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Volumn 19, Issue 4, 2013, Pages 269-277

Vitamin D3 induces IDO+ tolerogenic DCs and enhances treg, reducing the severity of EAE

Author keywords

Autoimmunity; DCs; T cell activation; Tregs; Vitamin D3

Indexed keywords

COLECALCIFEROL;

EID: 84875616786     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/cns.12071     Document Type: Article
Times cited : (117)

References (42)
  • 2
    • 0034906607 scopus 로고    scopus 로고
    • Regional variation in multiple sclerosis prevalence in Australia and its association with ambient ultraviolet radiation
    • van der Mei IA, Ponsonby AL, Blizzard L, Dwyer T. Regional variation in multiple sclerosis prevalence in Australia and its association with ambient ultraviolet radiation. Neuroepidemiology 2001;20:168-174.
    • (2001) Neuroepidemiology , vol.20 , pp. 168-174
    • van der Mei, I.A.1    Ponsonby, A.L.2    Blizzard, L.3    Dwyer, T.4
  • 3
    • 0346688789 scopus 로고    scopus 로고
    • Multiple sclerosis in US veterans of the Vietnam era and later military service: Race, sex, and geography
    • Wallin MT, Page WF, Kurtzke JF. Multiple sclerosis in US veterans of the Vietnam era and later military service: Race, sex, and geography. Ann Neurol 2004;55:65-71.
    • (2004) Ann Neurol , vol.55 , pp. 65-71
    • Wallin, M.T.1    Page, W.F.2    Kurtzke, J.F.3
  • 4
    • 0029821239 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis
    • Cantorna MT, Hayes CE, DeLuca HF. 1, 25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis. Proc Natl Acad Sci U S A 1996;93:7861-7864.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 7861-7864
    • Cantorna, M.T.1    Hayes, C.E.2    DeLuca, H.F.3
  • 5
    • 24744443699 scopus 로고    scopus 로고
    • Vitamin D3 confers protection from autoimmune encephalomyelitis only in female mice
    • Spach KM, Hayes CE. Vitamin D3 confers protection from autoimmune encephalomyelitis only in female mice. J Immunol 2005;175:4119-4126.
    • (2005) J Immunol , vol.175 , pp. 4119-4126
    • Spach, K.M.1    Hayes, C.E.2
  • 6
    • 65249109297 scopus 로고    scopus 로고
    • Enhancement of 1,25-dihydroxyvitamin D3-mediated suppression of experimental autoimmune encephalomyelitis by calcitonin
    • Becklund BR, Hansen DW Jr, Deluca HF. Enhancement of 1, 25-dihydroxyvitamin D3-mediated suppression of experimental autoimmune encephalomyelitis by calcitonin. Proc Natl Acad Sci U S A 2009;106:5276-5281.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 5276-5281
    • Becklund, B.R.1    Hansen Jr, D.W.2    Deluca, H.F.3
  • 7
    • 0027941138 scopus 로고
    • Oral tolerance to myelin basic protein induces regulatory TGF-beta-secreting T cells in Peyer's patches of SJL mice
    • Santos LM, al-Sabbagh A, Londono A, Weiner HL. Oral tolerance to myelin basic protein induces regulatory TGF-beta-secreting T cells in Peyer's patches of SJL mice. Cell Immunol 1994;157:439-447.
    • (1994) Cell Immunol , vol.157 , pp. 439-447
    • Santos, L.M.1    al-Sabbagh, A.2    Londono, A.3    Weiner, H.L.4
  • 8
    • 84868195009 scopus 로고    scopus 로고
    • Fasudil ameliorates disease progression in experimental autoimmune encephalomyelitis, acting possibly through antiinflammatory effect
    • Hou SW, Liu CY, Li YH, et al. Fasudil ameliorates disease progression in experimental autoimmune encephalomyelitis, acting possibly through antiinflammatory effect. CNS Neurosci Ther 2012;18:909-917.
    • (2012) CNS Neurosci Ther , vol.18 , pp. 909-917
    • Hou, S.W.1    Liu, C.Y.2    Li, Y.H.3
  • 9
    • 33750314525 scopus 로고    scopus 로고
    • IL-10 signaling is essential for 1,25-dihydroxyvitamin D3-mediated inhibition of experimental autoimmune encephalomyelitis
    • Spach KM, Nashold FE, Dittel BN, Hayes CE. IL-10 signaling is essential for 1, 25-dihydroxyvitamin D3-mediated inhibition of experimental autoimmune encephalomyelitis. J Immunol 2006;177:6030-6037.
    • (2006) J Immunol , vol.177 , pp. 6030-6037
    • Spach, K.M.1    Nashold, F.E.2    Dittel, B.N.3    Hayes, C.E.4
