-
1
-
-
84858016877
-
Induction of ZEB proteins by inactivation of RB protein is key determinant of mesenchymal phenotype of breast cancer
-
Arima Y, Hayashi H, Sasaki M, Hosonaga M, Goto TM, Chiyoda T, et al (2012) Induction of ZEB proteins by inactivation of RB protein is key determinant of mesenchymal phenotype of breast cancer. J Biol Chem 287: 7896-7906.
-
(2012)
J Biol Chem
, vol.287
, pp. 7896-7906
-
-
Arima, Y.1
Hayashi, H.2
Sasaki, M.3
Hosonaga, M.4
Goto, T.M.5
Chiyoda, T.6
-
2
-
-
79251591038
-
Glioblastoma, cancer stem cells and hypoxia
-
Bar EE, (2011) Glioblastoma, cancer stem cells and hypoxia. Brain Pathol 21: 119-129.
-
(2011)
Brain Pathol
, vol.21
, pp. 119-129
-
-
Bar, E.E.1
-
3
-
-
77956503727
-
Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres
-
Bar EE, Lin A, Mahairaki V, Matsui W, Eberhart CG, (2010) Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres. Am J Pathol 177: 1491-1502.
-
(2010)
Am J Pathol
, vol.177
, pp. 1491-1502
-
-
Bar, E.E.1
Lin, A.2
Mahairaki, V.3
Matsui, W.4
Eberhart, C.G.5
-
4
-
-
84861527239
-
To differentiate or not - Routes towards metastasis
-
Brabletz T, (2012) To differentiate or not-routes towards metastasis. Nat Rev Cancer 12: 425-436.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 425-436
-
-
Brabletz, T.1
-
5
-
-
25444495269
-
Opinion: Migrating cancer stem cells - An integrated concept of malignant tumour progression
-
Brabletz T, Jung A, Spaderna S, Hlubek F, Kirchner T, (2005) Opinion: migrating cancer stem cells-an integrated concept of malignant tumour progression. Nat Rev Cancer 5: 744-749.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 744-749
-
-
Brabletz, T.1
Jung, A.2
Spaderna, S.3
Hlubek, F.4
Kirchner, T.5
-
6
-
-
0842325802
-
Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population
-
Brat DJ, Castellano-Sanchez AA, Hunter SB, Pecot M, Cohen C, Hammond EH, et al (2004) Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population. Cancer Res 64: 920-927.
-
(2004)
Cancer Res
, vol.64
, pp. 920-927
-
-
Brat, D.J.1
Castellano-Sanchez, A.A.2
Hunter, S.B.3
Pecot, M.4
Cohen, C.5
Hammond, E.H.6
-
7
-
-
84879983245
-
Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity
-
Chaffer CL, Marjanovic ND, Lee T, Bell G, Kleer CG, Reinhardt F, et al (2013) Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell 154: 61-74.
-
(2013)
Cell
, vol.154
, pp. 61-74
-
-
Chaffer, C.L.1
Marjanovic, N.D.2
Lee, T.3
Bell, G.4
Kleer, C.G.5
Reinhardt, F.6
-
8
-
-
79952283482
-
P53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
-
Chang C-J, Chao C-H, Xia W, Yang J-Y, Xiong Y, Li CW, et al (2011) p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol 13: 317-323.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 317-323
-
-
Chang, C.-J.1
Chao, C.-H.2
Xia, W.3
Yang, J.-Y.4
Xiong, Y.5
Li, C.W.6
-
9
-
-
84864717408
-
VHL regulates the effects of MIR-23b on glioma survival and invasion via suppression of HIF-1α/VEGF and β-catenin/Tcf-4 signaling
-
Chen L, Han L, Zhang K, Shi Z, Zhang J, Zhang A, et al (2012) VHL regulates the effects of miR-23b on glioma survival and invasion via suppression of HIF-1α/VEGF and β-catenin/Tcf-4 signaling. Neuro-Oncol 14: 1026-1036.
-
(2012)
Neuro-Oncol
, vol.14
, pp. 1026-1036
-
-
Chen, L.1
Han, L.2
Zhang, K.3
Shi, Z.4
Zhang, J.5
Zhang, A.6
-
10
-
-
0345307701
-
Expression of Zfhep/deltaEF1 protein in palate, neural progenitors, and differentiated neurons
-
Darling DS, Stearman RP, Qi Y, Qiu MS, Feller JP, (2003) Expression of Zfhep/deltaEF1 protein in palate, neural progenitors, and differentiated neurons. Gene Expr Patterns 3: 709-717.
