Endogenous TRIM5α Function Is Regulated by SUMOylation and Nuclear Sequestration for Efficient Innate Sensing in Dendritic Cells

Cell Reports

Volumn 14, Issue 2, 2016, Pages 355-369

  Portilho, Débora M ^a   Fernandez, Juliette ^a   Ringeard, Mathieu ^b   Machado, Anthony K ^a   Boulay, Aude ^a   Mayer, Martha ^c   Müller Trutwin, Michaela ^b   Beignon, Anne Sophie ^d   Kirchhoff, Frank ^c   Nisole, Sébastien ^e   Arhel, Nathalie J ^a  

^a INSERM   (France)

^b INSTITUT PASTEUR   (France)

^c UNIVERSITY HOSPITAL ULM   (Germany)

^d CEA   (France)

^e Centre Universitaire des Saints Pères   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GINKGOLIC ACID; INTERFERON; MESSENGER RNA; PROTEIN INHIBITOR; TRIPARTITE MOTIF PROTEIN 5; UNCLASSIFIED DRUG; PROTEIN; TRIM5(ALPHA) PROTEIN, RHESUS MONKEY;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL FUNCTION; CELL NUCLEUS INCLUSION BODY; CELLULAR DISTRIBUTION; COILED BODY; CONTROLLED STUDY; DENDRITIC CELL; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INNATE IMMUNITY; INTERFERON INDUCTION; MALE; NONHUMAN; NUCLEAR SEQUESTRATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RETROVIRIDAE; RETROVIRUS INFECTION; REVERSE TRANSCRIPTION; RHESUS MONKEY; SUMOYLATION; TRIMALPHA GENE; VIRUS INHIBITION; ANIMAL; GENETICS; METABOLISM;

ANIMALS; DENDRITIC CELLS; HUMANS; MACACA MULATTA; PROTEINS; SUMOYLATION;

EID: 84955401096     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.12.039     Document Type: Article

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