메뉴 건너뛰기




Volumn 37, Issue 4, 2016, Pages 572-577

Middle East Respiratory Syndrome Virus Pathogenesis

Author keywords

coronavirus; MERS CoV; SARS CoV

Indexed keywords

ANTIVIRUS AGENT; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 23; VIRUS RNA;

EID: 84982711427     PISSN: 10693424     EISSN: 10989048     Source Type: Journal    
DOI: 10.1055/s-0036-1584796     Document Type: Article
Times cited : (55)

References (75)
  • 1
    • 19944427959 scopus 로고    scopus 로고
    • Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia
    • Woo P. C., Lau S. K., Chu C. M., et al. Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia. J Virol: 2005; 79 2 884 895
    • (2005) J Virol , vol.79 , Issue.2 , pp. 884-895
    • Woo, P.C.1    Lau, S.K.2    Chu, C.M.3
  • 2
    • 85016626167 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus: Transmission, virology and therapeutic targeting to aid in outbreak control
    • Durai P., Batool M., Shah M., Choi S. Middle East respiratory syndrome coronavirus: transmission, virology and therapeutic targeting to aid in outbreak control. Exp Mol Med: 2015; 47 e181
    • (2015) Exp Mol Med , vol.47 , pp. e181
    • Durai, P.1    Batool, M.2    Shah, M.3    Choi, S.4
  • 3
    • 29144451985 scopus 로고    scopus 로고
    • Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus
    • Weiss S. R., Navas-Martin S. Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus. Microbiol Mol Biol Rev: 2005; 69 4 635 664
    • (2005) Microbiol Mol Biol Rev , vol.69 , Issue.4 , pp. 635-664
    • Weiss, S.R.1    Navas-Martin, S.2
  • 4
    • 1942533454 scopus 로고    scopus 로고
    • A previously undescribed coronavirus associated with respiratory disease in humans
    • Fouchier R. A., Hartwig N. G., Bestebroer T. M., et al. A previously undescribed coronavirus associated with respiratory disease in humans. Proc Natl Acad Sci U S A: 2004; 101 16 6212 6216
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.16 , pp. 6212-6216
    • Fouchier, R.A.1    Hartwig, N.G.2    Bestebroer, T.M.3
  • 5
    • 84917706604 scopus 로고    scopus 로고
    • Pathogenesis of Middle East respiratory syndrome coronavirus
    • van den Brand J. M., Smits S. L., Haagmans B. L. Pathogenesis of Middle East respiratory syndrome coronavirus. J Pathol: 2015; 235 2 175 184
    • (2015) J Pathol , vol.235 , Issue.2 , pp. 175-184
    • Van Den Brand, J.M.1    Smits, S.L.2    Haagmans, B.L.3
  • 6
    • 77955451060 scopus 로고    scopus 로고
    • Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method
    • Gaunt E. R., Hardie A., Claas E. C., Simmonds P., Templeton K. E. Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method. J Clin Microbiol: 2010; 48 8 2940 2947
    • (2010) J Clin Microbiol , vol.48 , Issue.8 , pp. 2940-2947
    • Gaunt, E.R.1    Hardie, A.2    Claas, E.C.3    Simmonds, P.4    Templeton, K.E.5
  • 7
    • 84941025094 scopus 로고    scopus 로고
    • New coronavirus outbreak. Lessons learned from the severe acute respiratory syndrome epidemic
    • Álvarez E., Donado-Campos J., Morilla F. New coronavirus outbreak. Lessons learned from the severe acute respiratory syndrome epidemic. Epidemiol Infect: 2015; 143 13 2882 2893
    • (2015) Epidemiol Infect , vol.143 , Issue.13 , pp. 2882-2893
    • Álvarez, E.1    Donado-Campos, J.2    Morilla, F.3
  • 8
    • 84919663444 scopus 로고    scopus 로고
    • Emergence of MERS-CoV in the Middle East: Origins, transmission, treatment, and perspectives
    • Sharif-Yakan A., Kanj S. S. Emergence of MERS-CoV in the Middle East: origins, transmission, treatment, and perspectives. PLoS Pathog: 2014; 10 12 e1004457
    • (2014) PLoS Pathog , vol.10 , Issue.12 , pp. e1004457
    • Sharif-Yakan, A.1    Kanj, S.S.2
  • 9
    • 84875213690 scopus 로고    scopus 로고
    • Genetic relatedness of the novel human group C betacoronavirus to Tylonycteris bat coronavirus HKU4 and Pipistrellus bat coronavirus HKU5
