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Volumn 52, Issue 3, 2017, Pages 373-388

Vitamin D Deficiency and Rheumatoid Arthritis

Author keywords

Experimental arthritis; Immunomodulation; Proteoglycan; Rheumatoid arthritis; Tolerance; Vitamin D

Indexed keywords

CALCITRIOL; PROTEOGLYCAN; VITAMIN D; ANTIINFLAMMATORY AGENT;

EID: 84982840471     PISSN: 10800549     EISSN: 15590267     Source Type: Journal    
DOI: 10.1007/s12016-016-8577-0     Document Type: Review
Times cited : (48)

References (129)
  • 1
    • 33744828321 scopus 로고    scopus 로고
    • Vitamin D in foods and as supplements
    • COI: 1:CAS:528:DC%2BD28XlsFKrsbw%3D, PID: 16618499
    • Lamberg-Allardt C (2006) Vitamin D in foods and as supplements. Prog Biophys Mol Biol 92:33–38. doi:10.1016/j.pbiomolbio.2006.02.017
    • (2006) Prog Biophys Mol Biol , vol.92 , pp. 33-38
    • Lamberg-Allardt, C.1
  • 2
    • 84856469462 scopus 로고    scopus 로고
    • Vitamin D and the immune system
    • COI: 1:CAS:528:DC%2BC3MXhtFCqtrzK, PID: 21527855
    • Aranow C (2011) Vitamin D and the immune system. J Investig Med 59:881–886. doi:10.231/JIM.0b013e31821b8755
    • (2011) J Investig Med , vol.59 , pp. 881-886
    • Aranow, C.1
  • 3
    • 0037302906 scopus 로고    scopus 로고
    • Vitamin D: a millennium perspective
    • COI: 1:CAS:528:DC%2BD3sXntlyksQ%3D%3D, PID: 12520530
    • Holick MF (2003) Vitamin D: a millennium perspective. J Cell Biochem 88:296–307. doi:10.1002/jcb.10338
    • (2003) J Cell Biochem , vol.88 , pp. 296-307
    • Holick, M.F.1
  • 5
    • 77951937330 scopus 로고    scopus 로고
    • Identification of two distinct cell binding sequences in the vitamin D binding protein
    • COI: 1:CAS:528:DC%2BC3cXkvFeltLo%3D, PID: 20211661
    • Zhang J, Habiel DM, Ramadass M, Kew RR (2010) Identification of two distinct cell binding sequences in the vitamin D binding protein. Biochim Biophys Acta 1803:623–639. doi:10.1016/j.bbamcr.2010.02.010
    • (2010) Biochim Biophys Acta , vol.1803 , pp. 623-639
    • Zhang, J.1    Habiel, D.M.2    Ramadass, M.3    Kew, R.R.4
  • 6
    • 43549124563 scopus 로고    scopus 로고
    • 2+ absorption in health and disease
    • COI: 1:CAS:528:DC%2BD1cXkt1eqtrg%3D, PID: 17850211
    • 2+ absorption in health and disease. Annu Rev Physiol 70:257–271. doi:10.1146/annurev.physiol.69.031905.161003
    • (2008) Annu Rev Physiol , vol.70 , pp. 257-271
    • Suzuki, Y.1    Landowski, C.P.2    Hediger, M.A.3
  • 7
    • 79251639628 scopus 로고    scopus 로고
    • Vitamin D deficiency in 2010: health benefits of vitamin D and sunlight: a D-bate
    • COI: 1:CAS:528:DC%2BC3MXhtVemt7g%3D, PID: 21263437
    • Holick MF (2011) Vitamin D deficiency in 2010: health benefits of vitamin D and sunlight: a D-bate. Nat Rev Endocrinol 7:73–75. doi:10.1038/nrendo.2010.234
    • (2011) Nat Rev Endocrinol , vol.7 , pp. 73-75
    • Holick, M.F.1
  • 8
    • 79960104336 scopus 로고    scopus 로고
    • Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline
    • COI: 1:CAS:528:DC%2BC3MXptlSku7o%3D, PID: 21646368
    • Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, Murad MH, Weaver CM, Endocrine Society (2011) Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 96:1911–1930. doi:10.1210/jc.2011-0385
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 1911-1930
    • Holick, M.F.1    Binkley, N.C.2    Bischoff-Ferrari, H.A.3    Gordon, C.M.4    Hanley, D.A.5    Heaney, R.P.6    Murad, M.H.7    Weaver, C.M.8
  • 9
    • 65049086842 scopus 로고    scopus 로고
    • Dendritic cell tolerogenicity: a key mechanism in immunomodulation by vitamin D receptor agonists
    • COI: 1:CAS:528:DC%2BD1MXltVCrtLs%3D, PID: 19405173
    • Adorini L, Penna G (2009) Dendritic cell tolerogenicity: a key mechanism in immunomodulation by vitamin D receptor agonists. Hum Immunol 70:345–352. doi:10.1016/j.humimm.2009.01.016
    • (2009) Hum Immunol , vol.70 , pp. 345-352
    • Adorini, L.1    Penna, G.2
  • 10
    • 0037195527 scopus 로고    scopus 로고
    • Update on biological actions of 1alpha,25(OH)2-vitamin D3 (rapid effects) and 24R,25(OH)2-vitamin D3
    • COI: 1:CAS:528:DC%2BD38XosFCmsrg%3D, PID: 12431790
    • Norman AW, Okamura WH, Bishop JE, Henry HL (2002) Update on biological actions of 1alpha,25(OH)2-vitamin D3 (rapid effects) and 24R,25(OH)2-vitamin D3. Mol Cell Endocrinol 197:1–13. doi:10.1016/S0303-7207(02)00273-3
    • (2002) Mol Cell Endocrinol , vol.197 , pp. 1-13
    • Norman, A.W.1    Okamura, W.H.2    Bishop, J.E.3    Henry, H.L.4
  • 11
    • 84883776612 scopus 로고    scopus 로고
    • The vitamin D receptor and T cell function
    • COI: 1:CAS:528:DC%2BC3sXhtlGju7nO, PID: 23785369
    • Kongsbak M, Levring TB, Geisler C, von Essen MR (2013) The vitamin D receptor and T cell function. Front Immunol 4:148. doi:10.3389/fimmu.2013.0014
    • (2013) Front Immunol , vol.4 , pp. 148
    • Kongsbak, M.1    Levring, T.B.2    Geisler, C.3    von Essen, M.R.4
  • 12
    • 0032471589 scopus 로고    scopus 로고
    • Gene regulation by vitamin D3
    • COI: 1:CAS:528:DyaK1cXltVSgtr4%3D, PID: 9673449
    • Carlberg C, Polly P (1998) Gene regulation by vitamin D3. Crit Rev Eukaryot Gene Expr 8:19–42. doi:10.1615/CritRevEukarGeneExpr.v8.i1.20
    • (1998) Crit Rev Eukaryot Gene Expr , vol.8 , pp. 19-42
    • Carlberg, C.1    Polly, P.2
  • 13
    • 34447514029 scopus 로고    scopus 로고
    • Vitamin D deficiency
    • COI: 1:CAS:528:DC%2BD2sXotVejsbc%3D, PID: 17634462
    • Holick MF (2007) Vitamin D deficiency. N Engl J Med 357:266–281. doi:10.1056/NEJMra070553
    • (2007) N Engl J Med , vol.357 , pp. 266-281
    • Holick, M.F.1
  • 15
    • 84930959378 scopus 로고    scopus 로고
    • Vitamin D every day to keep the infection away?
