-
1
-
-
69249133245
-
Deciphering the impact of common genetic variation on lung cancer risk: A genome-wide association study
-
Broderick P, Wang Y, Vijayakarishnan V, et al,. Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study. Cancer Res. 2009; 69: 6633-41.
-
(2009)
Cancer Res.
, vol.69
, pp. 6633-6641
-
-
Broderick, P.1
Wang, Y.2
Vijayakarishnan, V.3
-
2
-
-
2442628171
-
Genetics of COPD
-
DOI 10.1378/chest.125.5.1929
-
Molfino NA,. Genetics of COPD. Chest 2004; 125: 1929-40. (Pubitemid 38648430)
-
(2004)
Chest
, vol.125
, Issue.5
, pp. 1929-1940
-
-
Molfino, N.A.1
-
3
-
-
0035169529
-
A short history of lung cancer
-
Witschi H,. A short history of lung cancer. Toxicol Sci. 2001; 64: 4-6. (Pubitemid 33062181)
-
(2001)
Toxicological Sciences
, vol.64
, Issue.1
, pp. 4-6
-
-
Witschi, H.1
-
4
-
-
80053322155
-
-
National Cancer Institute [Accessed 25 July 2011.] Available from URL
-
National Cancer Institute. SEER Statistics and Facts. [Accessed 25 July 2011.] Available from URL
-
SEER Statistics and Facts
-
-
-
5
-
-
34548267728
-
International variation in the prevalence of COPD (The BOLD Study): A population-based prevalence study
-
DOI 10.1016/S0140-6736(07)61377-4, PII S0140673607613774
-
Buist AS, McBurnie MA, Vollmer WM, et al,. International variation in the prevalence of COPD (the BOLD Study): a population based prevalence study. Lancet 2007; 370: 741-50. (Pubitemid 47321907)
-
(2007)
Lancet
, vol.370
, Issue.9589
, pp. 741-750
-
-
Buist, A.S.1
McBurnie, M.A.2
Vollmer, W.M.3
Gillespie, S.4
Burney, P.5
Mannino, D.M.6
Menezes, A.M.7
Sullivan, S.D.8
Lee, T.A.9
Weiss, K.B.10
Jensen, R.L.11
Marks, G.B.12
Gulsvik, A.13
Nizankowska-Mogilnicka, E.14
-
6
-
-
80053323633
-
-
National Centre for Health statistics, Hyattsville, MD, National Vital Statistics Reports. S010.
-
Minino AM, Xu J, Kochanek KD,. Deaths: Preliminary Data for 2008. National Centre for Health statistics, Hyattsville, MD, 2010; 59 (2). National Vital Statistics Reports. S010.
-
(2010)
Deaths: Preliminary Data for 2008
, vol.59
, Issue.2
-
-
Minino, A.M.1
Xu, J.2
Kochanek, K.D.3
-
8
-
-
67649777117
-
The natural history of chronic airflow obstruction revisited: An analysis of the Framingham Offspring Cohort
-
Kohansal R, Martinez-Camblor P, Agusti A, et al,. The natural history of chronic airflow obstruction revisited: an analysis of the Framingham Offspring Cohort. Am. J. Respir. Crit. Care Med. 2009; 180: 3-10.
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.180
, pp. 3-10
-
-
Kohansal, R.1
Martinez-Camblor, P.2
Agusti, A.3
-
9
-
-
33751236493
-
Developing COPD: A 25 year follow up study of the general population
-
DOI 10.1136/thx.2006.062802
-
Løkke A, Lange P, Scharling H, et al,. Developing COPD: a 25 year follow up study of the general population. Thorax 2006; 61: 935-9. (Pubitemid 44787161)
-
(2006)
Thorax
, vol.61
, Issue.11
, pp. 935-939
-
-
Lokke, A.1
Lange, P.2
Scharling, H.3
Fabricius, P.4
Vestbo, J.5
-
10
-
-
0034644185
-
Environmental and heritable factors in the causation of cancer: Analyses of cohorts of twins from Sweden, Denmark, and Finland
-
DOI 10.1056/NEJM200007133430201
-
Lichtenstein P, Holm NV, Verkasalo PK, et al,. Environmental and heritable factors in the causation of cancer: analyses of cohorts of twins from Sweden, Denmark and Finland. N. Eng. J. Med. 2000; 343: 78-85. (Pubitemid 30451850)
-
(2000)
New England Journal of Medicine
, vol.343
, Issue.2
, pp. 78-85
-
-
Lichtenstein, P.1
Holm, N.V.2
Verkasalo, P.K.3
Iliadou, A.4
Kaprio, J.5
Koskenvuo, M.6
Pukkala, E.7
Skytthe, A.8
Hemminki, K.9
-
11
-
-
0033190781
-
Genetic epidemiology of pulmonary function
-
Chen Y,. Genetic epidemiology of pulmonary function. Thorax 1999; 54: 818-24. (Pubitemid 29401545)
-
(1999)
Thorax
, vol.54
, Issue.9
, pp. 818-824
-
-
Chen, Y.1
-
12
-
-
0017362875
-
Quantitative relationships between cigarette smoking and ventilatory function
-
Burrows B, Knudson RJ, Cline MG, et al,. Qualitative relationships between cigarette smoking and ventilatory function. Am. Rev. Respir. Dis. 1977; 115: 195-205. (Pubitemid 8036155)
-
(1977)
American Review of Respiratory Disease
, vol.115
, Issue.2
, pp. 195-205
-
-
Burrows, B.1
Knudson, R.J.2
Cline, M.G.3
Lebowitz, M.D.4
-
13
-
-
0017715873
-
A common familial component in lung cancer and chronic obstructive pulmonary disease
-
Cohen BH, Diamond EL, Graves CVG, et al,. A common familial component in lung cancer and chronic obstructive pulmonary disease. Lancet 1977; September: 523-6. (Pubitemid 8186302)
-
(1977)
Lancet
, vol.2
, Issue.8037
, pp. 523-526
-
-
Cohen, B.H.1
Diamond, E.L.2
Graves, C.G.3
-
14
-
-
0023871240
-