    • Woo P. C., Lau S. K., Li K. S., Tsang A. K., Yuen K. Y. Genetic relatedness of the novel human group C betacoronavirus to Tylonycteris bat coronavirus HKU4 and Pipistrellus bat coronavirus HKU5. Emerg Microbes Infect: 2012; 1 11 e35
    • (2012) Emerg Microbes Infect , vol.1 , Issue.11 , pp. e35
    • Woo, P.C.1    Lau, S.K.2    Li, K.S.3    Tsang, A.K.4    Yuen, K.Y.5
  • 10
    • 84878966726 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus (MERS-CoV): Announcement of the Coronavirus Study Group
    • de Groot R. J., Baker S. C., Baric R. S., et al. Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group. J Virol: 2013; 87 14 7790 7792
    • (2013) J Virol , vol.87 , Issue.14 , pp. 7790-7792
    • De Groot, R.J.1    Baker, S.C.2    Baric, R.S.3
  • 11
    • 33745784140 scopus 로고    scopus 로고
    • Molecular diversity of coronaviruses in bats
    • Woo P. C., Lau S. K., Li K. S., et al. Molecular diversity of coronaviruses in bats. Virology: 2006; 351 1 180 187
    • (2006) Virology , vol.351 , Issue.1 , pp. 180-187
    • Woo, P.C.1    Lau, S.K.2    Li, K.S.3
  • 12
    • 79952118016 scopus 로고    scopus 로고
    • Circulation of group 2 coronaviruses in a bat species common to urban areas in Western Europe
    • Reusken C. B., Lina P. H., Pielaat A., et al. Circulation of group 2 coronaviruses in a bat species common to urban areas in Western Europe. Vector Borne Zoonotic Dis: 2010; 10 8 785 791
    • (2010) Vector Borne Zoonotic Dis , vol.10 , Issue.8 , pp. 785-791
    • Reusken, C.B.1    Lina, P.H.2    Pielaat, A.3
  • 13
    • 84871415482 scopus 로고    scopus 로고
    • Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans
    • van Boheemen S., de Graaf M., Lauber C., et al. Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans. MBio: 2012; 3 6 473 512
    • (2012) MBio , vol.3 , Issue.6 , pp. 473-512
    • Van Boheemen, S.1    De Graaf, M.2    Lauber, C.3
  • 14
    • 84884228611 scopus 로고    scopus 로고
    • Close relative of human Middle East respiratory syndrome coronavirus in bat, South Africa
    • Ithete N. L., Stoffberg S., Corman V. M., et al. Close relative of human Middle East respiratory syndrome coronavirus in bat, South Africa. Emerg Infect Dis: 2013; 19 10 1697 1699
    • (2013) Emerg Infect Dis , vol.19 , Issue.10 , pp. 1697-1699
    • Ithete, N.L.1    Stoffberg, S.2    Corman, V.M.3
  • 15
    • 84892538696 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus in dromedary camels: An outbreak investigation
    • Haagmans B. L., Al Dhahiry S. H., Reusken C. B., et al. Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation. Lancet Infect Dis: 2014; 14 2 140 145
    • (2014) Lancet Infect Dis , vol.14 , Issue.2 , pp. 140-145
    • Haagmans, B.L.1    Al Dhahiry, S.H.2    Reusken, C.B.3
  • 16
    • 84939466737 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus MERS-CoV: Current knowledge gaps
    • Banik G. R., Khandaker G., Rashid H. Middle East respiratory syndrome coronavirus MERS-CoV: current knowledge gaps. Paediatr Respir Rev: 2015; 16 3 197 202
    • (2015) Paediatr Respir Rev , vol.16 , Issue.3 , pp. 197-202
    • Banik, G.R.1    Khandaker, G.2    Rashid, H.3
  • 17
    • 84884377173 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: A comparative serological study
    • Reusken C. B., Haagmans B. L., Müller M. A., et al. Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study. Lancet Infect Dis: 2013; 13 10 859 866
    • (2013) Lancet Infect Dis , vol.13 , Issue.10 , pp. 859-866
    • Reusken, C.B.1    Haagmans, B.L.2    Müller, M.A.3
  • 18
    • 84884232066 scopus 로고    scopus 로고
    • Seroepidemiology for MERS coronavirus using microneutralisation and pseudoparticle virus neutralisation assays reveal a high prevalence of antibody in dromedary camels in Egypt, June 2013
    • Perera R. A., Wang P., Gomaa M. R., et al. Seroepidemiology for MERS coronavirus using microneutralisation and pseudoparticle virus neutralisation assays reveal a high prevalence of antibody in dromedary camels in Egypt, June 2013. Euro Surveill: 2013; 18 36 20574
