Restriction by SAMHD1 Limits cGAS/STING-Dependent Innate and Adaptive Immune Responses to HIV-1

Cell Reports

Volumn 16, Issue 6, 2016, Pages 1492-1501

  Maelfait, Jonathan ^a   Bridgeman, Anne ^a   Benlahrech, Adel ^b   Cursi, Chiara ^a   Rehwinkel, Jan ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA; CGAS PROTEIN; HYDROLASE; INTERFERON; INTERFERON RECEPTOR; SAMHD1 PROTEIN; STING PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; BETA INTERFERON; DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1; MB21D1 PROTEIN, MOUSE; MEMBRANE PROTEIN; MPYS PROTEIN, MOUSE; NUCLEOTIDYLTRANSFERASE; SAMHD1 PROTEIN, MOUSE;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL ACTIVATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOSOL; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOREGULATION; INNATE IMMUNITY; INTERFERON PRODUCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN FUNCTION; REVERSE TRANSCRIPTION; SIGNAL TRANSDUCTION; VIRUS CELL INTERACTION; VIRUS IMMUNITY; ANIMAL; C57BL MOUSE; DEFICIENCY; DENDRITIC CELL; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; METABOLISM; VIRUS REPLICATION;

ADAPTIVE IMMUNITY; ANIMALS; DENDRITIC CELLS; HIV INFECTIONS; HIV-1; IMMUNITY, INNATE; INTERFERON-BETA; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NUCLEOTIDYLTRANSFERASES; SAM DOMAIN AND HD DOMAIN-CONTAINING PROTEIN 1; VIRUS REPLICATION;

EID: 84979740219     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.07.002     Document Type: Article

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