-
1
-
-
82855170846
-
Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction
-
Alers, S., Löffler, A.S., Paasch, F., Dieterle, A.M., Keppeler, H., Lauber, K., Campbell, D.G., Fehrenbacher, B., Schaller, M., Wesselborg, S., Stork, B., Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction. Autophagy 7 (2011), 1423–1433.
-
(2011)
Autophagy
, vol.7
, pp. 1423-1433
-
-
Alers, S.1
Löffler, A.S.2
Paasch, F.3
Dieterle, A.M.4
Keppeler, H.5
Lauber, K.6
Campbell, D.G.7
Fehrenbacher, B.8
Schaller, M.9
Wesselborg, S.10
Stork, B.11
-
2
-
-
65249155441
-
An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation
-
Chang, Y.Y., Neufeld, T.P., An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation. Mol. Biol. Cell 20 (2009), 2004–2014.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 2004-2014
-
-
Chang, Y.Y.1
Neufeld, T.P.2
-
3
-
-
84943777762
-
Molecular interactions of the Saccharomyces cerevisiae Atg1 complex provide insights into assembly and regulatory mechanisms
-
Chew, L.H., Lu, S., Liu, X., Li, F.K., Yu, A.Y., Klionsky, D.J., Dong, M.Q., Yip, C.K., Molecular interactions of the Saccharomyces cerevisiae Atg1 complex provide insights into assembly and regulatory mechanisms. Autophagy 11 (2015), 891–905.
-
(2015)
Autophagy
, vol.11
, pp. 891-905
-
-
Chew, L.H.1
Lu, S.2
Liu, X.3
Li, F.K.4
Yu, A.Y.5
Klionsky, D.J.6
Dong, M.Q.7
Yip, C.K.8
-
4
-
-
39449108917
-
The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae
-
Cheong, H., Nair, U., Geng, J., Klionsky, D.J., The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae. Mol. Biol. Cell 19 (2008), 668–681.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 668-681
-
-
Cheong, H.1
Nair, U.2
Geng, J.3
Klionsky, D.J.4
-
5
-
-
84877628647
-
Autophagy in human health and disease
-
Choi, A.M., Ryter, S.W., Levine, B., Autophagy in human health and disease. N. Engl. J. Med. 368 (2013), 651–662.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 651-662
-
-
Choi, A.M.1
Ryter, S.W.2
Levine, B.3
-
6
-
-
84891747382
-
The machinery of macroautophagy
-
Feng, Y., He, D., Yao, Z., Klionsky, D.J., The machinery of macroautophagy. Cell Res. 24 (2014), 24–41.
-
(2014)
Cell Res.
, vol.24
, pp. 24-41
-
-
Feng, Y.1
He, D.2
Yao, Z.3
Klionsky, D.J.4
-
7
-
-
84901986623
-
Structural basis of starvation-induced assembly of the autophagy initiation complex
-
Fujioka, Y., Suzuki, S.W., Yamamoto, H., Kondo-Kakuta, C., Kimura, Y., Hirano, H., Akada, R., Inagaki, F., Ohsumi, Y., Noda, N.N., Structural basis of starvation-induced assembly of the autophagy initiation complex. Nat. Struct. Mol. Biol. 21 (2014), 513–521.
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 513-521
-
-
Fujioka, Y.1
Suzuki, S.W.2
Yamamoto, H.3
Kondo-Kakuta, C.4
Kimura, Y.5
Hirano, H.6
Akada, R.7
Inagaki, F.8
Ohsumi, Y.9
Noda, N.N.10
-
8
-
-
66449083078
-
ULK1-ATG13-FIP200 complex mediates mTOR signaling and is essential for autophagy
-
Ganley, I.G., Lam, D.H., Wang, J., Ding, X., Chen, S., Jiang, X., ULK1-ATG13-FIP200 complex mediates mTOR signaling and is essential for autophagy. J. Biol. Chem. 284 (2009), 12297–12305.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 12297-12305
-
-
Ganley, I.G.1
Lam, D.H.2
Wang, J.3
Ding, X.4
Chen, S.5
Jiang, X.6
-
9
-
-
47549086520
-
Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopy
-
Geng, J., Baba, M., Nair, U., Klionsky, D.J., Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopy. J. Cell Biol. 182 (2008), 129–140.
