-
1
-
-
33244454778
-
International trends in admissions and drug sales for asthma
-
Gupta, R., Anderson, H. R., Strachan, D. P., Maier, W. & Watson, L. International trends in admissions and drug sales for asthma. Int J Tuberc Lung Dis 10, 138-145 (2006).
-
(2006)
Int J Tuberc Lung Dis
, vol.10
, pp. 138-145
-
-
Gupta, R.1
Anderson, H.R.2
Strachan, D.P.3
Maier, W.4
Watson, L.5
-
2
-
-
1642302916
-
The epidemic of asthma and allergy
-
Holgate, S. T. The epidemic of asthma and allergy. J R Soc Med 97, 103-110 (2004).
-
(2004)
J R Soc Med
, vol.97
, pp. 103-110
-
-
Holgate, S.T.1
-
3
-
-
78649868199
-
The role of the T cell in asthma
-
1092-1093
-
Robinson, D. S. The role of the T cell in asthma. J Allergy Clin Immunol 126, 1081-1091, 1092-1093 (2010).
-
(2010)
J Allergy Clin Immunol
, vol.126
, pp. 1081-1091
-
-
Robinson, D.S.1
-
4
-
-
46249101518
-
How regulatory T cells work
-
Vignali, D. A., Collison, L. W. & Workman, C. J. How regulatory T cells work. NAT REV IMMUNOL 8, 523-532 (2008).
-
(2008)
NAT REV IMMUNOL
, vol.8
, pp. 523-532
-
-
Vignali, D.A.1
Collison, L.W.2
Workman, C.J.3
-
5
-
-
84879470120
-
Frequency and activation of CD4+ CD25 FoxP3+ regulatory T cells in peripheral blood from children with atopic allergy
-
Stelmaszczyk-Emmel, A., Zawadzka-Krajewska, A., Szypowska, A., Kulus, M. & Demkow, U. Frequency and activation of CD4+ CD25 FoxP3+ regulatory T cells in peripheral blood from children with atopic allergy. Int Arch Allergy Immunol 162, 16-24 (2013).
-
(2013)
Int Arch Allergy Immunol
, vol.162
, pp. 16-24
-
-
Stelmaszczyk-Emmel, A.1
Zawadzka-Krajewska, A.2
Szypowska, A.3
Kulus, M.4
Demkow, U.5
-
6
-
-
28544444024
-
Resolution of airway inflammation and hyperreactivity after in vivo transfer of CD4+ CD25+ regulatory T cells is interleukin 10 dependent
-
Kearley, J., Barker, J. E., Robinson, D. S. & Lloyd, C. M. Resolution of airway inflammation and hyperreactivity after in vivo transfer of CD4+ CD25+ regulatory T cells is interleukin 10 dependent. J EXP MED 202, 1539-1547 (2005).
-
(2005)
J EXP MED
, vol.202
, pp. 1539-1547
-
-
Kearley, J.1
Barker, J.E.2
Robinson, D.S.3
Lloyd, C.M.4
-
7
-
-
0034327264
-
T regulatory cells 1 inhibit a Th2-specific response in vivo
-
Cottrez, F., Hurst, S. D., Coffman, R. L. & Groux, H. T regulatory cells 1 inhibit a Th2-specific response in vivo. J IMMUNOL 165, 4848-4853 (2000).
-
(2000)
J IMMUNOL
, vol.165
, pp. 4848-4853
-
-
Cottrez, F.1
Hurst, S.D.2
Coffman, R.L.3
Groux, H.4
-
8
-
-
58149191877
-
Suppression of murine allergic airway disease by IL-2:anti-IL-2 monoclonal antibody-induced regulatory T cells
-
Wilson, M. S. et al. Suppression of murine allergic airway disease by IL-2:anti-IL-2 monoclonal antibody-induced regulatory T cells. J IMMUNOL 181, 6942-6954 (2008).
-
(2008)
J IMMUNOL
, vol.181
, pp. 6942-6954
-
-
Wilson, M.S.1
-
9
-
-
1642308173
-
Differential response of murine CD4+ CD25+ and CD4+ CD25- T cells to dexamethasone-induced cell death
-
Chen, X., Murakami, T., Oppenheim, J. J. & Howard, O. M. Differential response of murine CD4+ CD25+ and CD4+ CD25- T cells to dexamethasone-induced cell death. EUR J IMMUNOL 34, 859-869 (2004).