-
(2003)
Gene Expr Patterns
, vol.3
, pp. 709-717
-
-
Darling, D.S.1
Stearman, R.P.2
Qi, Y.3
Qiu, M.S.4
Feller, J.P.5
-
11
-
-
33644873765
-
TWIST is expressed in human gliomas and promotes invasion
-
Elias MC, Tozer KR, Silber JR, Mikheeva S, Deng M, Morrison RS, et al (2005) TWIST is expressed in human gliomas and promotes invasion. Neoplasia 7: 824-837.
-
(2005)
Neoplasia
, vol.7
, pp. 824-837
-
-
Elias, M.C.1
Tozer, K.R.2
Silber, J.R.3
Mikheeva, S.4
Deng, M.5
Morrison, R.S.6
-
12
-
-
84880182849
-
CXCR7 is induced by hypoxia and mediates glioma cell migration towards SDF-1α
-
Esencay M, Sarfraz Y, Zagzag D, (2013) CXCR7 is induced by hypoxia and mediates glioma cell migration towards SDF-1α. BMC Cancer 13: 347.
-
(2013)
BMC Cancer
, vol.13
, pp. 347
-
-
Esencay, M.1
Sarfraz, Y.2
Zagzag, D.3
-
13
-
-
34247847903
-
Silencing hypoxia-inducible factor-1alpha inhibits cell migration and invasion under hypoxic environment in malignant gliomas
-
Fujiwara S, Nakagawa K, Harada H, Nagato S, Furukawa K, Teraoka M, et al (2007) Silencing hypoxia-inducible factor-1alpha inhibits cell migration and invasion under hypoxic environment in malignant gliomas. Int J Oncol 30: 793-802.
-
(2007)
Int J Oncol
, vol.30
, pp. 793-802
-
-
Fujiwara, S.1
Nakagawa, K.2
Harada, H.3
Nagato, S.4
Furukawa, K.5
Teraoka, M.6
-
14
-
-
73749085142
-
Inhibition of tissue factor/protease-activated receptor-2 signaling limits proliferation, migration and invasion of malignant glioma cells
-
Gessler F, Voss V, Dützmann S, Seifert V, Gerlach R, Kögel D, (2010) Inhibition of tissue factor/protease-activated receptor-2 signaling limits proliferation, migration and invasion of malignant glioma cells. Neuroscience 165: 1312-1322.
-
(2010)
Neuroscience
, vol.165
, pp. 1312-1322
-
-
Gessler, F.1
Voss, V.2
Dützmann, S.3
Seifert, V.4
Gerlach, R.5
Kögel, D.6
-
15
-
-
79955954699
-
An autocrine TGF-beta/ZEB/MIR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition
-
Gregory PA, Bracken CP, Smith E, Bert AG, Wright JA, Roslan S, et al (2011) An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol Biol Cell 22: 1686-1698.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 1686-1698
-
-
Gregory, P.A.1
Bracken, C.P.2
Smith, E.3
Bert, A.G.4
Wright, J.A.5
Roslan, S.6
-
16
-
-
79955559699
-
Snai1 is involved in the proliferation and migration of glioblastoma cells
-
Han S-P, Kim J-H, Han M-E, Sim H-E, Kim K-S, Yoon S, et al (2011) Snai1 is involved in the proliferation and migration of glioblastoma cells. Cell Mol Neurobiol 31: 489-496.
-
(2011)
Cell Mol Neurobiol
, vol.31
, pp. 489-496
-
-
Han, S.-P.1
Kim, J.-H.2
Han, M.-E.3
Sim, H.-E.4
Kim, K.-S.5
Yoon, S.6
-
17
-
-
84858202435
-
"go or grow": The key to the emergence of invasion in tumour progression?
-
Hatzikirou H, Basanta D, Simon M, Schaller K, Deutsch A, (2012) "Go or grow": the key to the emergence of invasion in tumour progression? Math Med Biol 29: 49-65.