    • PID: 26035244
    • Kroner Jde C, Sommer A, Fabri M (2015) Vitamin D every day to keep the infection away? Nutrients 7:4170–4188. doi:10.3390/nu7064170
    • (2015) Nutrients , vol.7 , pp. 4170-4188
    • Kroner Jde, C.1    Sommer, A.2    Fabri, M.3
  • 16
    • 84949492425 scopus 로고    scopus 로고
    • Vitamin D3 enhances bactericidal activity of macrophage against Pseudomonas aeruginosa
    • COI: 1:CAS:528:DC%2BC2MXhvFKisLnO, PID: 26655879
    • Nouari W, Ysmail-Dahlouk L, Aribi M (2016) Vitamin D3 enhances bactericidal activity of macrophage against Pseudomonas aeruginosa. Int Immunopharmacol 30:94–101. doi:10.1016/j.intimp.2015.11.033
    • (2016) Int Immunopharmacol , vol.30 , pp. 94-101
    • Nouari, W.1    Ysmail-Dahlouk, L.2    Aribi, M.3
  • 17
  • 18
    • 84929377526 scopus 로고    scopus 로고
    • Vitamin D and 1,25(OH)2D regulation of T cells
    • COI: 1:CAS:528:DC%2BC2MXpvFKmtb0%3D, PID: 25912039
    • Cantorna MT, Snyder L, Lin YD, Yang L (2015) Vitamin D and 1,25(OH)2D regulation of T cells. Nutrients 7:3011–3021. doi:10.3390/nu7043011
    • (2015) Nutrients , vol.7 , pp. 3011-3021
    • Cantorna, M.T.1    Snyder, L.2    Lin, Y.D.3    Yang, L.4
  • 19
    • 0029018309 scopus 로고
    • Immunosuppressive actions of 1,25-dihydroxyvitamin D3: preferential inhibition of Th1 functions
    • COI: 1:CAS:528:DyaK2MXmt1ahs7w%3D, PID: 7782931
    • Lemire JM, Archer DC, Beck L, Spiegelberg HL (1995) Immunosuppressive actions of 1,25-dihydroxyvitamin D3: preferential inhibition of Th1 functions. J Nutr 125:1704S–1708S
    • (1995) J Nutr , vol.125 , pp. 1704S-1708S
    • Lemire, J.M.1    Archer, D.C.2    Beck, L.3    Spiegelberg, H.L.4
  • 20
    • 0035497752 scopus 로고    scopus 로고
    • 1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells
    • COI: 1:CAS:528:DC%2BD3MXotVSqu7k%3D, PID: 11673504
    • Boonstra A, Barrat FJ, Crain C, Heath VL, Savelkoul HF, O’Garra A (2001) 1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells. J Immunol 167:4974–4980. doi:10.4049/jimmunol.167.9.4974
    • (2001) J Immunol , vol.167 , pp. 4974-4980
    • Boonstra, A.1    Barrat, F.J.2    Crain, C.3    Heath, V.L.4    Savelkoul, H.F.5    O’Garra, A.6
  • 21
    • 0036467344 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D3 inhibits IFN-gamma and IL-4 levels during in vitro polarization of primary murine CD4+ T cells
    • COI: 1:CAS:528:DC%2BD38XpsFemsA%3D%3D, PID: 11801653
    • Staeva-Vieira TP, Freedman LP (2002) 1,25-dihydroxyvitamin D3 inhibits IFN-gamma and IL-4 levels during in vitro polarization of primary murine CD4+ T cells. J Immunol 168:1181–1189. doi:10.4049/jimmunol.168.3.1181
    • (2002) J Immunol , vol.168 , pp. 1181-1189
    • Staeva-Vieira, T.P.1    Freedman, L.P.2
  • 23
    • 84962633638 scopus 로고    scopus 로고
    • Comparative effect of 25(OH)D3 and 1,25(OH)2D3 on Th17 cell differentiation
    • PID: 27041081
    • Fawaz L, Mrad MF, Kazan JM, Sayegh S, Akika R, Khoury SJ (2016) Comparative effect of 25(OH)D3 and 1,25(OH)2D3 on Th17 cell differentiation. Clin Immunol 166–167:59–71. doi:10.1016/j.clim.2016.02.011
    • (2016) Clin Immunol , vol.166-167 , pp. 59-71
    • Fawaz, L.1    Mrad, M.F.2    Kazan, J.M.3    Sayegh, S.4    Akika, R.5    Khoury, S.J.6
  • 24
    • 65249120937 scopus 로고    scopus 로고
    • Calcitriol suppresses antiretinal autoimmunity through inhibitory effects on the Th17 effector response
    • COI: 1:CAS:528:DC%2BD1MXjvFOjtLw%3D, PID: 19342637
    • Tang J, Zhou R, Luger D, Zhu W, Silver PB, Grajewski RS, Su SB, Chan CC, Adorini L, Caspi RR (2009) Calcitriol suppresses antiretinal autoimmunity through inhibitory effects on the Th17 effector response. J Immunol 182:4624–4632. doi:10.4049/jimmunol.0801543
    • (2009) J Immunol , vol.182 , pp. 4624-4632
    • Tang, J.1    Zhou, R.2    Luger, D.3    Zhu, W.4    Silver, P.B.5    Grajewski, R.S.6    Su, S.B.7    Chan, C.C.8    Adorini, L.9    Caspi, R.R.10
  • 25
    • 77958605267 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 inhibits the differentiation and migration of T(H)17 cells to protect against experimental autoimmune encephalomyelitis
    • PID: 20886077
    • Chang JH, Cha HR, Lee DS, Seo KY, Kweon MN (2010) 1,25-Dihydroxyvitamin D3 inhibits the differentiation and migration of T(H)17 cells to protect against experimental autoimmune encephalomyelitis. PLoS One 5:e12925. doi:10.1371/journal.pone.0012925
    • (2010) PLoS One , vol.5
    • Chang, J.H.1    Cha, H.R.2    Lee, D.S.3    Seo, K.Y.4    Kweon, M.N.5
  • 26
    • 0343238444 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D(3) inhibits dendritic cell differentiation and maturation in vitro
    • COI: 1:CAS:528:DC%2BD3cXktVOlsbw%3D, PID: 10812248
    • Berer A, Stöckl J, Majdic O, Wagner T, Kollars M, Lechner K, Geissler K, Oehler L (2000) 1,25-Dihydroxyvitamin D(3) inhibits dendritic cell differentiation and maturation in vitro. Exp Hematol 28:575–583. doi:10.1016/S0301-472X(00)00143-0
    • (2000) Exp Hematol , vol.28 , pp. 575-583
    • Berer, A.1    Stöckl, J.2    Majdic, O.3    Wagner, T.4    Kollars, M.5    Lechner, K.6    Geissler, K.7    Oehler, L.8
  • 27
    • 36749003219 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells in health and disease: friend and foe!
    • COI: 1:CAS:528:DC%2BD1cXht12mtbg%3D, PID: 17951127
    • Adler HS, Steinbrink K (2007) Tolerogenic dendritic cells in health and disease: friend and foe! Eur J Dermatol 17:476–491. doi:10.1684/ejd.2007.0262
    • (2007) Eur J Dermatol , vol.17 , pp. 476-491
    • Adler, H.S.1    Steinbrink, K.2
  • 28
    • 77954141914 scopus 로고    scopus 로고
    • FOXP3+ regulatory T cells in the human immune system
    • COI: 1:CAS:528:DC%2BC3cXnsFKitLY%3D, PID: 20559327
    • Sakaguchi S, Miyara M, Costantino CM, Hafler DA (2010) FOXP3+ regulatory T cells in the human immune system. Nat Rev Immunol 10:490–500. doi:10.1038/nri2785
    • (2010) Nat Rev Immunol , vol.10 , pp. 490-500
    • Sakaguchi, S.1    Miyara, M.2    Costantino, C.M.3    Hafler, D.A.4
  • 29
    • 27744595600 scopus 로고    scopus 로고
    • Expression of the inhibitory receptor ILT3 on dendritic cells is dispensable for induction of CD4+Foxp3+ regulatory T cells by 1,25-dihydroxyvitamin D3
    • COI: 1:CAS:528:DC%2BD2MXht1ehsbzJ, PID: 16030186
    • Penna G, Roncari A, Amuchastegui S, Daniel KC, Berti E, Colonna M, Adorini L (2005) Expression of the inhibitory receptor ILT3 on dendritic cells is dispensable for induction of CD4+Foxp3+ regulatory T cells by 1,25-dihydroxyvitamin D3. Blood 106:3490–3497. doi:10.1182/blood-2005-05-2044
    • (2005) Blood , vol.106 , pp. 3490-3497
    • Penna, G.1    Roncari, A.2    Amuchastegui, S.3    Daniel, K.C.4    Berti, E.5    Colonna, M.6    Adorini, L.7
  • 30
    • 0036020679 scopus 로고    scopus 로고
    • A 1alpha,25-dihydroxyvitamin D(3) analog enhances regulatory T-cells and arrests autoimmune diabetes in NOD mice
    • COI: 1:CAS:528:DC%2BD38XjtlGmt7w%3D, PID: 11978632
    • Gregori S, Giarratana N, Smiroldo S, Uskokovic M, Adorini L (2002) A 1alpha,25-dihydroxyvitamin D(3) analog enhances regulatory T-cells and arrests autoimmune diabetes in NOD mice. Diabetes 51:1367–1374. doi:10.2337/diabetes.51.5.1367
    • (2002) Diabetes , vol.51 , pp. 1367-1374
    • Gregori, S.1    Giarratana, N.2    Smiroldo, S.3    Uskokovic, M.4    Adorini, L.5
  • 31
    • 68949140898 scopus 로고    scopus 로고
    • Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis
    • PID: 19675671
    • Smolders J, Thewissen M, Peelen E, Menheere P, Tervaert JW, Damoiseaux J, Hupperts R (2009) Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis. PLoS One 4:e6635. doi:10.1371/journal.pone.0006635
    • (2009) PLoS One , vol.4
    • Smolders, J.1    Thewissen, M.2    Peelen, E.3    Menheere, P.4    Tervaert, J.W.5    Damoiseaux, J.6    Hupperts, R.7
  • 32
    • 33750314525 scopus 로고    scopus 로고
    • IL-10 signaling is essential for 1,25-dihydroxyvitamin D3-mediated inhibition of experimental autoimmune encephalomyelitis
    • COI: 1:CAS:528:DC%2BD28XhtFSns7zL, PID: 17056528
    • Spach KM, Nashold FE, Dittel BN, Hayes CE (2006) IL-10 signaling is essential for 1,25-dihydroxyvitamin D3-mediated inhibition of experimental autoimmune encephalomyelitis. J Immunol 177:6030–6037. doi:10.4049/jimmunol.177.9.6030
    • (2006) J Immunol , vol.177 , pp. 6030-6037
    • Spach, K.M.1    Nashold, F.E.2    Dittel, B.N.3    Hayes, C.E.4
  • 33
    • 77951880110 scopus 로고    scopus 로고
    • Vitamin D and autoimmune rheumatologic disorders
    • COI: 1:CAS:528:DC%2BC3cXht1egsLfM, PID: 20146942
    • Pelajo CF, Lopez-Benitez JM, Miller LC (2010) Vitamin D and autoimmune rheumatologic disorders. Autoimmun Rev 9:507–510. doi:10.1016/j.autrev.2010.02.011
    • (2010) Autoimmun Rev , vol.9 , pp. 507-510
    • Pelajo, C.F.1    Lopez-Benitez, J.M.2    Miller, L.C.3
  • 34
    • 29844438189 scopus 로고    scopus 로고
    • UVR, vitamin D and three autoimmune diseases—multiple sclerosis, type 1 diabetes, rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BD2MXhtlektrbJ, PID: 15971932
    • Ponsonby AL, Lucas RM, van der Mei IA (2005) UVR, vitamin D and three autoimmune diseases—multiple sclerosis, type 1 diabetes, rheumatoid arthritis. Photochem Photobiol 81:1267–1275. doi:10.1562/2005-02-15-IR-441
    • (2005) Photochem Photobiol , vol.81 , pp. 1267-1275
    • Ponsonby, A.L.1    Lucas, R.M.2    van der Mei, I.A.3
  • 36
    • 84864234218 scopus 로고    scopus 로고
    • Does vitamin D affect disease severity in patients with ankylosing spondylitis?