  • 10
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli E, Carrier Y, Gao W, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006;441:235-238.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3
  • 11
    • 13244283212 scopus 로고    scopus 로고
    • IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
    • Langrish CL, Chen Y, Blumenschein WM, et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005;201:233-240.
    • (2005) J Exp Med , vol.201 , pp. 233-240
    • Langrish, C.L.1    Chen, Y.2    Blumenschein, W.M.3
  • 12
    • 27544465354 scopus 로고    scopus 로고
    • A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
    • Park H, Li Z, Yang XO, et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 2005;6:1133-1141.
    • (2005) Nat Immunol , vol.6 , pp. 1133-1141
    • Park, H.1    Li, Z.2    Yang, X.O.3
  • 13
    • 56149125346 scopus 로고    scopus 로고
    • Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis
    • O'Connor RA, Prendergast CT, Sabatos CA, et al. Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis. J Immunol 2008;181:3750-3754.
    • (2008) J Immunol , vol.181 , pp. 3750-3754
    • O'Connor, R.A.1    Prendergast, C.T.2    Sabatos, C.A.3
  • 14
    • 33646339134 scopus 로고    scopus 로고
    • 1,25 Dihydroxyvitamin-D3 modulates JAK-STAT pathway in IL-12/IFNgamma axis leading to Th1 response in experimental allergic encephalomyelitis
    • Muthian G, Raikwar HP, Rajasingh J, Bright JJ. 1, 25 Dihydroxyvitamin-D3 modulates JAK-STAT pathway in IL-12/IFNgamma axis leading to Th1 response in experimental allergic encephalomyelitis. J Neurosci Res 2006;83:1299-1309.
    • (2006) J Neurosci Res , vol.83 , pp. 1299-1309
    • Muthian, G.1    Raikwar, H.P.2    Rajasingh, J.3    Bright, J.J.4
  • 15
    • 65249120937 scopus 로고    scopus 로고
    • Calcitriol suppresses antiretinal autoimmunity through inhibitory effects on the Th17 effector response
    • Tang J, Zhou R, Luger D, et al. Calcitriol suppresses antiretinal autoimmunity through inhibitory effects on the Th17 effector response. J Immunol 2009;182:4624-4632.
    • (2009) J Immunol , vol.182 , pp. 4624-4632
    • Tang, J.1    Zhou, R.2    Luger, D.3
  • 16
    • 65049086842 scopus 로고    scopus 로고
    • Dendritic cell tolerogenicity: A key mechanism in immunomodulation by vitamin D receptor agonists
    • Adorini L, Penna G. Dendritic cell tolerogenicity: A key mechanism in immunomodulation by vitamin D receptor agonists. Hum Immunol 2009;70:345-352.
    • (2009) Hum Immunol , vol.70 , pp. 345-352
    • Adorini, L.1    Penna, G.2
  • 17
    • 50249179101 scopus 로고    scopus 로고
    • Vitamin effects on the immune system: Vitamins A and D take centre stage
    • Mora JR, Iwata M, von Andrian UH. Vitamin effects on the immune system: Vitamins A and D take centre stage. Nat Rev Immunol 2008;8:685-698.
    • (2008) Nat Rev Immunol , vol.8 , pp. 685-698
    • Mora, J.R.1    Iwata, M.2    von Andrian, U.H.3
  • 18
    • 0038189866 scopus 로고    scopus 로고
    • Differential regulation of vitamin D receptor and its ligand in human monocyte-derived dendritic cells
    • Hewison M, Freeman L, Hughes SV, et al. Differential regulation of vitamin D receptor and its ligand in human monocyte-derived dendritic cells. J Immunol 2003;170:5382-5390.
    • (2003) J Immunol , vol.170 , pp. 5382-5390
    • Hewison, M.1    Freeman, L.2    Hughes, S.V.3
  • 19
    • 0034178251 scopus 로고    scopus 로고
    • Vitamin D3 affects differentiation, maturation, and function of human monocyte-derived dendritic cells
    • Piemonti L, Monti P, Sironi M, et al. Vitamin D3 affects differentiation, maturation, and function of human monocyte-derived dendritic cells. J Immunol 2000;164:4443-4451.
    • (2000) J Immunol , vol.164 , pp. 4443-4451
    • Piemonti, L.1    Monti, P.2    Sironi, M.3
  • 20
    • 61449181171 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype
    • Szeles L, Keresztes G, Torocsik D, et al. 1, 25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype. J Immunol 2009;182:2074-2083.
