-
1
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling: cell fate control and signal integration in development. Science 1999;284: 770-6.
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
2
-
-
7244250027
-
Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis
-
Pece S, Serresi M, Santolini E, Capra M, Hulleman E, Galimberti V, et al. Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis. J Cell Biol 2004;167:215-21.
-
(2004)
J Cell Biol
, vol.167
, pp. 215-221
-
-
Pece, S.1
Serresi, M.2
Santolini, E.3
Capra, M.4
Hulleman, E.5
Galimberti, V.6
-
3
-
-
24944506696
-
High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival
-
Reedijk M, Odorcic S, Chang L, Zhang H, Miller N, McCready DR, et al. High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival. Cancer Res 2005;65:8530-7.
-
(2005)
Cancer Res
, vol.65
, pp. 8530-8537
-
-
Reedijk, M.1
Odorcic, S.2
Chang, L.3
Zhang, H.4
Miller, N.5
McCready, D.R.6
-
4
-
-
32944470488
-
Aberrant activation of notch signaling in human breast cancer
-
Stylianou S, Clarke RB, Brennan K. Aberrant activation of notch signaling in human breast cancer. Cancer Res 2006;66:1517-25.
-
(2006)
Cancer Res
, vol.66
, pp. 1517-1525
-
-
Stylianou, S.1
Clarke, R.B.2
Brennan, K.3
-
5
-
-
48549103124
-
Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches
-
Rizzo P, Miao H, D'Souza G, Osipo C, Song LL, Yun J, et al. Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches. Cancer Res 2008;68:5226-35.
-
(2008)
Cancer Res
, vol.68
, pp. 5226-5235
-
-
Rizzo, P.1
Miao, H.2
D'Souza, G.3
Osipo, C.4
Song, L.L.5
Yun, J.6
-
6
-
-
0033613401
-
Involvement of Notch1 in the development of mouse mammary tumors
-
Dievart A, Beaulieu N, Jolicoeur P. Involvement of Notch1 in the development of mouse mammary tumors. Oncogene 1999;18: 5973-81.
-
(1999)
Oncogene
, vol.18
, pp. 5973-5981
-
-
Dievart, A.1
Beaulieu, N.2
Jolicoeur, P.3
-
7
-
-
38549148417
-
Notch and cancer: A double-edged sword
-
Koch U, Radtke F. Notch and cancer: a double-edged sword. Cell Mol Life Sci 2007;64:2746-62.
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 2746-2762
-
-
Koch, U.1
Radtke, F.2
-
9
-
-
34648857551
-
Notch emerges as new cancer drug target
-
Garber K. Notch emerges as new cancer drug target. J Natl Cancer Inst 2007;99:1284-5.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 1284-1285
-
-
Garber, K.1
-
10
-
-
0030659821
-
Sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins
-
Hubbard EJ, Wu G, Kitajewski J, Greenwald I. sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins. Genes Dev 1997;11:3182-93.
-
(1997)
Genes Dev
, vol.11
, pp. 3182-3193
-
-
Hubbard, E.J.1
Wu, G.2
Kitajewski, J.3
Greenwald, I.4
-
11
-
-
0035860804
-
Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor
-
Gupta-Rossi N, Le Bail O, GonenH, BrouC, Logeat F, Six E, et al. Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor. J Biol Chem 2001;276:34371-8.
-
(2001)
J Biol Chem
, vol.276
, pp. 34371-34378
-
-
Gupta-Rossi, N.1
Le Bail, O.2
Gonen, H.3
Brou, C.4
Logeat, F.5
Six, E.6
-
12
-
-
34547780475
-
FBW7mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors
-
O'Neil J, Grim J, Strack P, Rao S, Tibbitts D, Winter C, et al.FBW7mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors. J Exp Med 2007;204:1813-24.
-
(2007)
J Exp Med
, vol.204
, pp. 1813-1824
-
-
O'Neil, J.1
Grim, J.2
Strack, P.3
Rao, S.4
Tibbitts, D.5
Winter, C.6
-
13
-
-
34547820257
-
The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia
-
Thompson BJ, Buonamici S, Sulis ML, Palomero T, Vilimas T, Basso G, et al. The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia. J Exp Med 2007;204:1825-35.
