Adenovirus: Epidemiology, Global Spread of Novel Serotypes, and Advances in Treatment and Prevention

Seminars in Respiratory and Critical Care Medicine

Volumn 37, Issue 4, 2016, Pages 586-602

  Lynch, Joseph P ^a   Kajon, Adriana E ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

adenovirus; cidofovir; respiratory viral infections; serotypes

Indexed keywords

ANTIVIRUS AGENT; VIRUS VACCINE; CIDOFOVIR; CYTOSINE; PHOSPHONIC ACID DERIVATIVE;

ADENOVIRIDAE; ADENOVIRUS GENOTYPE 55; ADENOVIRUS INFECTION; ADENOVIRUS SEROTYPE 14; ADENOVIRUS SEROTYPE 21; ADENOVIRUS SEROTYPE 3; ADENOVIRUS SEROTYPE 31; ADENOVIRUS SEROTYPE 37; ADENOVIRUS SEROTYPE 4; ADENOVIRUS SEROTYPE 8; ADENOVIRUS SEROTYPES 40; ADENOVIRUS SEROTYPES 41; ARTICLE; BIOINFORMATICS; CLINICAL FEATURE; CLINICAL TRIAL (TOPIC); CONGENITAL DISORDER; GASTROINTESTINAL DISEASE; GENE SEQUENCE; GENOTYPE; GRAFT RECIPIENT; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN ADENOVIRUS 1; HUMAN ADENOVIRUS 2; HUMAN ADENOVIRUS 7; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE DEFICIENCY; IMMUNOCOMPETENCE; INFECTION PREVENTION; KERATOCONJUNCTIVITIS; NONHUMAN; ORGAN TRANSPLANTATION; PHASE 3 CLINICAL TRIAL (TOPIC); POPULATION RISK; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SEROTYPE; SOLDIER; URINARY TRACT DISEASE; VIRAL RESPIRATORY TRACT INFECTION; VIROLOGY; VIRUS CHARACTERIZATION; VIRUS GENOME; ADULT; ANALOGS AND DERIVATIVES; CHILD; CLASSIFICATION; HUMAN ADENOVIRUS INFECTION; PROSPECTIVE STUDY; RESPIRATORY TRACT INFECTION; SUPPLY AND DISTRIBUTION;

ADENOVIRIDAE; ADENOVIRIDAE INFECTIONS; ADENOVIRUS INFECTIONS, HUMAN; ADULT; ANTIVIRAL AGENTS; CHILD; CYTOSINE; HUMANS; MILITARY PERSONNEL; ORGANOPHOSPHONATES; PROSPECTIVE STUDIES; RESPIRATORY TRACT INFECTIONS; SEROGROUP; VIRAL VACCINES;

EID: 84982677750     PISSN: 10693424     EISSN: 10989048     Source Type: Journal    
DOI: 10.1055/s-0036-1584923     Document Type: Article

References (325)

1. Lynch J. P. III, Fishbein M., Echavarria M. Adenovirus. Semin Respir Crit Care Med: 2011; 32 4 494 511
2. Ison M. G. Adenovirus infections in transplant recipients. Clin Infect Dis: 2006; 43 3 331 339
3. Chang S. Y., Lee C. N., Lin P. H., et al. A community-derived outbreak of adenovirus type 3 in children in Taiwan between 2004 and 2005. J Med Virol: 2008; 80 1 102 112
4. Sandkovsky U., Vargas L., Florescu D. F. Adenovirus: current epidemiology and emerging approaches to prevention and treatment. Curr Infect Dis Rep: 2014; 16 8 416
5. Yeung R., Eshaghi A., Lombos E., et al. Characterization of culture-positive adenovirus serotypes from respiratory specimens in Toronto, Ontario, Canada: September 2007-June 2008. Virol J: 2009; 6 11
6. Mitchell L. S., Taylor B., Reimels W., Barrett F. F., Devincenzo J. P. Adenovirus 7a: a community-acquired outbreak in a children's hospital. Pediatr Infect Dis J: 2000; 19 10 996 1000
7. Kojaoghlanian T., Flomenberg P., Horwitz M. S. The impact of adenovirus infection on the immunocompromised host. Rev Med Virol: 2003; 13 3 155 171
8. Chemaly R. F., Ghosh S., Bodey G. P., et al. Respiratory viral infections in adults with hematologic malignancies and human stem cell transplantation recipients: a retrospective study at a major cancer center. Medicine (Baltimore): 2006; 85 5 278 287
9. Kim Y-J, Boeckh M., Englund J. A. Community respiratory virus infections in immunocompromised patients: hematopoietic stem cell and solid organ transplant recipients, and individuals with human immunodeficiency virus infection. Semin Respir Crit Care Med: 2007; 28 2 222 242
10. Moura P. O., Roberto A. F., Hein N., et al. Molecular epidemiology of human adenovirus isolated from children hospitalized with acute respiratory infection in São Paulo, Brazil. J Med Virol: 2007; 79 2 174 181
11. Lin K. H., Lin Y. C., Chen H. L., et al. A two decade survey of respiratory adenovirus in Taiwan: the reemergence of adenovirus types 7 and 4. J Med Virol: 2004; 73 2 274 279
12. Li Q. G., Zheng Q. J., Liu Y. H., Wadell G. Molecular epidemiology of adenovirus types 3 and 7 isolated from children with pneumonia in Beijing. J Med Virol: 1996; 49 3 170 177
13. Chen H. L., Chiou S. S., Hsiao H. P., et al. Respiratory adenoviral infections in children: a study of hospitalized cases in southern Taiwan in 2001-2002. J Trop Pediatr: 2004; 50 5 279 284
14. Matthes-Martin S., Feuchtinger T., Shaw P. J., et al. Fourth European Conference on Infections in Leukemia. European guidelines for diagnosis and treatment of adenovirus infection in leukemia and stem cell transplantation: summary of ECIL-4 (2011). Transpl Infect Dis: 2012; 14 6 555 563
15. Breuer S., Rauch M., Matthes-Martin S., Lion T. Molecular diagnosis and management of viral infections in hematopoietic stem cell transplant recipients. Mol Diagn Ther: 2012; 16 2 63 77
16. Kolavic-Gray S. A., Binn L. N., Sanchez J. L., et al. Large epidemic of adenovirus type 4 infection among military trainees: epidemiological, clinical, and laboratory studies. Clin Infect Dis: 2002; 35 7 808 818
17. Sanchez J. L., Binn L. N., Innis B. L., et al. Epidemic of adenovirus-induced respiratory illness among US military recruits: epidemiologic and immunologic risk factors in healthy, young adults. J Med Virol: 2001; 65 4 710 718
18. Kajon A. E., Moseley J. M., Metzgar D., et al. Molecular epidemiology of adenovirus type 4 infections in US military recruits in the postvaccination era (1997-2003). J Infect Dis: 2007; 196 1 67 75
19. Ryan M. A., Gray G. C., Smith B., McKeehan J. A., Hawksworth A. W., Malasig M. D. Large epidemic of respiratory illness due to adenovirus types 7 and 3 in healthy young adults. Clin Infect Dis: 2002; 34 5 577 582
20. Russell K. L., Hawksworth A. W., Ryan M. A., et al. Vaccine-preventable adenoviral respiratory illness in US military recruits, 1999-2004. Vaccine: 2006; 24 15 2835 2842
21. Centers for Disease Control and Prevention (CDC) Civilian outbreak of adenovirus acute respiratory disease-South Dakota, 1997. MMWR Morb Mortal Wkly Rep: 1998; 47 27 567 570
22. Zarraga A. L., Kerns F. T., Kitchen L. W. Adenovirus pneumonia with severe sequelae in an immunocompetent adult. Clin Infect Dis: 1992; 15 4 712 713
23. Dudding B. A., Wagner S. C., Zeller J. A., Gmelich J. T., French G. R., Top F. H. Jr. Fatal pneumonia associated with adenovirus type 7 in three military trainees. N Engl J Med: 1972; 286 24 1289 1292
24. Louie J. K., Kajon A. E., Holodniy M., et al. Severe pneumonia due to adenovirus serotype 14: a new respiratory threat? Clin Infect Dis: 2008; 46 3 421 425
25. Neofytos D., Ojha A., Mookerjee B., et al. Treatment of adenovirus disease in stem cell transplant recipients with cidofovir. Biol Blood Marrow Transplant: 2007; 13 1 74 81
26. Zheng X., Lu X., Erdman D. D., et al. Identification of adenoviruses in specimens from high-risk pediatric stem cell transplant recipients and controls. J Clin Microbiol: 2008; 46 1 317 320
27. Symeonidis N., Jakubowski A., Pierre-Louis S., et al. Invasive adenoviral infections in T-cell-depleted allogeneic hematopoietic stem cell transplantation: high mortality in the era of cidofovir. Transpl Infect Dis: 2007; 9 2 108 113
28. Bordigoni P., Carret A. S., Venard V., Witz F., Le Faou A. Treatment of adenovirus infections in patients undergoing allogeneic hematopoietic stem cell transplantation. Clin Infect Dis: 2001; 32 9 1290 1297
29. Lu X., Erdman D. D. Molecular typing of human adenoviruses by PCR and sequencing of a partial region of the hexon gene. Arch Virol: 2006; 151 8 1587 1602
30. Henquell C., Boeuf B., Mirand A., et al. Fatal adenovirus infection in a neonate and transmission to health-care workers. J Clin Virol: 2009; 45 4 345 348
31. Lee J., Choi E. H., Lee H. J. Comprehensive serotyping and epidemiology of human adenovirus isolated from the respiratory tract of Korean children over 17 consecutive years (1991-2007). J Med Virol: 2010; 82 4 624 631
32. Jones M. S. II, Harrach B., Ganac R. D., et al. New adenovirus species found in a patient presenting with gastroenteritis. J Virol: 2007; 81 11 5978 5984
33. Kajon A. E., Lu X., Erdman D. D., et al. Molecular epidemiology and brief history of emerging adenovirus 14-associated respiratory disease in the United States. J Infect Dis: 2010; 202 1 93 103
