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Volumn 6, Issue 2, 2016, Pages 440-451

IL-17 induces EMT via Stat3 in lung adenocarcinoma

Author keywords

IL 17; Lung adenocarcinoma; Snail1; Snail2; Stat3; Twist1

Indexed keywords

INTERLEUKIN 17; NERVE CELL ADHESION MOLECULE; SMALL INTERFERING RNA; STAT3 PROTEIN; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR SNAIL1; TRANSCRIPTION FACTOR SNAIL2; TRANSCRIPTION FACTOR TWIST; TRANSCRIPTION FACTOR TWIST1; UNCLASSIFIED DRUG; VIMENTIN;

EID: 84981763409     PISSN: None     EISSN: 21566976     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (44)

References (40)
  • 4
    • 84934436008 scopus 로고    scopus 로고
    • A personalized treatment for lung cancer: molecular pathways, targeted therapies, and genomic characterization
    • Hensing T, Chawla A, Batra R, Salgia R. A personalized treatment for lung cancer: molecular pathways, targeted therapies, and genomic characterization. Adv Exp Med Biol 2014; 799: 85-117.
    • (2014) Adv Exp Med Biol , vol.799 , pp. 85-117
    • Hensing, T.1    Chawla, A.2    Batra, R.3    Salgia, R.4
  • 5
    • 84896737116 scopus 로고    scopus 로고
    • The role of the tumor-microenvironment in lung cancer-metastasis and its relationship to potential therapeutic targets
    • Wood SL, Pernemalm M, Crosbie PA, Whetton AD. The role of the tumor-microenvironment in lung cancer-metastasis and its relationship to potential therapeutic targets. Cancer Treat Rev 2014; 40: 558-66.
    • (2014) Cancer Treat Rev , vol.40 , pp. 558-566
    • Wood, S.L.1    Pernemalm, M.2    Crosbie, P.A.3    Whetton, A.D.4
  • 6
    • 58149335431 scopus 로고    scopus 로고
    • Prognostic significance of epithelialmesenchymal and mesenchymal-epithelial transition protein expression in non-small cell lung cancer
    • Soltermann A, Tischler V, Arbogast S, Braun J, Probst-Hensch N, Weder W, Moch H, Kristiansen G. Prognostic significance of epithelialmesenchymal and mesenchymal-epithelial transition protein expression in non-small cell lung cancer. Clin Cancer Res 2008; 14: 7430-7.
    • (2008) Clin Cancer Res , vol.14 , pp. 7430-7437
    • Soltermann, A.1    Tischler, V.2    Arbogast, S.3    Braun, J.4    Probst-Hensch, N.5    Weder, W.6    Moch, H.7    Kristiansen, G.8
  • 8
    • 43049157905 scopus 로고    scopus 로고
    • Inflammation in the development of lung cancer: epidemiological evidence
    • Engels EA. Inflammation in the development of lung cancer: epidemiological evidence. Expert Rev Anticancer Ther 2008; 8: 605-15.
    • (2008) Expert Rev Anticancer Ther , vol.8 , pp. 605-615
    • Engels, E.A.1
  • 11
    • 70449715722 scopus 로고    scopus 로고
    • Protumor vs antitumor functions of IL-17
    • Murugaiyan G, Saha B. Protumor vs antitumor functions of IL-17. J Immunol 2009; 183: 4169-75.
    • (2009) J Immunol , vol.183 , pp. 4169-4175
    • Murugaiyan, G.1    Saha, B.2
  • 12
    • 84869861913 scopus 로고    scopus 로고
    • The emerging role of T cell cytokines in non-small cell lung cancer
    • Neurath MF, Finotto S. The emerging role of T cell cytokines in non-small cell lung cancer. Cytokine Growth Factor Rev 2012; 23: 315-22.
    • (2012) Cytokine Growth Factor Rev , vol.23 , pp. 315-322
    • Neurath, M.F.1    Finotto, S.2
  • 13
