-39.
    • (2006) J Pineal Res , vol.40 , pp. 34-39
    • Chen, H.M.1    Chen, J.C.2    Ng, C.J.3    Chiu, D.F.4    Chen, M.F.5
  • 50
    • 77955159826 scopus 로고    scopus 로고
    • Melatonin promotes angiogenesis during protection and healing of indomethacin-induced gastric ulcer: Role of matrix metalloproteinase-2
    • Ganguly K, Sharma AV, Reiter RJ, Swamakar S. Melatonin promotes angiogenesis during protection and healing of indomethacin-induced gastric ulcer: role of matrix metalloproteinase-2. J Pineal Res 2010; 49: 130-140.
    • (2010) J Pineal Res , vol.49 , pp. 130-140
    • Ganguly, K.1    Sharma, A.V.2    Reiter, R.J.3    Swamakar, S.4
  • 51
    • 77749310344 scopus 로고    scopus 로고
    • Melatonin ameliorates cerulein-induced pancreatitis by the modulation of nuclear erythroid 2-related factor 2 and nuclear factor-kappaB in rats
    • Jung KH, Hong SW, Zheng HM, et al. Melatonin ameliorates cerulein-induced pancreatitis by the modulation of nuclear erythroid 2-related factor 2 and nuclear factor-kappaB in rats. J Pineal Res 2010; 48: 239-250.
    • (2010) J Pineal Res , vol.48 , pp. 239-250
    • Jung, K.H.1    Hong, S.W.2    Zheng, H.M.3
  • 52
    • 84872685423 scopus 로고    scopus 로고
    • A review of the molecular aspects of melatonin anti-inflammatory actions: Recent insights and new perspectives
    • Mauriz JL, Collado PS, Veneroso C, Reiter RJ, Gonzalez- Gallego J. A review of the molecular aspects of melatonin anti-inflammatory actions: recent insights and new perspectives. J Pineal Res 2013; 54: 1-14.
    • (2013) J Pineal Res , vol.54 , pp. 1-14
    • Mauriz, J.L.1    Collado, P.S.2    Veneroso, C.3    Reiter, R.J.4    Gonzalez-Gallego, J.5
  • 53
    • 84922815620 scopus 로고    scopus 로고
    • Melatonin decreases muscular oxidative stress and inflammation induced by strenuous exercise and stimulates growth factor synthesis
    • Borges LDA S, Dermargos A, DA Silva Junior EP, et al. Melatonin decreases muscular oxidative stress and inflammation induced by strenuous exercise and stimulates growth factor synthesis. J Pineal Res 2015; 58: 166-172.
    • (2015) J Pineal Res , vol.58 , pp. 166-172
    • Borges, L.1    Dermargos, A.2    Da Silva Junior, E.P.3
  • 54
    • 67349156656 scopus 로고    scopus 로고
    • Effects of Baicalin and Octreotide on the serum TNF-alpha level and apoptosis in multiple organs of rats with severe acute pancreatitis
    • Tian H, Zhang X, Wu C, et al. Effects of Baicalin and Octreotide on the serum TNF-alpha level and apoptosis in multiple organs of rats with severe acute pancreatitis. Inflammation 2009; 32: 191-201.
    • (2009) Inflammation , vol.32 , pp. 191-201
    • Tian, H.1    Zhang, X.2    Wu, C.3
  • 55
    • 22144498398 scopus 로고    scopus 로고
    • Antiinflammatory action of melatonin and its metabolites N1-acetyl-N1-formyl-5-methoxykynuramine (AFMK), and N1-acetyl-5-methoxykynuramine (AMK) in macrophages
    • Mayo JC, Sainz RM, Tan DX, et al. Antiinflammatory action of melatonin and its metabolites N1-acetyl-N1-formyl-5-methoxykynuramine (AFMK), and N1-acetyl-5-methoxykynuramine (AMK) in macrophages. J Neuroimmunol 2005; 165: 139-149.
    • (2005) J Neuroimmunol , vol.165 , pp. 139-149
    • Mayo, J.C.1    Sainz, R.M.2    Tan, D.X.3
  • 56
    • 84947426115 scopus 로고    scopus 로고
    • Kynuramines induce overexpression of heat shock proteins and M1/M2 receptors
    • Leja-Szpak A, Pierzchalski P, Goralska M, et al. Kynuramines induce overexpression of heat shock proteins and M1/M2 receptors J Physiol Pharmacol 2015; 66: 711-718.
    • (2015) J Physiol Pharmacol , vol.66 , pp. 711-718
    • Leja-Szpak, A.1    Pierzchalski, P.2    Goralska, M.3
  • 57
    • 0037966074 scopus 로고    scopus 로고
    • Radioimmunoassay of N1-acetyl-5-methoxykynuramine (AMK); a melatonin oxidative metabolite
    • Harthe C, Claudy D, Dechaud H, Vivien-Roels B, Pevet P, Claustrat B. Radioimmunoassay of N1-acetyl-5-methoxykynuramine (AMK); a melatonin oxidative metabolite. Life Sci 2003; 73: 1587-1597.
    • (2003) Life Sci , vol.73 , pp. 1587-1597
    • Harthe, C.1    Claudy, D.2    Dechaud, H.3    Vivien-Roels, B.4    Pevet, P.5    Claustrat, B.6
  • 58
    • 25144445731 scopus 로고    scopus 로고
    • High concentration of melatonin metabolite N1-acetyl-N1-formyl-5-methoxykynuramine, in cerebrospinal fluid of patients with meningitis: A possible immunomodulatory mechanism
    • Silva SO, Ximenes VF, Livramento JA, Catalani LH, Campa A. High concentration of melatonin metabolite N1-acetyl-N1-formyl-5-methoxykynuramine, in cerebrospinal fluid of patients with meningitis: a possible immunomodulatory mechanism. J Pineal Res 2005; 39: 302-306.
    • (2005) J Pineal Res , vol.39 , pp. 302-306
    • Silva, S.O.1    Ximenes, V.F.2    Livramento, J.A.3    Catalani, L.H.4    Campa, A.5


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