    • COI: 1:CAS:528:DC%2BC38XhtlymtLrL
    • Durmus B, Altay Z, Baysal O, Ersoy Y (2012) Does vitamin D affect disease severity in patients with ankylosing spondylitis? Chin Med J (Engl) 125:2511–2515. doi:10.3760/cma.j.issn.0366-6999.2012.14.021
    • (2012) Chin Med J (Engl) , vol.125 , pp. 2511-2515
    • Durmus, B.1    Altay, Z.2    Baysal, O.3    Ersoy, Y.4
  • 38
    • 81255209570 scopus 로고    scopus 로고
    • Seasonal variation in vitamin D levels in psoriatic arthritis patients from different latitudes and its association with clinical outcomes
    • COI: 1:CAS:528:DC%2BC3MXhsV2it7zP
    • Touma Z, Eder L, Zisman D, Feld J, Chandran V, Rosen CF, Shen H, Cook RJ, Gladman DD (2011) Seasonal variation in vitamin D levels in psoriatic arthritis patients from different latitudes and its association with clinical outcomes. Arthritis Care Res (Hoboken) 63:1440–1447. doi:10.1002/acr.20530
    • (2011) Arthritis Care Res (Hoboken) , vol.63 , pp. 1440-1447
    • Touma, Z.1    Eder, L.2    Zisman, D.3    Feld, J.4    Chandran, V.5    Rosen, C.F.6    Shen, H.7    Cook, R.J.8    Gladman, D.D.9
  • 39
    • 84873334895 scopus 로고    scopus 로고
    • Vitamin D deficiency and risk for rheumatic diseases: an update
    • COI: 1:CAS:528:DC%2BC3sXitVCgtro%3D, PID: 23370372
    • Gatenby P, Lucas R, Swaminathan A (2013) Vitamin D deficiency and risk for rheumatic diseases: an update. Curr Opin Rheumatol 25:184–191. doi:10.1097/BOR.0b013e32835cfc16
    • (2013) Curr Opin Rheumatol , vol.25 , pp. 184-191
    • Gatenby, P.1    Lucas, R.2    Swaminathan, A.3
  • 41
    • 79957645587 scopus 로고    scopus 로고
    • Serum 25-OH vitamin D concentrations are linked with various clinical aspects in patients with systemic sclerosis: a retrospective cohort study and review of the literature
    • COI: 1:CAS:528:DC%2BC3MXntFGntbo%3D, PID: 21320645
    • Arnson Y, Amital H, Agmon-Levin N, Alon D, Sánchez-Castañón M, López-Hoyos M, Matucci-Cerinic M, Szücs G, Shapira Y, Szekanecz Z, Shoenfeld Y (2011) Serum 25-OH vitamin D concentrations are linked with various clinical aspects in patients with systemic sclerosis: a retrospective cohort study and review of the literature. Autoimmun Rev 10:490–494. doi:10.1016/j.autrev.2011.02.002
    • (2011) Autoimmun Rev , vol.10 , pp. 490-494
    • Arnson, Y.1    Amital, H.2    Agmon-Levin, N.3    Alon, D.4    Sánchez-Castañón, M.5    López-Hoyos, M.6    Matucci-Cerinic, M.7    Szücs, G.8    Shapira, Y.9    Szekanecz, Z.10    Shoenfeld, Y.11
  • 42
    • 84969498445 scopus 로고    scopus 로고
    • Association between hypovitaminosis D and systemic sclerosis: true or fake?
    • COI: 1:CAS:528:DC%2BC28XptVCltb0%3D, PID: 27154801
    • Bivona G, Agnello L, Pivetti A, Milano S, Scazzone C, Sasso BL, Ciaccio M (2016) Association between hypovitaminosis D and systemic sclerosis: true or fake? Clin Chim Acta 458:115–119. doi:10.1016/j.cca.2016.04.026
    • (2016) Clin Chim Acta , vol.458 , pp. 115-119
    • Bivona, G.1    Agnello, L.2    Pivetti, A.3    Milano, S.4    Scazzone, C.5    Sasso, B.L.6    Ciaccio, M.7
  • 43
    • 61449256513 scopus 로고    scopus 로고
    • Vitamin D involvement in rheumatoid arthritis and systemic lupus erythematosus
    • COI: 1:STN:280:DC%2BD1M7jvVKksQ%3D%3D, PID: 19213751
    • Cutolo M, Otsa K, Paolino S, Yprus M, Veldi T, Seriolo B (2009) Vitamin D involvement in rheumatoid arthritis and systemic lupus erythematosus. Ann Rheum Dis 68:446–447. doi:10.1136/ard.2008.093476
    • (2009) Ann Rheum Dis , vol.68 , pp. 446-447
    • Cutolo, M.1    Otsa, K.2    Paolino, S.3    Yprus, M.4    Veldi, T.5    Seriolo, B.6
  • 44
    • 84858648308 scopus 로고    scopus 로고
    • Vitamin D levels in Chinese patients with systemic lupus erythematosus: relationship with disease activity, vascular risk factors and atherosclerosis
    • COI: 1:CAS:528:DC%2BC38XksVajtbo%3D
    • Mok CC, Birmingham DJ, Leung HW, Hebert LA, Song H, Rovin BH (2012) Vitamin D levels in Chinese patients with systemic lupus erythematosus: relationship with disease activity, vascular risk factors and atherosclerosis. Rheumatology (Oxford) 51:644–52. doi:10.1093/rheumatology/ker212
    • (2012) Rheumatology (Oxford) , vol.51 , pp. 644-652
    • Mok, C.C.1    Birmingham, D.J.2    Leung, H.W.3    Hebert, L.A.4    Song, H.5    Rovin, B.H.6
  • 45
    • 84963579114 scopus 로고    scopus 로고
    • Eppur Si Muove: vitamin D is essential in preventing and modulating SLE
    • COI: 1:CAS:528:DC%2BC28Xht1ens73K, PID: 26811372
    • Azrielant S, Shoenfeld Y (2016) Eppur Si Muove: vitamin D is essential in preventing and modulating SLE. Lupus 25:563–572. doi:10.1177/0961203316629001
    • (2016) Lupus , vol.25 , pp. 563-572
    • Azrielant, S.1    Shoenfeld, Y.2
  • 46
    • 84987657580 scopus 로고    scopus 로고
    • Severe vitamin D deficiency increases the risk for moderate to severe disease activity in Chinese patients with SLE, Lupus
    • Gao CC, Liu SY, Wu ZZ, Li TF, Gao GM, Liu ZS, Zheng ZH (2016) Severe vitamin D deficiency increases the risk for moderate to severe disease activity in Chinese patients with SLE. Lupus. doi: 10.1177/0961203316635289
    • (2016) Zheng ZH
    • Gao, C.C.1    Liu, S.Y.2    Wu, Z.Z.3    Li, T.F.4    Gao, G.M.5    Liu, Z.S.6
  • 48
    • 84930194157 scopus 로고    scopus 로고
    • Vitamin D status is a determinant of atorvastatin effect on carotid intima medial thickening progression rate in children with lupus: an Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE) sub-study
    • Robinson A, Tangpricha V, Yow E, Gurion R, Schanberg LE, McComsey GA (2014) Vitamin D status is a determinant of atorvastatin effect on carotid intima medial thickening progression rate in children with lupus: an Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE) sub-study. Lupus Sci Med 10:e000037. doi:10.1136/lupus-2014-000037
    • (2014) Lupus Sci Med , vol.10
    • Robinson, A.1    Tangpricha, V.2    Yow, E.3    Gurion, R.4    Schanberg, L.E.5    McComsey, G.A.6
  • 50
    • 84879867151 scopus 로고    scopus 로고
    • Vitamin D in systemic lupus erythematosus: modest association with disease activity and the urine protein-to-creatinine ratio
    • COI: 1:CAS:528:DC%2BC3sXhtVKhtrbF, PID: 23553077
    • Petri M, Bello KJ, Fang H, Magder LS (2013) Vitamin D in systemic lupus erythematosus: modest association with disease activity and the urine protein-to-creatinine ratio. Arthritis Rheum 65:1865–71. doi:10.1002/art.37953
    • (2013) Arthritis Rheum , vol.65 , pp. 1865-1871
    • Petri, M.1    Bello, K.J.2    Fang, H.3    Magder, L.S.4
  • 51
    • 84896740512 scopus 로고    scopus 로고
    • Association between vitamin D receptor gene BsmI, FokI, ApaI and TaqI polymorphisms and the risk of systemic lupus erythematosus: a meta-analysis
    • COI: 1:CAS:528:DC%2BC3sXhslClsbzM, PID: 24212677