-
(2004)
EUR J IMMUNOL
, vol.34
, pp. 859-869
-
-
Chen, X.1
Murakami, T.2
Oppenheim, J.J.3
Howard, O.M.4
-
10
-
-
33747414436
-
Glucocorticoid amplifies IL-2-dependent expansion of functional FoxP3(+ )CD4(+ )CD25(+ ) T regulatory cells in vivo and enhances their capacity to suppress EAE
-
Chen, X., Oppenheim, J. J., Winkler-Pickett, R. T., Ortaldo, J. R. & Howard, O. M. Glucocorticoid amplifies IL-2-dependent expansion of functional FoxP3(+ )CD4(+ )CD25(+ ) T regulatory cells in vivo and enhances their capacity to suppress EAE. EUR J IMMUNOL 36, 2139-2149 (2006).
-
(2006)
EUR J IMMUNOL
, vol.36
, pp. 2139-2149
-
-
Chen, X.1
Oppenheim, J.J.2
Winkler-Pickett, R.T.3
Ortaldo, J.R.4
Howard, O.M.5
-
11
-
-
79957830804
-
Alleviating allergic airway diseases by means of short-term administration of IL-2 and dexamethasone
-
Ma, J. et al. Alleviating allergic airway diseases by means of short-term administration of IL-2 and dexamethasone. J Allergy Clin Immunol 127, 1447-1456 (2011).
-
(2011)
J Allergy Clin Immunol
, vol.127
, pp. 1447-1456
-
-
Ma, J.1
-
12
-
-
84862893004
-
Spatiotemporally separated antigen uptake by alveolar dendritic cells and airway presentation to T cells in the lung
-
Thornton, E. E. et al. Spatiotemporally separated antigen uptake by alveolar dendritic cells and airway presentation to T cells in the lung. J EXP MED 209, 1183-1199 (2012).
-
(2012)
J EXP MED
, vol.209
, pp. 1183-1199
-
-
Thornton, E.E.1
-
13
-
-
0037385330
-
Foxp3 programs the development and function of CD4+ CD25+ regulatory T cells
-
Fontenot, J. D., Gavin, M. A. & Rudensky, A. Y. Foxp3 programs the development and function of CD4+ CD25+ regulatory T cells. NAT IMMUNOL 4, 330-336 (2003).
-
(2003)
NAT IMMUNOL
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
14
-
-
55749111387
-
The pharmacology of PEGylation: Balancing PD with PK to generate novel therapeutics
-
Fishburn, C. S. The pharmacology of PEGylation: balancing PD with PK to generate novel therapeutics. J Pharm Sci 97, 4167-4183 (2008).
-
(2008)
J Pharm Sci
, vol.97
, pp. 4167-4183
-
-
Fishburn, C.S.1
-
15
-
-
56049109272
-
Glucocorticoid-induced apoptosis requires FOXO3A activity
-
Ma, J. et al. Glucocorticoid-induced apoptosis requires FOXO3A activity. Biochem Biophys Res Commun 377, 894-898 (2008).
-
(2008)
Biochem Biophys Res Commun
, vol.377
, pp. 894-898
-
-
Ma, J.1
-
16
-
-
1642398043
-
Interleukin 2 plays a central role in Th2 differentiation
-
Cote-Sierra, J. et al. Interleukin 2 plays a central role in Th2 differentiation. Proc Natl Acad Sci USA 101, 3880-3885 (2004).
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3880-3885
-
-
Cote-Sierra, J.1
-
17
-
-
0037449504
-
Suppression of allergen reactive Th2 mediated responses and pulmonary eosinophilia by intranasal administration of an immunodominant peptide is linked to IL-10 production
-
Hall, G., Houghton, C. G., Rahbek, J. U., Lamb, J. R. & Jarman, E. R. Suppression of allergen reactive Th2 mediated responses and pulmonary eosinophilia by intranasal administration of an immunodominant peptide is linked to IL-10 production. VACCINE 21, 549-561 (2003).