    • 84869868598 scopus 로고    scopus 로고
    • IL-17A is a central regulator of lung tumor growth
    • Reppert S, Koch S, Finotto S. IL-17A is a central regulator of lung tumor growth. Oncoimmunology 2012; 1: 783-785.
    • (2012) Oncoimmunology , vol.1 , pp. 783-785
    • Reppert, S.1    Koch, S.2    Finotto, S.3
  • 17
    • 80053070208 scopus 로고    scopus 로고
    • Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-beta1-dependent and-independent mechanisms
    • Mi S, Li Z, Yang HZ, Liu H, Wang JP, Ma YG, Wang XX, Liu HZ, Sun W, Hu ZW. Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-beta1-dependent and-independent mechanisms. J Immunol 2011; 187: 3003-14.
    • (2011) J Immunol , vol.187 , pp. 3003-3014
    • Mi, S.1    Li, Z.2    Yang, H.Z.3    Liu, H.4    Wang, J.P.5    Ma, Y.G.6    Wang, X.X.7    Liu, H.Z.8    Sun, W.9    Hu, Z.W.10
  • 18
    • 80053300494 scopus 로고    scopus 로고
    • How the genetics of lung cancer may overlap with COPD
    • Young RP, Hopkins RJ. How the genetics of lung cancer may overlap with COPD. Respirology 2011; 16: 1047-55.
    • (2011) Respirology , vol.16 , pp. 1047-1055
    • Young, R.P.1    Hopkins, R.J.2
  • 20
    • 84916899060 scopus 로고    scopus 로고
    • IL-17/miR-192/IL-17Rs regulatory feedback loop facilitates multiple myeloma progression
    • Sun Y, Pan J, Mao S, Jin J. IL-17/miR-192/IL-17Rs regulatory feedback loop facilitates multiple myeloma progression. PLoS One 2014; 9: e114647.
    • (2014) PLoS One , vol.9
    • Sun, Y.1    Pan, J.2    Mao, S.3    Jin, J.4
  • 22
    • 77955095712 scopus 로고    scopus 로고
    • Increased IL-17-producing cells correlate with poor survival and lymphangiogenesis in NSCLC patients
    • Chen X, Wan J, Liu J, Xie W, Diao X, Xu J, Zhu B, Chen Z. Increased IL-17-producing cells correlate with poor survival and lymphangiogenesis in NSCLC patients. Lung Cancer 2010; 69: 348-54.
    • (2010) Lung Cancer , vol.69 , pp. 348-354
    • Chen, X.1    Wan, J.2    Liu, J.3    Xie, W.4    Diao, X.5    Xu, J.6    Zhu, B.7    Chen, Z.8
  • 23
    • 77958601145 scopus 로고    scopus 로고
    • Role of interleukin-17 in lymphangiogenesis in non-small-cell lung cancer: Enhanced production of vascular endothelial growth factor C in non-small-cell lung carcinoma cells
    • Chen X, Xie Q, Cheng X, Diao X, Cheng Y, Liu J, Xie W, Chen Z, Zhu B. Role of interleukin-17 in lymphangiogenesis in non-small-cell lung cancer: Enhanced production of vascular endothelial growth factor C in non-small-cell lung carcinoma cells. Cancer Sci 2010; 101: 2384-90.
    • (2010) Cancer Sci , vol.101 , pp. 2384-2390
    • Chen, X.1    Xie, Q.2    Cheng, X.3    Diao, X.4    Cheng, Y.5    Liu, J.6    Xie, W.7    Chen, Z.8    Zhu, B.9
  • 24
    • 84869845842 scopus 로고    scopus 로고
    • IL-17 promoted metastasis of non-small-cell lung cancer cells
    • Li Q, Han Y, Fei G, Guo Z, Ren T, Liu Z. IL-17 promoted metastasis of non-small-cell lung cancer cells. Immunol. Immunol Lett 2012; 148: 144-50.
    • (2012) Immunol. Immunol Lett , vol.148 , pp. 144-150
    • Li, Q.1    Han, Y.2    Fei, G.3    Guo, Z.4    Ren, T.5    Liu, Z.6
  • 26
    • 78650636066 scopus 로고    scopus 로고
    • Generation and differentiation of IL-17-producing CD4+ T cells in malignant pleural effusion