    • Mao S, Huang S (2014) Association between vitamin D receptor gene BsmI, FokI, ApaI and TaqI polymorphisms and the risk of systemic lupus erythematosus: a meta-analysis. Rheumatol Int 34:381–388. doi:10.1007/s00296-013-2898-6
    • (2014) Rheumatol Int , vol.34 , pp. 381-388
    • Mao, S.1    Huang, S.2
  • 52
    • 84953637386 scopus 로고    scopus 로고
    • Lupus erythematosus revisited
    • COI: 1:CAS:528:DC%2BC2MXitVShur7F, PID: 26637330
    • Kuhn A, Wenzel J, Bijl M (2016) Lupus erythematosus revisited. Semin Immunopathol 38:97–112. doi:10.1007/s00281-015-0550-0
    • (2016) Semin Immunopathol. , vol.38 , pp. 97-112
    • Kuhn, A.1    Wenzel, J.2    Bijl, M.3
  • 53
    • 84949186147 scopus 로고    scopus 로고
    • Influence of vitamin D on cell cycle, apoptosis, and some apoptosis-related molecules in systemic lupus erythematosus
    • PID: 26949498
    • Tabasi N, Rastin M, Mahmoudi M, Ghoryani M, Mirfeizi Z, Rabe SZ, Reihani H (2015) Influence of vitamin D on cell cycle, apoptosis, and some apoptosis-related molecules in systemic lupus erythematosus. Iran J Basic Med Sci 18:1107–1111
    • (2015) Iran J Basic Med Sci , vol.18 , pp. 1107-1111
    • Tabasi, N.1    Rastin, M.2    Mahmoudi, M.3    Ghoryani, M.4    Mirfeizi, Z.5    Rabe, S.Z.6    Reihani, H.7
  • 55
    • 84858752604 scopus 로고    scopus 로고
    • Autoimmune disease and gender: plausible mechanisms for the female predominance of autoimmunity
    • COI: 1:CAS:528:DC%2BC38XktlGmtrg%3D, PID: 22079680
    • Quintero OL, Amador-Patarroyo MJ, Montoya-Ortiz G, Rojas-Villarraga A, Anaya JM (2012) Autoimmune disease and gender: plausible mechanisms for the female predominance of autoimmunity. J Autoimmun 38:J109–119. doi:10.1016/j.jaut.2011.10.003
    • (2012) J Autoimmun , vol.38 , pp. J109-J119
    • Quintero, O.L.1    Amador-Patarroyo, M.J.2    Montoya-Ortiz, G.3    Rojas-Villarraga, A.4    Anaya, J.M.5
  • 56
    • 84865375172 scopus 로고    scopus 로고
    • Rheumatoid arthritis: from autoimmunity to synovitis and joint destruction
    • COI: 1:CAS:528:DC%2BC38XovVajurg%3D, PID: 22704962
    • Boissier MC, Semerano L, Challal S, Saidenberg-Kermanac’h N, Falgarone G (2012) Rheumatoid arthritis: from autoimmunity to synovitis and joint destruction. J Autoimmun 39:222–228. doi:10.1016/j.jaut.2012.05.021
    • (2012) J Autoimmun. , vol.39 , pp. 222-228
    • Boissier, M.C.1    Semerano, L.2    Challal, S.3    Saidenberg-Kermanac’h, N.4    Falgarone, G.5
  • 57
    • 84926646555 scopus 로고    scopus 로고
    • Vitamin D status and its association with quality of life, physical activity, and disease activity in rheumatoid arthritis patients
    • PID: 25807091
    • Raczkiewicz A, Kisiel B, Kulig M, Tłustochowicz W (2015) Vitamin D status and its association with quality of life, physical activity, and disease activity in rheumatoid arthritis patients. J Clin Rheumatol 21:126–30. doi:10.1097/RHU.0000000000000233
    • (2015) J Clin Rheumatol , vol.21 , pp. 126-130
    • Raczkiewicz, A.1    Kisiel, B.2    Kulig, M.3    Tłustochowicz, W.4
  • 58
    • 84954486283 scopus 로고    scopus 로고
    • Serum vitamin D level and rheumatoid arthritis disease activity: review and meta-analysis
    • PID: 26751969
    • Lin J, Liu J, Davies ML, Chen W (2016) Serum vitamin D level and rheumatoid arthritis disease activity: review and meta-analysis. PLoS One 11(1):e0146351. doi:10.1371/journal.pone.0146351
    • (2016) PLoS One , vol.11 , Issue.1
    • Lin, J.1    Liu, J.2    Davies, M.L.3    Chen, W.4
  • 59
    • 80054697845 scopus 로고    scopus 로고
    • Supplementation of 1,25-dihydroxyvitamin D3 in patients with treatment naive early rheumatoid arthritis: a randomized controlled trial
    • PID: 22004229
    • Gopinath K, Danda D (2011) Supplementation of 1,25-dihydroxyvitamin D3 in patients with treatment naive early rheumatoid arthritis: a randomized controlled trial. Int J Rheum Dis 14:332–339. doi:10.1111/j.1756-185X.2011.01684.x
    • (2011) Int J Rheum Dis , vol.14 , pp. 332-339
    • Gopinath, K.1    Danda, D.2
  • 60
    • 84863990315 scopus 로고    scopus 로고
    • Efficacy of vitamin D in patients with active rheumatoid arthritis receiving methotrexate therapy
    • COI: 1:CAS:528:DC%2BC38XpsVKntr8%3D, PID: 21523344
    • Salesi M, Farajzadegan Z (2012) Efficacy of vitamin D in patients with active rheumatoid arthritis receiving methotrexate therapy. Rheumatol Int 32:2129–33. doi:10.1007/s00296-011-1944-5
    • (2012) Rheumatol Int , vol.32 , pp. 2129-2133
    • Salesi, M.1    Farajzadegan, Z.2
  • 61
    • 84879887173 scopus 로고    scopus 로고
    • The role of vitamin D supplementation in patients with rheumatic diseases
    • COI: 1:CAS:528:DC%2BC3sXhtVGksLfJ, PID: 23670134
    • Abrahamsen B, Harvey NC (2013) The role of vitamin D supplementation in patients with rheumatic diseases. Nat Rev Rheumatol 9:411–422. doi:10.1038/nrrheum.2013.71
    • (2013) Nat Rev Rheumatol , vol.9 , pp. 411-422
    • Abrahamsen, B.1    Harvey, N.C.2
  • 62
    • 79957814818 scopus 로고    scopus 로고
    • Relationship of focal erosions, bone mineral density, and parathyroid hormone in rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BC3MXptVOqur8%3D, PID: 21459948
    • Rossini M, Bagnato G, Frediani B, Iagnocco A, LA Montagna G, Minisola G, Caminiti M, Varenna M, Adami S (2011) Relationship of focal erosions, bone mineral density, and parathyroid hormone in rheumatoid arthritis. J Rheumatol 38:997–1002. doi:10.3899/jrheum.100829
    • (2011) J Rheumatol , vol.38 , pp. 997-1002
    • Rossini, M.1    Bagnato, G.2    Frediani, B.3    Iagnocco, A.4    Lamontagna, G.5    Minisola, G.6    Caminiti, M.7    Varenna, M.8    Adami, S.9
  • 63
    • 0038011833 scopus 로고    scopus 로고
    • Evolving concepts of rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BD3sXjs1ynu7c%3D, PID: 12748655
    • Firestein GS (2003) Evolving concepts of rheumatoid arthritis. Nature 423:356–361. doi:10.1038/nature01661
    • (2003) Nature , vol.423 , pp. 356-361
    • Firestein, G.S.1
  • 64
    • 40549108688 scopus 로고    scopus 로고
    • Cells of the synovium in rheumatoid arthritis. Macrophages
    • PID: 18177511
    • Kinne RW, Stuhlmüller B, Burmester GR (2007) Cells of the synovium in rheumatoid arthritis. Macrophages. Arthritis Res Ther 9:224. doi:10.1186/ar2333
    • (2007) Arthritis Res Ther , vol.9 , pp. 224
    • Kinne, R.W.1    Stuhlmüller, B.2    Burmester, G.R.3
  • 65
    • 33646370647 scopus 로고    scopus 로고
    • TNF down-modulates the function of human CD4+CD25hi T-regulatory cells
    • COI: 1:CAS:528:DC%2BD28XmsVOmurk%3D, PID: 16537805
    • Valencia X, Stephens G, Goldbach-Mansky R, Wilson M, Shevach EM, Lipsky PE (2006) TNF down-modulates the function of human CD4+CD25hi T-regulatory cells. Blood 108:253–261. doi:10.1182/blood-2005-11-4567
    • (2006) Blood , vol.108 , pp. 253-261
    • Valencia, X.1    Stephens, G.2    Goldbach-Mansky, R.3    Wilson, M.4    Shevach, E.M.5    Lipsky, P.E.6
  • 66