-
(2012)
Math Med Biol
, vol.29
, pp. 49-65
-
-
Hatzikirou, H.1
Basanta, D.2
Simon, M.3
Schaller, K.4
Deutsch, A.5
-
18
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens A-C, Gorlia T, Hamou M-F, de Tribolet N, Weller M, et al (2005) MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352: 997-1003.
-
(2005)
N Engl J Med
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.-C.2
Gorlia, T.3
Hamou, M.-F.4
De Tribolet, N.5
Weller, M.6
-
19
-
-
84871385387
-
ZEB/MIR-200 feedback loop: At the crossroads of signal transduction in cancer
-
Hill L, Browne G, Tulchinsky E, (2013) ZEB/miR-200 feedback loop: at the crossroads of signal transduction in cancer. Int J Cancer 132: 745-754.
-
(2013)
Int J Cancer
, vol.132
, pp. 745-754
-
-
Hill, L.1
Browne, G.2
Tulchinsky, E.3
-
20
-
-
84862762917
-
The "go or grow" potential of gliomas is linked to the neuropeptide processing enzyme carboxypeptidase e and mediated by metabolic stress
-
Höring E, Harter PN, Seznec J, Schittenhelm J, Bühring H-J, Bhattacharyya S, et al (2012) The "go or grow" potential of gliomas is linked to the neuropeptide processing enzyme carboxypeptidase e and mediated by metabolic stress. Acta Neuropathol (Berl) 124: 83-97.
-
(2012)
Acta Neuropathol (Berl)
, vol.124
, pp. 83-97
-
-
Höring, E.1
Harter, P.N.2
Seznec, J.3
Schittenhelm, J.4
Bühring, H.-J.5
Bhattacharyya, S.6
-
21
-
-
65249131228
-
Brain tumor hypoxia: Tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target
-
Jensen RL, (2009) Brain tumor hypoxia: tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target. J Neurooncol 92: 317-335.
-
(2009)
J Neurooncol
, vol.92
, pp. 317-335
-
-
Jensen, R.L.1
-
22
-
-
84870813786
-
Resistance to hypoxia-induced, BNIP3-mediated cell death contributes to an increase in a CD133-positive cell population in human glioblastomas in vitro
-
Kahlert UD, Maciaczyk D, Dai F, Claus R, Firat E, Doostkam S, et al (2012) Resistance to hypoxia-induced, BNIP3-mediated cell death contributes to an increase in a CD133-positive cell population in human glioblastomas in vitro. J Neuropathol Exp Neurol 71: 1086-1099.
-
(2012)
J Neuropathol Exp Neurol
, vol.71
, pp. 1086-1099
-
-
Kahlert, U.D.1
Maciaczyk, D.2
Dai, F.3
Claus, R.4
Firat, E.5
Doostkam, S.6
-
23
-
-
84865302520
-
Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition
-
Kahlert UD, Maciaczyk D, Doostkam S, Orr BA, Simons B, Bogiel T, et al (2012) Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition. Cancer Lett 325: 42-53.
-
(2012)
Cancer Lett
, vol.325
, pp. 42-53
-
-
Kahlert, U.D.1
Maciaczyk, D.2
Doostkam, S.3
Orr, B.A.4
Simons, B.5
Bogiel, T.6
-
24
-
-
84875364615
-
Epithelial-to-mesenchymal(-like) transition as a relevant molecular event in malignant gliomas
-
Kahlert UD, Nikkhah G, Maciaczyk J, (2013) Epithelial-to-mesenchymal(-like) transition as a relevant molecular event in malignant gliomas. Cancer Lett 331: 131-138.
-
(2013)
Cancer Lett
, vol.331
, pp. 131-138
-
-
Kahlert, U.D.1
Nikkhah, G.2
Maciaczyk, J.3
-
25
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
Kalluri R, Weinberg RA, (2009) The basics of epithelial-mesenchymal transition. J Clin Invest 119: 1420-1428.
-
(2009)
J Clin Invest
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
26
-
-
34247527730
-
Hypoxia-inducible factors, stem cells, and cancer
-
Keith B, Simon MC, (2007) Hypoxia-inducible factors, stem cells, and cancer. Cell 129: 465-472.
-
(2007)
Cell
, vol.129
, pp. 465-472
-
-
Keith, B.1
Simon, M.C.2
-
27
-
-
47249091921
-
The MIR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
-
Korpal M, Lee ES, Hu G, Kang Y, (2008) The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem 283: 14910-14914.
