-
1
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp, R. et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 352, 987-996 (2005).
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 987-996
-
-
Stupp, R.1
-
2
-
-
43249095919
-
Tumor angiogenesis
-
Kerbel, R. S. Tumor angiogenesis. N. Engl. J. Med. 358, 2039-2049 (2008).
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 2039-2049
-
-
Kerbel, R.S.1
-
3
-
-
70449517400
-
Antiangiogenic therapies for high-grade glioma
-
Norden, A. D., Drappatz, J. & Wen, P. Y. Antiangiogenic therapies for high-grade glioma. Nat. Rev. Neurol. 5, 610-620 (2009).
-
(2009)
Nat. Rev. Neurol.
, vol.5
, pp. 610-620
-
-
Norden, A.D.1
Drappatz, J.2
Wen, P.Y.3
-
4
-
-
47949099628
-
Modes of resistance to anti-angiogenic therapy
-
Bergers, G. & Hanahan, D. Modes of resistance to anti-angiogenic therapy. Nat. Rev. Cancer 8, 592-603 (2008).
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
5
-
-
84894194756
-
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma
-
Chinot, O. L. et al. Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma. N. Engl. J. Med. 370, 709-722 (2014).
-
(2014)
N. Engl. J. Med.
, vol.370
, pp. 709-722
-
-
Chinot, O.L.1
-
6
-
-
84894114159
-
A randomized trial of bevacizumab for newly diagnosed glioblastoma
-
Gilbert, M. R. et al. A randomized trial of bevacizumab for newly diagnosed glioblastoma. N. Engl. J. Med. 370, 699-708 (2014).
-
(2014)
N. Engl. J. Med.
, vol.370
, pp. 699-708
-
-
Gilbert, M.R.1
-
7
-
-
60649116273
-
Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: Impact on local control and patient survival
-
Narayana, A. et al. Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: impact on local control and patient survival. J. Neurosurg. 110, 173-180 (2009).
-
(2009)
J. Neurosurg.
, vol.110
, pp. 173-180
-
-
Narayana, A.1
-
8
-
-
41649112610
-
Bevacizumab for recurrent malignant gliomas: Efficacy, toxicity, and patterns of recurrence
-
Norden, A. D. et al. Bevacizumab for recurrent malignant gliomas: efficacy, toxicity, and patterns of recurrence. Neurology 70, 779-787 (2008).
-
(2008)
Neurology
, vol.70
, pp. 779-787
-
-
Norden, A.D.1
-
9
-
-
84861145421
-
Microarray analysis verifies two distinct phenotypes of glioblastomas resistant to antiangiogenic therapy
-
DeLay, M. et al. Microarray analysis verifies two distinct phenotypes of glioblastomas resistant to antiangiogenic therapy. Clin. Cancer Res. 18, 2930-2942 (2012).
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 2930-2942
-
-
DeLay, M.1
-
10
-
-
60649087564
-
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
-
Ebos, J. M. et al. Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 15, 232-239 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 232-239
-
-
Ebos, J.M.1
-
11
-
-
79952740612
-
Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma
-
Keunen, O. et al. Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proc. Natl Acad. Sci. USA 108, 3749-3754 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 3749-3754
-
-
Keunen, O.1
-
12
-
-
84863754907
-
VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex
-
Lu, K. V. et al. VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex. Cancer Cell 22, 21-35 (2012).
-
(2012)
Cancer Cell
, vol.22
, pp. 21-35
-
-
Lu, K.V.1
-
13
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Paez-Ribes, M. et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 15, 220-231 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 220-231
-
-
Paez-Ribes, M.1
-
14
-
-
84866693927
-
Controlling escape from angiogenesis inhibitors
-
Sennino, B. & McDonald, D. M. Controlling escape from angiogenesis inhibitors. Nat. Rev. Cancer 12, 699-709 (2012).
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 699-709
-
-
Sennino, B.1
McDonald, D.M.2
-
15
-
-
84905731719
-
Blocking lipid synthesis overcomes tumor regrowth and metastasis after antiangiogenic therapy withdrawal
-
Sounni, N. E. et al. Blocking lipid synthesis overcomes tumor regrowth and metastasis after antiangiogenic therapy withdrawal. Cell Metab. 20, 280-294 (2014).