    • 84943821219 scopus 로고    scopus 로고
    • The role of cytokines in the pathogenesis of rheumatoid arthritis—practical and potential application of cytokines as biomarkers and targets of personalized therapy
    • COI: 1:CAS:528:DC%2BC2MXhsVajs7nF, PID: 26321413
    • Brzustewicz E, Bryl E (2015) The role of cytokines in the pathogenesis of rheumatoid arthritis—practical and potential application of cytokines as biomarkers and targets of personalized therapy. Cytokine 76:527–36. doi:10.1016/j.cyto.2015.08.260
    • (2015) Cytokine , vol.76 , pp. 527-536
    • Brzustewicz, E.1    Bryl, E.2
  • 67
    • 84960934172 scopus 로고    scopus 로고
    • Understanding the role of cytokines in the pathogenesis of rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BC28XivVKlsrs%3D, PID: 26883280
    • Mateen S, Zafar A, Moin S, Khan AQ, Zubair S (2016) Understanding the role of cytokines in the pathogenesis of rheumatoid arthritis. Clin Chim Acta 455:161–171. doi:10.1016/j.cca.2016.02.010
    • (2016) Clin Chim Acta. , vol.455 , pp. 161-171
    • Mateen, S.1    Zafar, A.2    Moin, S.3    Khan, A.Q.4    Zubair, S.5
  • 68
    • 84960093847 scopus 로고    scopus 로고
    • Current concepts in the management of rheumatoid arthritis
    • PID: 26932398
    • Tanaka Y (2016) Current concepts in the management of rheumatoid arthritis. Korean J Intern Med 31:210–218. doi:10.3904/kjim.2015.137
    • (2016) Korean J Intern Med. , vol.31 , pp. 210-218
    • Tanaka, Y.1
  • 69
    • 84895550322 scopus 로고    scopus 로고
    • Self-antigen presentation by dendritic cells in autoimmunity
    • PID: 24592266
    • Hopp AK, Rupp A, Lukacs-Kornek V (2014) Self-antigen presentation by dendritic cells in autoimmunity. Front Immunol 5:55. doi:10.3389/fimmu.2014.00055
    • (2014) Front Immunol. , vol.5 , pp. 55
    • Hopp, A.K.1    Rupp, A.2    Lukacs-Kornek, V.3
  • 70
    • 84950107630 scopus 로고    scopus 로고
    • Mechanisms involved in triggering rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BC2MXitVeqtrzN, PID: 26683152
    • Catrina AI, Joshua V, Klareskog L, Malmström V (2016) Mechanisms involved in triggering rheumatoid arthritis. Immunol Rev 269:162–174. doi:10.1111/imr.12379
    • (2016) Immunol Rev , vol.269 , pp. 162-174
    • Catrina, A.I.1    Joshua, V.2    Klareskog, L.3    Malmström, V.4
  • 72
    • 33747203086 scopus 로고    scopus 로고
    • Immunopathologic role of B lymphocytes in rheumatoid arthritis: rationale of B cell-directed therapy
    • COI: 1:CAS:528:DC%2BD28XhtVyns7nN, PID: 16920569
    • Martinez-Gamboa L, Brezinschek HP, Burmester GR, Dörner T (2006) Immunopathologic role of B lymphocytes in rheumatoid arthritis: rationale of B cell-directed therapy. Autoimmun Rev 5:437–442. doi:10.1016/j.autrev.2006.02.004
    • (2006) Autoimmun Rev , vol.5 , pp. 437-442
    • Martinez-Gamboa, L.1    Brezinschek, H.P.2    Burmester, G.R.3    Dörner, T.4
  • 73
    • 84988429303 scopus 로고    scopus 로고
    • Therapeutic implications of autoantibodies in rheumatoid arthritis
    • PID: 27252890
    • Aletaha D, Blüml S (2016) Therapeutic implications of autoantibodies in rheumatoid arthritis. RMD Open 2:e000009. doi:10.1136/rmdopen-2014-000009
    • (2016) RMD Open , vol.2
    • Aletaha, D.1    Blüml, S.2
  • 74
    • 33646348123 scopus 로고    scopus 로고
    • The HLA-DRB1 shared epitope alleles are primarily a risk factor for anti-cyclic citrullinated peptide antibodies and are not an independent risk factor for the development of rheumatoid arthritis
    • van der Helm-van Mil AH, Verpoort KN, Breedveld FC, Huizinga TW, Toes RE, de Vries RR (2006) The HLA-DRB1 shared epitope alleles are primarily a risk factor for anti-cyclic citrullinated peptide antibodies and are not an independent risk factor for the development of rheumatoid arthritis. Arthritis Rheum 54:1117–1121. doi:10.1002/art.21739
    • (2006) Arthritis Rheum , vol.54 , pp. 1117-1121
    • van der Helm-van Mil, A.H.1    Verpoort, K.N.2    Breedveld, F.C.3    Huizinga, T.W.4    Toes, R.E.5    de Vries, R.R.6
  • 76
    • 84915749878 scopus 로고    scopus 로고
    • Arthritogenic T cells in autoimmune arthritis
    • COI: 1:CAS:528:DC%2BC2cXitVSnsbfI, PID: 25450406
    • Komatsu N, Takayanagi H (2015) Arthritogenic T cells in autoimmune arthritis. Int J Biochem Cell Biol 58:92–96. doi:10.1016/j.biocel.2014.11.008
    • (2015) Int J Biochem Cell Biol , vol.58 , pp. 92-96
    • Komatsu, N.1    Takayanagi, H.2
  • 78
    • 84888871863 scopus 로고    scopus 로고
    • The plasticity of human Treg and Th17 cells and its role in autoimmunity
    • COI: 1:CAS:528:DC%2BC3sXhsleisr3F, PID: 24211039
    • Kleinewietfeld M, Hafler DA (2013) The plasticity of human Treg and Th17 cells and its role in autoimmunity. Semin Immunol 25:305–312. doi:10.1016/j.smim.2013.10.009
    • (2013) Semin Immunol , vol.25 , pp. 305-312
    • Kleinewietfeld, M.1    Hafler, D.A.2
  • 79
    • 0032939156 scopus 로고    scopus 로고
    • Human interleukin-17: a T cell-derived proinflammatory cytokine produced by the rheumatoid synovium
    • COI: 1:CAS:528:DyaK1MXjtlKjurs%3D, PID: 10323452
    • Chabaud M, Durand JM, Buchs N, Fossiez F, Page G, Frappart L, Miossec P (1999) Human interleukin-17: a T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. Arthritis Rheum 42:963–970. doi:10.1002/1529-0131(199905)42:5<963::AID-ANR15>3.0.CO;2-E
    • (1999) Arthritis Rheum , vol.42 , pp. 963-970
    • Chabaud, M.1    Durand, J.M.2    Buchs, N.3    Fossiez, F.4    Page, G.5    Frappart, L.6    Miossec, P.7
  • 80
    • 3543140687 scopus 로고    scopus 로고
    • Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNF-alpha therapy
    • COI: 1:CAS:528:DC%2BD2cXmsVCktbg%3D, PID: 15280421
    • Ehrenstein MR, Evans JG, Singh A, Moore S, Warnes G, Isenberg DA, Mauri C (2004) Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNF-alpha therapy. J Exp Med 200:277–285. doi:10.1084/jem.20040165
    • (2004) J Exp Med , vol.200 , pp. 277-285
    • Ehrenstein, M.R.1    Evans, J.G.2    Singh, A.3    Moore, S.4    Warnes, G.5    Isenberg, D.A.6    Mauri, C.7
  • 81
    • 4444300314 scopus 로고    scopus 로고
    • CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid
    • PID: 15457445
    • van Amelsfort JM, Jacobs KM, Bijlsma JW, Lafeber FP, Taams LS (2004) CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid. Arthritis Rheum 50:2775–2785. doi:10.1002/art.20499
    • (2004) Arthritis Rheum , vol.50 , pp. 2775-2785
    • van Amelsfort, J.M.1    Jacobs, K.M.2    Bijlsma, J.W.3    Lafeber, F.P.4    Taams, L.S.5
  • 82
    • 84922406776 scopus 로고    scopus 로고
    • The role of the synovial fibroblast in rheumatoid arthritis pathogenesis
    • COI: 1:CAS:528:DC%2BC2MXitFCisL4%3D, PID: 25603041
    • Turner JD, Filer A (2015) The role of the synovial fibroblast in rheumatoid arthritis pathogenesis. Curr Opin Rheumatol 27:175–182. doi:10.1097/BOR.0000000000000148