-
(2003)
VACCINE
, vol.21
, pp. 549-561
-
-
Hall, G.1
Houghton, C.G.2
Rahbek, J.U.3
Lamb, J.R.4
Jarman, E.R.5
-
18
-
-
0037504093
-
Induction of IL-10+ CD4+ CD25+ T cells by grass pollen immunotherapy
-
Francis, J. N., Till, S. J. & Durham, S. R. Induction of IL-10+ CD4+ CD25+ T cells by grass pollen immunotherapy. J Allergy Clin Immunol 111, 1255-1261 (2003).
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 1255-1261
-
-
Francis, J.N.1
Till, S.J.2
Durham, S.R.3
-
19
-
-
38349096223
-
Expansion of circulating Foxp3+D25bright CD4+ T cells during specific venom immunotherapy
-
Pereira-Santos, M. C. et al. Expansion of circulating Foxp3+D25bright CD4+ T cells during specific venom immunotherapy. CLIN EXP ALLERGY 38, 291-297 (2008).
-
(2008)
CLIN EXP ALLERGY
, vol.38
, pp. 291-297
-
-
Pereira-Santos, M.C.1
-
20
-
-
34547749066
-
Emerging challenges in regulatory T cell function and biology
-
Sakaguchi, S. & Powrie, F. Emerging challenges in regulatory T cell function and biology. SCIENCE 317, 627-629 (2007).
-
(2007)
SCIENCE
, vol.317
, pp. 627-629
-
-
Sakaguchi, S.1
Powrie, F.2
-
21
-
-
33645498741
-
CD137-mediated immunotherapy for allergic asthma
-
Polte, T. et al. CD137-mediated immunotherapy for allergic asthma. J CLIN INVEST 116, 1025-1036 (2006).
-
(2006)
J CLIN INVEST
, vol.116
, pp. 1025-1036
-
-
Polte, T.1
-
22
-
-
0042235397
-
Potential adverse effects of the inhaled corticosteroids
-
479
-
Kelly, H. W. & Nelson, H. S. Potential adverse effects of the inhaled corticosteroids. J Allergy Clin Immunol 112, 469-478, 479 (2003).
-
(2003)
J Allergy Clin Immunol
, vol.112
, pp. 469-478
-
-
Kelly, H.W.1
Nelson, H.S.2
-
23
-
-
84919346772
-
Glucocorticoids decrease Treg cell numbers in lungs of allergic mice
-
Olsen, P. C. et al. Glucocorticoids decrease Treg cell numbers in lungs of allergic mice. EUR J PHARMACOL 747, 52-58 (2015).
-
(2015)
EUR J PHARMACOL
, vol.747
, pp. 52-58
-
-
Olsen, P.C.1
-
24
-
-
34247526094
-
Quantitative and functional impairment of pulmonary CD4+ CD25hi regulatory T cells in pediatric asthma
-
Hartl, D. et al. Quantitative and functional impairment of pulmonary CD4+ CD25hi regulatory T cells in pediatric asthma. J Allergy Clin Immunol 119, 1258-1266 (2007).
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 1258-1266
-
-
Hartl, D.1
-
25
-
-
0343484923
-
Inhibition of Th1 immune response by glucocorticoids: Dexamethasone selectively inhibits IL-12-induced Stat4 phosphorylation in T lymphocytes
-
Franchimont, D. et al. Inhibition of Th1 immune response by glucocorticoids: dexamethasone selectively inhibits IL-12-induced Stat4 phosphorylation in T lymphocytes. J IMMUNOL 164, 1768-1774 (2000).
-
(2000)
J IMMUNOL
, vol.164
, pp. 1768-1774
-
-
Franchimont, D.1
-
26
-
-
0036467522
-
CD25+ CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10- dependent immunoregulation of alloresponses
-
Kingsley, C. I., Karim, M., Bushell, A. R. & Wood, K. J. CD25+ CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10- dependent immunoregulation of alloresponses. J IMMUNOL 168, 1080-1086 (2002).
-
(2002)
J IMMUNOL
, vol.168
, pp. 1080-1086
-
-
Kingsley, C.I.1
Karim, M.2
Bushell, A.R.3
Wood, K.J.4
-
27
-
-
27844497945
-
FOXO transcription factors at the interface between longevity and tumor suppression
-
Greer, E. L. & Brunet, A. FOXO transcription factors at the interface between longevity and tumor suppression. ONCOGENE 24, 7410-7425 (2005).
-
(2005)
ONCOGENE
, vol.24
, pp. 7410-7425
-
-
Greer, E.L.1
Brunet, A.2
-
28
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet, A. et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. CELL 96, 857-868 (1999).