Cumulative and reversible effects of lifetime smoking on simple tests of lung function in adults
-
Dockery DW, Speizer FE, Ferris BG, et al,. Cumulative and reversible effects of lifetime smoking on simple tests of lung function in adults. Am. Rev. Respir. Dis. 1988; 137: 286-92. (Pubitemid 18050173)
-
(1988)
American Review of Respiratory Disease
, vol.137
, Issue.2
, pp. 286-292
-
-
Dockery, D.W.1
Speizer, F.E.2
Ferris Jr., B.G.3
Ware, J.H.4
Louis, T.A.5
Spiro III, A.6
-
15
-
-
0023187149
-
Airways obstruction and the risk for lung cancer
-
Tockman MS, Anthonisen NR, Wright NC, et al,. Airways obstruction and the risk of lung cancer. Ann. Intern. Med. 1987; 106: 512-18. (Pubitemid 17095034)
-
(1987)
Annals of Internal Medicine
, vol.106
, Issue.4
, pp. 512-518
-
-
Tockman, M.S.1
Anthonisen, N.R.2
Wright, E.C.3
-
16
-
-
0038677958
-
Low lung function and incident lung cancer in the United States: Data from the First National Health and Nutrition Examination Survey follow-up
-
DOI 10.1001/archinte.163.12.1475
-
Mannino DM, Aguayo SM, Petty TL, et al,. Low lung function and incident lung cancer in the United States: data from the first NHANES follow-up. Arch. Intern. Med. 2003; 163: 1475-80. (Pubitemid 36758921)
-
(2003)
Archives of Internal Medicine
, vol.163
, Issue.12
, pp. 1475-1480
-
-
Mannino, D.M.1
Aguayo, S.M.2
Petty, T.L.3
Redd, S.C.4
-
17
-
-
69249086981
-
COPD prevalence is increased in lung cancer independence of age, gender and smoking history
-
Young RP, Hopkins RJ, Christmas T, et al,. COPD prevalence is increased in lung cancer independence of age, gender and smoking history. Eur. Respir. J. 2009; 34: 380-6.
-
(2009)
Eur. Respir. J.
, vol.34
, pp. 380-386
-
-
Young, R.P.1
Hopkins, R.J.2
Christmas, T.3
-
18
-
-
37449001170
-
Forced expiratory volume in one second: Not just a lung function test but a marker of premature death from all causes
-
DOI 10.1183/09031936.00021707
-
Young RP, Hopkins R, Eaton TE,. FEV1: not just a lung function test but a marker of premature death from all causes. Eur. Respir. J. 2007; 30: 616-22. (Pubitemid 351194819)
-
(2007)
European Respiratory Journal
, vol.30
, Issue.4
, pp. 616-622
-
-
Young, R.P.1
Hopkins, R.2
Eaton, T.E.3
-
19
-
-
41649103052
-
A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
-
DOI 10.1038/nature06846, PII NATURE06846
-
Thorgeirsson TE, Geller F, Sulem P, et al,. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature 2008; 452: 638-42. (Pubitemid 351483366)
-
(2008)
Nature
, vol.452
, Issue.7187
, pp. 638-642
-
-
Thorgeirsson, T.E.1
Geller, F.2
Sulem, P.3
Rafnar, T.4
Wiste, A.5
Magnusson, K.P.6
Manolescu, A.7
Thorleifsson, G.8
Stefansson, H.9
Ingason, A.10
Stacey, S.N.11
Bergthorsson, J.T.12
Thorlacius, S.13
Gudmundsson, J.14
Jonsson, T.15
Jakobsdottir, M.16
Saemundsdottir, J.17
Olafsdottir, O.18
Gudmundsson, L.J.19
Bjornsdottir, G.20
Kristjansson, K.21
Skuladottir, H.22
Isaksson, H.J.23
Gudbjartsson, T.24
Jones, G.T.25
Mueller, T.26
Gottsater, A.27
Flex, A.28
Aben, K.K.H.29
De Vegt, F.30
Mulders, P.F.A.31
Isla, D.32
Vidal, M.J.33
Asin, L.34
Saez, B.35
Murillo, L.36
Blondal, T.37
Kolbeinsson, H.38
Stefansson, J.G.39
Hansdottir, I.40
Runarsdottir, V.41
Pola, R.42
Lindblad, B.43
Van Rij, A.M.44
Dieplinger, B.45
Haltmayer, M.46
Mayordomo, J.I.47
Kiemeney, L.A.48
Matthiasson, S.E.49
Oskarsson, H.50
Tyrfingsson, T.51
Gudbjartsson, D.F.52
Gulcher, J.R.53
Jonsson, S.54
Thorsteinsdottir, U.55
Kong, A.56
Stefansson, K.57
more..
-
20
-
-
41649103682
-
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
-
DOI 10.1038/nature06885, PII NATURE06885
-
Hung RJ, McKay JD, Gaborieau V, et al,. A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature 2008; 452: 633-7. (Pubitemid 351483367)
-
(2008)
Nature
, vol.452
, Issue.7187
, pp. 633-637
-
-
Hung, R.J.1
McKay, J.D.2
Gaborieau, V.3
Boffetta, P.4
Hashibe, M.5
Zaridze, D.6
Mukeria, A.7
Szeszenia-Dabrowska, N.8
Lissowska, J.9
Rudnai, P.10
Fabianova, E.11
Mates, D.12
Bencko, V.13
Foretova, L.14
Janout, V.15
Chen, C.16
Goodman, G.17
Field, J.K.18
Liloglou, T.19
Xinarianos, G.20
Cassidy, A.21
McLaughlin, J.22
Liu, G.23
Narod, S.24
Krokan, H.E.25
Skorpen, F.26
Elvestad, M.B.27
Hveem, K.28
Vatten, L.29
Linseisen, J.30
Clavel-Chapelon, F.31
Vineis, P.32
Bueno-De-Mesquita, H.B.33
Lund, E.34
Martinez, C.35
Bingham, S.36
Rasmuson, T.37
Hainaut, P.38
Riboli, E.39
Ahrens, W.40
Benhamou, S.41
Lagiou, P.42
Trichopoulos, D.43
Holcatova, I.44
Merletti, F.45
Kjaerheim, K.46
Agudo, A.47
MacFarlane, G.48
Talamini, R.49
Simonato, L.50
Lowry, R.51
Conway, D.I.52
Znaor, A.53
Healy, C.54
Zelenika, D.55
Boland, A.56
Delepine, M.57
Foglio, M.58
Lechner, D.59
Matsuda, F.60
Blanche, H.61
Gut, I.62
Heath, S.63
Lathrop, M.64
Brennan, P.65
more..