-
(2007)
J Exp Med
, vol.204
, pp. 1825-1835
-
-
Thompson, B.J.1
Buonamici, S.2
Sulis, M.L.3
Palomero, T.4
Vilimas, T.5
Basso, G.6
-
15
-
-
79251474710
-
Inhibition of Notch1 signaling by Runx2 during osteoblast differentiation
-
Ann EJ, Kim HY, Choi YH, Kim MY, MoJS, Jung J, et al. Inhibition of Notch1 signaling by Runx2 during osteoblast differentiation. J Bone Miner Res 2011;26:317-30.
-
(2011)
J Bone Miner Res
, vol.26
, pp. 317-330
-
-
Ann, E.J.1
Kim, H.Y.2
Choi, Y.H.3
Kim, M.Y.4
Mo, J.S.5
Jung, J.6
-
16
-
-
78651104178
-
Serum-and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase
-
Mo JS, Ann EJ, Yoon JH, Jung J, Choi YH, Kim HY, et al. Serum-and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase. J Cell Sci 2011;124:100-12.
-
(2011)
J Cell Sci
, vol.124
, pp. 100-112
-
-
Mo, J.S.1
Ann, E.J.2
Yoon, J.H.3
Jung, J.4
Choi, Y.H.5
Kim, H.Y.6
-
17
-
-
41949130508
-
Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1
-
Choi DW, Seo YM, Kim EA, Sung KS, Ahn JW, Park SJ, et al. Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1. J Biol Chem 2008;283:4682-9.
-
(2008)
J Biol Chem
, vol.283
, pp. 4682-4689
-
-
Choi, D.W.1
Seo, Y.M.2
Kim, E.A.3
Sung, K.S.4
Ahn, J.W.5
Park, S.J.6
-
18
-
-
38549086019
-
FBW7 ubiquitin ligase: A tumour suppressor at the crossroads of cell division, growth and differentiation
-
Welcker M, Clurman BE. FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. Nat Rev Cancer 2008;8:83-93.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 83-93
-
-
Welcker, M.1
Clurman, B.E.2
-
19
-
-
67650447715
-
The human protein kinase HIPK2 phosphorylates and downregulates the methyl-binding transcription factor ZBTB4
-
Yamada D, Perez-Torrado R, Filion G, Caly M, Jammart B, Devignot V, et al. The human protein kinase HIPK2 phosphorylates and downregulates the methyl-binding transcription factor ZBTB4. Oncogene 2009;28:2535-44.
-
(2009)
Oncogene
, vol.28
, pp. 2535-2544
-
-
Yamada, D.1
Perez-Torrado, R.2
Filion, G.3
Caly, M.4
Jammart, B.5
Devignot, V.6
-
20
-
-
34548740091
-
HIPK2 represses betacatenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis
-
Wei G, Ku S, Ma GK, Saito S, Tang AA, Zhang J, et al. HIPK2 represses betacatenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis. Proc Natl Acad Sci U S A 2007;104:13040-5.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 13040-13045
-
-
Wei, G.1
Ku, S.2
Ma, G.K.3
Saito, S.4
Tang, A.A.5
Zhang, J.6
-
21
-
-
78651330430
-
COSMIC: Mining complete cancer genomes in the catalogue of somatic mutations in cancer
-
Forbes SA, Bindal N, Bamford S, Cole C, Kok CY, Beare D, et al. COSMIC: mining complete cancer genomes in the catalogue of somatic mutations in cancer. Nucleic Acids Res 2011;39(Database issue): D945-50.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. D945-D950
-
-
Forbes, S.A.1
Bindal, N.2
Bamford, S.3
Cole, C.4
Kok, C.Y.5
Beare, D.6
-
22
-
-
68749088356
-
NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia
-
Real PJ, Ferrando AA. NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia. Leukemia 2009;23:1374-7.
-
(2009)
Leukemia
, vol.23
, pp. 1374-1377
-
-
Real, P.J.1
Ferrando, A.A.2
-
23
-
-
33645049305
-
Downregulation of notch-1 inhibits invasion by inactivation of nuclear factorkappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells
-
Wang Z, Banerjee S, Li Y, Rahman KM, Zhang Y, Sarkar FH. Downregulation of notch-1 inhibits invasion by inactivation of nuclear factorkappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells. Cancer Res 2006;66:2778-84.