34. Hage E., Huzly D., Ganzenmueller T., Beck R., Schulz T. F., Heim A. A human adenovirus species B subtype 21a associated with severe pneumonia. J Infect: 2014; 69 5 490 499
35. Robinson C. M., Singh G., Lee J. Y., et al. Molecular evolution of human adenoviruses. Sci Rep: 2013; 3 1812
36. Hage E., Gerd Liebert U., Bergs S., Ganzenmueller T., Heim A. Human mastadenovirus type 70: a novel, multiple recombinant species D mastadenovirus isolated from diarrhoeal faeces of a haematopoietic stem cell transplantation recipient. J Gen Virol: 2015; 96 9 2734 2742
37. Kajon A. E., Echavarria M., de Jong J. C. Designation of human adenovirus types based on sequence data: an unfinished debate. J Clin Virol: 2013; 58 4 743 744
38. Echavarría M. Adenoviruses in immunocompromised hosts. Clin Microbiol Rev: 2008; 21 4 704 715
39. Kajon A. E., Hang J., Hawksworth A., et al. Molecular Epidemiology of Adenovirus Type 21 Respiratory Strains Isolated From US Military Trainees (1996-2014). J Infect Dis: 2015; 212 6 871 880
40. Erdman D. D., Xu W., Gerber S. I., et al. Molecular epidemiology of adenovirus type 7 in the United States, 1966-2000. Emerg Infect Dis: 2002; 8 3 269 277
41. Houng H. S., Gong H., Kajon A. E., et al. Genome sequences of human adenovirus 14 isolates from mild respiratory cases and a fatal pneumonia, isolated during 2006-2007 epidemics in North America. Respir Res: 2010; 11 116
42. Ebner K., Rauch M., Preuner S., Lion T. Typing of human adenoviruses in specimens from immunosuppressed patients by PCR-fragment length analysis and real-time quantitative PCR. J Clin Microbiol: 2006; 44 8 2808 2815
43. Walls T., Hawrami K., Ushiro-Lumb I., Shingadia D., Saha V., Shankar A. G. Adenovirus infection after pediatric bone marrow transplantation: is treatment always necessary? Clin Infect Dis: 2005; 40 9 1244 1249
44. Kajon A. E., Dickson L. M., Metzgar D., Houng H. S., Lee V., Tan B. H. Outbreak of febrile respiratory illness associated with adenovirus 11a infection in a Singapore military training cAMP. J Clin Microbiol: 2010; 48 4 1438 1441
45. Nakayama M., Miyazaki C., Ueda K., et al. Pharyngoconjunctival fever caused by adenovirus type 11. Pediatr Infect Dis J: 1992; 11 1 6 9
46. Yin-Murphy M., Lim K. H., Chua P. H. Adenovirus type 11 epidemic conjunctivitis in Singapore. Southeast Asian J Trop Med Public Health: 1974; 5 3 333 341
47. Tai F. H., Chu S., Chi W. H., Wei H. Y., Hierholzer J. C. Epidemic haemorrhagic conjunctivitis associated with adenovirus type 11 in Taiwan. Southeast Asian J Trop Med Public Health: 1974; 5 3 342 349
48. James L., Vernon M. O., Jones R. C., et al. Outbreak of human adenovirus type 3 infection in a pediatric long-term care facility-Illinois, 2005. Clin Infect Dis: 2007; 45 4 416 420
49. Ishiko H., Aoki K. Spread of epidemic keratoconjunctivitis due to a novel serotype of human adenovirus in Japan. J Clin Microbiol: 2009; 47 8 2678 2679
50. Filho E. P., da Costa Faria N. R., Fialho A. M., et al. Adenoviruses associated with acute gastroenteritis in hospitalized and community children up to 5 years old in Rio de Janeiro and Salvador, Brazil. J Med Microbiol: 2007; 56 Pt 3 313 319
51. Madisch I., Wölfel R., Harste G., Pommer H., Heim A. Molecular identification of adenovirus sequences: a rapid scheme for early typing of human adenoviruses in diagnostic samples of immunocompetent and immunodeficient patients. J Med Virol: 2006; 78 9 1210 1217
52. Hársi C. M., Rolim D. P., Gomes S. A., et al. Adenovirus genome types isolated from stools of children with gastroenteritis in São Paulo, Brazil. J Med Virol: 1995; 45 2 127 134
53. Fukuda S., Kuwayama M., Takao S., Shimazu Y., Miyazaki K. Molecular epidemiology of subgenus F adenoviruses associated with pediatric gastroenteritis during eight years in Hiroshima Prefecture as a limited area. Arch Virol: 2006; 151 12 2511 2517
54. Sdiri-Loulizi K., Gharbi-Khelifi H., de Rougemont A., et al. Molecular epidemiology of human astrovirus and adenovirus serotypes 40/41 strains related to acute diarrhea in Tunisian children. J Med Virol: 2009; 81 11 1895 1902
55. Magwalivha M., Wolfaardt M., Kiulia N. M., van Zyl W. B., Mwenda J. M., Taylor M. B. High prevalence of species D human adenoviruses in fecal specimens from Urban Kenyan children with diarrhea. J Med Virol: 2010; 82 1 77 84
56. Gonçalves G., Gouveia E., Mesquita J. R., et al. Outbreak of acute gastroenteritis caused by adenovirus type 41 in a kindergarten. Epidemiol Infect: 2011; 139 11 1672 1675
57. Li L., Shimizu H., Doan L. T., et al. Characterizations of adenovirus type 41 isolates from children with acute gastroenteritis in Japan, Vietnam, and Korea. J Clin Microbiol: 2004; 42 9 4032 4039
58. Marie-Cardine A., Gourlain K., Mouterde O., et al. Epidemiology of acute viral gastroenteritis in children hospitalized in Rouen, France. Clin Infect Dis: 2002; 34 9 1170 1178
59. Soares C. C., Volotão E. M., Albuquerque M. C., et al. Prevalence of enteric adenoviruses among children with diarrhea in four Brazilian cities. J Clin Virol: 2002; 23 3 171 177
60. Cunliffe N. A., Booth J. A., Elliot C., et al. Healthcare-associated viral gastroenteritis among children in a large pediatric hospital, United Kingdom. Emerg Infect Dis: 2010; 16 1 55 62
61. Iturriza Gómara M., Simpson R., Perault A. M., et al. Structured surveillance of infantile gastroenteritis in East Anglia, UK: incidence of infection with common viral gastroenteric pathogens. Epidemiol Infect: 2008; 136 1 23 33
62. King J. C. Jr. Community respiratory viruses in individuals with human immunodeficiency virus infection. Am J Med: 1997; 102 (3A): 19 24, discussion 25-26
63. Wigger H. J., Blanc W. A. Fatal hepatic and bronchial necrosis in adenovirus infection with thymic alymphoplasia. N Engl J Med: 1966; 275 16 870 874
64. Dagan R., Schwartz R. H., Insel R. A., Menegus M. A. Severe diffuse adenovirus 7a pneumonia in a child with combined immunodeficiency: possible therapeutic effect of human immune serum globulin containing specific neutralizing antibody. Pediatr Infect Dis: 1984; 3 3 246 251
65. Barker J. H., Luby J. P., Sean Dalley A., Bartek W. M., Burns D. K., Erdman D. D. Fatal type 3 adenoviral pneumonia in immunocompetent adult identical twins. Clin Infect Dis: 2003; 37 10 e142 e146
66. Buffington J., Chapman L. E., Stobierski M. G., et al. Epidemic keratoconjunctivitis in a chronic care facility: risk factors and measures for control. J Am Geriatr Soc: 1993; 41 11 1177 1181
67. Singh-Naz N., Brown M., Ganeshananthan M. Nosocomial adenovirus infection: molecular epidemiology of an outbreak. Pediatr Infect Dis J: 1993; 12 11 922 925
68. Lessa F. C., Gould P. L., Pascoe N., et al. Health care transmission of a newly emergent adenovirus serotype in health care personnel at a military hospital in Texas, 2007. J Infect Dis: 2009; 200 11 1759 1765
69. Russell K. L., Broderick M. P., Franklin S. E., et al. Transmission dynamics and prospective environmental sampling of adenovirus in a military recruit setting. J Infect Dis: 2006; 194 7 877 885
70. Garnett C. T., Erdman D., Xu W., Gooding L. R. Prevalence and quantitation of species C adenovirus DNA in human mucosal lymphocytes. J Virol: 2002; 76 21 10608 10616
71. Bil-Lula I., Ussowicz M., Rybka B., et al. Hematuria due to adenoviral infection in bone marrow transplant recipients. Transplant Proc: 2010; 42 9 3729 3734
72. Wadell G. Molecular epidemiology of human adenoviruses. Curr Top Microbiol Immunol: 1984; 110 191 220
73. Mattner F., Sykora K. W., Meissner B., Heim A. An adenovirus type F41 outbreak in a pediatric bone marrow transplant unit: analysis of clinical impact and preventive strategies. Pediatr Infect Dis J: 2008; 27 5 419 424
74. McNeill K. M., Ridgely Benton F., Monteith S. C., Tuchscherer M. A., Gaydos J. C. Epidemic spread of adenovirus type 4-associated acute respiratory disease between U.S. Army installations. Emerg Infect Dis: 2000; 6 4 415 419
75. Jeon K., Kang C. I., Yoon C. H., et al. High isolation rate of adenovirus serotype 7 from South Korean military recruits with mild acute respiratory disease. Eur J Clin Microbiol Infect Dis: 2007; 26 7 481 483