-
21
-
-
42649091460
-
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
-
DOI 10.1038/ng.109, PII NG109
-
Amos CI, Wu X, Broderick P, et al,. Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat. Genet. 2008; 40: 616-22. (Pubitemid 351601203)
-
(2008)
Nature Genetics
, vol.40
, Issue.5
, pp. 616-622
-
-
Amos, C.I.1
Wu, X.2
Broderick, P.3
Gorlov, I.P.4
Gu, J.5
Eisen, T.6
Dong, Q.7
Zhang, Q.8
Gu, X.9
Vijayakrishnan, J.10
Sullivan, K.11
Matakidou, A.12
Wang, Y.13
Mills, G.14
Doheny, K.15
Tsai, Y.-Y.16
Chen, W.V.17
Shete, S.18
Spitz, M.R.19
Houlston, R.S.20
more..
-
22
-
-
33646591271
-
Functional variants of antioxidant genes in smokers with COPD and in those with normal lung function
-
DOI 10.1136/thx.2005.048512
-
Young RP, Hopkins R, Black PN, et al,. Functional variants of anti-oxidant genes in smokers with COPD and in those with normal lung function. Thorax 2006; 30: 394-9. (Pubitemid 43723321)
-
(2006)
Thorax
, vol.61
, Issue.5
, pp. 394-399
-
-
Young, R.P.1
Hopkins, R.2
Black, P.N.3
Eddy, C.4
Wu, L.5
Gamble, G.D.6
Mills, G.D.7
Garrett, J.E.8
Eaton, T.E.9
Rees, M.I.10
-
23
-
-
37549021114
-
Assessing the relationship between lung cancer risk and emphysema detected on low dose CT of the chest
-
de Torres J, Bastarrika G, Wisnivesky JP, et al,. Assessing the relationship between lung cancer risk and emphysema detected on low dose CT of the chest. Chest 2007; 132: 1932-8.
-
(2007)
Chest
, vol.132
, pp. 1932-1938
-
-
De Torres, J.1
Bastarrika, G.2
Wisnivesky, J.P.3
-
24
-
-
52749088978
-
Association of radiographic emphysema and airflow obstruction with lung cancer
-
Wilson DO, Weissfeld JL, Balkan A, et al,. Association of radiographic emphysema and airflow obstruction with lung cancer. Am. J. Respir. Crit. Care Med. 2008; 178: 738-44.
-
(2008)
Am. J. Respir. Crit. Care Med.
, vol.178
, pp. 738-744
-
-
Wilson, D.O.1
Weissfeld, J.L.2
Balkan, A.3
-
25
-
-
75149146123
-
Lung function predicts lung cancer risk in smokers: A tool for targeting screening programmes
-
Calabra E, Randi G, La Vecchia C, et al,. Lung function predicts lung cancer risk in smokers: a tool for targeting screening programmes. Eur. Respir. J. 2010; 35: 146-51.
-
(2010)
Eur. Respir. J.
, vol.35
, pp. 146-151
-
-
Calabra, E.1
Randi, G.2
La Vecchia, C.3
-
26
-
-
77953300661
-
Prevalence and under-diagnosis of chronic obstructive pulmonary disease among patients at risk in primary care
-
Hill K, Goldstein RS, Guyatt GH, et al,. Prevalence and under-diagnosis of chronic obstructive pulmonary disease among patients at risk in primary care. CMAJ 2010; 182: 673-8.
-
(2010)
CMAJ
, vol.182
, pp. 673-678
-
-
Hill, K.1
Goldstein, R.S.2
Guyatt, G.H.3
-
27
-
-
34548032087
-
Genome-wide association studies provide new insights into type 2 diabetes aetiology
-
DOI 10.1038/nrg2178, PII NRG2178
-
Frayling TM,. Genome-wide association studies provide new insights into type 2 diabetes aetiology. Nat. Rev. Genet. 2007; 8: 657-62. (Pubitemid 47281993)
-
(2007)
Nature Reviews Genetics
, vol.8
, Issue.9
, pp. 657-662
-
-
Frayling, T.M.1
-
28
-
-
27144456779
-
Are COPD and lung cancer two manifestations of the same disease?
-
DOI 10.1378/chest.128.4.1895
-
Petty TL,. Are COPD and lung cancer two manifestations of the same disease? Chest 2005; 128: 1895-7. (Pubitemid 41507515)
-
(2005)
Chest
, vol.128
, Issue.4
, pp. 1895-1897
-
-
Petty, T.L.1
-
29
-
-
64749083599
-
Lung cancer and chronic obstructive pulmonary disease: Needs and opportunities for integrated research
-
Punturieri A, Szabo E, Croxton TL, et al,. Lung cancer and chronic obstructive pulmonary disease: needs and opportunities for integrated research. JNCI 2009; 101: 554-9.
-
(2009)
JNCI
, vol.101
, pp. 554-559
-
-
Punturieri, A.1
Szabo, E.2
Croxton, T.L.3
-
30
-
-
58849140039
-
Lung cancer gene associated with COPD: Triple whammy or possible confounding effect?
-
Young RP, Hopkins RJ, Hay BA, et al,. Lung cancer gene associated with COPD: triple whammy or possible confounding effect? Eur. Respir. J. 2008; 32: 1158-64.