    • (2013) Euro Surveill , vol.18 , Issue.36 , pp. 20574
    • Perera, R.A.1    Wang, P.2    Gomaa, M.R.3
  • 19
    • 84902255360 scopus 로고    scopus 로고
    • Stability of Middle East respiratory syndrome coronavirus in milk
    • van Doremalen N., Bushmaker T., Karesh W. B., Munster V. J. Stability of Middle East respiratory syndrome coronavirus in milk. Emerg Infect Dis: 2014; 20 7 1263 1264
    • (2014) Emerg Infect Dis , vol.20 , Issue.7 , pp. 1263-1264
    • Van Doremalen, N.1    Bushmaker, T.2    Karesh, W.B.3    Munster, V.J.4
  • 20
    • 84908250862 scopus 로고    scopus 로고
    • Reply to Concerns about misinterpretation of recent scientific data implicating dromedary camels in epidemiology of Middle East respiratory syndrome (MERS)
    • Alagaili A. N., Briese T., Karesh W. B., Daszak P., Lipkin W. I. Reply to Concerns about misinterpretation of recent scientific data implicating dromedary camels in epidemiology of Middle East respiratory syndrome (MERS) MBio: 2014; 5 4 e01482 e14
    • (2014) MBio , vol.5 , Issue.4 , pp. e14-e01482
    • Alagaili, A.N.1    Briese, T.2    Karesh, W.B.3    Daszak, P.4    Lipkin, W.I.5
  • 21
    • 84903435220 scopus 로고    scopus 로고
    • Evidence for camel-to-human transmission of MERS coronavirus
    • Azhar E. I., El-Kafrawy S. A., Farraj S. A., et al. Evidence for camel-to-human transmission of MERS coronavirus. N Engl J Med: 2014; 370 26 2499 2505
    • (2014) N Engl J Med , vol.370 , Issue.26 , pp. 2499-2505
    • Azhar, E.I.1    El-Kafrawy, S.A.2    Farraj, S.A.3
  • 22
    • 33745802348 scopus 로고    scopus 로고
    • Evolutionary history of the closely related group 2 coronaviruses: Porcine hemagglutinating encephalomyelitis virus, bovine coronavirus, and human coronavirus OC43
    • Vijgen L., Keyaerts E., Lemey P., et al. Evolutionary history of the closely related group 2 coronaviruses: porcine hemagglutinating encephalomyelitis virus, bovine coronavirus, and human coronavirus OC43. J Virol: 2006; 80 14 7270 7274
    • (2006) J Virol , vol.80 , Issue.14 , pp. 7270-7274
    • Vijgen, L.1    Keyaerts, E.2    Lemey, P.3
  • 23
    • 84891828929 scopus 로고    scopus 로고
    • MERS coronavirus: Data gaps for laboratory preparedness
    • de Sousa R., Reusken C., Koopmans M. MERS coronavirus: data gaps for laboratory preparedness. J Clin Virol: 2014; 59 1 4 11
    • (2014) J Clin Virol , vol.59 , Issue.1 , pp. 4-11
    • De Sousa, R.1    Reusken, C.2    Koopmans, M.3
  • 24
    • 84880088201 scopus 로고    scopus 로고
    • Hospital outbreak of Middle East respiratory syndrome coronavirus
    • KSA MERS-CoV Investigation Team
    • Assiri A., McGeer A., Perl T. M., et al. KSA MERS-CoV Investigation Team. Hospital outbreak of Middle East respiratory syndrome coronavirus. N Engl J Med: 2013; 369 5 407 416
    • (2013) N Engl J Med , vol.369 , Issue.5 , pp. 407-416
    • Assiri, A.1    McGeer, A.2    Perl, T.M.3
  • 26
    • 84896534867 scopus 로고    scopus 로고
    • Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection
    • Arabi Y. M., Arifi A. A., Balkhy H. H., et al. Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection. Ann Intern Med: 2014; 160 6 389 397
    • (2014) Ann Intern Med , vol.160 , Issue.6 , pp. 389-397
    • Arabi, Y.M.1    Arifi, A.A.2    Balkhy, H.H.3
  • 27
    • 84882598788 scopus 로고    scopus 로고
    • Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: A descriptive study
    • Assiri A., Al-Tawfiq J. A., Al-Rabeeah A. A., et al. Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. Lancet Infect Dis: 2013; 13 9 752 761
    • (2013) Lancet Infect Dis , vol.13 , Issue.9 , pp. 752-761
    • Assiri, A.1    Al-Tawfiq, J.A.2    Al-Rabeeah, A.A.3
  • 28
    • 84901003129 scopus 로고    scopus 로고
    • Current advancements and potential strategies in the development of MERS-CoV vaccines