-
(2014)
Cell Metab.
, vol.20
, pp. 280-294
-
-
Sounni, N.E.1
-
16
-
-
80052712201
-
The ins and outs of the epithelial to mesenchymal transition in health and disease
-
Nieto, M. A. The ins and outs of the epithelial to mesenchymal transition in health and disease. Annu. Rev. Cell Dev. Biol. 27, 347-376 (2011).
-
(2011)
Annu. Rev. Cell Dev. Biol.
, vol.27
, pp. 347-376
-
-
Nieto, M.A.1
-
17
-
-
84897019542
-
Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology
-
Semenza, G. L. Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology. Annu. Rev. Pathol. 9, 47-71 (2014).
-
(2014)
Annu. Rev. Pathol.
, vol.9
, pp. 47-71
-
-
Semenza, G.L.1
-
18
-
-
77649114060
-
Eph receptors and ephrins in cancer: Bidirectional signalling and beyond
-
Pasquale, E. B. Eph receptors and ephrins in cancer: bidirectional signalling and beyond. Nat. Rev. Cancer 10, 165-180 (2010).
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 165-180
-
-
Pasquale, E.B.1
-
19
-
-
34247615569
-
Bidirectional Eph-ephrin signaling during axon guidance
-
Egea, J. & Klein, R. Bidirectional Eph-ephrin signaling during axon guidance. Trends. Cell Biol. 17, 230-238 (2007).
-
(2007)
Trends. Cell Biol.
, vol.17
, pp. 230-238
-
-
Egea, J.1
Klein, R.2
-
20
-
-
84867882834
-
Eph/ephrin signalling during development
-
Klein, R. Eph/ephrin signalling during development. Development 139, 4105-4109 (2012).
-
(2012)
Development
, vol.139
, pp. 4105-4109
-
-
Klein, R.1
-
21
-
-
21344460054
-
EphB receptor activity suppresses colorectal cancer progression
-
Batlle, E. et al. EphB receptor activity suppresses colorectal cancer progression. Nature 435, 1126-1130 (2005).
-
(2005)
Nature
, vol.435
, pp. 1126-1130
-
-
Batlle, E.1
-
22
-
-
78650749129
-
Molecular signatures classify astrocytic gliomas by IDH1 mutation status
-
Toedt, G. et al. Molecular signatures classify astrocytic gliomas by IDH1 mutation status. Int. J. Cancer 128, 1095-1103 (2011).
-
(2011)
Int. J. Cancer
, vol.128
, pp. 1095-1103
-
-
Toedt, G.1
-
23
-
-
0346732915
-
Hippocampal plasticity requires postsynaptic ephrinBs
-
Grunwald, I. C. et al. Hippocampal plasticity requires postsynaptic ephrinBs. Nat. Neurosci. 7, 33-40 (2004).
-
(2004)
Nat. Neurosci.
, vol.7
, pp. 33-40
-
-
Grunwald, I.C.1
-
24
-
-
0041382820
-
The hypoxic response of tumors is dependent on their microenvironment
-
Blouw, B. et al. The hypoxic response of tumors is dependent on their microenvironment. Cancer Cell 4, 133-146 (2003).
-
(2003)
Cancer Cell
, vol.4
, pp. 133-146
-
-
Blouw, B.1
-
25
-
-
84923360067
-
Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR
-
Henze, A. T. et al. Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR. Nat. Commun. 5, 5582 (2014).
-
(2014)
Nat. Commun.
, vol.5
, pp. 5582
-
-
Henze, A.T.1
-
26
-
-
77953022206
-
Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis
-
Sawamiphak, S. et al. Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis. Nature 465, 487-491 (2010).
-
(2010)
Nature
, vol.465
, pp. 487-491
-
-
Sawamiphak, S.1
-
27
-
-
35548976379
-
EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells
-
Cortina, C. et al. EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells. Nat. Genet. 39, 1376-1383 (2007).
-
(2007)
Nat. Genet.