-
(2008)
Eur. Respir. J.
, vol.32
, pp. 1158-1164
-
-
Young, R.P.1
Hopkins, R.J.2
Hay, B.A.3
-
31
-
-
78649740699
-
Chromosome 4q31 locus in COPD also associated with lung cancer
-
Young RP, Whittington CF, Hopkins RJ, et al,. Chromosome 4q31 locus in COPD also associated with lung cancer. Eur. Respir. J. 2010; 36: 1375-82.
-
(2010)
Eur. Respir. J.
, vol.36
, pp. 1375-1382
-
-
Young, R.P.1
Whittington, C.F.2
Hopkins, R.J.3
-
32
-
-
79751516305
-
FAM13A locus in COPD independently associated with lung cancer-evidence of a molecular genetic link between COPD and lung cancer
-
Young RP, Hopkins RJ, Hay BA, et al,. FAM13A locus in COPD independently associated with lung cancer-evidence of a molecular genetic link between COPD and lung cancer. Appl. Clin. Genet. 2011; 4: 1-13.
-
(2011)
Appl. Clin. Genet.
, vol.4
, pp. 1-13
-
-
Young, R.P.1
Hopkins, R.J.2
Hay, B.A.3
-
33
-
-
77949911882
-
The COPD genetic association compendium: A comprehensive online data base of COPD genetic associations
-
Castaldi PJ, Cho MH, Cohn M, et al,. The COPD genetic association compendium: a comprehensive online data base of COPD genetic associations. Hum. Mol. Genet. 2009; 19: 526-34.
-
(2009)
Hum. Mol. Genet.
, vol.19
, pp. 526-534
-
-
Castaldi, P.J.1
Cho, M.H.2
Cohn, M.3
-
34
-
-
70349449892
-
Meta-analyses on suspected chronic obstructive pulmonary disease genes-a summary of 20 years research
-
Smolonska J, Wijmenga C, Postma DS, et al,. Meta-analyses on suspected chronic obstructive pulmonary disease genes-a summary of 20 years research. Am. J. Respir. Crit. Care Med. 2009; 180: 618-31.
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.180
, pp. 618-631
-
-
Smolonska, J.1
Wijmenga, C.2
Postma, D.S.3
-
35
-
-
41349107780
-
Glutathione S-transferase M1 (GSTM1) polymorphisms and lung cancer: A literature-based systematic HuGE review and meta-analysis
-
DOI 10.1093/aje/kwm383
-
Carlsten C, Sagoo GS, Frodsham AJ, et al,. Glutathione S-transferase M1 (GSTM1) polymorphisms and lung cancer: a literature based systematic HuGE review and meta-analysis. Am. J. Epidemiol. 2008; 167: 759-74. (Pubitemid 351451750)
-
(2008)
American Journal of Epidemiology
, vol.167
, Issue.7
, pp. 759-774
-
-
Carlsten, C.1
Sagoo, G.S.2
Frodsham, A.J.3
Burke, W.4
Higgins, J.P.T.5
-
36
-
-
55849112266
-
International lung cancer consortium: Pooled analysis of sequence variants in DNA repair and cell cycle pathways
-
Hung RJ, Christiani DC, Risch A, et al,. International lung cancer consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways. Cancer Epidemiol. Biomarkers Prev. 2008; 17: 3081-9.
-
(2008)
Cancer Epidemiol. Biomarkers Prev.
, vol.17
, pp. 3081-3089
-
-
Hung, R.J.1
Christiani, D.C.2
Risch, A.3
-
37
-
-
35748983541
-
Framingham heart study genome-wide association: Results for pulmonary function measures
-
Wilk J, Walter R, Laramie J, et al,. Framingham heart study genome-wide association: results for pulmonary function measures. BMC Med. Genet. 2007; 8 (S1): S8.
-
(2007)
BMC Med. Genet.
, vol.8
, Issue.S1
-
-
Wilk, J.1
Walter, R.2
Laramie, J.3
-
38
-
-
63449099623
-
A genome-wide association study of pulmonary function measures in the Framingham Heart Study
-
Wilk JB, Chen T, Gottlieb DJ, et al,. A genome-wide association study of pulmonary function measures in the Framingham Heart Study. PLoS Genet. 2009; 5: e1000429.
-
(2009)
PLoS Genet.
, vol.5
-
-
Wilk, J.B.1
Chen, T.2
Gottlieb, D.J.3
-
39
-
-
73349143302
-
Genome-wide association study identifies five loci associated with lung function
-
Repapi E, Sayers I, Wain LV, et al,. Genome-wide association study identifies five loci associated with lung function. Nat. Genet. 2009; 42: 36-44.
-
(2009)
Nat. Genet.
, vol.42
, pp. 36-44
-
-
Repapi, E.1
Sayers, I.2
Wain, L.V.3
-
40
-
-
73349111257
-
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function
-
Hancock DB, Eijgelsheim M, Wilk JB, et al,. Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat. Genet. 2009; 42: 45-52.
-
(2009)
Nat. Genet.
, vol.42
, pp. 45-52
-
-
Hancock, D.B.1
Eijgelsheim, M.2
Wilk, J.B.3
-
41
-
-
63449101907
-
A genome-wide association study in chronic obstructive pulmonary disease (COPD): Identification of two major susceptibility loci
-
Pillai SG, Ge D, Zhu G, et al,. A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci. PLoS Genet. 2009; 5: e1000421.
-
(2009)
PLoS Genet.
, vol.5
-
-
Pillai, S.G.1
Ge, D.2
Zhu, G.3
-
42
-
-
77649189442
-
Variants in FAM13A are associated with chronic obstructive pulmonary disease
-
Cho MH, Boutaoui N, Klanderman BJ, et al,. Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat. Genet. 2010; 42: 200-2.
-
(2010)
Nat. Genet.