    • Zhang N., Jiang S., Du L. Current advancements and potential strategies in the development of MERS-CoV vaccines. Expert Rev Vaccines: 2014; 13 6 761 774
    • (2014) Expert Rev Vaccines , vol.13 , Issue.6 , pp. 761-774
    • Zhang, N.1    Jiang, S.2    Du, L.3
  • 29
    • 84939231634 scopus 로고    scopus 로고
    • Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS for nsp5 REGULATION and the DEVELOPMENT of ANTIVIRALS
    • Tomar S., Johnston M. L., St John S. E., et al. Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS. J Biol Chem: 2015; 290 32 19403 19422
    • (2015) J Biol Chem , vol.290 , Issue.32 , pp. 19403-19422
    • Tomar, S.1    Johnston, M.L.2    St John, S.E.3
  • 30
    • 84918528852 scopus 로고    scopus 로고
    • Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression
    • Bailey-Elkin B. A., Knaap R. C., Johnson G. G., et al. Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression. J Biol Chem: 2014; 289 50 34667 34682
    • (2014) J Biol Chem , vol.289 , Issue.50 , pp. 34667-34682
    • Bailey-Elkin, B.A.1    Knaap, R.C.2    Johnson, G.G.3
  • 31
    • 67349158649 scopus 로고    scopus 로고
    • Coronaviruses post-SARS: Update on replication and pathogenesis
    • Perlman S., Netland J. Coronaviruses post-SARS: update on replication and pathogenesis. Nat Rev Microbiol: 2009; 7 6 439 450
    • (2009) Nat Rev Microbiol , vol.7 , Issue.6 , pp. 439-450
    • Perlman, S.1    Netland, J.2
  • 32
    • 84941413167 scopus 로고    scopus 로고
    • Middle East respiratory syndrome
    • Zumla A., Hui D. S., Perlman S. Middle East respiratory syndrome. Lancet: 2015; 386 9997 995 1007
    • (2015) Lancet , vol.386 , Issue.9997 , pp. 995-1007
    • Zumla, A.1    Hui, D.S.2    Perlman, S.3
  • 33
    • 84883438898 scopus 로고    scopus 로고
    • Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: Evidence for proofreading and potential therapeutics
    • Smith E. C., Blanc H., Surdel M. C., Vignuzzi M., Denison M. R. Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics. PLoS Pathog: 2013; 9 8 e1003565
    • (2013) PLoS Pathog , vol.9 , Issue.8 , pp. e1003565
    • Smith, E.C.1    Blanc, H.2    Surdel, M.C.3    Vignuzzi, M.4    Denison, M.R.5
  • 34
    • 84874606884 scopus 로고    scopus 로고
    • Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential
    • Kindler E., Jónsdóttir H. R., Muth D., et al. Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential. MBio: 2013; 4 1 e00611 e00612
    • (2013) MBio , vol.4 , Issue.1 , pp. e00611-e00612
    • Kindler, E.1    Jónsdóttir, H.R.2    Muth, D.3
  • 35
    • 84876310574 scopus 로고    scopus 로고
    • Human cell tropism and innate immune system interactions of human respiratory coronavirus EMC compared to those of severe acute respiratory syndrome coronavirus
    • Zielecki F., Weber M., Eickmann M., et al. Human cell tropism and innate immune system interactions of human respiratory coronavirus EMC compared to those of severe acute respiratory syndrome coronavirus. J Virol: 2013; 87 9 5300 5304
    • (2013) J Virol , vol.87 , Issue.9 , pp. 5300-5304
    • Zielecki, F.1    Weber, M.2    Eickmann, M.3
  • 36
    • 84874996988 scopus 로고    scopus 로고
    • Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
    • Raj V. S., Mou H., Smits S. L., et al. Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature: 2013; 495 7440 251 254
    • (2013) Nature , vol.495 , Issue.7440 , pp. 251-254
    • Raj, V.S.1    Mou, H.2    Smits, S.L.3
  • 37
    • 0344395657 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
    • Li W., Moore M. J., Vasilieva N., et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature: 2003; 426 6965 450 454
    • (2003) Nature , vol.426 , Issue.6965 , pp. 450-454
    • Li, W.1    Moore, M.J.2    Vasilieva, N.3
  • 38
    • 84883443080 scopus 로고    scopus 로고
    • The Middle East respiratory syndrome- How worried should we be?