-
(2008)
J Biol Chem
, vol.283
, pp. 14910-14914
-
-
Korpal, M.1
Lee, E.S.2
Hu, G.3
Kang, Y.4
-
28
-
-
0037374289
-
Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1
-
Krishnamachary B, Berg-Dixon S, Kelly B, Agani F, Feldser D, Ferreira G, et al (2003) Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1. Cancer Res 63: 1138-1143.
-
(2003)
Cancer Res
, vol.63
, pp. 1138-1143
-
-
Krishnamachary, B.1
Berg-Dixon, S.2
Kelly, B.3
Agani, F.4
Feldser, D.5
Ferreira, G.6
-
29
-
-
65749106405
-
Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
-
Li Z, Bao S, Wu Q, Wang H, Eyler C, Sathornsumetee S, et al (2009) Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 15: 501-513.
-
(2009)
Cancer Cell
, vol.15
, pp. 501-513
-
-
Li, Z.1
Bao, S.2
Wu, Q.3
Wang, H.4
Eyler, C.5
Sathornsumetee, S.6
-
30
-
-
84883870483
-
Clinical neurotransplantation protocol for Huntington's and Parkinson's disease
-
Lopez WOC, Nikkhah G, Kahlert UD, Maciaczyk D, Bogiel T, Moellers S, et al (2013) Clinical neurotransplantation protocol for Huntington's and Parkinson's disease. Restor Neurol Neurosci 31: 579-595.
-
(2013)
Restor Neurol Neurosci
, vol.31
, pp. 579-595
-
-
Lopez, W.O.C.1
Nikkhah, G.2
Kahlert, U.D.3
Maciaczyk, D.4
Bogiel, T.5
Moellers, S.6
-
31
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, et al (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol (Berl) 114: 97-109.
-
(2007)
Acta Neuropathol (Berl)
, vol.114
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
Cavenee, W.K.4
Burger, P.C.5
Jouvet, A.6
-
32
-
-
79951825517
-
Mouse snail is a target gene for HIF
-
Luo D, Wang J, Li J, Post M, (2011) Mouse snail is a target gene for HIF. Mol Cancer Res 9: 234-245.
-
(2011)
Mol Cancer Res
, vol.9
, pp. 234-245
-
-
Luo, D.1
Wang, J.2
Li, J.3
Post, M.4
-
33
-
-
84899426379
-
Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant glioma
-
Mahabir R, Tanino M, Elmansuri A, Wang L, Kimura T, Kimura T, et al (2014) Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant glioma. Neuro-Oncol 16: 671-685.
-
(2014)
Neuro-Oncol
, vol.16
, pp. 671-685
-
-
Mahabir, R.1
Tanino, M.2
Elmansuri, A.3
Wang, L.4
Kimura, T.5
Kimura, T.6
-
34
-
-
84884229397
-
LIN28a facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program
-
Mao X, Hütt-Cabezas M, Orr BA, Weingart M, Taylor I, Rajan AK, et al (2013) LIN28a facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program. Oncotarget 4: 1050-1064.
-
(2013)
Oncotarget
, vol.4
, pp. 1050-1064
-
-
Mao, X.1
Hütt-Cabezas, M.2
Orr, B.A.3
Weingart, M.4
Taylor, I.5
Rajan, A.K.6
-
35
-
-
77952863838
-
Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres
-
Méndez O, Zavadil J, Esencay M, Lukyanov Y, Santovasi D, Wang SC, et al (2010) Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres. Mol Cancer 9: 133.
-
(2010)
Mol Cancer
, vol.9
, pp. 133
-
-
Méndez, O.1
Zavadil, J.2
Esencay, M.3
Lukyanov, Y.4
Santovasi, D.5
Wang, S.C.6
-
36
-
-
77954674187
-
TWIST1 promotes invasion through mesenchymal change in human glioblastoma
-
Mikheeva SA, Mikheev AM, Petit A, Beyer R, Oxford RG, Khorasani L, et al (2010) TWIST1 promotes invasion through mesenchymal change in human glioblastoma. Mol Cancer 9: 194.