, vol.42
, pp. 200-202
-
-
Cho, M.H.1
Boutaoui, N.2
Klanderman, B.J.3
-
43
-
-
79751471246
-
Individual and cumulative effects of GWAS susceptibility loci in lung cancer: Associations after genotyping for COPD
-
Young RP, Hopkins RJ, Whittington CF, et al,. Individual and cumulative effects of GWAS susceptibility loci in lung cancer: associations after genotyping for COPD. PLoS ONE. 2011; 6: e16476.
-
(2011)
PLoS ONE.
, vol.6
-
-
Young, R.P.1
Hopkins, R.J.2
Whittington, C.F.3
-
44
-
-
34447289205
-
The non-neuronal cholinergic system in the airways: An unappreciated regulatory role in pulmonary inflammation?
-
DOI 10.1016/j.pharmthera.2007.05.007, PII S0163725807000927
-
Gwilt CR, Donnelly LE, Rogers DF,. The non-neuronal cholinergic system in the airways: an unappreciated regulatory role in pulmonary inflammation? Pharmacol. Ther. 2007; 115: 208-22. (Pubitemid 47042914)
-
(2007)
Pharmacology and Therapeutics
, vol.115
, Issue.2
, pp. 208-222
-
-
Gwilt, C.R.1
Donnelly, L.E.2
Rogers, D.F.3
-
45
-
-
0242669237
-
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
-
DOI 10.1038/nature01493
-
Watkins DN, Berman DM, Burkholder SG, et al,. Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer. Nature 2003; 422: 313-17. (Pubitemid 36378358)
-
(2003)
Nature
, vol.422
, Issue.6929
, pp. 313-317
-
-
Watkins, D.N.1
Berman, D.M.2
Burkholder, S.G.3
Wang, B.4
Beachy, P.A.5
Baylin, S.B.6
-
46
-
-
33747293858
-
Rho GTPase Activating Proteins in Cancer Phenotypes
-
Kandpal RP,. Rho GTPase Activating Proteins in Cancer Phenotypes. Curr. Protein Pept. Sci. 2006; 7: 355-65.
-
(2006)
Curr. Protein Pept. Sci.
, vol.7
, pp. 355-365
-
-
Kandpal, R.P.1
-
47
-
-
66249127897
-
Cigarette smoke impairs clearance of apoptotic cells through oxidant-dependent activation of Rho A
-
Richens TR, Linderman DJ, Horstmann SA, et al,. Cigarette smoke impairs clearance of apoptotic cells through oxidant-dependent activation of Rho A. Am. J. Respir. Crit. Care Med. 2009; 179: 1011-21.
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.179
, pp. 1011-1021
-
-
Richens, T.R.1
Linderman, D.J.2
Horstmann, S.A.3
-
48
-
-
77952420518
-
E-Cadherin negatively regulates neoplastic growth in non-small cell lung cancer: Role of GTPases
-
Asnaghi L, Vass WC, Quadri R, et al,. E-Cadherin negatively regulates neoplastic growth in non-small cell lung cancer: role of GTPases. Oncogene 2010; 29: 2760-71.
-
(2010)
Oncogene
, vol.29
, pp. 2760-2771
-
-
Asnaghi, L.1
Vass, W.C.2
Quadri, R.3
-
49
-
-
73449091199
-
Pharmacological actions of statins: Potential utility in COPD
-
Young RP, Hopkins R, Eaton TE,. Pharmacological actions of statins: potential utility in COPD. Eur. Respir. Rev. 2009; 18: 222-32.
-
(2009)
Eur. Respir. Rev.
, vol.18
, pp. 222-232
-
-
Young, R.P.1
Hopkins, R.2
Eaton, T.E.3
-
50
-
-
80053334582
-
COPD and lung cancer: Are they both airways diseases?
-
(in press).
-
Young RP, Hopkins RJ,. COPD and lung cancer: are they both airways diseases? Chest 2011 (in press).
-
(2011)
Chest
-
-
Young, R.P.1
Hopkins, R.J.2
-
51
-
-
79952673351
-
Common pathogenic mechanisms and pathways in the development of COPD and lung cancer
-
Yang IA, Relan V, Wright CM, et al,. Common pathogenic mechanisms and pathways in the development of COPD and lung cancer. Expert Opin. Ther. Targets 2011; 15: 439-56.
-
(2011)
Expert Opin. Ther. Targets
, vol.15
, pp. 439-456
-
-
Yang, I.A.1
Relan, V.2
Wright, C.M.3
-
52
-
-
30344458199
-
Familial lung cancer: Genetic susceptibility and relationship to chronic obstructive pulmonary disease
-
DOI 10.1164/rccm.200502-235PP
-
Schwartz AG, Ruckdeschel JC,. Familial lung cancer: genetic susceptibility and relationship to chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 2006; 173: 16-22. (Pubitemid 43069784)
-
(2006)
American Journal of Respiratory and Critical Care Medicine
, vol.173
, Issue.1
, pp. 16-22
-
-
Schwartz, A.G.1
Ruckdeschel, J.C.2
-
53
-
-
66749141807
-
Systemic manifestations and co-morbidities of COPD
-
Barnes PJ, Celli BR,. Systemic manifestations and co-morbidities of COPD. Eur. Respir. J. 2009; 33: 1165-85.
-
(2009)
Eur. Respir. J.
, vol.33
, pp. 1165-1185
-
-
Barnes, P.J.1
Celli, B.R.2
-
54
-
-
70349682910
-
A gene based risk score for lung cancer susceptibility in smokers and ex-smokers
-
Young RP, Hopkins RJ, Hay BA, et al,. A gene based risk score for lung cancer susceptibility in smokers and ex-smokers. Postgrad. Med. J. 2009; 85: 515-24.
-
(2009)
Postgrad. Med. J.
, vol.85
, pp. 515-524
-
-
Young, R.P.1
Hopkins, R.J.2
Hay, B.A.3
-
55
-
-
65349122439
-
Lung cancer susceptibility model based on age, family history and genetic variants
-
Young RP, Hopkins RJ, Hay BA, et al,. Lung cancer susceptibility model based on age, family history and genetic variants. PLoS ONE 2009; 4: e5302.