    • (2015) Curr Opin Rheumatol , vol.27 , pp. 175-182
    • Turner, J.D.1    Filer, A.2
  • 83
    • 39549118264 scopus 로고    scopus 로고
    • Cells of the synovium in rheumatoid arthritis
    • PID: 18001488
    • Otero M, Goldring MB (2007) Cells of the synovium in rheumatoid arthritis. Chondrocytes Arthritis Res Ther 9:220. doi:10.1186/ar2292
    • (2007) Chondrocytes. Arthritis Res Ther , vol.9 , pp. 220
    • Otero, M.1    Goldring, M.B.2
  • 84
    • 34247589636 scopus 로고    scopus 로고
    • Cells of the synovium in rheumatoid arthritis. Osteoclasts
    • PID: 17316459
    • Schett G (2007) Cells of the synovium in rheumatoid arthritis. Osteoclasts. Arthritis Res Ther 9:203. doi:10.1186/ar2110
    • (2007) Arthritis Res Ther. , vol.9 , pp. 203
    • Schett, G.1
  • 85
    • 84943616893 scopus 로고    scopus 로고
    • Vitamin D in rheumatoid arthritis—towards clinical application
    • COI: 1:CAS:528:DC%2BC2MXhs1Chu7zN, PID: 26481434
    • Jeffery LE, Raza K, Hewison M (2016) Vitamin D in rheumatoid arthritis—towards clinical application. Nat Rev Rheumatol 12:201–210. doi:10.1038/nrrheum.2015.140
    • (2016) Nat Rev Rheumatol , vol.12 , pp. 201-210
    • Jeffery, L.E.1    Raza, K.2    Hewison, M.3
  • 87
    • 84937861505 scopus 로고    scopus 로고
    • Combination of an antigen-specific therapy and an immunomodulatory treatment to simultaneous block recurrent autoimmunity and alloreactivity in non-obese diabetic mice
    • PID: 26080071
    • Fousteri G, Jofra T, Di Fonte R, Battaglia M (2015) Combination of an antigen-specific therapy and an immunomodulatory treatment to simultaneous block recurrent autoimmunity and alloreactivity in non-obese diabetic mice. PLoS One 10:e0127631. doi:10.1371/journal.pone.0127631
    • (2015) PLoS One , vol.10
    • Fousteri, G.1    Jofra, T.2    Di Fonte, R.3    Battaglia, M.4
  • 88
    • 84964649159 scopus 로고    scopus 로고
    • Autoantigen-specific immunosuppression with tolerogenic peripheral blood cells prevents relapses in a mouse model of relapsing-remitting multiple sclerosis
    • PID: 27131971
    • Kleist C, Mohr E, Gaikwad S, Dittmar L, Kuerten S, Platten M, Mier W, Schmitt M, Opelz G, Terness P (2016) Autoantigen-specific immunosuppression with tolerogenic peripheral blood cells prevents relapses in a mouse model of relapsing-remitting multiple sclerosis. J Transl Med 14:99. doi:10.1186/s12967-016-0860-6
    • (2016) J Transl Med , vol.14 , pp. 99
    • Kleist, C.1    Mohr, E.2    Gaikwad, S.3    Dittmar, L.4    Kuerten, S.5    Platten, M.6    Mier, W.7    Schmitt, M.8    Opelz, G.9    Terness, P.10
  • 89
    • 0033738813 scopus 로고    scopus 로고
    • Antigen-specific therapy for autoimmune disease
    • COI: 1:CAS:528:DC%2BD3cXosVKjsrk%3D, PID: 11102776
    • Harrison LC, Hafler DA (2000) Antigen-specific therapy for autoimmune disease. Curr Opin Immunol 12:704–711. doi:10.1016/S0952-7915(00)00166-7
    • (2000) Curr Opin Immunol , vol.12 , pp. 704-711
    • Harrison, L.C.1    Hafler, D.A.2
  • 90
    • 78149361779 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells in autoimmune diseases: crucial players in induction and prevention of autoimmunity
    • COI: 1:CAS:528:DC%2BC3cXhtl2isLrJ, PID: 20678591
    • Torres-Aguilar H, Blank M, Jara LJ, Shoenfeld Y (2010) Tolerogenic dendritic cells in autoimmune diseases: crucial players in induction and prevention of autoimmunity. Autoimmun Rev 10:8–17. doi:10.1016/j.autrev.2010.07.015
    • (2010) Autoimmun Rev , vol.10 , pp. 8-17
    • Torres-Aguilar, H.1    Blank, M.2    Jara, L.J.3    Shoenfeld, Y.4
  • 91
    • 0345827684 scopus 로고    scopus 로고
    • Dendritic cells: emerging pharmacological targets of immunosuppressive drugs
    • COI: 1:CAS:528:DC%2BD2cXkvVCisg%3D%3D, PID: 14704765
    • Hackstein H, Thomson AW (2004) Dendritic cells: emerging pharmacological targets of immunosuppressive drugs. Nat Rev Immunol 4:24–34. doi:10.1038/nri1256
    • (2004) Nat Rev Immunol , vol.4 , pp. 24-34
    • Hackstein, H.1    Thomson, A.W.2
  • 92
    • 1242295281 scopus 로고    scopus 로고
    • Pharmacological induction of tolerogenic dendritic cells and regulatory T cells
    • COI: 1:CAS:528:DC%2BD2cXht1KhtbY%3D, PID: 15036236
    • Adorini L, Giarratana N, Penna G (2004) Pharmacological induction of tolerogenic dendritic cells and regulatory T cells. Semin Immunol 16:127–134. doi:10.1016/j.smim.2003.12.008
    • (2004) Semin Immunol , vol.16 , pp. 127-134
    • Adorini, L.1    Giarratana, N.2    Penna, G.3
  • 95
    • 84873364466 scopus 로고    scopus 로고
    • Vitamin D in allergic disease: shedding light on a complex problem
    • COI: 1:CAS:528:DC%2BC3sXhvFSktr8%3D, PID: 23374263
    • Muehleisen B, Gallo RL (2013) Vitamin D in allergic disease: shedding light on a complex problem. J Allergy Clin Immunol 131:324–329. doi:10.1016/j.jaci.2012.12.1562
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 324-329
    • Muehleisen, B.1    Gallo, R.L.2
  • 96
    • 0031908097 scopus 로고    scopus 로고
    • 1,25-Dihydroxycholecalciferol inhibits the progression of arthritis in murine models of human arthritis
    • COI: 1:CAS:528:DyaK1cXnt1Gluw%3D%3D, PID: 9430604
    • Cantorna MT, Hayes CE, DeLuca HF (1998) 1,25-Dihydroxycholecalciferol inhibits the progression of arthritis in murine models of human arthritis. J Nutr 128:68–72
    • (1998) J Nutr , vol.128 , pp. 68-72
    • Cantorna, M.T.1    Hayes, C.E.2    DeLuca, H.F.3
  • 97
    • 84883209440 scopus 로고    scopus 로고
    • Vitamin D in rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BC3sXhtFyht77I, PID: 23862559
    • Haga HJ (2013) Vitamin D in rheumatoid arthritis. Expert Rev Clin Immunol 9:591–593. doi:10.1586/1744666X.2013.811177
    • (2013) Expert Rev Clin Immunol , vol.9 , pp. 591-593
    • Haga, H.J.1
  • 98
    • 79952677650 scopus 로고    scopus 로고
    • Dendritic cells modified by vitamin D: future immunotherapy for autoimmune diseases
    • COI: 1:CAS:528:DC%2BC3MXovVChsL0%3D, PID: 21419267
    • Pedersen AW, Claesson MH, Zocca MB (2011) Dendritic cells modified by vitamin D: future immunotherapy for autoimmune diseases. Vitam Horm 86:63–82. doi:10.1016/B978-0-12-386960-9.00003-4
    • (2011) Vitam Horm , vol.86 , pp. 63-82
    • Pedersen, A.W.1    Claesson, M.H.2    Zocca, M.B.3
  • 99
    • 0035170432 scopus 로고    scopus 로고
    • Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells
    • COI: 1:CAS:528:DC%2BD3MXotF2gtr0%3D, PID: 11590405
    • Albert ML, Jegathesan M, Darnell RB (2001) Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells. Nat Immunol 2:1010–1017. doi:10.1038/ni722
    • (2001) Nat Immunol , vol.2 , pp. 1010-1017
    • Albert, M.L.1    Jegathesan, M.2    Darnell, R.B.3
  • 100
    • 0037033427 scopus 로고    scopus 로고
    • Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity
    • COI: 1:CAS:528:DC%2BD38XjslKqtQ%3D%3D, PID: 11781361