    • Perlman S. The Middle East respiratory syndrome--how worried should we be? MBio: 2013; 4 4 531 613
    • (2013) MBio , vol.4 , Issue.4 , pp. 531-613
    • Perlman, S.1
  • 39
    • 84886258554 scopus 로고    scopus 로고
    • Emerging human middle East respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungs
    • Hocke A. C., Becher A., Knepper J., et al. Emerging human middle East respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungs. Am J Respir Crit Care Med: 2013; 188 7 882 886
    • (2013) Am J Respir Crit Care Med , vol.188 , Issue.7 , pp. 882-886
    • Hocke, A.C.1    Becher, A.2    Knepper, J.3
  • 40
    • 84880177352 scopus 로고    scopus 로고
    • MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment
    • de Wilde A. H., Raj V. S., Oudshoorn D., et al. MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment. J Gen Virol: 2013; 94 Pt 8 1749 1760
    • (2013) J Gen Virol , vol.94 , pp. 1749-1760
    • De Wilde, A.H.1    Raj, V.S.2    Oudshoorn, D.3
  • 41
    • 0026729302 scopus 로고
    • Aminopeptidase N is a major receptor for the entero-pathogenic coronavirus TGEV
    • Delmas B., Gelfi J., L'Haridon R., et al. Aminopeptidase N is a major receptor for the entero-pathogenic coronavirus TGEV. Nature: 1992; 357 6377 417 420
    • (1992) Nature , vol.357 , Issue.6377 , pp. 417-420
    • Delmas, B.1    Gelfi, J.2    L'Haridon, R.3
  • 42
    • 84892463403 scopus 로고    scopus 로고
    • Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus
    • Raj V. S., Smits S. L., Provacia L. B., et al. Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus. J Virol: 2014; 88 3 1834 1838
    • (2014) J Virol , vol.88 , Issue.3 , pp. 1834-1838
    • Raj, V.S.1    Smits, S.L.2    Provacia, L.B.3
  • 43
    • 84875610424 scopus 로고    scopus 로고
    • A predicted receptor-binding and critical neutralizing domain in S protein of the novel human coronavirus HCoV-EMC
    • Jiang S., Lu L., Du L., Debnath A. K. A predicted receptor-binding and critical neutralizing domain in S protein of the novel human coronavirus HCoV-EMC. J Infect: 2013; 66 5 464 466
    • (2013) J Infect , vol.66 , Issue.5 , pp. 464-466
    • Jiang, S.1    Lu, L.2    Du, L.3    Debnath, A.K.4
  • 44
    • 77649222347 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 (ACE2) in disease pathogenesis
    • Imai Y., Kuba K., Ohto-Nakanishi T., Penninger J. M. Angiotensin-converting enzyme 2 (ACE2) in disease pathogenesis. Circ J: 2010; 74 3 405 410
    • (2010) Circ J , vol.74 , Issue.3 , pp. 405-410
    • Imai, Y.1    Kuba, K.2    Ohto-Nakanishi, T.3    Penninger, J.M.4
  • 45
    • 84879088543 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV is a human and murine neutrophil chemorepellent
    • Herlihy S. E., Pilling D., Maharjan A. S., Gomer R. H. Dipeptidyl peptidase IV is a human and murine neutrophil chemorepellent. J Immunol: 2013; 190 12 6468 6477
    • (2013) J Immunol , vol.190 , Issue.12 , pp. 6468-6477
    • Herlihy, S.E.1    Pilling, D.2    Maharjan, A.S.3    Gomer, R.H.4
  • 46
    • 84877339392 scopus 로고    scopus 로고
    • The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies
    • Gierer S., Bertram S., Kaup F., et al. The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies. J Virol: 2013; 87 10 5502 5511
    • (2013) J Virol , vol.87 , Issue.10 , pp. 5502-5511
    • Gierer, S.1    Bertram, S.2    Kaup, F.3
  • 47
    • 0037787851 scopus 로고    scopus 로고
    • Dipeptidyl-peptidase IV from bench to bedside: An update on structural properties, functions, and clinical aspects of the enzyme DPP IV
    • Lambeir A. M., Durinx C., Scharpé S., De Meester I. Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV. Crit Rev Clin Lab Sci: 2003; 40 3 209 294
    • (2003) Crit Rev Clin Lab Sci , vol.40 , Issue.3 , pp. 209-294
    • Lambeir, A.M.1    Durinx, C.2    Scharpé, S.3    De Meester, I.4
  • 48
    • 84934295654 scopus 로고    scopus 로고
    • Preliminary epidemiological assessment of MERS-CoV outbreak in South Korea, May to June 2015
    • Cowling B. J., Park M., Fang V. J., Wu P., Leung G. M., Wu J. T. Preliminary epidemiological assessment of MERS-CoV outbreak in South Korea, May to June 2015. Euro Surveill: 2015; 20 25 7 13