, vol.39
, pp. 1376-1383
-
-
Cortina, C.1
-
28
-
-
84655161946
-
HIF1alpha and HIF2alpha: Sibling rivalry in hypoxic tumour growth and progression
-
Keith, B., Johnson, R. S. & Simon, M. C. HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression. Nat. Rev. Cancer 12, 9-22 (2011).
-
(2011)
Nat. Rev. Cancer
, vol.12
, pp. 9-22
-
-
Keith, B.1
Johnson, R.S.2
Simon, M.C.3
-
29
-
-
44449144396
-
Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
-
Yang, J. & Weinberg, R. A. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev. Cell 14, 818-829 (2008).
-
(2008)
Dev. Cell
, vol.14
, pp. 818-829
-
-
Yang, J.1
Weinberg, R.A.2
-
30
-
-
33845724527
-
VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail
-
Evans, A. J. et al. VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail. Mol. Cell. Biol. 27, 157-169 (2007).
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 157-169
-
-
Evans, A.J.1
-
31
-
-
33645090169
-
Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3 ZFHX1A and ZFHX1B
-
Krishnamachary, B. et al. Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B. Cancer Res. 66, 2725-2731 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 2725-2731
-
-
Krishnamachary, B.1
-
32
-
-
40249113328
-
Direct regulation of TWIST by HIF-1alpha promotes metastasis
-
Yang, M. H. et al. Direct regulation of TWIST by HIF-1alpha promotes metastasis. Nat. Cell Biol. 10, 295-305 (2008).
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 295-305
-
-
Yang, M.H.1
-
33
-
-
34547610957
-
UPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells
-
Lester, R. D., Jo, M., Montel, V., Takimoto, S. & Gonias, S. L. uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells. J. Cell Biol. 178, 425-436 (2007).
-
(2007)
J. Cell Biol.
, vol.178
, pp. 425-436
-
-
Lester, R.D.1
Jo, M.2
Montel, V.3
Takimoto, S.4
Gonias, S.L.5
-
34
-
-
34249289041
-
Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
-
Peinado, H., Olmeda, D. & Cano, A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat. Rev. Cancer 7, 415-428 (2007).
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 415-428
-
-
Peinado, H.1
Olmeda, D.2
Snail, C.A.3
-
35
-
-
84873050284
-
Regulatory networks defining EMT during cancer initiation and progression
-
De Craene, B. & Berx, G. Regulatory networks defining EMT during cancer initiation and progression. Nat. Rev. Cancer 13, 97-110 (2013).
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 97-110
-
-
De Craene, B.1
Berx, G.2
-
36
-
-
0035884609
-
Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2
-
Kunkel, P. et al. Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2. Cancer Res. 61, 6624-6628 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 6624-6628
-
-
Kunkel, P.1
-
37
-
-
41149084179
-
Eph-ephrin bidirectional signaling in physiology and disease
-
Pasquale, E. B. Eph-ephrin bidirectional signaling in physiology and disease. Cell 133, 38-52 (2008).
-
(2008)
Cell
, vol.133
, pp. 38-52
-
-
Pasquale, E.B.1
-
38
-
-
33344471782
-
Eph receptor and ephrin ligandmediated interactions during angiogenesis and tumor progression
-
Heroult, M., Schaffner, F. & Augustin, H. G. Eph receptor and ephrin ligandmediated interactions during angiogenesis and tumor progression. Exp. Cell Res. 312, 642-650 (2006).
-
(2006)
Exp. Cell Res.
, vol.312
, pp. 642-650
-
-
Heroult, M.1
Schaffner, F.2
Augustin, H.G.3
-
39
-
-
33748997415
-
Ephrin-B3 ligand promotes glioma invasion through activation of Rac1
-
Nakada, M., Drake, K. L., Nakada, S., Niska, J. A. & Berens, M. E. Ephrin-B3 ligand promotes glioma invasion through activation of Rac1. Cancer Res. 66, 8492-8500 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 8492-8500
-
-
Nakada, M.1
Drake, K.L.2
Nakada, S.3
Niska, J.A.4
Berens, M.E.5
-
40
-
-
0034213146
-
Expression of hypoxia-inducible factor 1alpha in brain tumors: Association with angiogenesis, invasion, and progression
-
Zagzag, D. et al. Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression. Cancer 88, 2606-2618 (2000).