    • (2009) J Immunol , vol.182 , pp. 2074-2083
    • Szeles, L.1    Keresztes, G.2    Torocsik, D.3
  • 21
    • 81255185227 scopus 로고    scopus 로고
    • Vitamin D-mediated immune regulation in multiple sclerosis
    • Correale J, Ysrraelit MC, Gaitan MI. Vitamin D-mediated immune regulation in multiple sclerosis. J Neurol Sci 2011;311:23-31.
    • (2011) J Neurol Sci , vol.311 , pp. 23-31
    • Correale, J.1    Ysrraelit, M.C.2    Gaitan, M.I.3
  • 22
    • 39449126502 scopus 로고    scopus 로고
    • The Foxp3 +  regulatory T cell: A jack of all trades, master of regulation
    • Tang Q, Bluestone JA. The Foxp3 +  regulatory T cell: A jack of all trades, master of regulation. Nat Immunol 2008;9:239-244.
    • (2008) Nat Immunol , vol.9 , pp. 239-244
    • Tang, Q.1    Bluestone, J.A.2
  • 23
    • 36248970701 scopus 로고    scopus 로고
    • A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells
    • Awasthi A, Carrier Y, Peron JP, et al. A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells. Nat Immunol 2007;8:1380-1389.
    • (2007) Nat Immunol , vol.8 , pp. 1380-1389
    • Awasthi, A.1    Carrier, Y.2    Peron, J.P.3
  • 24
    • 33845942398 scopus 로고    scopus 로고
    • Th3 cells in peripheral tolerance. II. TGF-beta-transgenic Th3 cells rescue IL-2-deficient mice from autoimmunity
    • Carrier Y, Yuan J, Kuchroo VK, Weiner HL. Th3 cells in peripheral tolerance. II. TGF-beta-transgenic Th3 cells rescue IL-2-deficient mice from autoimmunity. J Immunol 2007;178:172-178.
    • (2007) J Immunol , vol.178 , pp. 172-178
    • Carrier, Y.1    Yuan, J.2    Kuchroo, V.K.3    Weiner, H.L.4
  • 25
    • 33746342994 scopus 로고    scopus 로고
    • Foxp3 +  CD25 +  CD4 +  natural regulatory T cells in dominant self-tolerance and autoimmune disease
    • Sakaguchi S, Ono M, Setoguchi R, et al. Foxp3 +  CD25 +  CD4 +  natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol Rev 2006;212:8-27.
    • (2006) Immunol Rev , vol.212 , pp. 8-27
    • Sakaguchi, S.1    Ono, M.2    Setoguchi, R.3
  • 26
    • 43249128068 scopus 로고    scopus 로고
    • Regulatory T cells in the control of inflammatory demyelinating diseases of the central nervous system
    • Anderton SM, Liblau RS. Regulatory T cells in the control of inflammatory demyelinating diseases of the central nervous system. Curr Opin Neurol 2008;21:248-254.
    • (2008) Curr Opin Neurol , vol.21 , pp. 248-254
    • Anderton, S.M.1    Liblau, R.S.2
  • 27
    • 37849027594 scopus 로고    scopus 로고
    • Foxp3 +  regulatory T cells in the control of experimental CNS autoimmune disease
    • O'Connor RA, Anderton SM. Foxp3 +  regulatory T cells in the control of experimental CNS autoimmune disease. J Neuroimmunol 2008;193:1-11.
    • (2008) J Neuroimmunol , vol.193 , pp. 1-11
    • O'Connor, R.A.1    Anderton, S.M.2
  • 28
    • 56649106476 scopus 로고    scopus 로고
    • Interplay between effector Th17 and regulatory T cells
    • Awasthi A, Murugaiyan G, Kuchroo VK. Interplay between effector Th17 and regulatory T cells. J Clin Immunol 2008;28:660-670.
    • (2008) J Clin Immunol , vol.28 , pp. 660-670
    • Awasthi, A.1    Murugaiyan, G.2    Kuchroo, V.K.3
  • 29
    • 0037018104 scopus 로고    scopus 로고
    • In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
    • Barrat FJ, Cua DJ, Boonstra A, et al. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med 2002;195:603-616.
    • (2002) J Exp Med , vol.195 , pp. 603-616
    • Barrat, F.J.1    Cua, D.J.2    Boonstra, A.3
  • 31
    • 27744595600 scopus 로고    scopus 로고
    • Expression of the inhibitory receptor ILT3 on dendritic cells is dispensable for induction of CD4(+)Foxp3(+) regulatory T cells by 1,25-dihydroxyvitamin D-3
    • Penna G, Roncari A, Amuchastegui S, et al. Expression of the inhibitory receptor ILT3 on dendritic cells is dispensable for induction of CD4(+)Foxp3(+) regulatory T cells by 1, 25-dihydroxyvitamin D-3. Blood 2005;106:3490-3497.
    • (2005) Blood , vol.106 , pp. 3490-3497
    • Penna, G.1    Roncari, A.2    Amuchastegui, S.3
  • 32
    • 84865557050 scopus 로고    scopus 로고