    • Menges M, Rössner S, Voigtländer C, Schindler H, Kukutsch NA, Bogdan C, Erb K, Schuler G, Lutz MB (2002) Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity. J Exp Med 195:15–21. doi:10.1084/jem.20011341
    • (2002) J Exp Med , vol.195 , pp. 15-21
    • Menges, M.1    Rössner, S.2    Voigtländer, C.3    Schindler, H.4    Kukutsch, N.A.5    Bogdan, C.6    Erb, K.7    Schuler, G.8    Lutz, M.B.9
  • 102
    • 84869815306 scopus 로고    scopus 로고
    • Availability of 25-hydroxyvitamin D(3) to APCs controls the balance between regulatory and inflammatory T cell responses
    • COI: 1:CAS:528:DC%2BC38Xhs12gt73E, PID: 23087405
    • Jeffery LE, Wood AM, Qureshi OS, Hou TZ, Gardner D, Briggs Z, Kaur S, Raza K, Sansom DM (2012) Availability of 25-hydroxyvitamin D(3) to APCs controls the balance between regulatory and inflammatory T cell responses. J Immunol 189:5155–5164. doi:10.4049/jimmunol.1200786
    • (2012) J Immunol , vol.189 , pp. 5155-5164
    • Jeffery, L.E.1    Wood, A.M.2    Qureshi, O.S.3    Hou, T.Z.4    Gardner, D.5    Briggs, Z.6    Kaur, S.7    Raza, K.8    Sansom, D.M.9
  • 104
    • 51449116424 scopus 로고    scopus 로고
    • CD4+CD25high T cell numbers are enriched in the peripheral blood of patients with rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BD1cXhtFWlsr3M, PID: 18649874
    • Han GM, O'Neil-Andersen NJ, Zurier RB, Lawrence DA (2008) CD4+CD25high T cell numbers are enriched in the peripheral blood of patients with rheumatoid arthritis. Cell Immunol 253:92–101. doi:10.1016/j.cellimm.2008.05.007
    • (2008) Cell Immunol , vol.253 , pp. 92-101
    • Han, G.M.1    O'Neil-Andersen, N.J.2    Zurier, R.B.3    Lawrence, D.A.4
  • 105
    • 84878365850 scopus 로고    scopus 로고
    • Vitamin D supplementation reduces airway hyper-responsiveness and allergic airway inflammation in a murine model
    • COI: 1:CAS:528:DC%2BC3sXosFentLs%3D, PID: 23711130
    • Agrawal T, Gupta GK, Agrawal DK (2013) Vitamin D supplementation reduces airway hyper-responsiveness and allergic airway inflammation in a murine model. Clin Exp Allergy 43:672–683. doi:10.1111/cea.12102
    • (2013) Clin Exp Allergy , vol.43 , pp. 672-683
    • Agrawal, T.1    Gupta, G.K.2    Agrawal, D.K.3
  • 106
    • 84884187623 scopus 로고    scopus 로고
    • Influence of vitamin D status on respiratory infection incidence and immune function during 4 months of winter training in endurance sport athletes
    • PID: 23977722
    • He CS, Handzlik M, Fraser WD, Muhamad A, Preston H, Richardson A, Gleeson M (2013) Influence of vitamin D status on respiratory infection incidence and immune function during 4 months of winter training in endurance sport athletes. Exerc Immunol Rev 19:86–101
    • (2013) Exerc Immunol Rev , vol.19 , pp. 86-101
    • He, C.S.1    Handzlik, M.2    Fraser, W.D.3    Muhamad, A.4    Preston, H.5    Richardson, A.6    Gleeson, M.7
  • 107
    • 84901344676 scopus 로고    scopus 로고
    • The in vitro treatment with vitamin D3 is ineffective on the expression of PKC isoenzymes, but decreases further the impaired production of IL-2 in the T lymphocytes of SLE patients
    • COI: 1:CAS:528:DC%2BC2cXntFOlu7w%3D, PID: 23612780
    • Czifra G, Tóth B, Kovács I, Bíró T, Griger Z, Baráth S, Tarr T, Zeher M, Sipka S (2014) The in vitro treatment with vitamin D3 is ineffective on the expression of PKC isoenzymes, but decreases further the impaired production of IL-2 in the T lymphocytes of SLE patients. Rheumatol Int 34:717–720. doi:10.1007/s00296-013-2751-y
    • (2014) Rheumatol Int , vol.34 , pp. 717-720
    • Czifra, G.1    Tóth, B.2    Kovács, I.3    Bíró, T.4    Griger, Z.5    Baráth, S.6    Tarr, T.7    Zeher, M.8    Sipka, S.9
  • 108
    • 84872697123 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 downregulates aromatase expression and inflammatory cytokines in human macrophages
    • PID: 23253631
    • Villaggio B, Soldano S, Cutolo M (2012) 1,25-Dihydroxyvitamin D3 downregulates aromatase expression and inflammatory cytokines in human macrophages. Clin Exp Rheumatol 30:934–938
    • (2012) Clin Exp Rheumatol , vol.30 , pp. 934-938
    • Villaggio, B.1    Soldano, S.2    Cutolo, M.3
  • 109
    • 0037098411 scopus 로고    scopus 로고
    • Interleukin-2 is one of the targets of 1,25-dihydroxyvitamin D3 in the immune system
    • COI: 1:CAS:528:DC%2BD38XktlGqtr8%3D, PID: 12051670
    • Bemiss CJ, Mahon BD, Henry A, Weaver V, Cantorna MT (2002) Interleukin-2 is one of the targets of 1,25-dihydroxyvitamin D3 in the immune system. Arch Biochem Biophys 402:249–254. doi:10.1016/S0003-9861(02)00082-6
    • (2002) Arch Biochem Biophys , vol.402 , pp. 249-254
    • Bemiss, C.J.1    Mahon, B.D.2    Henry, A.3    Weaver, V.4    Cantorna, M.T.5
  • 110
    • 84898793327 scopus 로고    scopus 로고
    • Suppression of IL-10 production by calcitriol in patients with multiple sclerosis
    • COI: 1:CAS:528:DC%2BC2cXlt1CjtrY%3D, PID: 24694525
    • Niino M, Fukazawa T, Miyazaki Y, Takahashi E, Minami N, Amino I, Fujiki N, Doi S, Kikuchi S (2014) Suppression of IL-10 production by calcitriol in patients with multiple sclerosis. J Neuroimmunol 270:86–94. doi:10.1016/j.jneuroim.2014.03.011
    • (2014) J Neuroimmunol , vol.270 , pp. 86-94
    • Niino, M.1    Fukazawa, T.2    Miyazaki, Y.3    Takahashi, E.4    Minami, N.5    Amino, I.6    Fujiki, N.7    Doi, S.8    Kikuchi, S.9
  • 112
  • 114
    • 45949107446 scopus 로고    scopus 로고
    • Cutting edge: immunosuppressant as adjuvant for tolerogenic immunization
    • COI: 1:CAS:528:DC%2BD1cXkt1ars7s%3D, PID: 18390698
    • Kang Y, Xu L, Wang B, Chen A, Zheng G (2008) Cutting edge: immunosuppressant as adjuvant for tolerogenic immunization. J Immunol 180:5172–5176. doi:10.4049/jimmunol.180.8.5172
    • (2008) J Immunol , vol.180 , pp. 5172-5176
    • Kang, Y.1    Xu, L.2    Wang, B.3    Chen, A.4    Zheng, G.5
  • 115
    • 72949101620 scopus 로고    scopus 로고
    • FK506 as an adjuvant of tolerogenic DNA vaccination for the prevention of experimental autoimmune encephalomyelitis
    • COI: 1:CAS:528:DC%2BD1MXhsFCht7nO, PID: 19688809
    • Kang Y, Zhao J, Liu Y, Chen A, Zheng G, Yu Y, Mi J, Zou Q, Wang B (2009) FK506 as an adjuvant of tolerogenic DNA vaccination for the prevention of experimental autoimmune encephalomyelitis. J Gene Med 11:1064–1070. doi:10.1002/jgm.1387
    • (2009) J Gene Med , vol.11 , pp. 1064-1070
    • Kang, Y.1    Zhao, J.2    Liu, Y.3    Chen, A.4    Zheng, G.5    Yu, Y.6    Mi, J.7    Zou, Q.8    Wang, B.9
  • 116
    • 66949115028 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis in Lewis rats: IFN-beta acts as a tolerogenic adjuvant for induction of neuroantigen-dependent tolerance
    • COI: 1:CAS:528:DC%2BD1MXkslKisL0%3D, PID: 19380780
    • Mannie MD, Abbott DJ, Blanchfield JL (2009) Experimental autoimmune encephalomyelitis in Lewis rats: IFN-beta acts as a tolerogenic adjuvant for induction of neuroantigen-dependent tolerance. J Immunol 182:5331–5341. doi:10.4049/jimmunol.0803756