76. Padin D. S., Faix D., Brodine S., et al. Retrospective analysis of demographic and clinical factors associated with etiology of febrile respiratory illness among US military basic trainees. BMC Infect Dis: 2014; 14 576
77. Sanchez M. P., Erdman D. D., Torok T. J., Freeman C. J., Matyas B. T. Outbreak of adenovirus 35 pneumonia among adult residents and staff of a chronic care psychiatric facility. J Infect Dis: 1997; 176 3 760 763
78. Finn A., Anday E., Talbot G. H. An epidemic of adenovirus 7a infection in a neonatal nursery: course, morbidity, and management. Infect Control Hosp Epidemiol: 1988; 9 9 398 404
79. Klinger J. R., Sanchez M. P., Curtin L. A., Durkin M., Matyas B. Multiple cases of life-threatening adenovirus pneumonia in a mental health care center. Am J Respir Crit Care Med: 1998; 157 2 645 649
80. Gerber S. I., Erdman D. D., Pur S. L., et al. Outbreak of adenovirus genome type 7d2 infection in a pediatric chronic-care facility and tertiary-care hospital. Clin Infect Dis: 2001; 32 5 694 700
81. Zhu Z., Zhang Y., Xu S., et al. Outbreak of acute respiratory disease in China caused by B2 species of adenovirus type 11. J Clin Microbiol: 2009; 47 3 697 703
82. Harris D. J., Wulff H., Ray C. G., Poland J. D., Chin T. D., Wenner H. A. Viruses and disease. 3. An outbreak of adenovirus type 7A in a children's home. Am J Epidemiol: 1971; 93 5 399 402
83. Chany C., Lepine P., Lelong M., Le T. V., Satge P., Virat J. Severe and fatal pneumonia in infants and young children associated with adenovirus infections. Am J Hyg: 1958; 67 3 367 378
84. Schmitz H., Wigand R., Heinrich W. Worldwide epidemiology of human adenovirus infections. Am J Epidemiol: 1983; 117 4 455 466
85. Rubin B. A. Clinical picture and epidemiology of adenovirus infections (a review). Acta Microbiol Hung: 1993; 40 4 303 323
86. Trei J. S., Johns N. M., Garner J. L., et al. Spread of adenovirus to geographically dispersed military installations, May-October 2007. Emerg Infect Dis: 2010; 16 5 769 775
87. Sauerbrei A., Sehr K., Brandstädt A., Heim A., Reimer K., Wutzler P. Sensitivity of human adenoviruses to different groups of chemical biocides. J Hosp Infect: 2004; 57 1 59 66
88. Hong J. Y., Lee H. J., Piedra P. A., et al. Lower respiratory tract infections due to adenovirus in hospitalized Korean children: epidemiology, clinical features, and prognosis. Clin Infect Dis: 2001; 32 10 1423 1429
89. Lu Q. B., Tong Y. G., Wo Y., et al. Epidemiology of human adenovirus and molecular characterization of human adenovirus 55 in China, 2009-2012. Influenza Other Respi Viruses: 2014; 8 3 302 308
90. Hakim F. A., Tleyjeh I. M. Severe adenovirus pneumonia in immunocompetent adults: a case report and review of the literature. Eur J Clin Microbiol Infect Dis: 2008; 27 2 153 158
91. Cao B., Huang G. H., Pu Z. H., et al. Emergence of community-acquired adenovirus type 55 as a cause of community-onset pneumonia. Chest: 2014; 145 1 79 86
92. Sly P. D., Soto-Quiros M. E., Landau L. I., Hudson I., Newton-John H. Factors predisposing to abnormal pulmonary function after adenovirus type 7 pneumonia. Arch Dis Child: 1984; 59 10 935 939
93. Cherry J. Adenoviruses. In: Feigin R. D., Cherry J. D., Demmler G. J., Kaplan S. L., eds. Textbook of Pediatric Infectious Diseases, 5th ed. Vol. 2. Philadelphia Saunders: 2003; 1843 1856
94. Becroft D. M. Bronchiolitis obliterans, bronchiectasis, and other sequelae of adenovirus type 21 infection in young children. J Clin Pathol: 1971; 24 1 72 82
95. Kalu S. U., Loeffelholz M., Beck E., et al. Persistence of adenovirus nucleic acids in nasopharyngeal secretions: a diagnostic conundrum. Pediatr Infect Dis J: 2010; 29 8 746 750
96. Macek V., Sorli J., Kopriva S., Marin J. Persistent adenoviral infection and chronic airway obstruction in children. Am J Respir Crit Care Med: 1994; 150 1 7 10
97. Wurzel D. F., Marchant J. M., Yerkovich S. T., et al. Prospective characterization of protracted bacterial bronchitis in children. Chest: 2014; 145 6 1271 1278
98. Wurzel D. F., Mackay I. M., Marchant J. M., et al. Adenovirus species C is associated with chronic suppurative lung diseases in children. Clin Infect Dis: 2014; 59 1 34 40
99. Wurzel D. F., Marchant J. M., Clark J. E., et al. Respiratory virus detection in nasopharyngeal aspirate versus bronchoalveolar lavage is dependent on virus type in children with chronic respiratory symptoms. J Clin Virol: 2013; 58 4 683 688
100. Elliott W. M., Hayashi S., Hogg J. C. Immunodetection of adenoviral E1A proteins in human lung tissue. Am J Respir Cell Mol Biol: 1995; 12 6 642 648
101. Matsuse T., Hayashi S., Kuwano K., Keunecke H., Jefferies W. A., Hogg J. C. Latent adenoviral infection in the pathogenesis of chronic airways obstruction. Am Rev Respir Dis: 1992; 146 1 177 184
102. Percivalle E., Sarasini A., Torsellini M., et al. A comparison of methods for detecting adenovirus type 8 keratoconjunctivitis during a nosocomial outbreak in a Neonatal Intensive Care Unit. J Clin Virol: 2003; 28 3 257 264
103. Hamada N., Gotoh K., Hara K., et al. Nosocomial outbreak of epidemic keratoconjunctivitis accompanying environmental contamination with adenoviruses. J Hosp Infect: 2008; 68 3 262 268
104. Ishiko H., Shimada Y., Konno T., et al. Novel human adenovirus causing nosocomial epidemic keratoconjunctivitis. J Clin Microbiol: 2008; 46 6 2002 2008
105. Tabbara K. F., Omar N., Hammouda E., et al. Molecular epidemiology of adenoviral keratoconjunctivitis in Saudi Arabia. Mol Vis: 2010; 16 2132 2136
106. Aoki K., Tagawa Y. A twenty-one year surveillance of adenoviral conjunctivitis in Sapporo, Japan. Int Ophthalmol Clin: 2002; 42 1 49 54
107. Chang C. H., Lin K. H., Sheu M. M., Huang W. L., Wang H. Z., Chen C. W. The change of etiological agents and clinical signs of epidemic viral conjunctivitis over an 18-year period in southern Taiwan. Graefes Arch Clin Exp Ophthalmol: 2003; 241 7 554 560
108. Matsui K., Saha S., Saitoh M., et al. Isolation and identification of adenovirus from conjunctival scrapings over a two-year period (between 2001 and 2003) in Yokohama, Japan. J Med Virol: 2007; 79 2 200 205
109. Jin X. H., Ishiko H., Nguyen T. H., et al. Molecular epidemiology of adenoviral conjunctivitis in Hanoi, Vietnam. Am J Ophthalmol: 2006; 142 6 1064 1066
110. Ariga T., Shimada Y., Shiratori K., et al. Five new genome types of adenovirus type 37 caused epidemic keratoconjunctivitis in Sapporo, Japan, for more than 10 years. J Clin Microbiol: 2005; 43 2 726 732
111. Lee Y. C., Chen N., Huang I. T., et al. Human adenovirus type 8 epidemic keratoconjunctivitis with large corneal epithelial full-layer detachment: an endemic outbreak with uncommon manifestations. Clin Ophthalmol: 2015; 9 953 957
112. Centers for Disease Control and Prevention (CDC) Adenovirus-associated epidemic keratoconjunctivitis outbreaks-four states, 2008-2010. MMWR Morb Mortal Wkly Rep: 2013; 62 32 637 641
113. Itakura S., Aoki K., Sawada H., Shinagawa M. Analysis with restriction endonucleases recognizing 4- or 5-base-pair sequences of human adenovirus type 3 isolated from ocular diseases in Sapporo, Japan. J Clin Microbiol: 1990; 28 10 2365 2369
114. Ariga T., Shimada Y., Ohgami K., et al. New genome type of adenovirus serotype 4 caused nosocomial infections associated with epidemic conjunctivitis in Japan. J Clin Microbiol: 2004; 42 8 3644 3648
115. Montessori V., Scharf S., Holland S., Werker D. H., Roberts F. J., Bryce E. Epidemic keratoconjunctivitis outbreak at a tertiary referral eye care clinic. Am J Infect Control: 1998; 26 4 399 405
116. Sendra-Gutiérrez J. M., Martín-Rios D., Casas I., Sáez P., Tovar A., Moreno C. An outbreak of adenovirus type 8 keratoconjunctivitis in a nursing home in Madrid. Euro Surveill: 2004; 9 3 27 30
117. Saitoh-Inagawa W., Aoki K., Uchio E., Itoh N., Ohno S. Ten years' surveillance of viral conjunctivitis in Sapporo, Japan. Graefes Arch Clin Exp Ophthalmol: 1999; 237 1 35 38
118. Kuo I. C., Espinosa C., Forman M., Pehar M., Maragakis L. L., Valsamakis A. Detection and prevalence of adenoviral conjunctivitis among hospital employees using real-time polymerase chain reaction as an infection prevention tool. Infect Control Hosp Epidemiol: 2014; 35 6 728 731
119. Kaneko H., Aoki K., Ishida S., et al. Recombination analysis of intermediate human adenovirus type 53 in Japan by complete genome sequence. J Gen Virol: 2011; 92 Pt 6 1251 1259