-
(2008)
J. Cell Biol.
, vol.182
, pp. 129-140
-
-
Geng, J.1
Baba, M.2
Nair, U.3
Klionsky, D.J.4
-
10
-
-
84875365804
-
Autophagosomes form at ER-mitochondria contact sites
-
Hamasaki, M., Furuta, N., Matsuda, A., Nezu, A., Yamamoto, A., Fujita, N., Oomori, H., Noda, T., Haraguchi, T., Hiraoka, Y., et al. Autophagosomes form at ER-mitochondria contact sites. Nature 495 (2013), 389–393.
-
(2013)
Nature
, vol.495
, pp. 389-393
-
-
Hamasaki, M.1
Furuta, N.2
Matsuda, A.3
Nezu, A.4
Yamamoto, A.5
Fujita, N.6
Oomori, H.7
Noda, T.8
Haraguchi, T.9
Hiraoka, Y.10
-
11
-
-
65249119430
-
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy
-
Hosokawa, N., Hara, T., Kaizuka, T., Kishi, C., Takamura, A., Miura, Y., Iemura, S., Natsume, T., Takehana, K., Yamada, N., et al. Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. Mol. Biol. Cell 20 (2009), 1981–1991.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1981-1991
-
-
Hosokawa, N.1
Hara, T.2
Kaizuka, T.3
Kishi, C.4
Takamura, A.5
Miura, Y.6
Iemura, S.7
Natsume, T.8
Takehana, K.9
Yamada, N.10
-
12
-
-
84898639632
-
Atomistic autophagy: the structures of cellular self-digestion
-
Hurley, J.H., Schulman, B.A., Atomistic autophagy: the structures of cellular self-digestion. Cell 157 (2014), 300–311.
-
(2014)
Cell
, vol.157
, pp. 300-311
-
-
Hurley, J.H.1
Schulman, B.A.2
-
13
-
-
77955884684
-
Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins
-
Itakura, E., Mizushima, N., Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins. Autophagy 6 (2010), 764–776.
-
(2010)
Autophagy
, vol.6
, pp. 764-776
-
-
Itakura, E.1
Mizushima, N.2
-
14
-
-
84875834380
-
A HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagy
-
Jao, C.C., Ragusa, M.J., Stanley, R.E., Hurley, J.H., A HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagy. Proc. Natl. Acad. Sci. USA 110 (2013), 5486–5491.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 5486-5491
-
-
Jao, C.C.1
Ragusa, M.J.2
Stanley, R.E.3
Hurley, J.H.4
-
15
-
-
65249176304
-
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
-
Jung, C.H., Jun, C.B., Ro, S.H., Kim, Y.M., Otto, N.M., Cao, J., Kundu, M., Kim, D.H., ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol. Biol. Cell 20 (2009), 1992–2003.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1992-2003
-
-
Jung, C.H.1
Jun, C.B.2
Ro, S.H.3
Kim, Y.M.4
Otto, N.M.5
Cao, J.6
Kundu, M.7
Kim, D.H.8
-
16
-
-
18244394277
-
Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy
-
Kabeya, Y., Kamada, Y., Baba, M., Takikawa, H., Sasaki, M., Ohsumi, Y., Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy. Mol. Biol. Cell 16 (2005), 2544–2553.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 2544-2553
-
-
Kabeya, Y.1
Kamada, Y.2
Baba, M.3
Takikawa, H.4
Sasaki, M.5
Ohsumi, Y.6
-
17
-
-
0034683568
-
Tor-mediated induction of autophagy via an Apg1 protein kinase complex
-
Kamada, Y., Funakoshi, T., Shintani, T., Nagano, K., Ohsumi, M., Ohsumi, Y., Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J. Cell Biol. 150 (2000), 1507–1513.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1507-1513
-
-
Kamada, Y.1
Funakoshi, T.2
Shintani, T.3
Nagano, K.4
Ohsumi, M.5
Ohsumi, Y.6
-
18
-
-
84938744997
-
Receptor-bound targets of selective autophagy use a scaffold protein to activate the Atg1 kinase
-
Kamber, R.A., Shoemaker, C.J., Denic, V., Receptor-bound targets of selective autophagy use a scaffold protein to activate the Atg1 kinase. Mol. Cell 59 (2015), 372–381.