    • (2009) J Immunol , vol.182 , pp. 5331-5341
    • Mannie, M.D.1    Abbott, D.J.2    Blanchfield, J.L.3
  • 117
    • 84858795041 scopus 로고    scopus 로고
    • Current understanding of rheumatoid arthritis therapy
    • COI: 1:CAS:528:DC%2BC38XksVOktbs%3D, PID: 22357455
    • Colmegna I, Ohata BR, Menard HA (2012) Current understanding of rheumatoid arthritis therapy. Clin Pharmacol Ther 91:607–620. doi:10.1038/clpt.2011.325
    • (2012) Clin Pharmacol Ther , vol.91 , pp. 607-620
    • Colmegna, I.1    Ohata, B.R.2    Menard, H.A.3
  • 118
    • 73249142493 scopus 로고    scopus 로고
    • Antibodies to citrullinated proteins: molecular interactions and arthritogenicity
    • COI: 1:CAS:528:DC%2BC3cXjslartbk%3D, PID: 20192990
    • Uysal H, Nandakumar KS, Kessel C, Haag S, Carlsen S, Burkhardt H, Holmdahl R (2010) Antibodies to citrullinated proteins: molecular interactions and arthritogenicity. Immunol Rev 233:9–33. doi:10.1111/j.0105-2896.2009.00853.x
    • (2010) Immunol Rev , vol.233 , pp. 9-33
    • Uysal, H.1    Nandakumar, K.S.2    Kessel, C.3    Haag, S.4    Carlsen, S.5    Burkhardt, H.6    Holmdahl, R.7
  • 119
    • 77950238310 scopus 로고    scopus 로고
    • Autoantibodies in rheumatoid arthritis: rheumatoid factors and anti-citrullinated protein antibodies
    • COI: 1:CAS:528:DC%2BC3cXitlehu7g%3D, PID: 19926660
    • Song YW, Kang EH (2010) Autoantibodies in rheumatoid arthritis: rheumatoid factors and anti-citrullinated protein antibodies. QJM 103:139–46. doi:10.1093/qjmed/hcp165
    • (2010) QJM , vol.103 , pp. 139-146
    • Song, Y.W.1    Kang, E.H.2
  • 120
    • 0035119217 scopus 로고    scopus 로고
    • The immunologic homunculus in rheumatoid arthritis. A new viewpoint of immunopathogenesis in rheumatoid arthritis and therapeutic consequences
    • Bläss S, Engel JM, Burmester GR (2001) The immunologic homunculus in rheumatoid arthritis. A new viewpoint of immunopathogenesis in rheumatoid arthritis and therapeutic consequences. Z Rheumato 60:1–16. doi:10.1007/s003930170093
    • (2001) Z Rheumato , vol.60 , pp. 1-16
    • Bläss, S.1    Engel, J.M.2    Burmester, G.R.3
  • 121
    • 0034161714 scopus 로고    scopus 로고
    • 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation
    • COI: 1:CAS:528:DC%2BD3cXhsVKhsbw%3D, PID: 10679076
    • Penna G, Adorini L (2000) 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation. J Immunol 164:2405–2411. doi:10.4049/jimmunol.164.5.2405
    • (2000) J Immunol , vol.164 , pp. 2405-2411
    • Penna, G.1    Adorini, L.2
  • 122
    • 34548637038 scopus 로고    scopus 로고
    • Modulatory effects of 1,25-dihydroxyvitamin D3 on human B cell differentiation
    • COI: 1:CAS:528:DC%2BD2sXnvVyntbo%3D, PID: 17641030
    • Chen S, Sims GP, Chen XX, Gu YY, Chen S, Lipsky PE (2007) Modulatory effects of 1,25-dihydroxyvitamin D3 on human B cell differentiation. J Immunol 179:1634–1647. doi:10.4049/jimmunol.179.3.1634
    • (2007) J Immunol , vol.179 , pp. 1634-1647
    • Chen, S.1    Sims, G.P.2    Chen, X.X.3    Gu, Y.Y.4    Chen, S.5    Lipsky, P.E.6
  • 124
    • 74849095189 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 modulates Th17 polarization and interleukin-22 expression by memory T cells from patients with early rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BC3cXhtFGnurbI, PID: 20039421
    • Colin EM, Asmawidjaja PS, van Hamburg JP, Mus AM, van Driel M, Hazes JM, van Leeuwen JP, Lubberts E (2010) 1,25-Dihydroxyvitamin D3 modulates Th17 polarization and interleukin-22 expression by memory T cells from patients with early rheumatoid arthritis. Arthritis Rheum 62:132–142. doi:10.1002/art.25043
    • (2010) Arthritis Rheum , vol.62 , pp. 132-142
    • Colin, E.M.1    Asmawidjaja, P.S.2    van Hamburg, J.P.3    Mus, A.M.4    van Driel, M.5    Hazes, J.M.6    van Leeuwen, J.P.7    Lubberts, E.8
  • 125
    • 84940056402 scopus 로고    scopus 로고
    • Vitamin D antagonizes the suppressive effect of inflammatory cytokines on CTLA-4 expression and regulatory function
    • PID: 26134669
    • Jeffery LE, Qureshi OS, Gardner D, Hou TZ, Briggs Z, Soskic B, Baker J, Raza K, Sansom DM (2015) Vitamin D antagonizes the suppressive effect of inflammatory cytokines on CTLA-4 expression and regulatory function. PLoS One 10:e0131539. doi:10.1371/journal.pone.0131539
    • (2015) PLoS One , vol.10
    • Jeffery, L.E.1    Qureshi, O.S.2    Gardner, D.3    Hou, T.Z.4    Briggs, Z.5    Soskic, B.6    Baker, J.7    Raza, K.8    Sansom, D.M.9
  • 126
    • 84859038758 scopus 로고    scopus 로고
    • The vitamin D receptor regulates rheumatoid arthritis synovial fibroblast invasion and morphology
    • COI: 1:CAS:528:DC%2BC38XovFeksbo%3D, PID: 22064970
    • Laragione T, Shah A, Gulko PS (2012) The vitamin D receptor regulates rheumatoid arthritis synovial fibroblast invasion and morphology. Mol Med 18:194–200. doi:10.2119/molmed.2011.00410
    • (2012) Mol Med , vol.18 , pp. 194-200
    • Laragione, T.1    Shah, A.2    Gulko, P.S.3
  • 127
    • 84890087335 scopus 로고    scopus 로고
    • Modulatory effect of 1,25-dihydroxyvitamin D3 on IL1 β -induced RANKL, OPG, TNF α, and IL-6 expression in human rheumatoid synoviocyte MH7A
    • PID: 24348674
    • Feng X, Lv C, Wang F, Gan K, Zhang M, Tan W (2013) Modulatory effect of 1,25-dihydroxyvitamin D3 on IL1 β -induced RANKL, OPG, TNF α, and IL-6 expression in human rheumatoid synoviocyte MH7A. Clin Dev Immunol 2013:160123. doi:10.1155/2013/160123
    • (2013) Clin Dev Immunol , vol.2013 , pp. 160123
    • Feng, X.1    Lv, C.2    Wang, F.3    Gan, K.4    Zhang, M.5    Tan, W.6
  • 128
    • 0033281623 scopus 로고    scopus 로고
    • The effects of 1 alpha,25-dihydroxyvitamin D(3) on matrix metalloproteinase and prostaglandin E(2) production by cells of the rheumatoid lesion
    • COI: 1:CAS:528:DC%2BD3cXlslOqtb8%3D, PID: 11056661
    • Tetlow LC, Woolley DE (1999) The effects of 1 alpha,25-dihydroxyvitamin D(3) on matrix metalloproteinase and prostaglandin E(2) production by cells of the rheumatoid lesion. Arthritis Res 1:63–70. doi:10.1186/ar12
    • (1999) Arthritis Res , vol.1 , pp. 63-70
    • Tetlow, L.C.1    Woolley, D.E.2
  • 129
    • 84878352012 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 inhibits directly human osteoclastogenesis by down-regulation of the c-Fms and RANK expression
    • COI: 1:CAS:528:DC%2BC38XhsF2hsbzE, PID: 23116709
    • Kim TH, Lee B, Kwon E, Choi CH, Sung IH, Kim Y, Sohn J, Ji JD (2013) 1,25-Dihydroxyvitamin D3 inhibits directly human osteoclastogenesis by down-regulation of the c-Fms and RANK expression. Joint Bone Spine 80:307–314. doi:10.1016/j.jbspin.2012.09.011
    • (2013) Joint Bone Spine , vol.80 , pp. 307-314
    • Kim, T.H.1    Lee, B.2    Kwon, E.3    Choi, C.H.4    Sung, I.H.5    Kim, Y.6    Sohn, J.7    Ji, J.D.8


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