Disseminated adenovirus disease in heart transplant recipient presenting with conjunctivitis

Transplant Infectious Disease

Volumn 17, Issue 1, 2015, Pages 125-128

  Bruminhent, J ^a   Athas, D M ^b   Hess, B D ^b   Flomenberg, P ^b  

^a MAYO CLINIC   (United States)

^b Division of Infectious Diseases and Environmental Medicine Department of Medicine Thomas Jefferson University   (United States)

Author keywords

Adenovirus; Cidofovir; Conjunctivitis; Heart transplantation; Pneumonitis

Indexed keywords

AZTREONAM; BASILIXIMAB; CIDOFOVIR; IMMUNOGLOBULIN; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; PROBENECID; TACROLIMUS; VANCOMYCIN; ANTIVIRUS AGENT; CYTOSINE; PHOSPHONIC ACID DERIVATIVE;

ADENOVIRIDAE; ADENOVIRUS INFECTION; AGED; ANTIBIOTIC THERAPY; ANTIVIRAL THERAPY; ARTICLE; BRONCHOSCOPY; CARDIAC GRAFT REJECTION; CASE REPORT; CHEMOSIS; CHILL; CHRONIC KIDNEY DISEASE; COMPUTER ASSISTED TOMOGRAPHY; CONJUNCTIVITIS; COUGHING; DECREASED APPETITE; DISEASE SEVERITY; DRUG DOSE REDUCTION; DRUG HYPERSENSITIVITY; DRUG WITHDRAWAL; DYSPNEA; FEVER; GRAFT RECIPIENT; HEART TRANSPLANTATION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LABORATORY TEST; LOW DRUG DOSE; LUNG EXAMINATION; LUNG LAVAGE; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; NAUSEA; NONISCHEMIC CARDIOMYOPATHY; OXYGEN SATURATION; PHYSICAL EXAMINATION; PLEURISY; PNEUMONIA; PRIORITY JOURNAL; REHYDRATION; RISK REDUCTION; THORAX PAIN; THORAX RADIOGRAPHY; VIRUS PNEUMONIA; VOMITING; ADENOVIRUS INFECTIONS, HUMAN; ADVERSE EFFECTS; ANALOGS AND DERIVATIVES; DRUG EFFECTS; HUMAN ADENOVIRUS C; IMMUNOCOMPROMISED PATIENT; PNEUMONIA, VIRAL; POSTOPERATIVE COMPLICATIONS;

ADENOVIRUS INFECTIONS, HUMAN; ADENOVIRUSES, HUMAN; AGED; ANTIVIRAL AGENTS; CONJUNCTIVITIS; CYTOSINE; HEART TRANSPLANTATION; HUMANS; IMMUNOCOMPROMISED HOST; IMMUNOSUPPRESSION; MALE; ORGANOPHOSPHONATES; PNEUMONIA, VIRAL; POSTOPERATIVE COMPLICATIONS; TRANSPLANT RECIPIENTS;

EID: 84923227586     PISSN: 13982273     EISSN: 13993062     Source Type: Journal    
DOI: 10.1111/tid.12342     Document Type: Article

References (15)

1. Ison MG. Adenovirus infections in transplant recipients. Clin Infect Dis 2006; 43 (3): 331-339.
2. Florescu DF, Kwon JY, Dumitru I. Adenovirus infections in heart transplantation. Cardiol Rev 2013; 21 (4): 203-206.
3. Florescu DF, Hoffman JA. Adenovirus in solid organ transplantation. Am J Transplant 2013; 13 (Suppl 4): 206-211.
4. Humar A, Kumar D, Mazzulli T, et al. A surveillance study of adenovirus infection in adult solid organ transplant recipients. Am J Transplant 2005; 5 (10): 2555-2559.
5. Leruez-Ville M, Minard V, Lacaille F, et al. Real-time blood plasma polymerase chain reaction for management of disseminated adenovirus infection. Clin Infect Dis 2004; 38 (1): 45-52.
6. Watcharananan SP, Avery R, Ingsathit A, et al. Adenovirus disease after kidney transplantation: course of infection and outcome in relation to blood viral load and immune recovery. Am J Transplant 2011; 11 (6): 1308-1314.
7. Ivan D, Frazier OH, Abrams J. Fatal disseminated adenoviral infection in an adult heart transplant patient. J Heart Lung Transpl 2004; 23 (10): 1209-1212.
8. Refaat M, McNamara D, Teuteberg J, et al. Successful cidofovir treatment in an adult heart transplant recipient with severe adenovirus pneumonia. J Heart Lung Transplant 2008; 27 (6): 699-700.
9. Ljungman P, Ribaud P, Eyrich M, et al. Cidofovir for adenovirus infections after allogeneic hematopoietic stem cell transplantation: a survey by the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant 2003; 31 (6): 481-486.
10. Neofytos D, Ojha A, Mookerjee B, et al. Treatment of adenovirus disease in stem cell transplant recipients with cidofovir. Biol Blood Marrow Transplant 2007; 13 (1): 74-81.
11. Florescu DF, Islam MK, Mercer DF, et al. Adenovirus infections in pediatric small bowel transplant recipients. Transplantation 2010; 90: 198-200.
12. Hoffman JA, Shah AJ, Ross LA, Kapoor N. Adenoviral infections and a prospective trial of cidofovir in pediatric hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2001; 7 (7): 388-394.
13. Saquib R, Melton LB, Chandrakantan A, et al. Disseminated adenovirus infection in renal transplant recipients: the role of cidofovir and intravenous immunoglobulin. Transpl Infect Dis 2010; 12 (1): 77-83.
14. Doan ML, Mallory GB, Kaplan SL, et al. Treatment of adenovirus pneumonia with cidofovir in pediatric lung transplant recipients. J Heart Lung Transplant 2007; 26 (9): 883-889.
15. Seidemann K, Heim A, Pfister ED, et al. Monitoring of adenovirus infection in pediatric transplant recipients by quantitative PCR: report of six cases and review of the literature. Am J Transplant 2004; 4 (12): 2102-2108.