-
(2000)
Cancer
, vol.88
, pp. 2606-2618
-
-
Zagzag, D.1
-
41
-
-
32544436614
-
EphB4 controls blood vascular morphogenesis during postnatal angiogenesis
-
Erber, R. et al. EphB4 controls blood vascular morphogenesis during postnatal angiogenesis. EMBO J. 25, 628-641 (2006).
-
(2006)
EMBO J.
, vol.25
, pp. 628-641
-
-
Erber, R.1
-
42
-
-
84860729590
-
Expression of EphrinB2 and EphB4 in glioma tissues correlated to the progression of glioma and the prognosis of glioblastoma patients
-
Tu, Y. et al. Expression of EphrinB2 and EphB4 in glioma tissues correlated to the progression of glioma and the prognosis of glioblastoma patients. Clin. Transl. Oncol. 14, 214-220 (2012).
-
(2012)
Clin. Transl. Oncol.
, vol.14
, pp. 214-220
-
-
Tu, Y.1
-
43
-
-
81855169565
-
Cancer invasion and the microenvironment: Plasticity and reciprocity
-
Friedl, P. & Alexander, S. Cancer invasion and the microenvironment: plasticity and reciprocity. Cell 147, 992-1009 (2011).
-
(2011)
Cell
, vol.147
, pp. 992-1009
-
-
Friedl, P.1
Alexander, S.2
-
44
-
-
84922222306
-
Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1alpha-ZEB1 axis
-
Joseph, J. V. et al. Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1alpha-ZEB1 axis. Cancer Lett. 359, 107-116 (2015).
-
(2015)
Cancer Lett.
, vol.359
, pp. 107-116
-
-
Joseph, J.V.1
-
45
-
-
84928726641
-
MIR-203 downregulation is responsible for chemoresistance in human glioblastoma by promoting epithelial-mesenchymal transition via SNAI2
-
Liao, H. et al. MiR-203 downregulation is responsible for chemoresistance in human glioblastoma by promoting epithelial-mesenchymal transition via SNAI2. Oncotarget 6, 8914-8928 (2015).
-
(2015)
Oncotarget
, vol.6
, pp. 8914-8928
-
-
Liao, H.1
-
46
-
-
84899426379
-
Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant glioma
-
Mahabir, R. et al. Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant glioma. Neuro. Oncol. 16, 671-685 (2014).
-
(2014)
Neuro. Oncol.
, vol.16
, pp. 671-685
-
-
Mahabir, R.1
-
47
-
-
84902440194
-
Snail plays an oncogenic role in glioblastoma by promoting epithelial mesenchymal transition
-
Myung, J. K., Choi, S. A., Kim, S. K., Wang, K. C. & Park, S. H. Snail plays an oncogenic role in glioblastoma by promoting epithelial mesenchymal transition. Int. J. Clin. Exp. Pathol. 7, 1977-1987 (2014).
-
(2014)
Int. J. Clin. Exp. Pathol.
, vol.7
, pp. 1977-1987
-
-
Myung, J.K.1
Choi, S.A.2
Kim, S.K.3
Wang, K.C.4
Park, S.H.5
-
48
-
-
84881540768
-
The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance
-
Siebzehnrubl, F. A. et al. The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance. EMBO Mol. Med. 5, 1196-1212 (2013).
-
(2013)
EMBO Mol. Med.
, vol.5
, pp. 1196-1212
-
-
Siebzehnrubl, F.A.1
-
49
-
-
84937057520
-
CXCL12/CXCR4 axis upregulates twist to induce EMT in human glioblastoma
-
Yao, C. et al. CXCL12/CXCR4 axis upregulates twist to induce EMT in human glioblastoma. Mol. Neurobiol. 53, 3948-3953 (2016).
-
(2016)
Mol. Neurobiol.