120. Huang G., Yao W., Yu W., et al. Outbreak of epidemic keratoconjunctivitis caused by human adenovirus type 56, China, 2012. PLoS ONE: 2014; 9 10 e110781
121. Enomoto M., Okafuji T., Okafuji T., et al. Isolation of an intertypic recombinant human adenovirus (candidate type 56) from the pharyngeal swab of a patient with pharyngoconjunctival fever. Jpn J Infect Dis: 2012; 65 5 457 459
122. Walsh M. P., Chintakuntlawar A., Robinson C. M., et al. Evidence of molecular evolution driven by recombination events influencing tropism in a novel human adenovirus that causes epidemic keratoconjunctivitis. PLoS ONE: 2009; 4 6 e5635
123. Kaneko H., Suzutani T., Aoki K., et al. Epidemiological and virological features of epidemic keratoconjunctivitis due to new human adenovirus type 54 in Japan. Br J Ophthalmol: 2011; 95 1 32 36
124. Hiroi S., Morikawa S., Takahashi K., Komano J., Kase T. Molecular epidemiology of human adenoviruses d associated with epidemic keratoconjunctivitis in Osaka, Japan, 2001-2010. Jpn J Infect Dis: 2013; 66 5 436 438
125. Moyo S. J., Hanevik K., Blomberg B., et al. Prevalence and molecular characterisation of human adenovirus in diarrhoeic children in Tanzania; a case control study. BMC Infect Dis: 2014; 14 666
126. Kapelushnik J., Or R., Delukina M., Nagler A., Livni N., Engelhard D. Intravenous ribavirin therapy for adenovirus gastroenteritis after bone marrow transplantation. J Pediatr Gastroenterol Nutr: 1995; 21 1 110 112
127. Janoff E. N., Orenstein J. M., Manischewitz J. F., Smith P. D. Adenovirus colitis in the acquired immunodeficiency syndrome. Gastroenterology: 1991; 100 4 976 979
128. Wang W. H., Wang H. L. Fulminant adenovirus hepatitis following bone marrow transplantation. A case report and brief review of the literature. Arch Pathol Lab Med: 2003; 127 5 e246 e248
129. Arav-Boger R., Echavarria M., Forman M., Charache P., Persaud D. Clearance of adenoviral hepatitis with ribavirin therapy in a pediatric liver transplant recipient. Pediatr Infect Dis J: 2000; 19 11 1097 1100
130. Putra J., Suriawinata A. A. Adenovirus hepatitis presenting as tumoral lesions in an immunocompromised patient. Ann Hepatol: 2014; 13 6 827 829
131. Yan Z., Nguyen S., Poles M., Melamed J., Scholes J. V. Adenovirus colitis in human immunodeficiency virus infection: an underdiagnosed entity. Am J Surg Pathol: 1998; 22 9 1101 1106
132. Hedderwick S. A., Greenson J. K., McGaughy V. R., Clark N. M. Adenovirus cholecystitis in a patient with AIDS. Clin Infect Dis: 1998; 26 4 997 999
133. Bateman C. M., Kesson A. M., Shaw P. J. Pancreatitis and adenoviral infection in children after blood and marrow transplantation. Bone Marrow Transplant: 2006; 38 12 807 811
134. Kir S., Aydin Y., Kocaman O., et al. Acute pancreatitis after severe opthalmic adenoviral infection. Acta Gastroenterol Belg: 2011; 74 2 361 362
135. Yokose N., Hirakawa T., Inokuchi K. Adenovirus-associated hemorrhagic cystitis in a patient with plasma cell myeloma treated with bortezomib. Leuk Res: 2009; 33 8 e106
136. Akiyama H., Kurosu T., Sakashita C., et al. Adenovirus is a key pathogen in hemorrhagic cystitis associated with bone marrow transplantation. Clin Infect Dis: 2001; 32 9 1325 1330
137. Teramura T., Naya M., Yoshihara T., Kanoh G., Morimoto A., Imashuku S. Adenoviral infection in hematopoietic stem cell transplantation: early diagnosis with quantitative detection of the viral genome in serum and urine. Bone Marrow Transplant: 2004; 33 1 87 92
138. Miyamura K., Hamaguchi M., Taji H., et al. Successful ribavirin therapy for severe adenovirus hemorrhagic cystitis after allogeneic marrow transplant from close HLA donors rather than distant donors. Bone Marrow Transplant: 2000; 25 5 545 548
139. Fanourgiakis P., Georgala A., Vekemans M., et al. Intravesical instillation of cidofovir in the treatment of hemorrhagic cystitis caused by adenovirus type 11 in a bone marrow transplant recipient. Clin Infect Dis: 2005; 40 1 199 201
140. Hofland C. A., Eron L. J., Washecka R. M. Hemorrhagic adenovirus cystitis after renal transplantation. Transplant Proc: 2004; 36 10 3025 3027
141. Ferreira G. F., Oliveira R. A., Lucon M., et al. Hemorrhagic cystitis secondary to adenovirus or herpes simplex virus infection following renal transplantation: four case reports. Transplant Proc: 2009; 41 10 4416 4419
142. Yagisawa T., Nakada T., Takahashi K., Toma H., Ota K., Yaguchi H. Acute hemorrhagic cystitis caused by adenovirus after kidney transplantation. Urol Int: 1995; 54 3 142 146
143. Keswani M., Moudgil A. Adenovirus-associated hemorrhagic cystitis in a pediatric renal transplant recipient. Pediatr Transplant: 2007; 11 5 568 571
144. Koga S., Shindo K., Matsuya F., Hori T., Kanda S., Kanetake H. Acute hemorrhagic cystitis caused by adenovirus following renal transplantation: review of the literature. J Urol: 1993; 149 4 838 839
145. Lachiewicz A. M., Cianciolo R., Miller M. B., Derebail V. K. Adenovirus causing fever, upper respiratory infection, and allograft nephritis complicated by persistent asymptomatic viremia. Transpl Infect Dis: 2014; 16 4 648 652
146. Sujeet K., Vasudev B., Desai P., et al. Acute kidney injury requiring dialysis secondary to adenovirus nephritis in renal transplant recipient. Transpl Infect Dis: 2011; 13 2 174 177
147. Bruno B., Zager R. A., Boeckh M. J., et al. Adenovirus nephritis in hematopoietic stem-cell transplantation. Transplantation: 2004; 77 7 1049 1057
148. Ito M., Hirabayashi N., Uno Y., Nakayama A., Asai J. Necrotizing tubulointerstitial nephritis associated with adenovirus infection. Hum Pathol: 1991; 22 12 1225 1231
149. Ardehali H., Volmar K., Roberts C., Forman M., Becker L. C. Fatal disseminated adenoviral infection in a renal transplant patient. Transplantation: 2001; 71 7 998 999
150. Echavarria M., Forman M., van Tol M. J., Vossen J. M., Charache P., Kroes A. C. Prediction of severe disseminated adenovirus infection by serum PCR. Lancet: 2001; 358 9279 384 385
151. Mori K., Yoshihara T., Nishimura Y., et al. Acute renal failure due to adenovirus-associated obstructive uropathy and necrotizing tubulointerstitial nephritis in a bone marrow transplant recipient. Bone Marrow Transplant: 2003; 31 12 1173 1176
152. Liddle O. L., Samuel M. I., Sudhanva M., Ellis J., Taylor C. Adenovirus urethritis and concurrent conjunctivitis: a case series and review of the literature. Sex Transm Infect: 2015; 91 2 87 90
153. Sivaprakasam P., Carr T. F., Coussons M., et al. Improved outcome from invasive adenovirus infection in pediatric patients after hemopoietic stem cell transplantation using intensive clinical surveillance and early intervention. J Pediatr Hematol Oncol: 2007; 29 2 81 85
154. Robin M., Marque-Juillet S., Scieux C., et al. Disseminated adenovirus infections after allogeneic hematopoietic stem cell transplantation: incidence, risk factors and outcome. Haematologica: 2007; 92 9 1254 1257
155. Kroes A. C., de Klerk E. P., Lankester A. C., et al. Sequential emergence of multiple adenovirus serotypes after pediatric stem cell transplantation. J Clin Virol: 2007; 38 4 341 347
156. de Mezerville M. H., Tellier R., Richardson S., Hébert D., Doyle J., Allen U. Adenoviral infections in pediatric transplant recipients: a hospital-based study. Pediatr Infect Dis J: 2006; 25 9 815 818
157. Venard V., Carret A., Corsaro D., Bordigoni P., Le Faou A. Genotyping of adenoviruses isolated in an outbreak in a bone marrow transplant unit shows that diverse strains are involved. J Hosp Infect: 2000; 44 1 71 74
158. Hoffman J. A., Shah A. J., Ross L. A., Kapoor N. Adenoviral infections and a prospective trial of cidofovir in pediatric hematopoietic stem cell transplantation. Biol Blood Marrow Transplant: 2001; 7 7 388 394
159. Kelsey D. S. Adenovirus meningoencephalitis. Pediatrics: 1978; 61 2 291 293
160. Ladisch S., Lovejoy F. H., Hierholzer J. C., et al. Extrapulmonary manifestations of adenovirus type 7 pneumonia simulating Reye syndrome and the possible role of an adenovirus toxin. J Pediatr: 1979; 95 3 348 355
161. Gray G. C., McCarthy T., Lebeck M. G., et al. Genotype prevalence and risk factors for severe clinical adenovirus infection, United States 2004-2006. Clin Infect Dis: 2007; 45 9 1120 1131