-
(1999)
CELL
, vol.96
, pp. 857-868
-
-
Brunet, A.1
-
29
-
-
20444497875
-
FOXO-dependent expression of the proapoptotic protein Bim: Pivotal role for apoptosis signaling in endothelial progenitor cells
-
Urbich, C. et al. FOXO-dependent expression of the proapoptotic protein Bim: pivotal role for apoptosis signaling in endothelial progenitor cells. FASEB J 19, 974-976 (2005).
-
(2005)
FASEB J
, vol.19
, pp. 974-976
-
-
Urbich, C.1
-
30
-
-
0036120725
-
Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors
-
Kops, G. J. et al. Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors. MOL CELL BIOL 22, 2025-2036 (2002).
-
(2002)
MOL CELL BIOL
, vol.22
, pp. 2025-2036
-
-
Kops, G.J.1
-
31
-
-
56049109272
-
Glucocorticoid-induced apoptosis requires FOXO3A activity
-
Ma, J. et al. Glucocorticoid-induced apoptosis requires FOXO3A activity. Biochem Biophys Res Commun 377, 894-898 (2008).
-
(2008)
Biochem Biophys Res Commun
, vol.377
, pp. 894-898
-
-
Ma, J.1
-
32
-
-
0027394657
-
The IL-2/IL-2 receptor system: A current overview
-
Taniguchi, T. & Minami, Y. The IL-2/IL-2 receptor system: a current overview. CELL 73, 5-8 (1993).
-
(1993)
CELL
, vol.73
, pp. 5-8
-
-
Taniguchi, T.1
Minami, Y.2
-
33
-
-
33645465526
-
Selective stimulation of T cell subsets with antibody-cytokine immune complexes
-
Boyman, O., Kovar, M., Rubinstein, M. P., Surh, C. D. & Sprent, J. Selective stimulation of T cell subsets with antibody-cytokine immune complexes. SCIENCE 311, 1924-1927 (2006).
-
(2006)
SCIENCE
, vol.311
, pp. 1924-1927
-
-
Boyman, O.1
Kovar, M.2
Rubinstein, M.P.3
Surh, C.D.4
Sprent, J.5
-
34
-
-
0035876913
-
A role for TGF-beta in the generation and expansion of CD4+ CD25+ regulatory T cells from human peripheral blood
-
Yamagiwa, S., Gray, J. D., Hashimoto, S. & Horwitz, D. A. A role for TGF-beta in the generation and expansion of CD4+ CD25+ regulatory T cells from human peripheral blood. J IMMUNOL 166, 7282-7289 (2001).
-
(2001)
J IMMUNOL
, vol.166
, pp. 7282-7289
-
-
Yamagiwa, S.1
Gray, J.D.2
Hashimoto, S.3
Horwitz, D.A.4
-
35
-
-
84857646605
-
The role of interleukin-2 during homeostasis and activation of the immune system
-
Boyman, O. & Sprent, J. The role of interleukin-2 during homeostasis and activation of the immune system. NAT REV IMMUNOL 12, 180-190 (2012).
-
(2012)
NAT REV IMMUNOL
, vol.12
, pp. 180-190
-
-
Boyman, O.1
Sprent, J.2
-
36
-
-
49649094299
-
IL-2 receptor beta-chain signaling controls immunosuppressive CD4+ T cells in the draining lymph nodes and lung during allergic airway inflammation in vivo
-
Doganci, A. et al. IL-2 receptor beta-chain signaling controls immunosuppressive CD4+ T cells in the draining lymph nodes and lung during allergic airway inflammation in vivo. J IMMUNOL 181, 1917-1926 (2008).
-
(2008)
J IMMUNOL
, vol.181
, pp. 1917-1926
-
-
Doganci, A.1
-
37
-
-
60149085254
-
A low interleukin-2 receptor signaling threshold supports the development and homeostasis of T regulatory cells
-
Yu, A., Zhu, L., Altman, N. H. & Malek, T. R. A low interleukin-2 receptor signaling threshold supports the development and homeostasis of T regulatory cells. IMMUNITY 30, 204-217 (2009).