    • Ye ZJ, Zhou Q, Gu YY, Qin SM, Ma WL, Xin JB, Tao XN, Shi HZ. Generation and differentiation of IL-17-producing CD4+ T cells in malignant pleural effusion. J Immunol 2010; 185: 6348-54.
    • (2010) J Immunol , vol.185 , pp. 6348-6354
    • Ye, Z.J.1    Zhou, Q.2    Gu, Y.Y.3    Qin, S.M.4    Ma, W.L.5    Xin, J.B.6    Tao, X.N.7    Shi, H.Z.8
  • 29
    • 84943600630 scopus 로고    scopus 로고
    • Interleukin-17-induced EMT promotes lung cancer cell migration and invasion via NF-kappaB/ ZEB1 signal pathway
    • Gu K, Li MM, Shen J, Liu F, Cao JY, Jin S, Yu Y. Interleukin-17-induced EMT promotes lung cancer cell migration and invasion via NF-kappaB/ ZEB1 signal pathway. Am J Cancer Res 2015; 5: 1169-79.
    • (2015) Am J Cancer Res , vol.5 , pp. 1169-1179
    • Gu, K.1    Li, M.M.2    Shen, J.3    Liu, F.4    Cao, J.Y.5    Jin, S.6    Yu, Y.7
  • 30
    • 79954414473 scopus 로고    scopus 로고
    • Signaling of interleukin-17 family cytokines in immunity and inflammation
    • Chang SH, Dong C. Signaling of interleukin-17 family cytokines in immunity and inflammation. Cell Signal 2011; 2: 1069-75.
    • (2011) Cell Signal , vol.2 , pp. 1069-1075
    • Chang, S.H.1    Dong, C.2
  • 31
    • 84899051828 scopus 로고    scopus 로고
    • JAK/STAT3 signaling is required for TGF-beta-induced epithelial-mesenchymal transition in lung cancer cells
    • Liu RY, Zeng Y, Lei Z, Wang L, Yang H, Liu Z, Zhao J, Zhang HT. JAK/STAT3 signaling is required for TGF-beta-induced epithelial-mesenchymal transition in lung cancer cells. Int J Oncol 2014; 44: 1643-51.
    • (2014) Int J Oncol , vol.44 , pp. 1643-1651
    • Liu, R.Y.1    Zeng, Y.2    Lei, Z.3    Wang, L.4    Yang, H.5    Liu, Z.6    Zhao, J.7    Zhang, H.T.8
  • 32
    • 84901036169 scopus 로고    scopus 로고
    • Metformin sensitizes EGFR-TKI-resistant human lung cancer cells in vitro and in vivo through inhibition of IL-6 signaling and EMT reversal
    • Li L, Han R, Xiao H, Lin C, Wang Y, Liu H, Li K, Chen H, Sun F, Yang Z, Jiang J, He Y. Metformin sensitizes EGFR-TKI-resistant human lung cancer cells in vitro and in vivo through inhibition of IL-6 signaling and EMT reversal. Clin Cancer Res 2014; 20: 2714-26.
    • (2014) Clin Cancer Res , vol.20 , pp. 2714-2726
    • Li, L.1    Han, R.2    Xiao, H.3    Lin, C.4    Wang, Y.5    Liu, H.6    Li, K.7    Chen, H.8    Sun, F.9    Yang, Z.10    Jiang, J.11    He, Y.12
  • 33
    • 84922395039 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition inducing transcription factors and metastatic cancer
    • Tania M, Khan MA, Fu J. Epithelial to mesenchymal transition inducing transcription factors and metastatic cancer. Tumour Biol 2014; 35: 7335-42.
    • (2014) Tumour Biol , vol.35 , pp. 7335-7342
    • Tania, M.1    Khan, M.A.2    Fu, J.3
  • 34
    • 80052403945 scopus 로고    scopus 로고
    • The EMT regulator slug and lung carcinogenesis
    • Shih JY, Yang PC. The EMT regulator slug and lung carcinogenesis. Carcinogenesis 2011; 32: 1299-304.
    • (2011) Carcinogenesis , vol.32 , pp. 1299-1304
    • Shih, J.Y.1    Yang, P.C.2
  • 35
    • 84866652772 scopus 로고    scopus 로고
    • Hasegawa, Emerging evidence of epithelial-to-mesenchymal transition in lung carcinogenesis