162. Huang Y. C., Huang S. L., Chen S. P., et al. Adenovirus infection associated with central nervous system dysfunction in children. J Clin Virol: 2013; 57 4 300 304
163. Dubberke E. R., Tu B., Rivet D. J., et al. Acute meningoencephalitis caused by adenovirus serotype 26. J Neurovirol: 2006; 12 3 235 240
164. Reyes-Andrade J., Sánchez-Céspedes J., Olbrich P., et al. Meningoencephalitis due to adenovirus in a healthy infant mimicking severe bacterial sepsis. Pediatr Infect Dis J: 2014; 33 4 416 419
165. Frange P., Peffault de Latour R., Arnaud C., et al. Adenoviral infection presenting as an isolated central nervous system disease without detectable viremia in two children after stem cell transplantation. J Clin Microbiol: 2011; 49 6 2361 2364
166. Bowles N. E., Ni J., Kearney D. L., et al. Detection of viruses in myocardial tissues by polymerase chain reaction. evidence of adenovirus as a common cause of myocarditis in children and adults. J Am Coll Cardiol: 2003; 42 3 466 472
167. Valdés O., Acosta B., Piñón A., et al. First report on fatal myocarditis associated with adenovirus infection in Cuba. J Med Virol: 2008; 80 10 1756 1761
168. Melón S., Méndez S., Iglesias B., et al. Involvement of adenovirus in clinical mononucleosis-like syndromes in young children. Eur J Clin Microbiol Infect Dis: 2005; 24 5 314 318
169. Couroucli X. I., Welty S. E., Ramsay P. L., et al. Detection of microorganisms in the tracheal aspirates of preterm infants by polymerase chain reaction: association of adenovirus infection with bronchopulmonary dysplasia. Pediatr Res: 2000; 47 2 225 232
170. Guarner J., de Leon-Bojorge B., Lopez-Corella E., et al. Intestinal intussusception associated with adenovirus infection in Mexican children. Am J Clin Pathol: 2003; 120 6 845 850
171. Bajanowski T., Wiegand P., Cecchi R., et al. Detection and significance of adenoviruses in cases of sudden infant death. Virchows Arch: 1996; 428 2 113 118
172. Rodríguez-Martínez C. E., Rodríguez D. A., Nino G. Respiratory syncytial virus, adenoviruses, and mixed acute lower respiratory infections in children in a developing country. J Med Virol: 2015; 87 5 774 781
173. Russell K. L., Baker C. I., Hansen C., et al. Lack of effectiveness of the 23-valent polysaccharide pneumococcal vaccine in reducing all-cause pneumonias among healthy young military recruits: a randomized, double-blind, placebo-controlled trial. Vaccine: 2015; 33 9 1182 1187
174. Top F. H. Jr. Control of adenovirus acute respiratory disease in U.S. Army trainees. Yale J Biol Med: 1975; 48 3 185 195
175. Radin J. M., Hawksworth A. W., Blair P. J., et al. Dramatic decline of respiratory illness among US military recruits after the renewed use of adenovirus vaccines. Clin Infect Dis: 2014; 59 7 962 968
176. Barraza E. M., Ludwig S. L., Gaydos J. C., Brundage J. F. Reemergence of adenovirus type 4 acute respiratory disease in military trainees: report of an outbreak during a lapse in vaccination. J Infect Dis: 1999; 179 6 1531 1533
177. Hendrix R. M., Lindner J. L., Benton F. R., et al. Large, persistent epidemic of adenovirus type 4-associated acute respiratory disease in U.S. army trainees. Emerg Infect Dis: 1999; 5 6 798 801
178. Gray G. C., Goswami P. R., Malasig M. D., et al. For the Adenovirus Surveillance Group. Adult adenovirus infections: loss of orphaned vaccines precipitates military respiratory disease epidemics. Clin Infect Dis: 2000; 31 3 663 670
179. Kuschner R. A., Russell K. L., Abuja M., et al. Adenovirus Vaccine Efficacy Trial Consortium. A phase 3, randomized, double-blind, placebo-controlled study of the safety and efficacy of the live, oral adenovirus type 4 and type 7 vaccine, in U.S. military recruits. Vaccine: 2013; 31 28 2963 2971
180. Leen A. M., Rooney C. M. Adenovirus as an emerging pathogen in immunocompromised patients. Br J Haematol: 2005; 128 2 135 144
181. Baldwin A., Kingman H., Darville M., et al. Outcome and clinical course of 100 patients with adenovirus infection following bone marrow transplantation. Bone Marrow Transplant: 2000; 26 12 1333 1338
182. La Rosa A. M., Champlin R. E., Mirza N., et al. Adenovirus infections in adult recipients of blood and marrow transplants. Clin Infect Dis: 2001; 32 6 871 876
183. George D., El-Mallawany N. K., Jin Z., et al. Adenovirus infection in paediatric allogeneic stem cell transplantation recipients is a major independent factor for significantly increasing the risk of treatment related mortality. Br J Haematol: 2012; 156 1 99 108
184. Fowler C. J., Dunlap J., Troyer D., Stenzel P., Epner E., Maziarz R. T. Life-threatening adenovirus infections in the setting of the immunocompromised allogeneic stem cell transplant patients. Adv Hematol: 2010; 2010 601548
185. Abinun M., Flood T. J., Cant A. J., et al. Autologous T cell depleted haematopoietic stem cell transplantation in children with severe juvenile idiopathic arthritis in the UK (2000-2007). Mol Immunol: 2009; 47 1 46 51
186. Kohno K., Nagafuji K., Tsukamoto H., et al. Infectious complications in patients receiving autologous CD34-selected hematopoietic stem cell transplantation for severe autoimmune diseases. Transpl Infect Dis: 2009; 11 4 318 323
187. Mori Y., Miyamoto T., Kamezaki K., et al. Low incidence of adenovirus hemorrhagic cystitis following autologous hematopoietic stem cell transplantation in the rituximab era. Am J Hematol: 2012; 87 8 828 830
188. Yusuf U., Hale G. A., Carr J., et al. Cidofovir for the treatment of adenoviral infection in pediatric hematopoietic stem cell transplant patients. Transplantation: 2006; 81 10 1398 1404
189. Leruez-Ville M., Minard V., Lacaille F., et al. Real-time blood plasma polymerase chain reaction for management of disseminated adenovirus infection. Clin Infect Dis: 2004; 38 1 45 52
190. Runde V., Ross S., Trenschel R., et al. Adenoviral infection after allogeneic stem cell transplantation (SCT): report on 130 patients from a single SCT unit involved in a prospective multi center surveillance study. Bone Marrow Transplant: 2001; 28 1 51 57
191. Lee Y. J., Chung D., Xiao K., et al. Adenovirus viremia and disease: comparison of T cell-depleted and conventional hematopoietic stem cell transplantation recipients from a single institution. Biol Blood Marrow Transplant: 2013; 19 3 387 392
192. Muller W. J., Levin M. J., Shin Y. K., et al. Clinical and in vitro evaluation of cidofovir for treatment of adenovirus infection in pediatric hematopoietic stem cell transplant recipients. Clin Infect Dis: 2005; 41 12 1812 1816
193. Sive J. I., Thomson K. J., Morris E. C., Ward K. N., Peggs K. S. Adenoviremia has limited clinical impact in the majority of patients following alemtuzumab-based allogeneic stem cell transplantation in adults. Clin Infect Dis: 2012; 55 10 1362 1370
194. Lankester A. C., van Tol M. J., Claas E. C., Vossen J. M., Kroes A. C. Quantification of adenovirus DNA in plasma for management of infection in stem cell graft recipients. Clin Infect Dis: 2002; 34 6 864 867
195. Schilham M. W., Claas E. C., van Zaane W., et al. High levels of adenovirus DNA in serum correlate with fatal outcome of adenovirus infection in children after allogeneic stem-cell transplantation. Clin Infect Dis: 2002; 35 5 526 532
196. Humar A., Kumar D., Mazzulli T., et al. PV16000 Study Group. A surveillance study of adenovirus infection in adult solid organ transplant recipients. Am J Transplant: 2005; 5 10 2555 2559
197. Hierholzer J. C. Adenoviruses in the immunocompromised host. Clin Microbiol Rev: 1992; 5 3 262 274
198. Michaels M. G., Green M., Wald E. R., Starzl T. E. Adenovirus infection in pediatric liver transplant recipients. J Infect Dis: 1992; 165 1 170 174
199. McGrath D., Falagas M. E., Freeman R., et al. Adenovirus infection in adult orthotopic liver transplant recipients: incidence and clinical significance. J Infect Dis: 1998; 177 2 459 462
200. Bridges N. D., Spray T. L., Collins M. H., Bowles N. E., Towbin J. A. Adenovirus infection in the lung results in graft failure after lung transplantation. J Thorac Cardiovasc Surg: 1998; 116 4 617 623
201. Florescu M. C., Miles C. D., Florescu D. F. What do we know about adenovirus in renal transplantation? Nephrol Dial Transplant: 2013; 28 8 2003 2010
