Sepsis-Induced Thymic Atrophy Is Associated with Defects in Early Lymphopoiesis

Stem Cells

Volumn 34, Issue 12, 2016, Pages 2902-2915

  Kong, Yaxian ^a,b   Li, Yajie ^a,b   Zhang, Weimei ^a,b   Yuan, Shaoxin ^a,b   Winkler, René ^c   Kröhnert, Ulrike ^c   Han, Junyan ^a,b   Lin, Tao ^a,b   Zhou, Yu ^d   Miao, Peng ^e   Wang, Beibei ^a,b   Zhang, Jianping ^a,b   Yu, Zhengya ^e   Zhang, Yu ^d   Kosan, Christian ^c   Zeng, Hui ^a,b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b Beijing Key Laboratory of Emerging Infectious Diseases   (China)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^e CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Emergency hematopoiesis; Hematopoietic stem cells; Lineage commitment; Sepsis; T lymphopoiesis; Thymic atrophy

Indexed keywords

CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CCR9; LIPOPOLYSACCHARIDE; MESSENGER RNA; PADGEM PROTEIN; POLYINOSINIC POLYCYTIDYLIC ACID; CHEMOKINE RECEPTOR; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL LINEAGE; CELL PROLIFERATION; CONTROLLED STUDY; HEMATOPOIETIC STEM CELL; LYMPHOCYTE DEPLETION; LYMPHOCYTE MIGRATION; LYMPHOCYTOPENIA; LYMPHOPOIESIS; MOUSE; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; RNA SEQUENCE; SEPSIS; T LYMPHOCYTE; THYMUS ATROPHY; AGONISTS; ANIMAL; ATROPHY; BONE MARROW CELL; C57BL MOUSE; COMPLICATION; CYTOLOGY; DRUG EFFECTS; EXTRAMEDULLARY HEMATOPOIESIS; GENE EXPRESSION PROFILING; GENETICS; LYMPHOCYTE COUNT; MALE; METABOLISM; MYELOPOIESIS; PATHOLOGY; THYMUS;

ANIMALS; ATROPHY; BONE MARROW CELLS; CELL LINEAGE; CELL PROLIFERATION; GENE EXPRESSION PROFILING; HEMATOPOIESIS, EXTRAMEDULLARY; HEMATOPOIETIC STEM CELLS; LIPOPOLYSACCHARIDES; LYMPHOCYTE COUNT; LYMPHOPOIESIS; MALE; MICE, INBRED C57BL; MYELOPOIESIS; POLY I-C; RECEPTORS, CHEMOKINE; SEPSIS; T-LYMPHOCYTES; THYMUS GLAND; TOLL-LIKE RECEPTORS;

EID: 84980028611     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2464     Document Type: Article

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