, vol.53
, pp. 3948-3953
-
-
Yao, C.1
-
50
-
-
84962079674
-
SHP-2-upregulated ZEB1 is important for PDGFRalpha-driven glioma epithelial-mesenchymal transition and invasion in mice and humans
-
Zhang, L. et al. SHP-2-upregulated ZEB1 is important for PDGFRalpha-driven glioma epithelial-mesenchymal transition and invasion in mice and humans. Oncogene. doi: 10.1038/onc.2016.100 (2016).
-
(2016)
Oncogene.
-
-
Zhang, L.1
-
51
-
-
84946221385
-
ZEB1 Promotes Invasion in Human Fetal Neural Stem Cells and Hypoxic Glioma Neurospheres
-
Kahlert, U. D. et al. ZEB1 Promotes Invasion in Human Fetal Neural Stem Cells and Hypoxic Glioma Neurospheres. Brain. Pathol. 25, 724-732 (2015).
-
(2015)
Brain. Pathol.
, vol.25
, pp. 724-732
-
-
Kahlert, U.D.1
-
52
-
-
84956959861
-
MicroRNA-200b inhibits the growth and metastasis of glioma cells via targeting ZEB2
-
Li, J. et al. MicroRNA-200b inhibits the growth and metastasis of glioma cells via targeting ZEB2. Int. J. Oncol. 48, 541-550 (2016).
-
(2016)
Int. J. Oncol.
, vol.48
, pp. 541-550
-
-
Li, J.1
-
53
-
-
84949623268
-
MIR-590-3p suppresses cancer cell migration, invasion and epithelial-mesenchymal transition in glioblastoma multiforme by targeting ZEB1 and ZEB2
-
Pang, H., Zheng, Y., Zhao, Y., Xiu, X. &Wang, J. miR-590-3p suppresses cancer cell migration, invasion and epithelial-mesenchymal transition in glioblastoma multiforme by targeting ZEB1 and ZEB2. Biochem. Biophys. Res. Commun. 468, 739-745 (2015).
-
(2015)
Biochem. Biophys. Res. Commun.
, vol.468
, pp. 739-745
-
-
Pang, H.1
Zheng, Y.2
Zhao, Y.3
Xiu, X.4
Wang, J.5
-
54
-
-
0037478437
-
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
-
Pennacchietti, S. et al. Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. Cancer Cell 3, 347-361 (2003).
-
(2003)
Cancer Cell
, vol.3
, pp. 347-361
-
-
Pennacchietti, S.1
-
55
-
-
84899732336
-
And the tumor microenvironment: Vascular endothelial growth factor and beyond
-
Mittal, K., Ebos, J. & Rini, B. Angiogenesis and the tumor microenvironment: vascular endothelial growth factor and beyond. Semin. Oncol. 41, 235-251 (2014).
-
(2014)
Semin. Oncol.
, vol.41
, pp. 235-251
-
-
Mittal, K.1
Ebos, J.2
Angiogenesis, R.B.3
-
56
-
-
84891890658
-
Bevacizumab and micrometastases: Revisiting the preclinical and clinical rollercoaster
-
Mountzios, G., Pentheroudakis, G. & Carmeliet, P. Bevacizumab and micrometastases: revisiting the preclinical and clinical rollercoaster. Pharmacol. Ther. 141, 117-124 (2014).
-
(2014)
Pharmacol. Ther.
, vol.141
, pp. 117-124
-
-
Mountzios, G.1
Pentheroudakis, G.2
Carmeliet, P.3
-
57
-
-
84908012698
-
Fatty acid uptake and lipid storage induced by HIF-1alpha contribute to cell growth and survival after hypoxia-reoxygenation
-
Bensaad, K. et al. Fatty acid uptake and lipid storage induced by HIF-1alpha contribute to cell growth and survival after hypoxia-reoxygenation. Cell Rep. 9, 349-365 (2014).
-
(2014)
Cell Rep.
, vol.9
, pp. 349-365
-
-
Bensaad, K.1
-
58
-
-
84856302564
-
Bevacizumab impairs oxidative energy metabolism and shows antitumoral effects in recurrent glioblastomas: A 31P/1H MRSI and quantitative magnetic resonance imaging study
-
Hattingen, E. et al. Bevacizumab impairs oxidative energy metabolism and shows antitumoral effects in recurrent glioblastomas: a 31P/1H MRSI and quantitative magnetic resonance imaging study. Neuro. Oncol. 13, 1349-1363 (2011).