202. Watcharananan S. P., Avery R., Ingsathit A., et al. Adenovirus disease after kidney transplantation: course of infection and outcome in relation to blood viral load and immune recovery. Am J Transplant: 2011; 11 6 1308 1314
203. Florescu D. F., Kwon J. Y., Dumitru I. Adenovirus infections in heart transplantation. Cardiol Rev: 2013; 21 4 203 206
204. Bruminhent J., Athas D. M., Hess B. D., Flomenberg P. Disseminated adenovirus disease in heart transplant recipient presenting with conjunctivitis. Transpl Infect Dis: 2015; 17 1 125 128
205. McLaughlin G. E., Delis S., Kashimawo L., et al. Adenovirus infection in pediatric liver and intestinal transplant recipients: utility of DNA detection by PCR. Am J Transplant: 2003; 3 2 224 228
206. Florescu D. F., Islam M. K., Mercer D. F., et al. Adenovirus infections in pediatric small bowel transplant recipients. Transplantation: 2010; 90 2 198 204
207. Ohori N. P., Michaels M. G., Jaffe R., Williams P., Yousem S. A. Adenovirus pneumonia in lung transplant recipients. Hum Pathol: 1995; 26 10 1073 1079
208. Humar A., Doucette K., Kumar D., et al. Assessment of adenovirus infection in adult lung transplant recipients using molecular surveillance. J Heart Lung Transplant: 2006; 25 12 1441 1446
209. Doan M. L., Mallory G. B., Kaplan S. L., et al. Treatment of adenovirus pneumonia with cidofovir in pediatric lung transplant recipients. J Heart Lung Transplant: 2007; 26 9 883 889
210. Florescu D. F., Hoffman J. A.; AST Infectious Diseases Community of Practice. Adenovirus in solid organ transplantation. Am J Transplant: 2013; 13 4 04 206 211
211. Moulik M., Breinholt J. P., Dreyer W. J., et al. Viral endomyocardial infection is an independent predictor and potentially treatable risk factor for graft loss and coronary vasculopathy in pediatric cardiac transplant recipients. J Am Coll Cardiol: 2010; 56 7 582 592
212. Shirali G. S., Ni J., Chinnock R. E., et al. Association of viral genome with graft loss in children after cardiac transplantation. N Engl J Med: 2001; 344 20 1498 1503
213. Schowengerdt K. O., Ni J., Denfield S. W., et al. Diagnosis, surveillance, and epidemiologic evaluation of viral infections in pediatric cardiac transplant recipients with the use of the polymerase chain reaction. J Heart Lung Transplant: 1996; 15 2 111 123
214. Simsir A., Greenebaum E., Nuovo G., Schulman L. L. Late fatal adenovirus pneumonitis in a lung transplant recipient. Transplantation: 1998; 65 4 592 594
215. Ferdman R. M., Ross L., Inderlied C., Church J. A. Adenovirus viremia in human immunodeficiency virus-infected children. Pediatr Infect Dis J: 1997; 16 4 413 415
216. Khoo S. H., Bailey A. S., de Jong J. C., Mandal B. K. Adenovirus infections in human immunodeficiency virus-positive patients: clinical features and molecular epidemiology. J Infect Dis: 1995; 172 3 629 637
217. Kolawole O. M., Oladosu T. O., Abdulkarim A. A., Okoh A. I. Prevalence of adenovirus respiratory tract and hiv co-infections in patients attending the University of Ilorin, teaching hospital, Ilorin, Nigeria. BMC Res Notes: 2014; 7 870
218. de Jong P. J., Valderrama G., Spigland I., Horwitz M. S. Adenovirus isolates from urine of patients with acquired immunodeficiency syndrome. Lancet: 1983; 1 8337 1293 1296
219. Winkelstein J. A., Marino M. C., Lederman H. M., et al. X-linked agammaglobulinemia: report on a United States registry of 201 patients. Medicine (Baltimore): 2006; 85 4 193 202
220. Baum S. Adenovirus. In: Mandell G. L., Bennett J. E., Dolin R., eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 6th ed. Philadelphia, PA Elsevier Churchill Livingstone: 2005; 1835 1841
221. Centers for Disease Control and Prevention (CDC) Acute respiratory disease associated with adenovirus serotype 14-four states, 2006-2007. MMWR Morb Mortal Wkly Rep: 2007; 56 45 1181 1184
222. Esposito D. H., Gardner T. J., Schneider E., et al. Outbreak of pneumonia associated with emergent human adenovirus serotype 14-Southeast Alaska, 2008. J Infect Dis: 2010; 202 2 214 222
223. Chmielewicz B., Benzler J., Pauli G., Krause G., Bergmann F., Schweiger B. Respiratory disease caused by a species B2 adenovirus in a military camp in Turkey. J Med Virol: 2005; 77 2 232 237
224. Kajon A. E., Mistchenko A. S., Videla C., Hortal M., Wadell G., Avendaño L. F. Molecular epidemiology of adenovirus acute lower respiratory infections of children in the south cone of South America (1991-1994). J Med Virol: 1996; 48 2 151 156
225. Ison M. G., Green M.; AST Infectious Diseases Community of Practice. Adenovirus in solid organ transplant recipients. Am J Transplant: 2009; 9 4 04 S161 S165
226. Elnifro E. M., Cooper R. J., Klapper P. E., Bailey A. S., Tullo A. B. Diagnosis of viral and chlamydial keratoconjunctivitis: which laboratory test? Br J Ophthalmol: 1999; 83 5 622 627
227. Uhnoo I., Wadell G., Svensson L., Johansson M. E. Importance of enteric adenoviruses 40 and 41 in acute gastroenteritis in infants and young children. J Clin Microbiol: 1984; 20 3 365 372
228. Wold W., Horwitz M. Adenoviruses. In: Knipe D. M., Howley P. M., eds. Fields Virology. 5th ed. Philadelphia, PA Lippincott, Williams & Wilkins, Inc.: 2007; 2395 2436
229. Suparno C., Milligan D. W., Moss P. A., Mautner V. Adenovirus infections in stem cell transplant recipients: recent developments in understanding of pathogenesis, diagnosis and management. Leuk Lymphoma: 2004; 45 5 873 885
230. van Kraaij M. G., van Elden L. J., van Loon A. M., et al. Frequent detection of respiratory viruses in adult recipients of stem cell transplants with the use of real-time polymerase chain reaction, compared with viral culture. Clin Infect Dis: 2005; 40 5 662 669
231. Wallot M. A., Dohna-Schwake C., Auth M., et al. Disseminated adenovirus infection with respiratory failure in pediatric liver transplant recipients: impact of intravenous cidofovir and inhaled nitric oxide. Pediatr Transplant: 2006; 10 1 121 127
232. Landry M. L., Lebeck M. G., Capuano A. W., McCarthy T., Gray G. C. Adenovirus type 3 outbreak in connecticut associated with a novel variant. J Med Virol: 2009; 81 8 1380 1384
233. Adhikary A. K., Inada T., Banik U., Numaga J., Okabe N. Identification of subgenus C adenoviruses by fiber-based multiplex PCR. J Clin Microbiol: 2004; 42 2 670 673
234. Kajon A. E., Erdman D. D. Assessment of genetic variability among subspecies b1 human adenoviruses for molecular epidemiology studies. Methods Mol Med: 2007; 131 335 355
235. Xu W., Erdman D. D. Type-specific identification of human adenovirus 3, 7, and 21 by a multiplex PCR assay. J Med Virol: 2001; 64 4 537 542
236. Li Q. G., Wadell G. Analysis of 15 different genome types of adenovirus type 7 isolated on five continents. J Virol: 1986; 60 1 331 335
237. Robinson C. M., Zhou X., Rajaiya J., et al. Predicting the next eye pathogen: analysis of a novel adenovirus. MBio: 2013; 4 2 e00595 e12
238. Robinson C. M., Seto D., Jones M. S., Dyer D. W., Chodosh J. Molecular evolution of human species D adenoviruses. Infect Genet Evol: 2011; 11 6 1208 1217
239. Robinson C. M., Singh G., Henquell C., et al. Computational analysis and identification of an emergent human adenovirus pathogen implicated in a respiratory fatality. Virology: 2011; 409 2 141 147
240. Zhang Q., Seto D., Cao B., Zhao S., Wan C. Genome sequence of human adenovirus type 55, a re-emergent acute respiratory disease pathogen in China. J Virol: 2012; 86 22 12441 12442
241. Seto D., Chodosh J., Brister J. R., Jones M. S.; Members of the Adenovirus Research Community. Using the whole-genome sequence to characterize and name human adenoviruses. J Virol: 2011; 85 11 5701 5702
242. Yamadera S., Yamashita K., Akatsuka M., Kato N., Inouye S. Trend of adenovirus type 7 infection, an emerging disease in Japan. A report of the National Epidemiological Surveillance of Infectious Agents in Japan. Jpn J Med Sci Biol: 1998; 51 1 43 51
243. Azar R., Varsano N., Mileguir F., Mendelson E. Molecular epidemiology of adenovirus type 7 in Israel: identification of two new genome types, Ad7k and Ad7d2. J Med Virol: 1998; 54 4 291 299
244. Wadell G., Cooney M. K., da Costa Linhares A., et al. Molecular epidemiology of adenoviruses: global distribution of adenovirus 7 genome types. J Clin Microbiol: 1985; 21 3 403 408