-
(2006)
Cancer Res
, vol.66
, pp. 2778-2784
-
-
Wang, Z.1
Banerjee, S.2
Li, Y.3
Rahman, K.M.4
Zhang, Y.5
Sarkar, F.H.6
-
24
-
-
34948910811
-
HIPK2: A multitalented partner for transcription factors in DNA damage response and development
-
Rinaldo C, Prodosmo A, Siepi F, Soddu S. HIPK2: a multitalented partner for transcription factors in DNA damage response and development. Biochem Cell Biol 2007;85:411-8.
-
(2007)
Biochem Cell Biol
, vol.85
, pp. 411-418
-
-
Rinaldo, C.1
Prodosmo, A.2
Siepi, F.3
Soddu, S.4
-
25
-
-
18244379872
-
Homeodomain-interacting protein kinase-2 phosphorylates p53 at ser 46 and mediates apoptosis
-
D'Orazi G, Cecchinelli B, Bruno T, Manni I, Higashimoto Y, Saito S, et al. Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis. Nat Cell Biol 2002;4:11-9.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 11-19
-
-
D'Orazi, G.1
Cecchinelli, B.2
Bruno, T.3
Manni, I.4
Higashimoto, Y.5
Saito, S.6
-
26
-
-
0036141392
-
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2
-
Hofmann TG, Moller A, Sirma H, Zentgraf H, Taya Y, Droge W, et al. Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2. Nat Cell Biol 2002;4:1-10.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 1-10
-
-
Hofmann, T.G.1
Moller, A.2
Sirma, H.3
Zentgraf, H.4
Taya, Y.5
Droge, W.6
-
27
-
-
33947273628
-
Homeodomain-interacting protein kinase 2 is the ionizing radiation-activated p53 serine 46 kinase and is regulated by ATM
-
Dauth I, Kruger J, Hofmann TG. Homeodomain-interacting protein kinase 2 is the ionizing radiation-activated p53 serine 46 kinase and is regulated by ATM. Cancer Res 2007;67:2274-9.
-
(2007)
Cancer Res
, vol.67
, pp. 2274-2279
-
-
Dauth, I.1
Kruger, J.2
Hofmann, T.G.3
-
28
-
-
5044225888
-
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
-
Weng AP, Ferrando AA, Lee W, Morris JPt, Silverman LB, Sanchez-Irizarry C, et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 2004;306:269-71.
-
(2004)
Science
, vol.306
, pp. 269-271
-
-
Weng, A.P.1
Ferrando, A.A.2
Lee, W.3
Morris, J.Pt.4
Silverman, L.B.5
Sanchez-Irizarry, C.6
-
30
-
-
84908489045
-
Cyclin C is a haploinsufficient tumour suppressor
-
Li N, Fassl A, Chick J, Inuzuka H, Li X, Mansour MR, et al. Cyclin C is a haploinsufficient tumour suppressor. Nat Cell Biol 2014;16:1080-91.
-
(2014)
Nat Cell Biol
, vol.16
, pp. 1080-1091
-
-
Li, N.1
Fassl, A.2
Chick, J.3
Inuzuka, H.4
Li, X.5
Mansour, M.R.6
-
31
-
-
0035929669
-
The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog
-
Oberg C, Li J, Pauley A, Wolf E, Gurney M, Lendahl U. The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog. J Biol Chem 2001;276:35847-53.
-
(2001)
J Biol Chem
, vol.276
, pp. 35847-35853
-
-
Oberg, C.1
Li, J.2
Pauley, A.3
Wolf, E.4
Gurney, M.5
Lendahl, U.6
-
32
-
-
0034791336
-
SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation
-
WuG, Lyapina S, Das I, Li J, Gurney M, Pauley A, et al. SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation. Mol Cell Biol 2001;21:7403-15.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7403-7415
-
-
Wu, G.1
Lyapina, S.2
Das, I.3
Li, J.4
Gurney, M.5
Pauley, A.6
|