-
(2010)
Mol Cancer
, vol.9
, pp. 194
-
-
Mikheeva, S.A.1
Mikheev, A.M.2
Petit, A.3
Beyer, R.4
Oxford, R.G.5
Khorasani, L.6
-
37
-
-
77956224494
-
Oxygen in stem cell biology: A critical component of the stem cell niche
-
Mohyeldin A, Garzõn-Muvdi T, Quiñones-Hinojosa A, (2010) Oxygen in stem cell biology: a critical component of the stem cell niche. Cell Stem Cell 7: 150-161.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 150-161
-
-
Mohyeldin, A.1
Garzõn-Muvdi, T.2
Quiñones-Hinojosa, A.3
-
38
-
-
84865473036
-
Transcriptional factors for epithelial-mesenchymal transition are associated with mesenchymal differentiation in gliosarcoma
-
Nagaishi M, Paulus W, Brokinkel B, Vital A, Tanaka Y, Nakazato Y, et al (2012) Transcriptional factors for epithelial-mesenchymal transition are associated with mesenchymal differentiation in gliosarcoma. Brain Pathol 22: 670-676.
-
(2012)
Brain Pathol
, vol.22
, pp. 670-676
-
-
Nagaishi, M.1
Paulus, W.2
Brokinkel, B.3
Vital, A.4
Tanaka, Y.5
Nakazato, Y.6
-
39
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Pàez-Ribes M, Allen E, Hudock J, Takeda T, Okuyama H, Viñals F, et al (2009) Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 15: 220-231.
-
(2009)
Cancer Cell
, vol.15
, pp. 220-231
-
-
Pàez-Ribes, M.1
Allen, E.2
Hudock, J.3
Takeda, T.4
Okuyama, H.5
Viñals, F.6
-
40
-
-
0037478437
-
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
-
Pennacchietti S, Michieli P, Galluzzo M, Mazzone M, Giordano S, Comoglio PM, (2003) Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. Cancer Cell 3: 347-361.
-
(2003)
Cancer Cell
, vol.3
, pp. 347-361
-
-
Pennacchietti, S.1
Michieli, P.2
Galluzzo, M.3
Mazzone, M.4
Giordano, S.5
Comoglio, P.M.6
-
41
-
-
84868011381
-
Function of carbonic anhydrase IX in glioblastoma multiforme
-
Proescholdt MA, Merrill MJ, Stoerr E-M, Lohmeier A, Pohl F, Brawanski A, (2012) Function of carbonic anhydrase IX in glioblastoma multiforme. Neuro-Oncol 14: 1357-1366.
-
(2012)
Neuro-Oncol
, vol.14
, pp. 1357-1366
-
-
Proescholdt, M.A.1
Merrill, M.J.2
Stoerr, E.-M.3
Lohmeier, A.4
Pohl, F.5
Brawanski, A.6
-
42
-
-
82755198488
-
β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness
-
Sánchez-Tillõ E, de Barrios O, Siles L, Cuatrecasas M, Castells A, Postigo A, (2011) β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness. Proc Natl Acad Sci U S A 108: 19204-19209.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 19204-19209
-
-
Sánchez-Tillõ, E.1
De Barrios, O.2
Siles, L.3
Cuatrecasas, M.4
Castells, A.5
Postigo, A.6
-
43
-
-
84892385077
-
The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma
-
Sánchez-Tillõ E, Fanlo L, Siles L, Montes-Moreno S, Moros A, Chiva-Blanch G, et al (2014) The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma. Cell Death Differ 21: 247-257.
-
(2014)
Cell Death Differ
, vol.21
, pp. 247-257
-
-
Sánchez-Tillõ, E.1
Fanlo, L.2
Siles, L.3
Montes-Moreno, S.4
Moros, A.5
Chiva-Blanch, G.6
-
44
-
-
67649446851
-
SNS-032 prevents hypoxia-mediated glioblastoma cell invasion by inhibiting hypoxia inducible factor-1α expression
-
Ali MA, Reis A, Ding LH, Story MD, Habib AA, Chattopadhyay A, Saha D, (2009) SNS-032 prevents hypoxia-mediated glioblastoma cell invasion by inhibiting hypoxia inducible factor-1α expression. Int J Oncol 34: 1051-1060.