245. Metzgar D., Osuna M., Yingst S., et al. PCR analysis of egyptian respiratory adenovirus isolates, including identification of species, serotypes, and coinfections. J Clin Microbiol: 2005; 43 11 5743 5752
246. Kajon A. E., Wadell G. Molecular epidemiology of adenoviruses associated with acute lower respiratory disease of children in Buenos Aires, Argentina (1984-1988). J Med Virol: 1992; 36 4 292 297
247. Piedra P. A., Poveda G. A., Ramsey B., McCoy K., Hiatt P. W. Incidence and prevalence of neutralizing antibodies to the common adenoviruses in children with cystic fibrosis: implication for gene therapy with adenovirus vectors. Pediatrics: 1998; 101 6 1013 1019
248. Cooper R. J., Hallett R., Tullo A. B., Klapper P. E. The epidemiology of adenovirus infections in Greater Manchester, UK 1982-96. Epidemiol Infect: 2000; 125 2 333 345
249. Kim Y. J., Hong J. Y., Lee H. J., et al. Genome type analysis of adenovirus types 3 and 7 isolated during successive outbreaks of lower respiratory tract infections in children. J Clin Microbiol: 2003; 41 10 4594 4599
250. Murtagh P., Cerqueiro C., Halac A., Avila M., Kajon A. Adenovirus type 7h respiratory infections: a report of 29 cases of acute lower respiratory disease. Acta Paediatr: 1993; 82 6-7 557 561
251. Li Q. G., Wadell G. Comparison of 17 genome types of adenovirus type 3 identified among strains recovered from six continents. J Clin Microbiol: 1988; 26 5 1009 1015
252. Adrian T., Best B., Hierholzer J. C., Wigand R. Molecular epidemiology and restriction site mapping of adenovirus type 3 genome types. J Clin Microbiol: 1989; 27 6 1329 1334
253. Cassir N., Hraiech S., Nougairede A., Zandotti C., Fournier P. E., Papazian L. Outbreak of adenovirus type 1 severe pneumonia in a French intensive care unit, September-October 2012. Euro Surveill: 2014; 19 39 20914
254. Rebelo-de-Andrade H., Pereira C., Gíria M., et al. Outbreak of acute respiratory infection among infants in Lisbon, Portugal, caused by human adenovirus serotype 3 and a new 7/3 recombinant strain. J Clin Microbiol: 2010; 48 4 1391 1396
255. Kandel R., Srinivasan A., D'Agata E. M., Lu X., Erdman D., Jhung M. Outbreak of adenovirus type 4 infection in a long-term care facility for the elderly. Infect Control Hosp Epidemiol: 2010; 31 7 755 757
256. Top F. H. Jr, Buescher E. L., Bancroft W. H., Russell P. K. Immunization with live types 7 and 4 adenovirus vaccines. II. Antibody response and protective effect against acute respiratory disease due to adenovirus type 7. J Infect Dis: 1971; 124 2 155 160
257. Top F. H. Jr, Grossman R. A., Bartelloni P. J., et al. Immunization with live types 7 and 4 adenovirus vaccines. I. Safety, infectivity, antigenicity, and potency of adenovirus type 7 vaccine in humans. J Infect Dis: 1971; 124 2 148 154
258. Choi E. H., Kim H. S., Eun B. W., et al. Adenovirus type 7 peptide diversity during outbreak, Korea, 1995-2000. Emerg Infect Dis: 2005; 11 5 649 654
259. Noda M., Yoshida T., Sakaguchi T., Ikeda Y., Yamaoka K., Ogino T. Molecular and epidemiological analyses of human adenovirus type 7 strains isolated from the 1995 nationwide outbreak in Japan. J Clin Microbiol: 2002; 40 1 140 145
260. Cho C. T., Hiatt W. O., Behbehani A. M. Pneumonia and massive pleural effusion associated with adenovirus type 7. Am J Dis Child: 1973; 126 1 92 94
261. Yamamoto D., Okamoto M., Lupisan S., et al. Impact of human adenovirus serotype 7 in hospitalized children with severe fatal pneumonia in the Philippines. Jpn J Infect Dis: 2014; 67 2 105 110
262. Zhao S., Wan C., Ke C., et al. Re-emergent human adenovirus genome type 7d caused an acute respiratory disease outbreak in Southern China after a twenty-one year absence. Sci Rep: 2014; 4 7365
263. Brown R. S., Nogrady M. B., Spence L., Wiglesworth F. W. An outbreak of adenovirus type 7 infection in children in Montreal. Can Med Assoc J: 1973; 108 4 434 439
264. Wadell G., Varsányi T. M., Lord A., Sutton R. N. Epidemic outbreaks of adenovirus 7 with special reference to the pathogenicity of adenovirus genome type 7b. Am J Epidemiol: 1980; 112 5 619 628
265. Cui X., Wen L., Wu Z., et al. Human adenovirus type 7 infection associated with severe and fatal acute lower respiratory illness and nosocomial transmission. J Clin Microbiol: 2015; 53 2 746 749
266. Centers for Disease Control (CDC) Adenovirus type 7 outbreak in a pediatric chronic-care facility-Pennsylvania, 1982. MMWR Morb Mortal Wkly Rep: 1983; 32 19 258 260
267. Kajon A., Wadell G. Genome analysis of South American adenovirus strains of serotype 7 collected over a 7-year period. J Clin Microbiol: 1994; 32 9 2321 2323
268. de Silva L. M., Colditz P., Wadell G. Adenovirus type 7 infections in children in New South Wales, Australia. J Med Virol: 1989; 29 1 28 32
269. Straube R. C., Thompson M. A., Van Dyke R. B., et al. Adenovirus type 7b in a children's hospital. J Infect Dis: 1983; 147 5 814 819
270. Sakata H., Taketazu G., Nagaya K., et al. Outbreak of severe infection due to adenovirus type 7 in a paediatric ward in Japan. J Hosp Infect: 1998; 39 3 207 211
271. Tang L., Wang L., Tan X., Xu W. Adenovirus serotype 7 associated with a severe lower respiratory tract disease outbreak in infants in Shaanxi Province, China. Virol J: 2011; 8 23
272. Ersoy Y., Otlu B., Türkçüoǧlu P., Yetkin F., Aker S., Kuzucu C. Outbreak of adenovirus serotype 8 conjunctivitis in preterm infants in a neonatal intensive care unit. J Hosp Infect: 2012; 80 2 144 149
273. Adhikary A. K., Banik U. Human adenovirus type 8: the major agent of epidemic keratoconjunctivitis (EKC). J Clin Virol: 2014; 61 4 477 486
274. Metzgar D., Osuna M., Kajon A. E., Hawksworth A. W., Irvine M., Russell K. L. Abrupt emergence of diverse species B adenoviruses at US military recruit training centers. J Infect Dis: 2007; 196 10 1465 1473
275. Asim M., Chong-Lopez A., Nickeleit V. Adenovirus infection of a renal allograft. Am J Kidney Dis: 2003; 41 3 696 701
276. Kendall E. J., Riddle R. W., Tuck H. A., Rodan K. S., Andrews B. E., McDonald J. C. Pharyngo-conjunctival fever; school outbreaks in England during the summer of 1955 associated with adenovirus types 3, 7, and 14. BMJ: 1957; 2 5037 131 136
277. Tate J. E., Bunning M. L., Lott L., et al. Outbreak of severe respiratory disease associated with emergent human adenovirus serotype 14 at a US air force training facility in 2007. J Infect Dis: 2009; 199 10 1419 1426
278. Lewis P. F., Schmidt M. A., Lu X., et al. A community-based outbreak of severe respiratory illness caused by human adenovirus serotype 14. J Infect Dis: 2009; 199 10 1427 1434
279. O'Flanagan D., O'Donnell J., Domegan L., et al. First reported cases of human adenovirus serotype 14p1 infection, Ireland, October 2009 to July 2010. Euro Surveill: 2011; 16 8 1 5
280. Van Der Veen J., Dijkman J. H. Association of type 21 adenovirus with acute respiratory illness in military recruits. Am J Hyg: 1962; 76 149 159
281. van der Avoort H. G., Adrian T., Wigand R., Wermenbol A. G., Zomerdijk T. P., de Jong J. C. Molecular epidemiology of adenovirus type 21 in the Netherlands and the Federal Republic of Germany from 1960 to 1985. J Clin Microbiol: 1986; 24 6 1084 1088
282. Larsen R. A., Jacobson J. T., Jacobson J. A., Strikas R. A., Hierholzer J. C. Hospital-associated epidemic of pharyngitis and conjunctivitis caused by adenovirus (21/H21 + 35). J Infect Dis: 1986; 154 4 706 709
283. Shult P. A., Polyak F., Dick E. C., Warshauer D. M., King L. A., Mandel A. D. Adenovirus 21 infection in an isolated antarctic station: transmission of the virus and susceptibility of the population. Am J Epidemiol: 1991; 133 6 599 607
284. Ooi M. H., Wong S. C., Clear D., et al. Adenovirus type 21-associated acute flaccid paralysis during an outbreak of hand-foot-and-mouth disease in Sarawak, Malaysia. Clin Infect Dis: 2003; 36 5 550 559
285. Cardosa M. J., Krishnan S., Tio P. H., Perera D., Wong S. C. Isolation of subgenus B adenovirus during a fatal outbreak of enterovirus 71-associated hand, foot, and mouth disease in Sibu, Sarawak. Lancet: 1999; 354 9183 987 991
286. Seidemann K., Heim A., Pfister E. D., et al. Monitoring of adenovirus infection in pediatric transplant recipients by quantitative PCR: report of six cases and review of the literature. Am J Transplant: 2004; 4 12 2102 2108
