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Volumn 9, Issue 5, 2016, Pages 1263-1277

IL-10 downregulates CXCR3 expression on Th1 cells and interferes with their migration to intestinal inflammatory sites

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA DEC 205 MONOCLONAL ANTIBODY; CELL SURFACE RECEPTOR; CHEMOKINE RECEPTOR CXCR3; DEC 205 PROTEIN; INTERLEUKIN 10; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; CD4 ANTIGEN; CXCR3 PROTEIN, MOUSE; DEC-205 RECEPTOR; IL10 PROTEIN, MOUSE; LECTIN; LEUKOCYTE ANTIGEN; MINOR HISTOCOMPATIBILITY ANTIGEN;

EID: 84982273080     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2015.132     Document Type: Article
Times cited : (36)

References (42)
  • 1
    • 78649526238 scopus 로고    scopus 로고
    • Mechanisms of impaired regulation by CD4(+)CD25(+) FOXP3(+) regulatory T cells in human autoimmune diseases
    • Buckner, J.H. Mechanisms of impaired regulation by CD4(+)CD25(+) FOXP3(+) regulatory T cells in human autoimmune diseases. Nat. Rev. Immunol. 10, 849-859 (2010
    • (2010) Nat. Rev. Immunol , vol.10 , pp. 849-859
    • Buckner, J.H.1
  • 2
    • 32044451548 scopus 로고    scopus 로고
    • Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: The classic-i trial
    • Hanauer, S.B., et al. Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial. Gastroenterology 130, 323-333 (2006
    • (2006) Gastroenterology , vol.130 , pp. 323-333
    • Hanauer, S.B.1
  • 3
    • 77950527019 scopus 로고    scopus 로고
    • Emerging prognostic markers to determine Crohn's disease natural history and improve management strategies: A review of recent literature
    • Lichtenstein, G.R. Emerging prognostic markers to determine Crohn's disease natural history and improve management strategies: a review of recent literature. Gastroenterol. Hepatol. (NY) 6, 99-107 (2010
    • (2010) Gastroenterol. Hepatol. (NY , vol.6 , pp. 99-107
    • Lichtenstein, G.R.1
  • 5
    • 71649084107 scopus 로고    scopus 로고
    • T cells, dendritic cells and epithelial cells in intestinal homeostasis
    • Westendorf, A.M., Fleissner, D., Hansen, W., & Buer, J. T cells, dendritic cells and epithelial cells in intestinal homeostasis. Int. J. Med. Microbiol. 300, 11-18 (2010
    • (2010) Int. J. Med. Microbiol , vol.300 , pp. 11-18
    • Westendorf, A.M.1    Fleissner, D.2    Hansen, W.3    Buer, J.4
  • 7
    • 0037122011 scopus 로고    scopus 로고
    • Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class i products and peripheral CD8+ T cell tolerance
    • Bonifaz, L., et al. Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. J. Exp. Med. 196, 1627-1638 (2002
    • (2002) J. Exp. Med , vol.196 , pp. 1627-1638
    • Bonifaz, L.1
  • 8
    • 0034735552 scopus 로고    scopus 로고
    • The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments
    • Mahnke, K., et al. The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. J. Cell Biol. 151, 673-684 (2000
    • (2000) J. Cell Biol , vol.151 , pp. 673-684
    • Mahnke, K.1
  • 9
    • 84859899776 scopus 로고    scopus 로고
    • Targeting of the hNC16A collagen domain to dendritic cells induces tolerance to human type XVII collagen
    • Ettinger, M., et al. Targeting of the hNC16A collagen domain to dendritic cells induces tolerance to human type XVII collagen. Exp. Dermatol. 21, 395-398 (2012
    • (2012) Exp. Dermatol , vol.21 , pp. 395-398
    • Ettinger, M.1
  • 10
    • 29244435493 scopus 로고    scopus 로고
    • Inducing and expanding regulatory Tcell populations by foreign antigen
    • Kretschmer, K., et al. Inducing and expanding regulatory Tcell populations by foreign antigen. Nat. Immunol. 6, 1219-1227 (2005
    • (2005) Nat. Immunol , vol.6 , pp. 1219-1227
    • Kretschmer, K.1
  • 11
    • 44049086242 scopus 로고    scopus 로고
    • Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ Tcells in NOD mice
    • Mukhopadhaya, A., et al. Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ Tcells in NOD mice. Proc. Natl. Acad. Sci. USA 105, 6374-6379 (2008
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 6374-6379
    • Mukhopadhaya, A.1
  • 12
    • 84929103797 scopus 로고    scopus 로고
    • DEC205+ dendritic cell-targeted tolerogenic vaccination promotes immune tolerance in experimental autoimmune arthritis
    • Spiering, R., et al. DEC205+ dendritic cell-targeted tolerogenic vaccination promotes immune tolerance in experimental autoimmune arthritis. J. Immunol. 194, 4804-4813 (2015
    • (2015) J. Immunol , vol.194 , pp. 4804-4813
    • Spiering, R.1
  • 13
    • 0038792101 scopus 로고    scopus 로고
    • Induction of CD4+/CD25+ regulatory Tcells by targeting of antigens to immature dendritic cells
    • Mahnke, K., Qian, Y., Knop, J., & Enk, A.H. Induction of CD4+/CD25+ regulatory Tcells by targeting of antigens to immature dendritic cells. Blood 101, 4862-4869 (2003
    • (2003) Blood , vol.101 , pp. 4862-4869
    • Mahnke, K.1    Qian, Y.2    Knop, J.3    Enk, A.H.4
  • 14
    • 33644691658 scopus 로고    scopus 로고
    • On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes
    • Bruder, D., et al. On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes. Diabetes 54, 3395-3401 (2005
    • (2005) Diabetes , vol.54 , pp. 3395-3401
    • Bruder, D.1
  • 15
    • 79952116856 scopus 로고    scopus 로고
    • Dendritic cell-targeted pancreatic beta-cell antigen leads to conversion of self-reactive CD4(+) T cells into regulatory T cells and promotes immunotolerance in NOD mice
    • Petzold, C., Riewaldt, J., Koenig, T., Schallenberg, S., & Kretschmer, K. Dendritic cell-targeted pancreatic beta-cell antigen leads to conversion of self-reactive CD4(+) T cells into regulatory T cells and promotes immunotolerance in NOD mice. Rev. Diabet. Stud. 7, 47-61 (2010
    • (2010) Rev. Diabet. Stud , vol.7 , pp. 47-61
    • Petzold, C.1    Riewaldt, J.2    Koenig, T.3    Schallenberg, S.4    Kretschmer, K.5
  • 16
    • 78049267645 scopus 로고    scopus 로고
    • Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells
    • Stern, J.N., et al. Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells. Proc. Natl. Acad. Sci. USA 107, 17280-17285 (2010
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 17280-17285
    • Stern, J.N.1
  • 17
    • 84884216197 scopus 로고    scopus 로고
    • Targeting of autoantigens to DEC205(+) dendritic cells in vivo suppresses experimental allergic encephalomyelitis in mice
    • Ring, S., Maas, M., Nettelbeck, D.M., Enk, A.H., & Mahnke, K. Targeting of autoantigens to DEC205(+) dendritic cells in vivo suppresses experimental allergic encephalomyelitis in mice. J. Immunol. 191, 2938-2947 (2013
    • (2013) J. Immunol , vol.191 , pp. 2938-2947
    • Ring, S.1    Maas, M.2    Nettelbeck, D.M.3    Enk, A.H.4    Mahnke, K.5
  • 18
    • 4344591762 scopus 로고    scopus 로고
    • T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction of Th1 mediated immunopathology in Crohn's disease
    • Matsuoka, K., et al. T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction of Th1 mediated immunopathology in Crohn's disease. Gut 53, 1303-1308 (2004
    • (2004) Gut , vol.53 , pp. 1303-1308
    • Matsuoka, K.1
  • 19
    • 0037029649 scopus 로고    scopus 로고
    • The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease
    • Neurath, M.F., et al. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease. J. Exp. Med. 195, 1129-1143 (2002
    • (2002) J. Exp. Med , vol.195 , pp. 1129-1143
    • Neurath, M.F.1
  • 20
    • 79954608612 scopus 로고    scopus 로고
    • Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation
    • Chaudhry, A., et al. Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation. Immunity 34, 566-578 (2011
    • (2011) Immunity , vol.34 , pp. 566-578
    • Chaudhry, A.1
  • 21
    • 0041845066 scopus 로고    scopus 로고
    • Inhibition of IFNgamma-inducible protein-10 abrogates colitis in IL-10-/-mice
    • Singh, U.P., Singh, S., Taub, D.D., & Lillard, J.W. Jr. Inhibition of IFNgamma-inducible protein-10 abrogates colitis in IL-10-/-mice. J. Immunol. 171, 1401-1406 (2003
    • (2003) J. Immunol , vol.171 , pp. 1401-1406
    • Singh, U.P.1    Singh, S.2    Taub, D.D.3    Lillard, J.W.4
  • 22
    • 23844499474 scopus 로고    scopus 로고
    • The simultaneous blockade of chemokine receptors CCR2 CCR5 and CXCR3 by a non-peptide chemokine receptor antagonist protects mice from dextran sodium sulfate-mediated colitis
    • Tokuyama, H., et al. The simultaneous blockade of chemokine receptors CCR2, CCR5 and CXCR3 by a non-peptide chemokine receptor antagonist protects mice from dextran sodium sulfate-mediated colitis. Int. Immunol. 17, 1023-1034 (2005
    • (2005) Int. Immunol , vol.17 , pp. 1023-1034
    • Tokuyama, H.1
  • 23
    • 0035162551 scopus 로고    scopus 로고
    • Chemokine receptor CXCR3 expression in inflammatory bowel disease
    • Yuan, Y.H., et al. Chemokine receptor CXCR3 expression in inflammatory bowel disease. Inflamm. Bowel Dis. 7, 281-286 (2001
    • (2001) Inflamm. Bowel Dis , vol.7 , pp. 281-286
    • Yuan, Y.H.1
  • 24
    • 84861816840 scopus 로고    scopus 로고
    • A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis
    • Yellin, M., et al. A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis. Arthritis Rheum. 64, 1730-1739 (2012
    • (2012) Arthritis Rheum , vol.64 , pp. 1730-1739
    • Yellin, M.1
  • 26
    • 2342646956 scopus 로고    scopus 로고
    • Bacterial flagellin is a dominant antigen in Crohn disease
    • Lodes, M.J., et al. Bacterial flagellin is a dominant antigen in Crohn disease. J. Clin. Invest. 113, 1296-1306 (2004
    • (2004) J. Clin. Invest , vol.113 , pp. 1296-1306
    • Lodes, M.J.1
  • 27
    • 0033937341 scopus 로고    scopus 로고
    • Commensal bacteria as targets in Crohn's disease
    • Elson, C.O. Commensal bacteria as targets in Crohn's disease. Gastroenterology 119, 254-257 (2000
    • (2000) Gastroenterology , vol.119 , pp. 254-257
    • Elson, C.O.1
  • 28
    • 59849117418 scopus 로고    scopus 로고
    • Enhanced CBir1-specific innate and adaptive immune responses in Crohn's disease
    • Shen, C., Landers, C.J., Derkowski, C., Elson, C.O., & Targan, S.R. Enhanced CBir1-specific innate and adaptive immune responses in Crohn's disease. Inflamm. Bowel Dis. 14, 1641-1651 (2008
    • (2008) Inflamm. Bowel Dis , vol.14 , pp. 1641-1651
    • Shen, C.1    Landers, C.J.2    Derkowski, C.3    Elson, C.O.4    Targan, S.R.5
  • 29
    • 33847664069 scopus 로고    scopus 로고
    • Anti-flagellin (CBir1) phenotypic and genetic Crohn's disease associations
    • Papadakis, K.A., et al. Anti-flagellin (CBir1) phenotypic and genetic Crohn's disease associations. Inflamm. Bowel Dis. 13, 524-530 (2007
    • (2007) Inflamm. Bowel Dis , vol.13 , pp. 524-530
    • Papadakis, K.A.1
  • 30
    • 20444441016 scopus 로고    scopus 로고
    • Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease
    • Targan, S.R., et al. Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease. Gastroenterology 128, 2020-2028 (2005
    • (2005) Gastroenterology , vol.128 , pp. 2020-2028
    • Targan, S.R.1
  • 31
    • 0029813545 scopus 로고    scopus 로고
    • Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses
    • Berg, D.J., et al. Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses. J. Clin. Invest. 98, 1010-1020 (1996
    • (1996) J. Clin. Invest , vol.98 , pp. 1010-1020
    • Berg, D.J.1
  • 32