-
(2009)
Int J Oncol
, vol.34
, pp. 1051-1060
-
-
Ali, M.A.1
Reis, A.2
Ding, L.H.3
Story, M.D.4
Habib, A.A.5
Chattopadhyay, A.6
Saha, D.7
-
45
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
Sarbassov DD, Guertin DA, Ali SM, Sabatini DM, (2005) Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307: 1098-1101.
-
(2005)
Science
, vol.307
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
46
-
-
84888380939
-
Snail depletes the tumorigenic potential of glioblastoma
-
Savary K, Caglayan D, Caja L, Tzavlaki K, Bin Nayeem S, Bergström T, et al (2013) Snail depletes the tumorigenic potential of glioblastoma. Oncogene 32: 5409-5420.
-
(2013)
Oncogene
, vol.32
, pp. 5409-5420
-
-
Savary, K.1
Caglayan, D.2
Caja, L.3
Tzavlaki, K.4
Bin Nayeem, S.5
Bergström, T.6
-
47
-
-
84879693403
-
Effect of silencing HIF-1α on proliferation, invasion and migration of glioblastoma U87 cells
-
Shen SH, Kwan AL, Chen YY, Wang ZX, (2013) Effect of silencing HIF-1α on proliferation, invasion and migration of glioblastoma U87 cells. Neurol Sci 34: 365-371.
-
(2013)
Neurol Sci
, vol.34
, pp. 365-371
-
-
Shen, S.H.1
Kwan, A.L.2
Chen, Y.Y.3
Wang, Z.X.4
-
48
-
-
68049114782
-
Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
-
Shimono Y, Zabala M, Cho RW, Lobo N, Dalerba P, Qian D, et al (2009) Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 138: 592-603.
-
(2009)
Cell
, vol.138
, pp. 592-603
-
-
Shimono, Y.1
Zabala, M.2
Cho, R.W.3
Lobo, N.4
Dalerba, P.5
Qian, D.6
-
49
-
-
84881540768
-
The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance
-
Siebzehnrubl FA, Silver DJ, Tugertimur B, Deleyrolle LP, Siebzehnrubl D, Sarkisian MR, et al (2013) The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance. EMBO Mol Med 5: 1196-1212.
-
(2013)
EMBO Mol Med
, vol.5
, pp. 1196-1212
-
-
Siebzehnrubl, F.A.1
Silver, D.J.2
Tugertimur, B.3
Deleyrolle, L.P.4
Siebzehnrubl, D.5
Sarkisian, M.R.6
-
50
-
-
39049160267
-
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer
-
Spaderna S, Schmalhofer O, Wahlbuhl M, Dimmler A, Bauer K, Hlubek F, et al (2008) The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer. Cancer Res 68: 537-544.
-
(2008)
Cancer Res
, vol.68
, pp. 537-544
-
-
Spaderna, S.1
Schmalhofer, O.2
Wahlbuhl, M.3
Dimmler, A.4
Bauer, K.5
Hlubek, F.6
-
51
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, et al (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352: 987-996.
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.6
-
52
-
-
70350456139
-
Transcription factor Sp1 induces ADAM17 and contributes to tumor cell invasiveness under hypoxia
-
Szalad A, Katakowski M, Zheng X, Jiang F, Chopp M, (2009) Transcription factor Sp1 induces ADAM17 and contributes to tumor cell invasiveness under hypoxia. J Exp Clin Cancer Res 28: 129.
-
(2009)
J Exp Clin Cancer Res
, vol.28
, pp. 129
-
-
Szalad, A.1
Katakowski, M.2
Zheng, X.3
Jiang, F.4
Chopp, M.5
-
53
-
-
78149388926
-
Molecular diagnostics of gliomas: The clinical perspective
-
Tabatabai G, Stupp R, van den Bent MJ, Hegi ME, Tonn JC, Wick W, Weller M, (2010) Molecular diagnostics of gliomas: the clinical perspective. Acta Neuropathol (Berl) 120: 585-592.
-
(2010)
Acta Neuropathol (Berl)
, vol.120
, pp. 585-592
-
-
Tabatabai, G.1
Stupp, R.2
Van Den Bent, M.J.3
Hegi, M.E.4
Tonn, J.C.5
Wick, W.6
Weller, M.7
-
54
-
-
0023377294
-
Characteristics of an established human glioma cell line, KNS-42
-
Takeshita I, Takaki T, Kuramitsu M, Nagasaka S, Machi T, Ogawa H, et al (1987) Characteristics of an established human glioma cell line, KNS-42. Neurol Med Chir (Tokyo) 27: 581-587.