-
(2009)
PLoS ONE
, vol.4
-
-
Young, R.P.1
Hopkins, R.J.2
Hay, B.A.3
-
56
-
-
77951622978
-
Link between COPD and lung cancer
-
Young RP, Hopkins RJ,. Link between COPD and lung cancer. Respir. Med. 2010; 104: 758-9.
-
(2010)
Respir. Med.
, vol.104
, pp. 758-759
-
-
Young, R.P.1
Hopkins, R.J.2
-
57
-
-
78649871572
-
COPD and lung cancer: Are they both airways diseases?
-
Strange C,. COPD and lung cancer: are they both airways diseases? Chest 2010; 138: 1289-90.
-
(2010)
Chest
, vol.138
, pp. 1289-1290
-
-
Strange, C.1
-
58
-
-
69349085538
-
Chronic obstructive pulmonary disease and lung cancer
-
COPD Update.
-
Potton E, McCaughan F, Janes S,. Chronic obstructive pulmonary disease and lung cancer. Respir Med. 2009; 5: 34-7. COPD Update.
-
(2009)
Respir Med.
, vol.5
, pp. 34-37
-
-
Potton, E.1
McCaughan, F.2
Janes, S.3
-
59
-
-
67449098637
-
Chronic inflammation, chronic obstructive pulmonary disease, and lung cancer
-
Lee G, Walser TC, Dubinett SM,. Chronic inflammation, chronic obstructive pulmonary disease, and lung cancer. Curr. Opin. Pulm. Med. 2009; 15: 303-7.
-
(2009)
Curr. Opin. Pulm. Med.
, vol.15
, pp. 303-307
-
-
Lee, G.1
Walser, T.C.2
Dubinett, S.M.3
-
60
-
-
33747838497
-
Chronic obstructive pulmonary disease, inflammation and lung cancer
-
Brody JS, Spira A,. Chronic obstructive pulmonary disease, inflammation and lung cancer. Proc. Am. Thorac. Soc. 2006; 3: 535-8.
-
(2006)
Proc. Am. Thorac. Soc.
, vol.3
, pp. 535-538
-
-
Brody, J.S.1
Spira, A.2
-
61
-
-
68849111316
-
Current concepts on the role of inflammation in COPD and lung cancer
-
Yao HW, Rahman I,. Current concepts on the role of inflammation in COPD and lung cancer. Curr. Opin. Pharmacol. 2009; 9: 375-83.
-
(2009)
Curr. Opin. Pharmacol.
, vol.9
, pp. 375-383
-
-
Yao, H.W.1
Rahman, I.2
-
63
-
-
39849096188
-
Gene expression profiling in patients with chronic obstructive pulmonary disease and lung cancer
-
DOI 10.1164/rccm.200703-390OC
-
Wang IM, Stepaniants S, Boie Y, et al,. Gene expression profiling in patients with chronic obstructive pulmonary disease and lung cancer. Am. J. Respir. Crit. Care Med. 2008; 177: 402-11. (Pubitemid 351317583)
-
(2008)
American Journal of Respiratory and Critical Care Medicine
, vol.177
, Issue.4
, pp. 402-411
-
-
Wang, I.-M.1
Stepaniants, S.2
Boie, Y.3
Mortimer, J.R.4
Kennedy, B.5
Elliott, M.6
Hayashi, S.7
Loy, L.8
Coulter, S.9
Cervino, S.10
Harris, J.11
Thornton, M.12
Raubertas, R.13
Roberts, C.14
Hogg, J.C.15
Crackower, M.16
O'Neill, G.17
Pare, P.D.18
-
64
-
-
59249107914
-
Stat3 downstream genes serve as biomarkers in human lung carcinomas and chronic obstructive pulmonary disease
-
Qu P, Roberts J, Li Y, et al,. Stat3 downstream genes serve as biomarkers in human lung carcinomas and chronic obstructive pulmonary disease. Lung Cancer 2009; 63: 341-7.
-
(2009)
Lung Cancer
, vol.63
, pp. 341-347
-
-
Qu, P.1
Roberts, J.2
Li, Y.3
-
66
-
-
79956366064
-
Unbalanced oxidant-induced DNA damage and repair in COPD; A link towards lung cancer
-
Caramori G, Adcock IM, Casolari P, et al,. Unbalanced oxidant-induced DNA damage and repair in COPD; a link towards lung cancer. Thorax 2011; 66: 521-7.
-
(2011)
Thorax
, vol.66
, pp. 521-527
-
-
Caramori, G.1
Adcock, I.M.2
Casolari, P.3
-
67
-
-
49649127169
-
Multifaceted mechanisms in COPD: Inflammation, immunity and tissue repair and destruction
-
Chung KF, Adcock IM,. Multifaceted mechanisms in COPD: inflammation, immunity and tissue repair and destruction. Eur. Respir. J. 2008; 31: 1334-55.
-
(2008)
Eur. Respir. J.
, vol.31
, pp. 1334-1355
-
-
Chung, K.F.1
Adcock, I.M.2
-
68
-
-
66649127821
-
Immunologic Aspects of Chronic Obstructive Pulmonary Disease
-
Cosio MG, Saetta M, Agusti A,. Immunologic Aspects of Chronic Obstructive Pulmonary Disease. N. Engl. J. Med. 2009; 360: 2445-54.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 2445-2454
-
-
Cosio, M.G.1
Saetta, M.2
Agusti, A.3
-
69
-
-
65649102628
-
Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease
-
Borchers MT, Wesselkamper SC, Curull V, et al,. Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease. J. Clin. Invest. 2009; 119: 636-49.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 636-649
-
-
Borchers, M.T.1
Wesselkamper, S.C.2
Curull, V.3
-
70
-
-
77951919227
-
Inducible Innate Resistance of Lung Epithelium to Infection
-
Evans SE, Xu Y, Tuvim MJ, et al,. Inducible Innate Resistance of Lung Epithelium to Infection. Annu. Rev. Physiol. 2010; 72: 413-35.