    • Sato M, Shames DS, Hasegawa Y. Hasegawa, Emerging evidence of epithelial-to-mesenchymal transition in lung carcinogenesis. Respirology 2012; 17: 1048-59.
    • (2012) Respirology , vol.17 , pp. 1048-1059
    • Sato, M.1    Shames, D.S.2    Hasegawa, Y.3
  • 36
    • 84931562777 scopus 로고    scopus 로고
    • Wogonin suppresses human alveolar adenocarcinoma cell A549 migration in inflammatory microenvironment by modulating the IL-6/STAT3 signaling pathway
    • Zhao Y, Yao J, Wu XP, Zhao L, Zhou YX, Zhang Y, You QD, Guo QL, Lu N. Wogonin suppresses human alveolar adenocarcinoma cell A549 migration in inflammatory microenvironment by modulating the IL-6/STAT3 signaling pathway. Mol Carcinog 2015; 54 Suppl 1: E81-93.
    • (2015) Mol Carcinog , vol.54 , pp. E81-E93
    • Zhao, Y.1    Yao, J.2    Wu, X.P.3    Zhao, L.4    Zhou, Y.X.5    Zhang, Y.6    You, Q.D.7    Guo, Q.L.8    Lu, N.9
  • 37
    • 84925483834 scopus 로고    scopus 로고
    • The CCL2/CCR2 axis enhances IL-6-induced epithelial-mesenchymal transition by cooperatively activating STAT3-Twist signaling
    • Chen W, Gao Q, Han S, Pan F, Fan W. The CCL2/CCR2 axis enhances IL-6-induced epithelial-mesenchymal transition by cooperatively activating STAT3-Twist signaling. Tumour Biol 2015; 36: 973-81.
    • (2015) Tumour Biol , vol.36 , pp. 973-981
    • Chen, W.1    Gao, Q.2    Han, S.3    Pan, F.4    Fan, W.5
  • 38
    • 84899733576 scopus 로고    scopus 로고
    • Metformin inhibits the IL-6-induced epithelial-mesenchymal transition and lung adenocarcinoma growth and metastasis
    • Zhao Z, Cheng X, Wang Y, Han R, Li L, Xiang T, He L, Long H, Zhu B, He Y. Metformin inhibits the IL-6-induced epithelial-mesenchymal transition and lung adenocarcinoma growth and metastasis. PLoS One 2014; 9: e95884.
    • (2014) PLoS One , vol.9
    • Zhao, Z.1    Cheng, X.2    Wang, Y.3    Han, R.4    Li, L.5    Xiang, T.6    He, L.7    Long, H.8    Zhu, B.9    He, Y.10
  • 39
    • 84944878827 scopus 로고    scopus 로고
    • Paeonol inhibits B16F10 melanoma metastasis In vitro and In Vivo via disrupting proinflammatory cytokines-mediated NF-kappaB and STAT3 pathways
    • Zhang L, Tao L, Shi T, Zhang F, Sheng X, Cao Y, Zheng S, Wang A, Qian W, Jiang L, Lu Y. Paeonol inhibits B16F10 melanoma metastasis In vitro and In Vivo via disrupting proinflammatory cytokines-mediated NF-kappaB and STAT3 pathways. IUBMB Life 2015; 67: 778-88.
    • (2015) IUBMB Life , vol.67 , pp. 778-788
    • Zhang, L.1    Tao, L.2    Shi, T.3    Zhang, F.4    Sheng, X.5    Cao, Y.6    Zheng, S.7    Wang, A.8    Qian, W.9    Jiang, L.10    Lu, Y.11
  • 40
    • 84904746763 scopus 로고    scopus 로고
    • Lung carcinogenesis from chronic obstructive pulmonary disease: characteristics of lung cancer from COPD and contribution of signal transducers and lung stem cells in the inflammatory microenvironment
    • Sekine Y, Hata A, Koh E, Hiroshima K. Lung carcinogenesis from chronic obstructive pulmonary disease: characteristics of lung cancer from COPD and contribution of signal transducers and lung stem cells in the inflammatory microenvironment. Gen Thorac Cardiovasc Surg 2014; 62: 415-21.
    • (2014) Gen Thorac Cardiovasc Surg , vol.62 , pp. 415-421
    • Sekine, Y.1    Hata, A.2    Koh, E.3    Hiroshima, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.