-
(2011)
Neuro. Oncol.
, vol.13
, pp. 1349-1363
-
-
Hattingen, E.1
-
59
-
-
84877098516
-
Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance
-
Jahangiri, A. et al. Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance. Clin. Cancer. Res. 19, 1773-1783 (2013).
-
(2013)
Clin. Cancer. Res.
, vol.19
, pp. 1773-1783
-
-
Jahangiri, A.1
-
60
-
-
84878620894
-
Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts
-
Kumar, K. et al. Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts. J. Mol. Med. (Berl) 91, 749-758 (2013).
-
(2013)
J. Mol. Med. (Berl)
, vol.91
, pp. 749-758
-
-
Kumar, K.1
-
61
-
-
84855167770
-
Assessing early therapeutic response to bevacizumab in primary breast cancer using magnetic resonance imaging and gene expression profiles
-
Mehta, S. et al. Assessing early therapeutic response to bevacizumab in primary breast cancer using magnetic resonance imaging and gene expression profiles. J. Natl Cancer Inst. Monogr. 2011, 71-74 (2011).
-
(2011)
J. Natl Cancer Inst. Monogr.
, vol.2011
, pp. 71-74
-
-
Mehta, S.1
-
62
-
-
80051544936
-
Antiangiogenic therapy for primary liver cancer: Correlation of changes in dynamic contrast-enhanced magnetic resonance imaging with tissue hypoxia markers and clinical response
-
Yopp, A. C. et al. Antiangiogenic therapy for primary liver cancer: correlation of changes in dynamic contrast-enhanced magnetic resonance imaging with tissue hypoxia markers and clinical response. Ann. Surg. Oncol. 18, 2192-2199 (2011).
-
(2011)
Ann. Surg. Oncol.
, vol.18
, pp. 2192-2199
-
-
Yopp, A.C.1
-
63
-
-
84926166792
-
Metabolic and hypoxic adaptation to anti-angiogenic therapy: A target for induced essentiality
-
McIntyre, A. & Harris, A. L. Metabolic and hypoxic adaptation to anti-angiogenic therapy: a target for induced essentiality. EMBO Mol. Med. 7, 368-379 (2015).
-
(2015)
EMBO Mol. Med.
, vol.7
, pp. 368-379
-
-
McIntyre, A.1
Harris, A.L.2
-
64
-
-
50249188450
-
Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors
-
Essmann, C. L. et al. Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors. Nat. Neurosci. 11, 1035-1043 (2008).
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 1035-1043
-
-
Essmann, C.L.1
-
65
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
Louis, D. N. et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 114, 97-109 (2007).
-
(2007)
Acta Neuropathol.
, vol.114
, pp. 97-109
-
-
Louis, D.N.1
-
66
-
-
84875740314
-
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
-
Gao, J. et al. Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci. Signal. 6, pl1 (2013).
-
(2013)
Sci. Signal.
, vol.6
, pp. l1
-
-
Gao, J.1
-
67
-
-
0042425741
-
Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction
-
van den Boom, J. et al. Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction. Am. J. Pathol. 163, 1033-1043 (2003).
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 1033-1043
-
-
Van Den Boom, J.1
-
68
-
-
0035924587
-
Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity
-
Grunwald, I. C. et al. Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity. Neuron 32, 1027-1040 (2001).
-
(2001)
Neuron
, vol.32
, pp. 1027-1040
-
-
Grunwald, I.C.1
-
69
-
-
0036241054
-
EphrinB phosphorylation and reverse signaling: Regulation by Src kinases and PTP-BL phosphatase
-
Palmer, A. et al. EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase. Mol. Cell 9, 725-737 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 725-737
-
-
Palmer, A.1
-
70
-
-
21644481842
-
Tumor cell invasion assays
-
Shaw, L. M. Tumor cell invasion assays. Methods Mol. Biol. 294, 97-105 (2005).
-
(2005)
Methods Mol. Biol.
, vol.294
, pp. 97-105
-
-
Shaw, L.M.1
|