-
(2010)
Annu. Rev. Physiol.
, vol.72
, pp. 413-435
-
-
Evans, S.E.1
Xu, Y.2
Tuvim, M.J.3
-
71
-
-
77954919917
-
Reticular basement membrane fragmentation and potential mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease
-
Sohal SS, Reid D, Soltani A, et al,. Reticular basement membrane fragmentation and potential mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease. Respirology 2010; 15: 930-8.
-
(2010)
Respirology
, vol.15
, pp. 930-938
-
-
Sohal, S.S.1
Reid, D.2
Soltani, A.3
-
72
-
-
33745600428
-
Epithelial-mesenchymal transition in lung cancer: Is tobacco the "smoking gun"?
-
DOI 10.1165/rcmb.2006-0051SF
-
Dasari V, Gallup M, Lemjabbar H, et al,. Epithelial-mesenchymal transition in lung cancer: is tobacco the 'smoking gun'? Am. J. Respir. Cell Mol. Biol. 2006; 35: 3-9. (Pubitemid 43993148)
-
(2006)
American Journal of Respiratory Cell and Molecular Biology
, vol.35
, Issue.1
, pp. 3-9
-
-
Dasari, V.1
Gallup, M.2
Lemjabbar, H.3
Maltseva, I.4
McNamara, N.5
-
73
-
-
37549053307
-
Collagen 1 promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-β signalling
-
Shintani Y, Maeda M, Chaika N, et al,. Collagen 1 promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-β signalling. Am. J. Respir. Cell Mol. Biol. 2008; 38: 95-104.
-
(2008)
Am. J. Respir. Cell Mol. Biol.
, vol.38
, pp. 95-104
-
-
Shintani, Y.1
Maeda, M.2
Chaika, N.3
-
74
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
Kalluri R, Weinberg RA,. The basics of epithelial-mesenchymal transition. J. Clin. Invest. 2009; 119: 1420-8.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
75
-
-
34548583283
-
Requirement for Rac1 in a K-ras-induced lung cancer in the mouse
-
DOI 10.1158/0008-5472.CAN-07-2300
-
Kissil JL, Walmsley MJ, Hanlon L, et al,. Requirement for Rac1 in a K-ras-induced lung cancer in the Mouse. Cancer Res. 2007; 67: 8089-94. (Pubitemid 47395143)
-
(2007)
Cancer Research
, vol.67
, Issue.17
, pp. 8089-8094
-
-
Kissil, J.L.1
Walmsley, M.J.2
Hanlon, L.3
Haigis, K.M.4
Kim, C.F.B.5
Sweet-Cordero, A.6
Eckman, M.S.7
Tuveson, D.A.8
Capobianco, A.J.9
Tybulewicz, V.L.J.10
Jacks, T.11
-
76
-
-
0034658674
-
Oncogenic Ras down regulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition
-
Zondag GCM, Evers EE, ten Klooster JP, et al,. Oncogenic Ras down regulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition. J. Cell Biol. 2000; 149: 775-82.
-
(2000)
J. Cell Biol.
, vol.149
, pp. 775-782
-
-
Zondag, G.C.M.1
Evers, E.E.2
Ten Klooster, J.P.3
-
77
-
-
69249242839
-
Chronic airflow obstruction and markers of systemic inflammation: Results from the BOLD study in Iceland
-
Thorleifsson SJ, Margretardottir OB, Gudmundsson G, et al,. Chronic airflow obstruction and markers of systemic inflammation: results from the BOLD study in Iceland. Respir. Med. 2009; 103: 1548-53.
-
(2009)
Respir. Med.
, vol.103
, pp. 1548-1553
-
-
Thorleifsson, S.J.1
Margretardottir, O.B.2
Gudmundsson, G.3
-
78
-
-
0033214242
-
Evaluation of interleukin-6 in bronchoalveolar lavage fluid and serum of patients with lung cancer
-
DOI 10.1016/S0022-2143(99)90156-7
-
Dowlati A, Levitan N, Remick SC,. Evaluation of interleukin-6 in bronchoalveolar lavage fluid and serum of patients with lung cancer. J. Lab. Clin. Med. 1999; 134: 405-9. (Pubitemid 29490161)
-
(1999)
Journal of Laboratory and Clinical Medicine
, vol.134
, Issue.4
, pp. 405-409
-
-
Dowlati, A.1
Levitan, N.2
Remick, S.C.3
-
79
-
-
84892907273
-
Mounting evidence that IL-6 contributes to lung cancer
-
November: 17.
-
Begany T,. Mounting evidence that IL-6 contributes to lung cancer. Pulm. Rev. 2005; November: 17.
-
(2005)
Pulm. Rev.
-
-
Begany, T.1
-
80
-
-
40849114627
-
Oncogenic Ras-induced secretion of IL-6 is required for tumorigenesis
-
Ancrile B, Lim K-H, Counter CM,. Oncogenic Ras-induced secretion of IL-6 is required for tumorigenesis. Mol. Interv. 2008; 8: 22-7.
-
(2008)
Mol. Interv.
, vol.8
, pp. 22-27
-
-
Ancrile, B.1
Lim, K.-H.2
Counter, C.M.3
-
81
-
-
73149099640
-
Mechanisms of lung development-contribution to adult lung disease and relevance to chronic obstructive pulmonary disease
-
Shi W, Chen F, Cardoso WV,. Mechanisms of lung development-contribution to adult lung disease and relevance to chronic obstructive pulmonary disease. Proc. Am. Thorac. Soc. 2009; 6: 558-63.
-
(2009)
Proc. Am. Thorac. Soc.