    • 84879109909 scopus 로고    scopus 로고
    • A single strain of Clostridium butyricum induces intestinal IL-10-producing macrophages to suppress acute experimental colitis in mice
    • Hayashi, A., et al. A single strain of Clostridium butyricum induces intestinal IL-10-producing macrophages to suppress acute experimental colitis in mice. Cell Host. Microbe 13, 711-722 (2013
    • (2013) Cell Host. Microbe , vol.13 , pp. 711-722
    • Hayashi, A.1
  • 34
    • 0025763807 scopus 로고
    • IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells
    • Fiorentino, D.F., et al. IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J. Immunol. 146, 3444-3451 (1991
    • (1991) J. Immunol , vol.146 , pp. 3444-3451
    • Fiorentino, D.F.1
  • 35
    • 34547788180 scopus 로고    scopus 로고
    • A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
    • Coombes, J.L., et al. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J. Exp. Med. 204, 1757-1764 (2007
    • (2007) J. Exp. Med , vol.204 , pp. 1757-1764
    • Coombes, J.L.1
  • 36
    • 34547757390 scopus 로고    scopus 로고
    • Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
    • Sun, C.M., et al. Small intestine lamina propria dendritic cells promote De novo generation of Foxp3 T reg cells via retinoic acid. J. Exp. Med. 204, 1775-1785 (2007
    • (2007) J. Exp. Med , vol.204 , pp. 1775-1785
    • Sun, C.M.1
  • 37
    • 0033818104 scopus 로고    scopus 로고
    • Amonoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells
    • Guo, M., et al. Amonoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells. Hum. Immunol. 61, 729-738 (2000
    • (2000) Hum. Immunol , vol.61 , pp. 729-738
    • Guo, M.1
  • 38
    • 19944416542 scopus 로고    scopus 로고
    • CD4+ Tcell mediated intestinal immunity: Chronic inflammation versus immune regulation
    • Westendorf, A.M., et al. CD4+ Tcell mediated intestinal immunity: chronic inflammation versus immune regulation. Gut 54, 60-69 (2005
    • (2005) Gut , vol.54 , pp. 60-69
    • Westendorf, A.M.1
  • 39
    • 0028359368 scopus 로고
    • Thymic selection of CD8+ single positive cellswith a class II major histocompatibility complex-restricted receptor
    • Kirberg, J., et al. Thymic selection of CD8+ single positive cellswith a class II major histocompatibility complex-restricted receptor. J. Exp. Med. 180, 25-34 (1994
    • (1994) J. Exp. Med , vol.180 , pp. 25-34
    • Kirberg, J.1
  • 40
    • 9244237038 scopus 로고    scopus 로고
    • Tcell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation
    • Roers, A., et al. Tcell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation. J. Exp. Med. 200, 1289-1297 (2004
    • (2004) J. Exp. Med , vol.200 , pp. 1289-1297
    • Roers, A.1
  • 41
    • 34447275920 scopus 로고    scopus 로고
    • Notch-RBP-J signaling controls the homeostasis ofCD8-dendritic cells in the spleen
    • Caton, M.L., Smith-Raska, M.R., & Reizis, B. Notch-RBP-J signaling controls the homeostasis ofCD8-dendritic cells in the spleen. J. Exp. Med. 204, 1653-1664 (2007
    • (2007) J. Exp. Med , vol.204 , pp. 1653-1664
    • Caton, M.L.1    Smith-Raska, M.R.2    Reizis, B.3
  • 42
    • 0031897801 scopus 로고    scopus 로고
    • Defective TCR expression in transgenic mice constructed using cDNA-based alpha-and beta-chain genes under the control of heterologous regulatory elements
    • Barnden, M.J., Allison, J., Heath, W.R., & Carbone, F.R. Defective TCR expression in transgenic mice constructed using cDNA-based alpha-and beta-chain genes under the control of heterologous regulatory elements. Immunol. Cell Biol. 76, 34-40 (1998
    • (1998) Immunol. Cell Biol , vol.76 , pp. 34-40
    • Barnden, M.J.1    Allison, J.2    Heath, W.R.3    Carbone, F.R.4


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