    • (2015) Euro Surveill , vol.20 , Issue.25 , pp. 7-13
    • Cowling, B.J.1    Park, M.2    Fang, V.J.3    Wu, P.4    Leung, G.M.5    Wu, J.T.6
  • 49
    • 84878523342 scopus 로고    scopus 로고
    • Tropism of and innate immune responses to the novel human betacoronavirus lineage C virus in human ex vivo respiratory organ cultures
    • Chan R. W., Chan M. C., Agnihothram S., et al. Tropism of and innate immune responses to the novel human betacoronavirus lineage C virus in human ex vivo respiratory organ cultures. J Virol: 2013; 87 12 6604 6614
    • (2013) J Virol , vol.87 , Issue.12 , pp. 6604-6614
    • Chan, R.W.1    Chan, M.C.2    Agnihothram, S.3
  • 50
    • 84898850857 scopus 로고    scopus 로고
    • Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: Implications for pathogenesis
    • Zhou J., Chu H., Li C., et al. Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis. J Infect Dis: 2014; 209 9 1331 1342
    • (2014) J Infect Dis , vol.209 , Issue.9 , pp. 1331-1342
    • Zhou, J.1    Chu, H.2    Li, C.3
  • 51
    • 84887016694 scopus 로고    scopus 로고
    • Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: Implications for pathogenesis and treatment
    • Lau S. K., Lau C. C., Chan K. H., et al. Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment. J Gen Virol: 2013; 94 Pt 12 2679 2690
    • (2013) J Gen Virol , vol.94 , pp. 2679-2690
    • Lau, S.K.1    Lau, C.C.2    Chan, K.H.3
  • 52
    • 34547814128 scopus 로고    scopus 로고
    • Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome
    • Canadian SARS Research Network
    • Cameron M. J., Ran L., Xu L., et al. Canadian SARS Research Network. Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome. J Virol: 2007; 81 16 8692 8706
    • (2007) J Virol , vol.81 , Issue.16 , pp. 8692-8706
    • Cameron, M.J.1    Ran, L.2    Xu, L.3
  • 53
    • 84901755321 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus: A case-control study of hospitalized patients
    • Al-Tawfiq J. A., Hinedi K., Ghandour J., et al. Middle East respiratory syndrome coronavirus: a case-control study of hospitalized patients. Clin Infect Dis: 2014; 59 2 160 165
    • (2014) Clin Infect Dis , vol.59 , Issue.2 , pp. 160-165
    • Al-Tawfiq, J.A.1    Hinedi, K.2    Ghandour, J.3
  • 54
    • 84926184419 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus disease in children
    • Memish Z. A., Al-Tawfiq J. A., Assiri A., et al. Middle East respiratory syndrome coronavirus disease in children. Pediatr Infect Dis J: 2014; 33 9 904 906
    • (2014) Pediatr Infect Dis J , vol.33 , Issue.9 , pp. 904-906
    • Memish, Z.A.1    Al-Tawfiq, J.A.2    Assiri, A.3
  • 55
    • 84880053841 scopus 로고    scopus 로고
    • Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: A report of nosocomial transmission
    • MERS-CoV Study Group
    • Guery B., Poissy J., el Mansouf L., et al. MERS-CoV Study Group. Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission. Lancet: 2013; 381 9885 2265 2272
    • (2013) Lancet , vol.381 , Issue.9885 , pp. 2265-2272
    • Guery, B.1    Poissy, J.2    El Mansouf, L.3
  • 56
    • 84882614929 scopus 로고    scopus 로고
    • Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection
    • Drosten C., Seilmaier M., Corman V. M., et al. Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection. Lancet Infect Dis: 2013; 13 9 745 751
    • (2013) Lancet Infect Dis , vol.13 , Issue.9 , pp. 745-751
    • Drosten, C.1    Seilmaier, M.2    Corman, V.M.3
  • 57
    • 84901435018 scopus 로고    scopus 로고
    • Prevalence of MERS-CoV nasal carriage and compliance with the Saudi health recommendations among pilgrims attending the 2013 Hajj
    • Memish Z. A., Assiri A., Almasri M., et al. Prevalence of MERS-CoV nasal carriage and compliance with the Saudi health recommendations among pilgrims attending the 2013 Hajj. J Infect Dis: 2014; 210 7 1067 1072
    • (2014) J Infect Dis , vol.210 , Issue.7 , pp. 1067-1072
    • Memish, Z.A.1    Assiri, A.2    Almasri, M.3
  • 58
    • 84906939065 scopus 로고    scopus 로고
    • Hospital-associated outbreak of Middle East respiratory syndrome coronavirus: A serologic, epidemiologic, and clinical description