, vol.6
, pp. 558-563
-
-
Shi, W.1
Chen, F.2
Cardoso, W.V.3
-
82
-
-
20144379879
-
Statins reduce interleukin-6-induced C-reactive protein in human hepatocytes: New evidence for direct antiinflammatory effects of statins
-
DOI 10.1161/01.ATV.0000163840.63685.0c
-
Arnaud C, Burger F, Steffens S, et al,. Statins reduce interleukin-6 induced C-reactive protein in human hepatocytes: new evidence for direct anti-inflammatory effects of statins. Arterioscler. Thromb. Vasc. Biol. 2005; 25: 1231-6. (Pubitemid 40776614)
-
(2005)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.25
, Issue.6
, pp. 1231-1236
-
-
Arnaud, C.1
Burger, F.2
Steffens, S.3
Veillard, N.R.4
Nguyen, T.H.5
Trono, D.6
Mach, F.7
-
83
-
-
57349193494
-
Smoking and lung cancer-the role of inflammation
-
Walser T, Cui X, Yanagawa J, et al,. Smoking and lung cancer-the role of inflammation. Proc. Am. Thorac. Soc. 2008; 5: 811-15.
-
(2008)
Proc. Am. Thorac. Soc.
, vol.5
, pp. 811-815
-
-
Walser, T.1
Cui, X.2
Yanagawa, J.3
-
84
-
-
33748676495
-
Inhibitory effect of statins on renal epithelial-to-mesenchymal transition
-
DOI 10.1159/000094780
-
Patel S, Mason RM, Suzuki J, et al,. Inhibitory effect of statins on renal Epithelial-to-Mesenchymal Transition. Am. J. Nephrol. 2006; 26: 381-7. (Pubitemid 44394157)
-
(2006)
American Journal of Nephrology
, vol.26
, Issue.4
, pp. 381-387
-
-
Patel, S.1
Mason, R.M.2
Suzuki, J.3
Imaizumi, A.4
Kamimura, T.5
Zhang, Z.6
-
85
-
-
68149180708
-
Potential benefits of statins on morbidity and mortality in COPD: A review of the evidence
-
Young RP, Hopkins RJ, Eaton TE,. Potential benefits of statins on morbidity and mortality in COPD: a review of the evidence. Postgrad. Med. J. 2009; 85: 414-21.
-
(2009)
Postgrad. Med. J.
, vol.85
, pp. 414-421
-
-
Young, R.P.1
Hopkins, R.J.2
Eaton, T.E.3
-
86
-
-
77953498263
-
Lung function predicts lung cancer
-
Young R, Hopkins R,. Lung function predicts lung cancer. Eur. Respir. J. 2010; 35: 1421-2.
-
(2010)
Eur. Respir. J.
, vol.35
, pp. 1421-1422
-
-
Young, R.1
Hopkins, R.2
-
87
-
-
0034609239
-
Smoking, smoking cessation, and lung cancer in the UK since 1950: Combination of national statistics with two case-control studies
-
Peto R, Darby S, Deo H, et al,. Smoking, smoking cessation, and lung cancer in the UK since 1950: combination of national statistics with two case-control studies. Br. Med. J. 2000; 321: 323-9. (Pubitemid 30496873)
-
(2000)
British Medical Journal
, vol.321
, Issue.7257
, pp. 323-329
-
-
Peto, R.1
Darby, S.2
Deo, H.3
Silcocks, P.4
Whitley, E.5
Doll, R.6
-
88
-
-
72649085927
-
Re: Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk
-
Spitz MR, Amos CI, D'Amellio A, et al,. Re: discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk. JNCI 2009; 24: 1731-2.
-
(2009)
JNCI
, vol.24
, pp. 1731-1732
-
-
Spitz, M.R.1
Amos, C.I.2
D'Amellio, A.3
-
89
-
-
74749100450
-
Smoking cessation: The potential role of risk assessment tools as motivational triggers
-
Young RP, Hopkins RJ, Smith M, et al,. Smoking cessation: the potential role of risk assessment tools as motivational triggers. Postgrad. Med. J. 2010; 86: 26-33.
-
(2010)
Postgrad. Med. J.
, vol.86
, pp. 26-33
-
-
Young, R.P.1
Hopkins, R.J.2
Smith, M.3
-
90
-
-
33847209577
-
Does genetic testing result in behavioral health change? Changes in smoking behavior following testing for alpha-1 antitrypsin deficiency
-
Carpenter MJ, Strange C, Jones Y, et al,. Does genetic testing result in behavioral health change? Changes in smoking behavior following testing for alpha-1 antitrypsin deficiency. Ann. Behav. Med. 2007; 33: 22-8.
-
(2007)
Ann. Behav. Med.
, vol.33
, pp. 22-28
-
-
Carpenter, M.J.1
Strange, C.2
Jones, Y.3
-
91
-
-
84856522976
-
TM) Motivates Smoking Cessation in Randomly Selected Smokers. Abstract #A65
-
TM) Motivates Smoking Cessation In Randomly Selected Smokers. Abstract #A65. AACR 2010; 3 (12 Suppl.): A65.
-
(2010)
AACR
, vol.3
, Issue.12 SUPPL.
-
-
Hopkins, R.J.1
Young, R.P.2
Hay, B.A.3
-
92
-
-
19044365314
-
Lung cancer detection in patients with airflow obstruction identified in a primary care outpatient practice
-
DOI 10.1378/chest.127.4.1140
-
Bechtel JJ, Kelley WA, Coons TA, et al,. Lung cancer detection in patients with airflow obstruction identified in a primary care outpatient practice. Chest 2005; 127: 1140-5. (Pubitemid 46224273)
-
(2005)
Chest
, vol.127
, Issue.4
, pp. 1140-1145
-
-
Bechtel, J.J.1
Kelley, W.A.2
Coons, T.A.3
Klein, M.G.4
Slagel, D.D.5
Petty, T.L.6
-
93
-
-
33750315764
-
Survival of patients with stage 1 lung cancer detected on CT screening
-
IELCAP Investigators.
-
IELCAP Investigators. Survival of patients with stage 1 lung cancer detected on CT screening. NEJM 2006; 355: 1763-71.
-
(2006)
NEJM
, vol.355
, pp. 1763-1771
-
-
|