Paeonol inhibits B16F10 melanoma metastasis In vitro and In Vivo via disrupting proinflammatory cytokines-mediated NF-κB and STAT3 pathways

IUBMB Life

Volumn 67, Issue 10, 2015, Pages 778-788

  Zhang, Lei ^a,b   Tao, Li ^a   Shi, Tianlu ^b   Zhang, Feng ^a   Sheng, Xiaobo ^a   Cao, Yuzhu ^a   Zheng, Shizhong ^a   Wang, Aiyun ^a   Qian, Wenhui ^c   Jiang, Ling ^b   Lu, Yin ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

^c NANJING GENERAL HOSPITAL OF NANJING MILITARY COMMAND   (China)

Author keywords

B16F10 mouse melanoma; cell invasion; cell migration; NF B; paeonol; STAT3

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MATRIX METALLOPROTEINASE; PEONOL; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; ACETOPHENONE DERIVATIVE; ANTINEOPLASTIC AGENT; STAT3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BLOOD LEVEL; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE RELEASE; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUCIFERASE ASSAY; LUNG METASTASIS; MELANOMA CELL; MELANOMA METASTASIS; METASTASIS INHIBITION; MOUSE; MTS ASSAY; NONHUMAN; PHENOTYPE; PROMOTER REGION; PROTEIN BINDING; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CELL MOTION; DRUG SCREENING; LUNG NEOPLASMS; MELANOMA, EXPERIMENTAL; METABOLISM; PATHOLOGY; SECONDARY; SKIN NEOPLASMS; TUMOR CELL LINE; TUMOR INVASION;

ACETOPHENONES; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; CELL MOVEMENT; CYTOKINES; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; LUNG NEOPLASMS; MELANOMA, EXPERIMENTAL; MICE, INBRED C57BL; NEOPLASM INVASIVENESS; NF-KAPPA B; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; STAT3 TRANSCRIPTION FACTOR;

EID: 84944878827     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.1435     Document Type: Article

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