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Volumn 162, Issue 1, 2013, Pages 16-24

Frequency and activation of CD4+CD25high FoxP3+ regulatory T cells in peripheral blood from children with atopic allergy

Author keywords

Allergy; Children; Flow cytometry; Regulatory T cells

Indexed keywords

CD69 ANTIGEN; CD71 ANTIGEN; IMMUNOGLOBULIN E; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 7 RECEPTOR; MONOCLONAL ANTIBODY; TRANSCRIPTION FACTOR FOXP3;

EID: 84879470120     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000350769     Document Type: Article
Times cited : (69)

References (40)
  • 4
    • 34247271308 scopus 로고    scopus 로고
    • Maintenace of the FoxP3-dependent developmental program in mature regulatory T cells requires contiuned expression of FoxP3
    • Williams LM, Rudensky AY: Maintenace of the FoxP3-dependent developmental program in mature regulatory T cells requires contiuned expression of FoxP3. Nat Immunol 2007; 8: 277-284.
    • (2007) Nat Immunol , vol.8 , pp. 277-284
    • Williams, L.M.1    Rudensky, A.Y.2
  • 6
    • 33847125247 scopus 로고    scopus 로고
    • Regulatory T cell functions are subverted and coverted owing to attenuated FoxP3 expression
    • Wan YY, Flavell RA: Regulatory T cell functions are subverted and coverted owing to attenuated FoxP3 expression. Nature 2007; 45: 766-770.
    • (2007) Nature , vol.45 , pp. 766-770
    • Wan, Y.Y.1    Flavell, R.A.2
  • 7
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY: Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003; 4: 330-336.
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 8
    • 33745813929 scopus 로고    scopus 로고
    • Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
    • Seddiki N, Santner-Nanan B, Martinson J: Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 2006; 203: 1693-1700.
    • (2006) J Exp Med , vol.203 , pp. 1693-1700
    • Seddiki, N.1    Santner-Nanan, B.2    Martinson, J.3
  • 9
    • 33745817085 scopus 로고    scopus 로고
    • CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
    • Liu W, Putnam AL, Xu-yu Z: CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med 2006; 203: 1701-1711.
    • (2006) J Exp Med , vol.203 , pp. 1701-1711
    • Liu, W.1    Putnam, A.L.2    Xu-yu, Z.3
  • 10
    • 84863608598 scopus 로고    scopus 로고
    • Identification, frequency, activation and function of CD4+CD25 high FoxP3+ regulatory T cells in children with juvenile idiopathic arthritis
    • Stelmaszczyk-Emmel A, Jackowska T, Rutkowska- Sak L, Marusak-Banacka M, Wasik M: Identification, frequency, activation and function of CD4+CD25 high FoxP3+ regulatory T cells in children with juvenile idiopathic arthritis. Rheumatol Interantional 2012; 32: 1147-1154.
    • (2012) Rheumatol Interantional , vol.32 , pp. 1147-1154
    • Stelmaszczyk-Emmel, A.1    Jackowska, T.2    Rutkowska- Sak, L.3    Marusak-Banacka, M.4    Wasik, M.5
  • 11
    • 0020961467 scopus 로고
    • Transferrin receptor induction in mitogen-stimulated T lymphocytes is required for DNA synthesis and cell division and is regulated by IL-2
    • Neckers LM, Cossman J: Transferrin receptor induction in mitogen-stimulated T lymphocytes is required for DNA synthesis and cell division and is regulated by IL-2. Proc Natl Acad Sci USA 1983; 80: 3494-3498.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 3494-3498
    • Neckers, L.M.1    Cossman, J.2
  • 12
    • 43949157949 scopus 로고
    • The CD69 receptor: A multipurpose cellsurface trigger for hematopoietic cells
    • Testi R, D'Ambrosini D, De Maria R, Santoni A: The CD69 receptor: A multipurpose cellsurface trigger for hematopoietic cells. Immunol Today 1994; 15: 479-481.
    • (1994) Immunol Today , vol.15 , pp. 479-481
    • Testi, R.1    D'Ambrosini, D.2    De Maria, R.3    Santoni, A.4
  • 13
    • 0036284229 scopus 로고    scopus 로고
    • Characterization of human CD25+ CD4+ T cells in thymus, cord and adult blood
    • Wing K, Ekmark A, Karlsson H, Rudin A, Suri- Payer E: Characterization of human CD25+ CD4+ T cells in thymus, cord and adult blood. Immunology 2002; 106: 190-199.
    • (2002) Immunology , vol.106 , pp. 190-199
    • Wing, K.1    Ekmark, A.2    Karlsson, H.3    Rudin, A.4    Suri- Payer, E.5
  • 14
    • 18144366988 scopus 로고    scopus 로고
    • Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+CD25+ T cells
    • Baecher-Allan C, Wolf E, Hafler DA: Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+CD25+ T cells. Clin Immunol 2005; 115: 10-18.
    • (2005) Clin Immunol , vol.115 , pp. 10-18
    • Baecher-Allan, C.1    Wolf, E.2    Hafler, D.A.3
  • 17
    • 40549093007 scopus 로고    scopus 로고
    • Allergic Rhinitis And Its Impact On Asthma (ARIA) 2008 update
    • Bousquet J, Khaltaev N, Cruz AA, et al: Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update. Allergy 2008; 63(suppl 86):8- 160.
    • (2008) Allergy , vol.63 , Issue.SUPPL. 86 , pp. 8-160
    • Bousquet, J.1    Khaltaev, N.2    Cruz, A.A.3
  • 20
    • 33847624061 scopus 로고    scopus 로고
    • The levels of CD4+CD25+ regulatory T cells in paediatric patients with allergic rhinitis and bronchial asthma
    • Lee J-H, Yu H-H, Wang L-C, Yang Y-H, Lin Y-T, Chiang B-L: The levels of CD4+CD25+ regulatory T cells in paediatric patients with allergic rhinitis and bronchial asthma. Clin Exp Immunol 2007; 148: 53-63.
    • (2007) Clin Exp Immunol , vol.148 , pp. 53-63
    • Lee, J.-H.1    Yu, H.-H.2    Wang, L.-C.3    Yang, Y.-H.4    Lin, Y.-T.5    Chiang, B.-L.6
  • 21
    • 34247842880 scopus 로고    scopus 로고
    • A possible role of CD4+CD25+ T cells as well as transcription factor Foxp3 in the dysregulation of allergic rhinitis
    • Xu G, Mou Z, Jiang H, Cheng L, Shi J, Xu R, Oh Y, Li H: A possible role of CD4+CD25+ T cells as well as transcription factor Foxp3 in the dysregulation of allergic rhinitis. Laryngoscope 2007; 117: 876-880.
    • (2007) Laryngoscope , vol.117 , pp. 876-880
    • Xu, G.1    Mou, Z.2    Jiang, H.3    Cheng, L.4    Shi, J.5    Xu, R.6    Oh, Y.7    Li, H.8
  • 22
    • 39049122818 scopus 로고    scopus 로고
    • Expression of surface markers on peripheral CD4+CD25high T cells in patients with atopic asthma: Role of inhaled corticosteroid
    • Zhang Q, Qian FH, Liu H, Zhou LF, Huang M, Zhang XL, Yin KS: Expression of surface markers on peripheral CD4+CD25high T cells in patients with atopic asthma: Role of inhaled corticosteroid. Chin Med J 2008; 121: 205-212.
    • (2008) Chin Med J , vol.121 , pp. 205-212
    • Zhang, Q.1    Qian, F.H.2    Liu, H.3    Zhou, L.F.4    Huang, M.5    Zhang, X.L.6    Yin, K.S.7
  • 23
    • 2942685507 scopus 로고    scopus 로고
    • Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen- specific T regulatory 1 and T helper 2 cells
    • Adkis M, Verhagen J, Taylor A: Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen- specific T regulatory 1 and T helper 2 cells. J Exp Med 2004; 199: 1567-1575.
    • (2004) J Exp Med , vol.199 , pp. 1567-1575
    • Adkis, M.1    Verhagen, J.2    Taylor, A.3
  • 24
    • 1342308180 scopus 로고    scopus 로고
    • Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T cell activation to atopic status and expression of allergic disease
    • Ling EM, Smith T, Nguyen XD, Pridgeon C, Dallman M, Arbery J, Carr VA, Robinson DS: Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T cell activation to atopic status and expression of allergic disease. Lancet 2004; 363: 608-615.
    • (2004) Lancet , vol.363 , pp. 608-615
    • Ling, E.M.1    Smith, T.2    Nguyen, X.D.3    Pridgeon, C.4    Dallman, M.5    Arbery, J.6    Carr, V.A.7    Robinson, D.S.8
  • 25
    • 4544256262 scopus 로고    scopus 로고
    • Defective suppression of Th2 cytokines by CD4 + CD25 + regulatory T cells in birch allergics during birch pollen season
    • Grindebacke H, Wing K, Andersson AC, Suri- Payer E, Rak S, Rudin A: Defective suppression of Th2 cytokines by CD4 + CD25 + regulatory T cells in birch allergics during birch pollen season. Clin Exp Allergy 2004; 34: 1364-1372.
    • (2004) Clin Exp Allergy , vol.34 , pp. 1364-1372
    • Grindebacke, H.1    Wing, K.2    Andersson, A.C.3    Suri- Payer, E.4    Rak, S.5    Rudin, A.6
  • 27
    • 20844432359 scopus 로고    scopus 로고
    • Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma
    • Karagiannidis C, Akdis M, Holopainen P: Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma. J Allergy Clin Immunol 2004; 114: 1425-1433.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 1425-1433
    • Karagiannidis, C.1    Akdis, M.2    Holopainen, P.3
  • 28
    • 4644227859 scopus 로고    scopus 로고