-
(2015)
Mol. Cell
, vol.59
, pp. 372-381
-
-
Kamber, R.A.1
Shoemaker, C.J.2
Denic, V.3
-
19
-
-
43149125546
-
Organization of the pre-autophagosomal structure responsible for autophagosome formation
-
Kawamata, T., Kamada, Y., Kabeya, Y., Sekito, T., Ohsumi, Y., Organization of the pre-autophagosomal structure responsible for autophagosome formation. Mol. Biol. Cell 19 (2008), 2039–2050.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 2039-2050
-
-
Kawamata, T.1
Kamada, Y.2
Kabeya, Y.3
Sekito, T.4
Ohsumi, Y.5
-
20
-
-
0026640551
-
Aminopeptidase I of Saccharomyces cerevisiae is localized to the vacuole independent of the secretory pathway
-
Klionsky, D.J., Cueva, R., Yaver, D.S., Aminopeptidase I of Saccharomyces cerevisiae is localized to the vacuole independent of the secretory pathway. J. Cell Biol. 119 (1992), 287–299.
-
(1992)
J. Cell Biol.
, vol.119
, pp. 287-299
-
-
Klionsky, D.J.1
Cueva, R.2
Yaver, D.S.3
-
21
-
-
84930188743
-
Solution structure of the Atg1 complex: implications for the architecture of the phagophore assembly site
-
Köfinger, J., Ragusa, M.J., Lee, I.H., Hummer, G., Hurley, J.H., Solution structure of the Atg1 complex: implications for the architecture of the phagophore assembly site. Structure 5 (2015), 809–818.
-
(2015)
Structure
, vol.5
, pp. 809-818
-
-
Köfinger, J.1
Ragusa, M.J.2
Lee, I.H.3
Hummer, G.4
Hurley, J.H.5
-
22
-
-
77953714711
-
Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling
-
Lin, S.C., Lo, Y.C., Wu, H., Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature 465 (2010), 885–890.
-
(2010)
Nature
, vol.465
, pp. 885-890
-
-
Lin, S.C.1
Lo, Y.C.2
Wu, H.3
-
23
-
-
0030983504
-
Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae
-
Matsuura, A., Tsukada, M., Wada, Y., Ohsumi, Y., Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae. Gene 19 (1997), 245–250.
-
(1997)
Gene
, vol.19
, pp. 245-250
-
-
Matsuura, A.1
Tsukada, M.2
Wada, Y.3
Ohsumi, Y.4
-
24
-
-
81055144784
-
Autophagy: renovation of cells and tissues
-
Mizushima, N., Komatsu, M., Autophagy: renovation of cells and tissues. Cell 147 (2011), 728–741.
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
25
-
-
80054025654
-
The role of Atg proteins in autophagosome formation
-
Mizushima, N., Yoshimori, T., Ohsumi, Y., The role of Atg proteins in autophagosome formation. Annu. Rev. Cell Dev. Biol. 27 (2011), 107–132.
-
(2011)
Annu. Rev. Cell Dev. Biol.