    • Proteome analysis of spinal cord during the clinical course of monophasic experimental autoimmune encephalomyelitis
    • Farias AS, Martins-de-Souza D, Guimaraes L, et al. Proteome analysis of spinal cord during the clinical course of monophasic experimental autoimmune encephalomyelitis. Proteomics 2012;12:2656-2662.
    • (2012) Proteomics , vol.12 , pp. 2656-2662
    • Farias, A.S.1    Martins-de-Souza, D.2    Guimaraes, L.3
  • 33
    • 79953056711 scopus 로고    scopus 로고
    • Regulatory T cell induction during Plasmodium chabaudi infection modifies the clinical course of experimental autoimmune encephalomyelitis
    • Farias AS, Talaisys RL, Blanco YC, et al. Regulatory T cell induction during Plasmodium chabaudi infection modifies the clinical course of experimental autoimmune encephalomyelitis. PLoS ONE 2011;6:e17849.
    • (2011) PLoS ONE , vol.6
    • Farias, A.S.1    Talaisys, R.L.2    Blanco, Y.C.3
  • 34
    • 0041931076 scopus 로고    scopus 로고
    • Foxp3 and natural regulatory T cells: Key to a cell lineage?
    • Ramsdell F. Foxp3 and natural regulatory T cells: Key to a cell lineage? Immunity 2003;19:165-168.
    • (2003) Immunity , vol.19 , pp. 165-168
    • Ramsdell, F.1
  • 35
    • 84855370788 scopus 로고    scopus 로고
    • IDO and regulatory T cell support are critical for cytotoxic T lymphocyte-associated Ag-4 Ig-mediated long-term solid organ allograft survival
    • Sucher R, Fischler K, Oberhuber R, et al. IDO and regulatory T cell support are critical for cytotoxic T lymphocyte-associated Ag-4 Ig-mediated long-term solid organ allograft survival. J Immunol 2012;188:37-46.
    • (2012) J Immunol , vol.188 , pp. 37-46
    • Sucher, R.1    Fischler, K.2    Oberhuber, R.3
  • 36
    • 80054756076 scopus 로고    scopus 로고
    • Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation
    • O'Sullivan BJ, Pai S, Street S, et al. Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation. J Immunol 2011;187:4018-4030.
    • (2011) J Immunol , vol.187 , pp. 4018-4030
    • O'Sullivan, B.J.1    Pai, S.2    Street, S.3
  • 37
    • 70349737858 scopus 로고    scopus 로고
    • Cutting edge: Negative regulation of dendritic cells through acetylation of the nonhistone protein STAT-3
    • Sun Y, Chin YE, Weisiger E, et al. Cutting edge: Negative regulation of dendritic cells through acetylation of the nonhistone protein STAT-3. J Immunol 2009;182:5899-5903.
    • (2009) J Immunol , vol.182 , pp. 5899-5903
    • Sun, Y.1    Chin, Y.E.2    Weisiger, E.3
  • 38
    • 33845911207 scopus 로고    scopus 로고
    • Vitamin D3-mediated alterations to myeloid dendritic cell trafficking in vivo expand the scope of their antigen presenting properties
    • Enioutina EY, Bareyan D, Daynes RA. Vitamin D3-mediated alterations to myeloid dendritic cell trafficking in vivo expand the scope of their antigen presenting properties. Vaccine 2007;25:1236-1249.
    • (2007) Vaccine , vol.25 , pp. 1236-1249
    • Enioutina, E.Y.1    Bareyan, D.2    Daynes, R.A.3
  • 39
    • 80052020183 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells
    • Pallotta MT, Orabona C, Volpi C, et al. Indoleamine 2, 3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells. Nat Immunol 2011;12:870-878.
    • (2011) Nat Immunol , vol.12 , pp. 870-878
    • Pallotta, M.T.1    Orabona, C.2    Volpi, C.3
  • 40
  • 41
    • 80052016154 scopus 로고    scopus 로고
    • IDO: More than an enzyme
    • Chen W. IDO: More than an enzyme. Nat Immunol 2011;12:809-811.
    • (2011) Nat Immunol , vol.12 , pp. 809-811
    • Chen, W.1
  • 42
    • 67349275439 scopus 로고    scopus 로고
    • The relevance of vitamin D receptor gene polymorphisms for vitamin D research in multiple sclerosis
    • Smolders J, Peelen E, Thewissen M, et al. The relevance of vitamin D receptor gene polymorphisms for vitamin D research in multiple sclerosis. Autoimmun Rev 2009;8:621-626.
    • (2009) Autoimmun Rev , vol.8 , pp. 621-626
    • Smolders, J.1    Peelen, E.2    Thewissen, M.3


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