287. Kampmann B., Cubitt D., Walls T., et al. Improved outcome for children with disseminated adenoviral infection following allogeneic stem cell transplantation. Br J Haematol: 2005; 130 4 595 603
288. Leruez-Ville M., Chardin-Ouachée M., Neven B., et al. Description of an adenovirus A31 outbreak in a paediatric haematology unit. Bone Marrow Transplant: 2006; 38 1 23 28
289. Slatter M. A., Read S., Taylor C. E., et al. Adenovirus type F subtype 41 causing disseminated disease following bone marrow transplantation for immunodeficiency. J Clin Microbiol: 2005; 43 3 1462 1464
290. Li X., Kong M., Su X., et al. An outbreak of acute respiratory disease in China caused by human adenovirus type B55 in a physical training facility. Int J Infect Dis: 2014; 28 117 122
291. Sun B., He H., Wang Z., et al. Emergent severe acute respiratory distress syndrome caused by adenovirus type 55 in immunocompetent adults in 2013: a prospective observational study. Crit Care: 2014; 18 4 456
292. Kajon A. E., de Jong J. C., Dickson L. M., et al. Molecular and serological characterization of species B2 adenovirus strains isolated from children hospitalized with acute respiratory disease in Buenos Aires, Argentina. J Clin Virol: 2013; 58 1 4 10
293. Hierholzer J. C., Pumarola A. Antigenic characterization of intermediate adenovirus 14-11 strains associated with upper respiratory illness in a military camp. Infect Immun: 1976; 13 2 354 359
294. Li Q. G., Hambraeus J., Wadell G. Genetic relationship between thirteen genome types of adenovirus 11, 34, and 35 with different tropisms. Intervirology: 1991; 32 6 338 350
295. Erard V., Huang M. L., Ferrenberg J., et al. Quantitative real-time polymerase chain reaction for detection of adenovirus after T cell-replete hematopoietic cell transplantation: viral load as a marker for invasive disease. Clin Infect Dis: 2007; 45 8 958 965
296. Lankester A. C., Heemskerk B., Claas E. C., et al. Effect of ribavirin on the plasma viral DNA load in patients with disseminating adenovirus infection. Clin Infect Dis: 2004; 38 11 1521 1525
297. Lion T., Kosulin K., Landlinger C., et al. Monitoring of adenovirus load in stool by real-time PCR permits early detection of impending invasive infection in patients after allogeneic stem cell transplantation. Leukemia: 2010; 24 4 706 714
298. Sarantis H., Johnson G., Brown M., Petric M., Tellier R. Comprehensive detection and serotyping of human adenoviruses by PCR and sequencing. J Clin Microbiol: 2004; 42 9 3963 3969
299. Kajon A. E., Dickson L. M., Murtagh P., Viale D., Carballal G., Echavarria M. Molecular characterization of an adenovirus 3-16 intertypic recombinant isolated in Argentina from an infant hospitalized with acute respiratory infection. J Clin Microbiol: 2010; 48 4 1494 1496
300. Kajon A. E., Lamson D., Shudt M., et al. Identification of a novel intertypic recombinant species D human adenovirus in a pediatric stem cell transplant recipient. J Clin Virol: 2014; 61 4 496 502
301. Naesens L., Lenaerts L., Andrei G., et al. Antiadenovirus activities of several classes of nucleoside and nucleotide analogues. Antimicrob Agents Chemother: 2005; 49 3 1010 1016
302. Morfin F., Dupuis-Girod S., Mundweiler S., et al. In vitro susceptibility of adenovirus to antiviral drugs is species-dependent. Antivir Ther: 2005; 10 2 225 229
303. Gavin P. J., Katz B. Z. Intravenous ribavirin treatment for severe adenovirus disease in immunocompromised children. Pediatrics: 2002; 110 1 Pt 1 e9
304. Bhadri V. A., Lee-Horn L., Shaw P. J. Safety and tolerability of cidofovir in high-risk pediatric patients. Transpl Infect Dis: 2009; 11 4 373 379
305. Hartline C. B., Gustin K. M., Wan W. B., et al. Ether lipid-ester prodrugs of acyclic nucleoside phosphonates: activity against adenovirus replication in vitro. J Infect Dis: 2005; 191 3 396 399
306. Toth K., Spencer J. F., Dhar D., et al. Hexadecyloxypropyl-cidofovir, CMX001, prevents adenovirus-induced mortality in a permissive, immunosuppressed animal model. Proc Natl Acad Sci U S A: 2008; 105 20 7293 7297
307. Tollefson A. E., Spencer J. F., Ying B., Buller R. M., Wold W. S., Toth K. Cidofovir and brincidofovir reduce the pathology caused by systemic infection with human type 5 adenovirus in immunosuppressed Syrian hamsters, while ribavirin is largely ineffective in this model. Antiviral Res: 2014; 112 38 46
308. Florescu D. F., Pergam S. A., Neely M. N., et al. Safety and efficacy of CMX001 as salvage therapy for severe adenovirus infections in immunocompromised patients. Biol Blood Marrow Transplant: 2012; 18 5 731 738
309. Paolino K., Sande J., Perez E., et al. Eradication of disseminated adenovirus infection in a pediatric hematopoietic stem cell transplantation recipient using the novel antiviral agent CMX001. J Clin Virol: 2011; 50 2 167 170
310. Marty F. M., Winston D. J., Rowley S. D., et al. CMX001-201 Clinical Study Group. CMX001 to prevent cytomegalovirus disease in hematopoietic-cell transplantation. N Engl J Med: 2013; 369 13 1227 1236
311. Ljungman P., Ribaud P., Eyrich M., et al. Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation. Cidofovir for adenovirus infections after allogeneic hematopoietic stem cell transplantation: a survey by the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant: 2003; 31 6 481 486
312. Legrand F., Berrebi D., Houhou N., et al. Early diagnosis of adenovirus infection and treatment with cidofovir after bone marrow transplantation in children. Bone Marrow Transplant: 2001; 27 6 621 626
313. Mynarek M., Ganzenmueller T., Mueller-Heine A., et al. Patient, virus, and treatment-related risk factors in pediatric adenovirus infection after stem cell transplantation: results of a routine monitoring program. Biol Blood Marrow Transplant: 2014; 20 2 250 256
314. Engelmann G., Heim A., Greil J., et al. Adenovirus infection and treatment with cidofovir in children after liver transplantation. Pediatr Transplant: 2009; 13 4 421 428
315. Refaat M., McNamara D., Teuteberg J., et al. Successful cidofovir treatment in an adult heart transplant recipient with severe adenovirus pneumonia. J Heart Lung Transplant: 2008; 27 6 699 700
316. Saquib R., Melton L. B., Chandrakantan A., et al. Disseminated adenovirus infection in renal transplant recipients: the role of cidofovir and intravenous immunoglobulin. Transpl Infect Dis: 2010; 12 1 77 83
317. Anderson E. J., Guzman-Cottrill J. A., Kletzel M., et al. High-risk adenovirus-infected pediatric allogeneic hematopoietic progenitor cell transplant recipients and preemptive cidofovir therapy. Pediatr Transplant: 2008; 12 2 219 227
318. Nagafuji K., Aoki K., Henzan H., et al. Cidofovir for treating adenoviral hemorrhagic cystitis in hematopoietic stem cell transplant recipients. Bone Marrow Transplant: 2004; 34 10 909 914
319. Chakrabarti S., Mautner V., Osman H., et al. Adenovirus infections following allogeneic stem cell transplantation: incidence and outcome in relation to graft manipulation, immunosuppression, and immune recovery. Blood: 2002; 100 5 1619 1627
320. Heemskerk B., Lankester A. C., van Vreeswijk T., et al. Immune reconstitution and clearance of human adenovirus viremia in pediatric stem-cell recipients. J Infect Dis: 2005; 191 4 520 530
321. van Tol M. J., Claas E. C., Heemskerk B., et al. Adenovirus infection in children after allogeneic stem cell transplantation: diagnosis, treatment and immunity. Bone Marrow Transplant: 2005; 35 01 S73 S76
322. Papadopoulou A., Gerdemann U., Katari U. L., et al. Activity of broad-spectrum T cells as treatment for AdV, EBV, CMV, BKV, and HHV6 infections after HSCT. Sci Transl Med: 2014; 6 242 242ra83
323. Gerdemann U., Katari U. L., Papadopoulou A., et al. Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant. Mol Ther: 2013; 21 11 2113 2121
324. Feucht J., Opherk K., Lang P., et al. Adoptive T-cell therapy with hexon-specific Th1 cells as a treatment of refractory adenovirus infection after HSCT. Blood: 2015; 125 12 1986 1994
325. Binn L. N., Sanchez J. L., Gaydos J. C. Emergence of adenovirus type 14 in US military recruits-a new challenge. J Infect Dis: 2007; 196 10 1436 1437