    • Jordan MERS-CoV Investigation Team
    • Al-Abdallat M. M., Payne D. C., Alqasrawi S., et al. Jordan MERS-CoV Investigation Team. Hospital-associated outbreak of Middle East respiratory syndrome coronavirus: a serologic, epidemiologic, and clinical description. Clin Infect Dis: 2014; 59 9 1225 1233
    • (2014) Clin Infect Dis , vol.59 , Issue.9 , pp. 1225-1233
    • Al-Abdallat, M.M.1    Payne, D.C.2    Alqasrawi, S.3
  • 59
    • 84910134528 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus (MERS-CoV) infection: Chest CT findings
    • Ajlan A. M., Ahyad R. A., Jamjoom L. G., Alharthy A., Madani T. A. Middle East respiratory syndrome coronavirus (MERS-CoV) infection: chest CT findings. AJR Am J Roentgenol: 2014; 203 4 782 787
    • (2014) AJR Am J Roentgenol , vol.203 , Issue.4 , pp. 782-787
    • Ajlan, A.M.1    Ahyad, R.A.2    Jamjoom, L.G.3    Alharthy, A.4    Madani, T.A.5
  • 60
    • 0038024612 scopus 로고    scopus 로고
    • Lung pathology of fatal severe acute respiratory syndrome
    • Nicholls J. M., Poon L. L., Lee K. C., et al. Lung pathology of fatal severe acute respiratory syndrome. Lancet: 2003; 361 9371 1773 1778
    • (2003) Lancet , vol.361 , Issue.9371 , pp. 1773-1778
    • Nicholls, J.M.1    Poon, L.L.2    Lee, K.C.3
  • 61
    • 12144288187 scopus 로고    scopus 로고
    • Pulmonary pathological features in coronavirus associated severe acute respiratory syndrome (SARS)
    • Tse G. M., To K. F., Chan P. K., et al. Pulmonary pathological features in coronavirus associated severe acute respiratory syndrome (SARS). J Clin Pathol: 2004; 57 3 260 265
    • (2004) J Clin Pathol , vol.57 , Issue.3 , pp. 260-265
    • Tse, G.M.1    To, K.F.2    Chan, P.K.3
  • 62
    • 84879571351 scopus 로고    scopus 로고
    • Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus
    • Josset L., Menachery V. D., Gralinski L. E., et al. Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus. MBio: 2013; 4 3 e00165 e13
    • (2013) MBio , vol.4 , Issue.3 , pp. e00165-e001613
    • Josset, L.1    Menachery, V.D.2    Gralinski, L.E.3
  • 63
    • 84895823870 scopus 로고    scopus 로고
    • Distinct immune response in two MERS-CoV-infected patients: Can we go from bench to bedside?
    • Faure E., Poissy J., Goffard A., et al. Distinct immune response in two MERS-CoV-infected patients: can we go from bench to bedside? PLoS ONE: 2014; 9 2 e88716
    • (2014) PLoS ONE , vol.9 , Issue.2 , pp. e88716
    • Faure, E.1    Poissy, J.2    Goffard, A.3
  • 64
    • 84920655857 scopus 로고    scopus 로고
    • Serological assays for emerging coronaviruses: Challenges and pitfalls
    • Meyer B., Drosten C., Müller M. A. Serological assays for emerging coronaviruses: challenges and pitfalls. Virus Res: 2014; 194 175 183
    • (2014) Virus Res , vol.194 , pp. 175-183
    • Meyer, B.1    Drosten, C.2    Müller, M.A.3
  • 65
    • 84911945010 scopus 로고    scopus 로고
    • Virological and serological analysis of a recent Middle East respiratory syndrome coronavirus infection case on a triple combination antiviral regimen
    • Spanakis N., Tsiodras S., Haagmans B. L., et al. Virological and serological analysis of a recent Middle East respiratory syndrome coronavirus infection case on a triple combination antiviral regimen. Int J Antimicrob Agents: 2014; 44 6 528 532
    • (2014) Int J Antimicrob Agents , vol.44 , Issue.6 , pp. 528-532
    • Spanakis, N.1    Tsiodras, S.2    Haagmans, B.L.3
  • 66
    • 84953838128 scopus 로고    scopus 로고
    • Human-dromedary camel interactions and the risk of acquiring zoonotic Middle East respiratory syndrome coronavirus infection
    • Gossner C., Danielson N., Gervelmeyer A., et al. Human-dromedary camel interactions and the risk of acquiring zoonotic Middle East respiratory syndrome coronavirus infection. Zoonoses Public Health: 2016; 63 1 1 9
    • (2016) Zoonoses Public Health , vol.63 , Issue.1 , pp. 1-9
    • Gossner, C.1    Danielson, N.2    Gervelmeyer, A.3
  • 67
    • 84906559641 scopus 로고    scopus 로고
    • Detection of Middle East respiratory syndrome coronavirus using reverse transcription loop-mediated isothermal amplification (RT-LAMP)
