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Volumn 7, Issue 3, 2016, Pages

Plasmodium falciparum histidine-rich protein II compromises brain endothelial barriers and may promote cerebral malaria pathogenesis

Author keywords

[No Author keywords available]

Indexed keywords

HISTIDINE RICH PROTEIN II; INFLAMMASOME; REGULATOR PROTEIN; UNCLASSIFIED DRUG; HISTIDINE-RICH PROTEINS; PROTEIN; VIRULENCE FACTOR;

EID: 84979036990     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00617-16     Document Type: Article
Times cited : (58)

References (69)
  • 1
    • 0037034017 scopus 로고    scopus 로고
    • The pathogenic basis of malaria
    • Miller LH, Baruch DI, Marsh K, Doumbo OK. 2002. The pathogenic basis of malaria. Nature 415:673-679. http://dx.doi.org/10.1038/415673a.
    • (2002) Nature , vol.415 , pp. 673-679
    • Miller, L.H.1    Baruch, D.I.2    Marsh, K.3    Doumbo, O.K.4
  • 2
    • 0021884874 scopus 로고
    • Human cerebral malaria. A quantitative ultrastructural analysis of parasitized erythrocyte sequestration
    • MacPherson GG, Warrell MJ, White NJ, Looareesuwan S, Warrell DA. 1985. Human cerebral malaria. A quantitative ultrastructural analysis of parasitized erythrocyte sequestration. Am J Pathol 119:385-401.
    • (1985) Am J Pathol , vol.119 , pp. 385-401
    • MacPherson, G.G.1    Warrell, M.J.2    White, N.J.3    Looareesuwan, S.4    Warrell, D.A.5
  • 3
    • 27744563110 scopus 로고    scopus 로고
    • Pathogenesis, clinical features, and neurological outcome of cerebral malaria
    • Idro R, Jenkins NE, Newton CR. 2005. Pathogenesis, clinical features, and neurological outcome of cerebral malaria. Lancet Neurol 4:827-840. http://dx.doi.org/10.1016/S1474-4422(05)70247-7.
    • (2005) Lancet Neurol , vol.4 , pp. 827-840
    • Idro, R.1    Jenkins, N.E.2    Newton, C.R.3
  • 4
    • 0025080932 scopus 로고
    • Neurological sequelae of cerebral malaria in children
    • Brewster DR, Kwiatkowski D, White NJ. 1990. Neurological sequelae of cerebral malaria in children. Lancet 336:1039-1043. http://dx.doi.org/10.1016/0140-6736(90)92498-7.
    • (1990) Lancet , vol.336 , pp. 1039-1043
    • Brewster, D.R.1    Kwiatkowski, D.2    White, N.J.3
  • 6
    • 78650257716 scopus 로고    scopus 로고
    • The "hidden" burden of malaria: Cognitive impairment following infection
    • Fernando SD, Rodrigo C, Rajapakse S. 2010. The "hidden" burden of malaria: cognitive impairment following infection. Malar J 9:366. http://dx.doi.org/10.1186/1475-2875-9-366.
    • (2010) Malar J , vol.9 , pp. 366
    • Fernando, S.D.1    Rodrigo, C.2    Rajapakse, S.3
  • 10
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
    • Kawai T, Akira S. 2010. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 11: 373-384. http://dx.doi.org/10.1038/ni.1863.
    • (2010) Nat Immunol , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 11
    • 78651106773 scopus 로고    scopus 로고
    • Review: Molecular pathogenesis of blood-brain barrier breakdown in acute brain injury
    • Nag S, Kapadia A, Stewart DJ. 2011. Review: molecular pathogenesis of blood-brain barrier breakdown in acute brain injury. Neuropathol Appl Neurobiol 37:3-23. http://dx.doi.org/10.1111/j.1365-2990.2010.01138.x.
    • (2011) Neuropathol Appl Neurobiol , vol.37 , pp. 3-23
    • Nag, S.1    Kapadia, A.2    Stewart, D.J.3
  • 12
    • 0022994181 scopus 로고
    • Secretion of a malarial histidine-rich protein (Pf HRP II) from Plasmodium falciparum-infected erythrocytes
    • Howard RJ, Uni S, Aikawa M, Aley SB, Leech JH, Lew AM, Wellems TE, Rener J, