메뉴 건너뛰기




Volumn 53, Issue 2, 2016, Pages 677-691

Modulation of Amyloid-β1-40 Transport by ApoA1 and ApoJ Across an in vitro Model of the Blood-Brain Barrier

Author keywords

Amyloid beta; ApoA1; ApoJ; Apolipoprotein; Blood brain barrier; Endothelial cells

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; APOLIPOPROTEIN A1; CLUSTERIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; THIOFLAVINE; AMYLOID BETA PROTEIN; APOA1 PROTEIN, HUMAN; CLU PROTEIN, HUMAN; MESSENGER RNA; PEPTIDE FRAGMENT; PLATELET ENDOTHELIAL CELL ADHESION MOLECULE 1; PROTEIN ZO1; TJP1 PROTEIN, HUMAN;

EID: 84979284139     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-150976     Document Type: Article
Times cited : (47)

References (60)
  • 1
    • 0034075450 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy: An overview
    • Yamada M (2000) Cerebral amyloid angiopathy: An overview. Neuropathology 20, 8-22.
    • (2000) Neuropathology , vol.20 , pp. 8-22
    • Yamada, M.1
  • 2
    • 27944461049 scopus 로고    scopus 로고
    • Sporadic cerebral amyloid angiopathy: Pathology, clinical implications, and possible pathomechanisms
    • Attems J (2005) Sporadic cerebral amyloid angiopathy: Pathology, clinical implications, and possible pathomechanisms. Neuropathology 110, 345-359.
    • (2005) Neuropathology , vol.110 , pp. 345-359
    • Attems, J.1
  • 4
    • 67349142021 scopus 로고    scopus 로고
    • Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease
    • Bell RD, Zlokovic BV (2009) Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease. Acta Neuropathol 118, 103-113.
    • (2009) Acta Neuropathol , vol.118 , pp. 103-113
    • Bell, R.D.1    Zlokovic, B.V.2
  • 5
    • 84893558854 scopus 로고    scopus 로고
    • Amyloid-peptides, Alzheimer's disease and the blood-brain barrier
    • Gosselet F, Saint-Pol J, Candela P, FenartL(2013) Amyloid-peptides, Alzheimer's disease and the blood-brain barrier. Curr Alzheimer Res 10, 1015-1033.
    • (2013) Curr Alzheimer Res , vol.10 , pp. 1015-1033
    • Gosselet, F.1    Saint-Pol, J.2    Candela, P.3    Fenart, L.4
  • 9
    • 34247506244 scopus 로고    scopus 로고
    • Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteinsEand J in the mouse central nervous system
    • Bell RD, Sagare AP, Friedman AE, Bedi GS, Holtzman DM, Deane R, Zlokovic BV (2007) Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteinsEand J in the mouse central nervous system. J Cereb Blood Flow Metab 27, 909-918.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 909-918
    • Bell, R.D.1    Sagare, A.P.2    Friedman, A.E.3    Bedi, G.S.4    Holtzman, D.M.5    Deane, R.6    Zlokovic, B.V.7
  • 10
    • 78650659385 scopus 로고    scopus 로고
    • Apicalto-basolateral transport of amyloid-peptides through blood-brain barrier cells is mediated by the receptor for advanced glycation end-products and is restricted by P-glycoprotein
    • Candela P, Gosselet F, Saint-Pol J, Sevin E, Boucau MC, Boulanger E, Cecchelli R, Fenart L (2010) Apicalto-basolateral transport of amyloid-peptides through blood-brain barrier cells is mediated by the receptor for advanced glycation end-products and is restricted by P-glycoprotein. J Alzheimers Dis 22, 849-859.
    • (2010) J Alzheimers Dis , vol.22 , pp. 849-859
    • Candela, P.1    Gosselet, F.2    Saint-Pol, J.3    Sevin, E.4    Boucau, M.C.5    Boulanger, E.6    Cecchelli, R.7    Fenart, L.8
  • 11
    • 2542475986 scopus 로고    scopus 로고
    • Clearing amyloid through the bloodbrain barrier
    • Zlokovic BV (2004) Clearing amyloid through the bloodbrain barrier. J Neurochem 89, 807-811.
    • (2004) J Neurochem , vol.89 , pp. 807-811
    • Zlokovic, B.V.1
  • 12
    • 77951078680 scopus 로고    scopus 로고
    • Restoring bloodbrain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease
    • Hartz AM, Miller DS, Bauer B (2010) Restoring bloodbrain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease. Mol Pharmacol 77, 715-723.
    • (2010) Mol Pharmacol , vol.77 , pp. 715-723
    • Hartz, A.M.1    Miller, D.S.2    Bauer, B.3
  • 13
    • 84879495507 scopus 로고    scopus 로고
    • The role of ABCB1 and ABCA1 in beta-amyloid clearance at the neurovascular unit in Alzheimer's disease
    • Elali A, Rivest S (2013) The role of ABCB1 and ABCA1 in beta-amyloid clearance at the neurovascular unit in Alzheimer's disease. Front Physiol 4, 45.
    • (2013) Front Physiol , vol.4 , pp. 45
    • Elali, A.1    Rivest, S.2
  • 15
    • 0028991404 scopus 로고
    • Apolipoprotein e epsilon 4 and cerebral hemorrhage associated with amyloid angiopathy
    • Greenberg SM, Rebeck GW, Vonsattel JP, Gomez-Isla T, Hyman BT (1995) Apolipoprotein E epsilon 4 and cerebral hemorrhage associated with amyloid angiopathy. Ann Neurol 38, 254-259.
    • (1995) Ann Neurol , vol.38 , pp. 254-259
    • Greenberg, S.M.1    Rebeck, G.W.2    Vonsattel, J.P.3    Gomez-Isla, T.4    Hyman, B.T.5
  • 19
    • 0028609448 scopus 로고
    • The soluble form of Alzheimer's amyloid beta protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma
    • Koudinov AR, Matsubara E, Frangione B, Ghiso J (1994) The soluble form of Alzheimer's amyloid beta protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma. Biochem Biophys Res Commun 205, 1164-1171.
    • (1994) Biochem Biophys Res Commun , vol.205 , pp. 1164-1171
    • Koudinov, A.R.1    Matsubara, E.2    Frangione, B.3    Ghiso, J.4
  • 20
    • 0032559575 scopus 로고    scopus 로고
    • Alzheimer's amyloid beta interaction with normal human plasma high density lipoprotein: Association with apolipoprotein and lipids
    • Koudinov AR, Berezov TT, Kumar A, Koudinova NV (1998) Alzheimer's amyloid beta interaction with normal human plasma high density lipoprotein: Association with apolipoprotein and lipids. Clin Chim Acta 270, 75-84.
    • (1998) Clin Chim Acta , vol.270 , pp. 75-84
    • Koudinov, A.R.1    Berezov, T.T.2    Kumar, A.3    Koudinova, N.V.4
  • 22
    • 0028921915 scopus 로고
    • Characterization of apolipoprotein J-Alzheimer's A beta interaction
    • Matsubara E, Frangione B, Ghiso J (1995) Characterization of apolipoprotein J-Alzheimer's A beta interaction. J Biol Chem 270, 7563-7567.
    • (1995) J Biol Chem , vol.270 , pp. 7563-7567
    • Matsubara, E.1    Frangione, B.2    Ghiso, J.3
  • 23
    • 0029081399 scopus 로고
    • Conformational mimicry in Alzheimer's disease. Role of apolipoproteins in amyloidogenesis
    • Wisniewski T, Golabek AA, Kida E,Wisniewski KE, Frangione B (1995) Conformational mimicry in Alzheimer's disease. Role of apolipoproteins in amyloidogenesis. Am J Pathol 147, 238-244.
    • (1995) Am J Pathol , vol.147 , pp. 238-244
    • Wisniewski, T.1    Golabek, A.A.2    Kida, E.3    Wisniewski, K.E.4    Frangione, B.5
  • 24
    • 0030001328 scopus 로고    scopus 로고
    • Brain expression of apolipoproteins E, J, and A-I in Alzheimer's disease
    • Harr SD, Uint L, Hollister R, Hyman BT, Mendez AJ (1996) Brain expression of apolipoproteins E, J, and A-I in Alzheimer's disease. J Neurochem 66, 2429-2435.
    • (1996) J Neurochem , vol.66 , pp. 2429-2435
    • Harr, S.D.1    Uint, L.2    Hollister, R.3    Hyman, B.T.4    Mendez, A.J.5
  • 25
    • 0035957222 scopus 로고    scopus 로고
    • Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicity
    • Koldamova RP, Lefterov IM, Lefterova MI, Lazo JS (2001) Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicity. Biochemistry 40, 3553-3560.
    • (2001) Biochemistry , vol.40 , pp. 3553-3560
    • Koldamova, R.P.1    Lefterov, I.M.2    Lefterova, M.I.3    Lazo, J.S.4
  • 27
    • 30844472909 scopus 로고    scopus 로고
    • IgGassisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor
    • Deane R, Sagare A, Hamm K, Parisi M, LaRue B, Guo H, Wu Z, Holtzman DM, Zlokovic BV (2005) IgGassisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor. J Neurosci 25, 11495-11503.
    • (2005) J Neurosci , vol.25 , pp. 11495-11503
    • Deane, R.1    Sagare, A.2    Hamm, K.3    Parisi, M.4    LaRue, B.5    Guo, H.6    Wu, Z.7    Holtzman, D.M.8    Zlokovic, B.V.9
  • 29
    • 84878494268 scopus 로고    scopus 로고
    • Oxysterols decrease apical-to-basolateral transport of Aß peptides via an ABCB1-mediated process in an in vitro Blood-brain barrier model constituted of bovine brain capillary endothelial cells
    • Saint-Pol J, Candela P, Boucau MC, Fenart L, Gosselet F (2013) Oxysterols decrease apical-to-basolateral transport of Aß peptides via an ABCB1-mediated process in an in vitro Blood-brain barrier model constituted of bovine brain capillary endothelial cells. Brain Res 1517, 1-15.
    • (2013) Brain Res , vol.1517 , pp. 1-15
    • Saint-Pol, J.1    Candela, P.2    Boucau, M.C.3    Fenart, L.4    Gosselet, F.5
  • 30
    • 78651497015 scopus 로고    scopus 로고
    • Characterization and use of human brain microvascular endothelial cells to examine-amyloid exchange in the blood-brain barrier
    • Bachmeier C, Mullan M, Paris D (2010) Characterization and use of human brain microvascular endothelial cells to examine-amyloid exchange in the blood-brain barrier. Cytotechnology 62, 519-529.
    • (2010) Cytotechnology , vol.62 , pp. 519-529
    • Bachmeier, C.1    Mullan, M.2    Paris, D.3
  • 35
    • 33747652958 scopus 로고    scopus 로고
    • Distinct early folding and aggregation properties of Alzheimer amyloid-beta peptides Abeta40 and Abeta42: Stable trimer or tetramer formation by Abeta42
    • Chen YR, Glabe CG (2006) Distinct early folding and aggregation properties of Alzheimer amyloid-beta peptides Abeta40 and Abeta42: Stable trimer or tetramer formation by Abeta42. J Biol Chem 281, 24414-24422.
    • (2006) J Biol Chem , vol.281 , pp. 24414-24422
    • Chen, Y.R.1    Glabe, C.G.2
  • 37
    • 0029920929 scopus 로고    scopus 로고
    • Glycoprotein 330/megalin: Probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers
    • Zlokovic BV,Martel CL, Matsubara E, McComb JG, Zheng G, McCluskey RT, Frangione B, Ghiso J (1996) Glycoprotein 330/megalin: Probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers. Proc Natl Acad Sci U S A 93, 4229-4234.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 4229-4234
    • Zlokovic, B.V.1    Martel, C.L.2    Matsubara, E.3    McComb, J.G.4    Zheng, G.5    McCluskey, R.T.6    Frangione, B.7    Ghiso, J.8
  • 38
    • 0030779128 scopus 로고    scopus 로고
    • Isoform-specific effects of apolipoproteins E2, E3, and E4 on cerebral capillary sequestration and bloodbrain barrier transport of circulating Alzheimer's amyloid beta
    • Martel CL, Mackic JB, Matsubara E, Governale S, Miguel C, Miao W, McComb JG, Frangione B, Ghiso J, Zlokovic BV (1997) Isoform-specific effects of apolipoproteins E2, E3, and E4 on cerebral capillary sequestration and bloodbrain barrier transport of circulating Alzheimer's amyloid beta. J Neurochem 69, 1995-2004.
    • (1997) J Neurochem , vol.69 , pp. 1995-2004
    • Martel, C.L.1    Mackic, J.B.2    Matsubara, E.3    Governale, S.4    Miguel, C.5    Miao, W.6    McComb, J.G.7    Frangione, B.8    Ghiso, J.9    Zlokovic, B.V.10
  • 40
    • 36448976927 scopus 로고    scopus 로고
    • Cerebral clearance of human amyloid-beta peptide (1-40) across the blood-brain barrier is reduced by self-aggregation and formation of low-density lipoprotein receptor-related protein-1 ligand complexes
    • Ito S, Ohtsuki S, Kamiie J, Nezu Y, Terasaki T (2007) Cerebral clearance of human amyloid-beta peptide (1-40) across the blood-brain barrier is reduced by self-aggregation and formation of low-density lipoprotein receptor-related protein-1 ligand complexes. J Neurochem 103, 2482-2490.
    • (2007) J Neurochem , vol.103 , pp. 2482-2490
    • Ito, S.1    Ohtsuki, S.2    Kamiie, J.3    Nezu, Y.4    Terasaki, T.5
  • 41
    • 84896726518 scopus 로고    scopus 로고
    • ApoE and A in Alzheimer's disease: Accidental encounters or partners?
    • Kanekiyo T, Xu H, Bu G (2014) ApoE and A- in Alzheimer's disease: Accidental encounters or partners? Neuron 81, 740-754.
    • (2014) Neuron , vol.81 , pp. 740-754
    • Kanekiyo, T.1    Xu, H.2    Bu, G.3
  • 42
    • 0027186334 scopus 로고
    • The cerebrospinalfluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex
    • Ghiso J, Matsubara E,KoudinovA, Choi-Miura NH, Tomita M, Wisniewski T, Frangione B (1993) The cerebrospinalfluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex. Biochem J 293, 27-30.
    • (1993) Biochem J , vol.293 , pp. 27-30
    • Ghiso, J.1    Matsubara, E.2    Koudinov, A.3    Choi-Miura, N.H.4    Tomita, M.5    Wisniewski, T.6    Frangione, B.7
  • 43
    • 2542485364 scopus 로고    scopus 로고
    • Uptake and transport of high-density lipoprotein (HDL) and HDL-associated alpha-tocopherol by an in vitro blood-brain barrier model
    • Balazs Z, Panzenboeck U, Hammer A, Sovic A, Quehenberger O, Malle E, Sattler W (2004) Uptake and transport of high-density lipoprotein (HDL) and HDL-associated alpha-tocopherol by an in vitro blood-brain barrier model. J Neurochem 89, 939-950.
    • (2004) J Neurochem , vol.89 , pp. 939-950
    • Balazs, Z.1    Panzenboeck, U.2    Hammer, A.3    Sovic, A.4    Quehenberger, O.5    Malle, E.6    Sattler, W.7
  • 44
    • 0035083555 scopus 로고    scopus 로고
    • Cholesterol metabolism in the brain
    • Dietschy JM, Turley SD (2001) Cholesterol metabolism in the brain. Curr Opin Lipidol 12, 105-112.
    • (2001) Curr Opin Lipidol , vol.12 , pp. 105-112
    • Dietschy, J.M.1    Turley, S.D.2
  • 47
    • 58149131290 scopus 로고    scopus 로고
    • Transcriptional profiles of receptors and transporters involved in brain cholesterol homeostasis at the blood-brain barrier: Use of an in vitro model
    • Gosselet F, Candela P, Sevin E, Berezowski V, Cecchelli R, Fenart L (2009) Transcriptional profiles of receptors and transporters involved in brain cholesterol homeostasis at the blood-brain barrier: Use of an in vitro model. Brain Res 1249, 34-42.
    • (2009) Brain Res , vol.1249 , pp. 34-42
    • Gosselet, F.1    Candela, P.2    Sevin, E.3    Berezowski, V.4    Cecchelli, R.5    Fenart, L.6
  • 48
    • 84893833082 scopus 로고    scopus 로고
    • Differences in amyloid-clearance across mouse and human blood-brain barrier models: Kinetic analysis and mechanistic modeling
    • Qosa H, Abuasal BS, Romero IA,Weksler B, Couraud PO, Keller JN, Kaddoumi A (2014) Differences in amyloid-clearance across mouse and human blood-brain barrier models: Kinetic analysis and mechanistic modeling. Neuropharmacology 79, 668-678.
    • (2014) Neuropharmacology , vol.79 , pp. 668-678
    • Qosa, H.1    Abuasal, B.S.2    Romero, I.A.3    Weksler, B.4    Couraud, P.O.5    Keller, J.N.6    Kaddoumi, A.7
  • 49
    • 84919632560 scopus 로고    scopus 로고
    • In vitro discrimination of the role of LRP1 at the BBB cellular level: Focus on brain capillary endothelial cells and brain pericytes
    • Candela P, Saint-Pol J, Kuntz M, Boucau MC, Lamartiniere Y, Gosselet F, Fenart L (2015) In vitro discrimination of the role of LRP1 at the BBB cellular level: Focus on brain capillary endothelial cells and brain pericytes. Brain Res 1594, 15-26.
    • (2015) Brain Res , vol.1594 , pp. 15-26
    • Candela, P.1    Saint-Pol, J.2    Kuntz, M.3    Boucau, M.C.4    Lamartiniere, Y.5    Gosselet, F.6    Fenart, L.7
  • 51
    • 53549086409 scopus 로고    scopus 로고
    • Evidence for altered LRP/RAGE expression in Alzheimer lesion pathogenesis
    • Jeynes B, Provias J (2008) Evidence for altered LRP/RAGE expression in Alzheimer lesion pathogenesis. Curr Alzheimer Res 5, 432-437.
    • (2008) Curr Alzheimer Res , vol.5 , pp. 432-437
    • Jeynes, B.1    Provias, J.2
  • 53
    • 0029643560 scopus 로고
    • Marked decrease of plasma apolipoprotein AI and AII in Japanese patients with late-onset non-familial Alzheimer's disease
    • Kawano M,Kawakami M, Otsuka M,Yashima H,Yaginuma T, UekiA(1995) Marked decrease of plasma apolipoprotein AI and AII in Japanese patients with late-onset non-familial Alzheimer's disease. Clin Chim Acta 239, 209-211.
    • (1995) Clin Chim Acta , vol.239 , pp. 209-211
    • Kawano, M.1    Kawakami, M.2    Otsuka, M.3    Yashima, H.4    Yaginuma, T.5    Ueki, A.6
  • 54
    • 34247103970 scopus 로고    scopus 로고
    • The relation between apolipoprotein A-I and dementia: The Honolulu-Asia aging study
    • Saczynski JS, White L, Peila RL, Rodriguez BL, Launer LJ (2007) The relation between apolipoprotein A-I and dementia: The Honolulu-Asia aging study. Am J Epidemiol 165, 985-992.
    • (2007) Am J Epidemiol , vol.165 , pp. 985-992
    • Saczynski, J.S.1    White, L.2    Peila, R.L.3    Rodriguez, B.L.4    Launer, L.J.5
  • 55
    • 0034594467 scopus 로고    scopus 로고
    • Decreased high-density lipoprotein cholesterol and serum apolipoprotein AI concentrations are highly correlated with the severity of Alzheimer's disease
    • Merched A, Xia Y, Visvikis S, Serot JM, Siest G (2000) Decreased high-density lipoprotein cholesterol and serum apolipoprotein AI concentrations are highly correlated with the severity of Alzheimer's disease. Neurobiol Aging 21, 27-30.
    • (2000) Neurobiol Aging , vol.21 , pp. 27-30
    • Merched, A.1    Xia, Y.2    Visvikis, S.3    Serot, J.M.4    Siest, G.5
  • 56
    • 78449232720 scopus 로고    scopus 로고
    • Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice
    • Lefterov I, Fitz NF, Cronican AA, Fogg A, Lefterov P, Kodali R, Wetzel R, Koldamova R (2010) Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice. J Biol Chem 285, 36945-36957.
    • (2010) J Biol Chem , vol.285 , pp. 36945-36957
    • Lefterov, I.1    Fitz, N.F.2    Cronican, A.A.3    Fogg, A.4    Lefterov, P.5    Kodali, R.6    Wetzel, R.7    Koldamova, R.8
  • 57
    • 78449255602 scopus 로고    scopus 로고
    • Overexpression of human apolipoprotein A-I preserves cognitive function and attenuates neuroinflammation and cerebral amyloid angiopathy in a mouse model of Alzheimer disease
    • Lewis TL, Cao D, Lu H, Mans RA, Su YR, Jungbauer L, Linton MF, Fazio S, LaDu MJ, Li L (2010) Overexpression of human apolipoprotein A-I preserves cognitive function and attenuates neuroinflammation and cerebral amyloid angiopathy in a mouse model of Alzheimer disease. J Biol Chem 285, 36958-36968.
    • (2010) J Biol Chem , vol.285 , pp. 36958-36968
    • Lewis, T.L.1    Cao, D.2    Lu, H.3    Mans, R.A.4    Su, Y.R.5    Jungbauer, L.6    Linton, M.F.7    Fazio, S.8    LaDu, M.J.9    Li, L.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.