, vol.27
, pp. 107-132
-
-
Mizushima, N.1
Yoshimori, T.2
Ohsumi, Y.3
-
26
-
-
84892805825
-
Atg17/FIP200 localizes to perilysosomal Ref(2)P aggregates and promotes autophagy by activation of Atg1 in Drosophila
-
Nagy, P., Kárpáti, M., Varga, A., Pircs, K., Venkei, Z., Takáts, S., Varga, K., Erdi, B., Hegedűs, K., Juhász, G., Atg17/FIP200 localizes to perilysosomal Ref(2)P aggregates and promotes autophagy by activation of Atg1 in Drosophila. Autophagy 10 (2014), 453–467.
-
(2014)
Autophagy
, vol.10
, pp. 453-467
-
-
Nagy, P.1
Kárpáti, M.2
Varga, A.3
Pircs, K.4
Venkei, Z.5
Takáts, S.6
Varga, K.7
Erdi, B.8
Hegedűs, K.9
Juhász, G.10
-
27
-
-
67649467294
-
Dynamics and diversity in autophagy mechanisms: lessons from yeast
-
Nakatogawa, H., Suzuki, K., Kamada, Y., Ohsumi, Y., Dynamics and diversity in autophagy mechanisms: lessons from yeast. Nat. Rev. Mol. Cell Biol. 10 (2009), 458–467.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 458-467
-
-
Nakatogawa, H.1
Suzuki, K.2
Kamada, Y.3
Ohsumi, Y.4
-
28
-
-
0029036915
-
Novel system for monitoring autophagy in the yeast Saccharomyces cerevisiae
-
Noda, T., Matsuura, A., Wada, Y., Ohsumi, Y., Novel system for monitoring autophagy in the yeast Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 210 (1995), 126–132.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.210
, pp. 126-132
-
-
Noda, T.1
Matsuura, A.2
Wada, Y.3
Ohsumi, Y.4
-
29
-
-
84891745088
-
Historical landmarks of autophagy research
-
Ohsumi, Y., Historical landmarks of autophagy research. Cell Res. 24 (2014), 9–23.
-
(2014)
Cell Res.
, vol.24
, pp. 9-23
-
-
Ohsumi, Y.1
-
30
-
-
84893439181
-
Early steps in autophagy depend on direct phosphorylation of Atg9 by the Atg1 kinase
-
Papinski, D., Schuschnig, M., Reiter, W., Wilhelm, L., Barnes, C.A., Maiolica, A., Hansmann, I., Pfaffenwimmer, T., Kijanska, M., Stoffel, I., et al. Early steps in autophagy depend on direct phosphorylation of Atg9 by the Atg1 kinase. Mol. Cell 53 (2014), 471–483.
-
(2014)
Mol. Cell
, vol.53
, pp. 471-483
-
-
Papinski, D.1
Schuschnig, M.2
Reiter, W.3
Wilhelm, L.4
Barnes, C.A.5
Maiolica, A.6
Hansmann, I.7
Pfaffenwimmer, T.8
Kijanska, M.9
Stoffel, I.10
-
31
-
-
84871581862
-
Architecture of the Atg17 complex as a scaffold for autophagosome biogenesis
-
Ragusa, M.J., Stanley, R.E., Hurley, J.H., Architecture of the Atg17 complex as a scaffold for autophagosome biogenesis. Cell 21 (2012), 1501–1512.
-
(2012)
Cell
, vol.21
, pp. 1501-1512
-
-
Ragusa, M.J.1
Stanley, R.E.2
Hurley, J.H.3
-
32
-
-
84866122688
-
Autophagy modulation as a potential therapeutic target for diverse diseases
-
Rubinsztein, D.C., Codogno, P., Levine, B., Autophagy modulation as a potential therapeutic target for diverse diseases. Nat. Rev. Drug Discov. 11 (2012), 709–730.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 709-730
-
-
Rubinsztein, D.C.1
Codogno, P.2
Levine, B.3
-
33
-
-
65449186232
-
Atg17 recruits Atg9 to organize the pre-autophagosomal structure
-
Sekito, T., Kawamata, T., Ichikawa, R., Suzuki, K., Ohsumi, Y., Atg17 recruits Atg9 to organize the pre-autophagosomal structure. Genes Cells 14 (2009), 525–538.