    • Shirato K., Yano T., Senba S., et al. Detection of Middle East respiratory syndrome coronavirus using reverse transcription loop-mediated isothermal amplification (RT-LAMP). Virol J: 2014; 11 139
    • (2014) Virol J , vol.11 , pp. 139
    • Shirato, K.1    Yano, T.2    Senba, S.3
  • 68
    • 84883286587 scopus 로고    scopus 로고
    • Identification of a receptor-binding domain in the S protein of the novel human coronavirus Middle East respiratory syndrome coronavirus as an essential target for vaccine development
    • Du L., Zhao G., Kou Z., et al. Identification of a receptor-binding domain in the S protein of the novel human coronavirus Middle East respiratory syndrome coronavirus as an essential target for vaccine development. J Virol: 2013; 87 17 9939 9942
    • (2013) J Virol , vol.87 , Issue.17 , pp. 9939-9942
    • Du, L.1    Zhao, G.2    Kou, Z.3
  • 69
    • 84924023314 scopus 로고    scopus 로고
    • Identification of protein receptors for coronaviruses by mass spectrometry
    • Raj V. S., Lamers M. M., Smits S. L., et al. Identification of protein receptors for coronaviruses by mass spectrometry. Methods Mol Biol: 2015; 1282 165 182
    • (2015) Methods Mol Biol , vol.1282 , pp. 165-182
    • Raj, V.S.1    Lamers, M.M.2    Smits, S.L.3
  • 70
    • 84901422841 scopus 로고    scopus 로고
    • Respiratory tract samples, viral load, and genome fraction yield in patients with Middle East respiratory syndrome
    • Memish Z. A., Al-Tawfiq J. A., Makhdoom H. Q., et al. Respiratory tract samples, viral load, and genome fraction yield in patients with Middle East respiratory syndrome. J Infect Dis: 2014; 210 10 1590 1594
    • (2014) J Infect Dis , vol.210 , Issue.10 , pp. 1590-1594
    • Memish, Z.A.1    Al-Tawfiq, J.A.2    Makhdoom, H.Q.3
  • 71
    • 84945570358 scopus 로고    scopus 로고
    • Antiviral treatment guidelines for Middle East respiratory syndrome
    • Rapid Response Team
    • Chong Y. P., Song J. Y., Seo Y. B., Choi J. P., Shin H. S.; Rapid Response Team. Antiviral treatment guidelines for Middle East respiratory syndrome. Infect Chemother: 2015; 47 3 212 222
    • (2015) Infect Chemother , vol.47 , Issue.3 , pp. 212-222
    • Chong, Y.P.1    Song, J.Y.2    Seo, Y.B.3    Choi, J.P.4    Shin, H.S.5
  • 72
    • 84955391557 scopus 로고    scopus 로고
    • Treatment with lopinavir/ritonavir or interferon-β1b improves outcome of MERS-CoV infection in a nonhuman primate model of common marmoset
    • Chan J. F., Yao Y., Yeung M. L., et al. Treatment with lopinavir/ritonavir or interferon-β1b improves outcome of MERS-CoV infection in a nonhuman primate model of common marmoset. J Infect Dis: 2015; 212 12 1904 1913
    • (2015) J Infect Dis , vol.212 , Issue.12 , pp. 1904-1913
    • Chan, J.F.1    Yao, Y.2    Yeung, M.3
  • 73
    • 84877248581 scopus 로고    scopus 로고
    • What the infectious disease physician needs to know about pegylated interferon and ribavirin
    • Gara N., Ghany M. G. What the infectious disease physician needs to know about pegylated interferon and ribavirin. Clin Infect Dis: 2013; 56 11 1629 1636
    • (2013) Clin Infect Dis , vol.56 , Issue.11 , pp. 1629-1636
    • Gara, N.1    Ghany, M.G.2
  • 74
    • 84922440585 scopus 로고    scopus 로고
    • The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: A systematic review and exploratory meta-analysis
    • Convalescent Plasma Study Group
    • Mair-Jenkins J., Saavedra-Campos M., Baillie J. K., et al. Convalescent Plasma Study Group. The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: a systematic review and exploratory meta-analysis. J Infect Dis: 2015; 211 1 80 90
    • (2015) J Infect Dis , vol.211 , Issue.1 , pp. 80-90
    • Mair-Jenkins, J.1    Saavedra-Campos, M.2    Baillie, J.K.3
  • 75
    • 84897578593 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome vs. The Middle East respiratory syndrome
    • Hui D. S., Memish Z. A., Zumla A. Severe acute respiratory syndrome vs. the Middle East respiratory syndrome. Curr Opin Pulm Med: 2014; 20 3 233 241
    • (2014) Curr Opin Pulm Med , vol.20 , Issue.3 , pp. 233-241
    • Hui, D.S.1    Memish, Z.A.2    Zumla, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.