-
(2009)
IMMUNITY
, vol.30
, pp. 204-217
-
-
Yu, A.1
Zhu, L.2
Altman, N.H.3
Malek, T.R.4
-
38
-
-
0026017971
-
Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis
-
Lenardo, M. J. Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis. NATURE 353, 858-861 (1991).
-
(1991)
NATURE
, vol.353
, pp. 858-861
-
-
Lenardo, M.J.1
-
39
-
-
45549122275
-
IL-13 as a therapeutic target for respiratory disease
-
Kasaian, M. T. & Miller, D. K. IL-13 as a therapeutic target for respiratory disease. BIOCHEM PHARMACOL 76, 147-155 (2008).
-
(2008)
BIOCHEM PHARMACOL
, vol.76
, pp. 147-155
-
-
Kasaian, M.T.1
Miller, D.K.2
-
40
-
-
0031707007
-
Human mast cells produce IL-13 by high-affinity IgE receptor cross-linking: Enhanced IL-13 production by IL-4-primed human mast cells
-
Toru, H., Pawankar, R., Ra, C., Yata, J. & Nakahata, T. Human mast cells produce IL-13 by high-affinity IgE receptor cross-linking: enhanced IL-13 production by IL-4-primed human mast cells. J Allergy Clin Immunol 102, 491-502 (1998).
-
(1998)
J Allergy Clin Immunol
, vol.102
, pp. 491-502
-
-
Toru, H.1
Pawankar, R.2
Ra, C.3
Yata, J.4
Nakahata, T.5
-
41
-
-
42149137962
-
Recent advances in the role of NKT cells in allergic diseases and asthma
-
Stock, P. & Akbari, O. Recent advances in the role of NKT cells in allergic diseases and asthma. Curr Allergy Asthma Rep 8, 165-170 (2008).
-
(2008)
Curr Allergy Asthma Rep
, vol.8
, pp. 165-170
-
-
Stock, P.1
Akbari, O.2
-
42
-
-
0032909720
-
IL-13 production by NK cells: IL-13-producing NK and T cells are present in vivo in the absence of IFN-gamma
-
Hoshino, T., Winkler-Pickett, R. T., Mason, A. T., Ortaldo, J. R. & Young, H. A. IL-13 production by NK cells: IL-13-producing NK and T cells are present in vivo in the absence of IFN-gamma. J IMMUNOL 162, 51-59 (1999).
-
(1999)
J IMMUNOL
, vol.162
, pp. 51-59
-
-
Hoshino, T.1
Winkler-Pickett, R.T.2
Mason, A.T.3
Ortaldo, J.R.4
Young, H.A.5
-
43
-
-
0020701826
-
Natural killer (NK) cells as a responder to interleukin 2 (IL 2). I. Proliferative response and establishment of cloned cells
-
Suzuki, R., Handa, K., Itoh, K. & Kumagai, K. Natural killer (NK) cells as a responder to interleukin 2 (IL 2). I. Proliferative response and establishment of cloned cells. J IMMUNOL 130, 981-987 (1983).
-
(1983)
J IMMUNOL
, vol.130
, pp. 981-987
-
-
Suzuki, R.1
Handa, K.2
Itoh, K.3
Kumagai, K.4
-
44
-
-
0037911660
-
Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity
-
Akbari, O. et al. Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. NAT MED 9, 582-588 (2003).
-
(2003)
NAT MED
, vol.9
, pp. 582-588
-
-
Akbari, O.1
-
45
-
-
0037418042
-
Nicotine strongly activates dendritic cell-mediated adaptive immunity: Potential role for progression of atherosclerotic lesions
-
Aicher, A. et al. Nicotine strongly activates dendritic cell-mediated adaptive immunity: potential role for progression of atherosclerotic lesions. CIRCULATION 107, 604-611 (2003).
-
(2003)
CIRCULATION
, vol.107
, pp. 604-611
-
-
Aicher, A.1
-
46
-
-
0034193990
-
DO11.10 and OT-II T cells recognize a C-terminal ovalbumin 323-339 epitope
-
Robertson, J. M., Jensen, P. E. & Evavold, B. D. DO11.10 and OT-II T cells recognize a C-terminal ovalbumin 323-339 epitope. J IMMUNOL 164, 4706-4712 (2000).
-
(2000)
J IMMUNOL
, vol.164
, pp. 4706-4712
-
-
Robertson, J.M.1
Jensen, P.E.2
Evavold, B.D.3
|