-
(2009)
Genes Cells
, vol.14
, pp. 525-538
-
-
Sekito, T.1
Kawamata, T.2
Ichikawa, R.3
Suzuki, K.4
Ohsumi, Y.5
-
34
-
-
0035503594
-
The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation
-
Suzuki, K., Kirisako, T., Kamada, Y., Mizushima, N., Noda, T., Ohsumi, Y., The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation. EMBO J. 20 (2001), 5971–5981.
-
(2001)
EMBO J.
, vol.20
, pp. 5971-5981
-
-
Suzuki, K.1
Kirisako, T.2
Kamada, Y.3
Mizushima, N.4
Noda, T.5
Ohsumi, Y.6
-
35
-
-
84925307913
-
Atg13 HORMA domain recruits Atg9 vesicles during autophagosome formation
-
Suzuki, S.W., Yamamoto, H., Oikawa, Y., Kondo-Kakuta, C., Kimura, Y., Hirano, H., Ohsumi, Y., Atg13 HORMA domain recruits Atg9 vesicles during autophagosome formation. Proc. Natl. Acad. Sci. USA 112 (2015), 3350–3355.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. 3350-3355
-
-
Suzuki, S.W.1
Yamamoto, H.2
Oikawa, Y.3
Kondo-Kakuta, C.4
Kimura, Y.5
Hirano, H.6
Ohsumi, Y.7
-
36
-
-
84865814021
-
Guide to video recording of structure dynamics and dynamic processes of proteins by high-speed atomic force microscopy
-
Uchihashi, T., Kodera, N., Ando, T., Guide to video recording of structure dynamics and dynamic processes of proteins by high-speed atomic force microscopy. Nat. Protoc. 7 (2012), 1193–1206.
-
(2012)
Nat. Protoc.
, vol.7
, pp. 1193-1206
-
-
Uchihashi, T.1
Kodera, N.2
Ando, T.3
-
37
-
-
84876221513
-
Higher-order assemblies in a new paradigm of signal transduction
-
Wu, H., Higher-order assemblies in a new paradigm of signal transduction. Cell 153 (2013), 287–292.
-
(2013)
Cell
, vol.153
, pp. 287-292
-
-
Wu, H.1
-
38
-
-
84864991509
-
Atg9 vesicles are an important membrane source during early steps of autophagosome formation
-
Yamamoto, H., Kakuta, S., Watanabe, T.M., Kitamura, A., Sekito, T., Kondo-Kakuta, C., Ichikawa, R., Kinjo, M., Ohsumi, Y., Atg9 vesicles are an important membrane source during early steps of autophagosome formation. J. Cell Biol. 198 (2012), 219–233.
-
(2012)
J. Cell Biol.
, vol.198
, pp. 219-233
-
-
Yamamoto, H.1
Kakuta, S.2
Watanabe, T.M.3
Kitamura, A.4
Sekito, T.5
Kondo-Kakuta, C.6
Ichikawa, R.7
Kinjo, M.8
Ohsumi, Y.9
-
39
-
-
80051692531
-
An Atg13 protein-mediated self-association of the Atg1 protein kinase is important for the induction of autophagy
-
Yeh, Y.Y., Shah, K.H., Herman, P.K., An Atg13 protein-mediated self-association of the Atg1 protein kinase is important for the induction of autophagy. J. Biol. Chem. 286 (2011), 28931–28939.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 28931-28939
-
-
Yeh, Y.Y.1
Shah, K.H.2
Herman, P.K.3
|