    • Regulatory CD4+CD25+ T lymphocytes in peripheral blood from patients with atopic asthma
    • Shi HZ, Li S, Xie ZF, Qin XJ, Qin X, Zhong XN: Regulatory CD4+CD25+ T lymphocytes in peripheral blood from patients with atopic asthma. Clin Immunol 2004; 113: 172- 178.
    • (2004) Clin Immunol , vol.113 , pp. 172-178
    • Shi, H.Z.1    Li, S.2    Xie, Z.F.3    Qin, X.J.4    Qin, X.5    Zhong, X.N.6
  • 29
    • 0035495857 scopus 로고    scopus 로고
    • The germless theory of allergic disease: Revisiting the hygiene hypothesis
    • Wills-Karp M, Santeliz J, Karp CL: The germless theory of allergic disease: Revisiting the hygiene hypothesis. Nat Rev Immunol 2001; 1: 69-75.
    • (2001) Nat Rev Immunol , vol.1 , pp. 69-75
    • Wills-Karp, M.1    Santeliz, J.2    Karp, C.L.3
  • 30
    • 33646487278 scopus 로고    scopus 로고
    • Tolllike receptor 2 signaling modulates the functions of CD4 + CD25 + regulatory T cells
    • Liu H, Komai-Koma M, Xu D, Liew FY: Tolllike receptor 2 signaling modulates the functions of CD4 + CD25 + regulatory T cells. Proc Natl Acad Sci USA 2006; 103: 7048-7053.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7048-7053
    • Liu, H.1    Komai-Koma, M.2    Xu, D.3    Liew, F.Y.4
  • 31
    • 58149306013 scopus 로고    scopus 로고
    • In vivo switch to IL- 10-secreting T regulatory cells in high dose allergen exposure
    • Meiler F, Zumkehr J, Klunker S, Ruckert B, Akdis CA, Akdis M: In vivo switch to IL- 10-secreting T regulatory cells in high dose allergen exposure. J Exp Med 2008; 205: 2887- 2898.
    • (2008) J Exp Med , vol.205 , pp. 2887-2898
    • Meiler, F.1    Zumkehr, J.2    Klunker, S.3    Ruckert, B.4    Akdis, C.A.5    Akdis, M.6
  • 32
    • 17644384896 scopus 로고    scopus 로고
    • CD4+ CD25+ T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis
    • Mottonen M, Heikkinen J, Mustonen L, Isomaki P, Luukkainen R, Lassila O: CD4+ CD25+ T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis. Clin Exp Immunol 2005; 140: 360-367.
    • (2005) Clin Exp Immunol , vol.140 , pp. 360-367
    • Mottonen, M.1    Heikkinen, J.2    Mustonen, L.3    Isomaki, P.4    Luukkainen, R.5    Lassila, O.6
  • 33
    • 0037261145 scopus 로고    scopus 로고
    • Isolation and functional characterization of regulatory CD25 bright CD4 + T cells from the target organ of patients with rheumatoid arthritis
    • Cao D, Malmstrom V, Beacher-Allan C, Hafler D, Klareskog L, Trollmo C: Isolation and functional characterization of regulatory CD25 bright CD4 + T cells from the target organ of patients with rheumatoid arthritis. Eur J Immunol 2003; 33: 215-223.
    • (2003) Eur J Immunol , vol.33 , pp. 215-223
    • Cao, D.1    Malmstrom, V.2    Beacher-Allan, C.3    Hafler, D.4    Klareskog, L.5    Trollmo, C.6
  • 34
    • 63449138003 scopus 로고    scopus 로고
    • Selective deregulation in chemokine signaling pathways of CD4 + CD25 hi CD127 lo / - regulatory T cells in human allergic asthma
    • Nguyen KD, Vanichsarn C, Fohner A, Nadeau KC: Selective deregulation in chemokine signaling pathways of CD4 + CD25 hi CD127 lo / - regulatory T cells in human allergic asthma. J Allergy Clin Immunol 2009; 123: 933-939.
    • (2009) J Allergy Clin Immunol , vol.123 , pp. 933-939
    • Nguyen, K.D.1    Vanichsarn, C.2    Fohner, A.3    Nadeau, K.C.4
  • 35
    • 54049137604 scopus 로고    scopus 로고
    • XCL1 enhances regulatory activities of CD4 + CD25 high CD- 127 low/- T cells in human allergic asthma
    • Nguyen KD, Fohner A, Booker JD, Dong C, Krensky AM, Nadeau KC: XCL1 enhances regulatory activities of CD4 + CD25 high CD- 127 low/- T cells in human allergic asthma. J Immunol 2008; 181: 5386-5395.
    • (2008) J Immunol , vol.181 , pp. 5386-5395
    • Nguyen, K.D.1    Fohner, A.2    Booker, J.D.3    Dong, C.4    Krensky, A.M.5    Nadeau, K.C.6
  • 38
  • 39
    • 53749096798 scopus 로고    scopus 로고
    • Distinct regulation of IgE, IgG4 and IgA by T regulatory cells and toll-like receptors
    • Meiler F, Klunker S, Zimmermann M, Akdis CA, Akdis M: Distinct regulation of IgE, IgG4 and IgA by T regulatory cells and toll-like receptors. Allergy 2008; 63: 1455-1463.
    • (2008) Allergy , vol.63 , pp. 1455-1463
    • Meiler, F.1    Klunker, S.2    Zimmermann, M.3    Akdis, C.A.4    Akdis, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.