-
(1987)
Neurol Med Chir (Tokyo)
, vol.27
, pp. 581-587
-
-
Takeshita, I.1
Takaki, T.2
Kuramitsu, M.3
Nagasaka, S.4
Machi, T.5
Ogawa, H.6
-
55
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RYJ, Nieto MA, (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.J.3
Nieto, M.A.4
-
56
-
-
73049110243
-
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting micrornas
-
Wellner U, Schubert J, Burk UC, Schmalhofer O, Zhu F, Sonntag A, et al (2009) The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting micrornas. Nat Cell Biol 11: 1487-1495.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1487-1495
-
-
Wellner, U.1
Schubert, J.2
Burk, U.C.3
Schmalhofer, O.4
Zhu, F.5
Sonntag, A.6
-
57
-
-
40249113328
-
Direct regulation of TWIST by HIF-1alpha promotes metastasis
-
Yang M-H, Wu M-Z, Chiou S-H, Chen P-M, Chang S-Y, Liu CJ, et al (2008) Direct regulation of TWIST by HIF-1alpha promotes metastasis. Nat Cell Biol 10: 295-305.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 295-305
-
-
Yang, M.-H.1
Wu, M.-Z.2
Chiou, S.-H.3
Chen, P.-M.4
Chang, S.-Y.5
Liu, C.J.6
-
58
-
-
0035976788
-
Developmental and functional evidence of a role for Zfhep in neural cell development
-
Yen G, Croci A, Dowling A, Zhang S, Zoeller RT, Darling DS, (2001) Developmental and functional evidence of a role for Zfhep in neural cell development. Brain Res Mol Brain Res 96: 59-67.
-
(2001)
Brain Res Mol Brain Res
, vol.96
, pp. 59-67
-
-
Yen, G.1
Croci, A.2
Dowling, A.3
Zhang, S.4
Zoeller, R.T.5
Darling, D.S.6
-
59
-
-
33751256842
-
Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: Implications for angiogenesis and glioma cell invasion
-
Zagzag D, Lukyanov Y, Lan L, Ali MA, Esencay M, Mendez O, et al (2006) Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion. Lab Invest 86: 1221-1232.
-
(2006)
Lab Invest
, vol.86
, pp. 1221-1232
-
-
Zagzag, D.1
Lukyanov, Y.2
Lan, L.3
Ali, M.A.4
Esencay, M.5
Mendez, O.6
-
60
-
-
58149374576
-
Digoxin and other cardiac glycosides inhibit HIF-1alpha synthesis and block tumor growth
-
Zhang H, Qian DZ, Tan YS, Lee K, Gao P, Ren YR, et al (2008) Digoxin and other cardiac glycosides inhibit HIF-1alpha synthesis and block tumor growth. Proc Natl Acad Sci U S A 105: 19579-19586.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 19579-19586
-
-
Zhang, H.1
Qian, D.Z.2
Tan, Y.S.3
Lee, K.4
Gao, P.5
Ren, Y.R.6
-
61
-
-
34147169062
-
Inhibition of ADAM17 reduces hypoxia-induced brain tumor cell invasiveness
-
Zheng X, Jiang F, Katakowski M, Kalkanis SN, Hong X, Zhang X, et al (2007) Inhibition of ADAM17 reduces hypoxia-induced brain tumor cell invasiveness. Cancer Sci 98: 674-684.
-
(2007)
Cancer Sci
, vol.98
, pp. 674-684
-
-
Zheng, X.1
Jiang, F.2
Katakowski, M.3
Kalkanis, S.N.4
Hong, X.5
Zhang, X.6
-
62
-
-
84885080490
-
Geranylgeranyltransferase i regulates HIF-1α promoting glioblastoma cell migration and invasion
-
Zhou X, Liu Z, Shi Q, Jiao J, Bian W, Song X, et al (2013) Geranylgeranyltransferase I regulates HIF-1α promoting glioblastoma cell migration and invasion. J Neurooncol 112: 365-374.
-
(2013)
J Neurooncol
, vol.112
, pp. 365-374
-
-
Zhou, X.1
Liu, Z.2
Shi, Q.3
Jiao, J.4
Bian, W.5
|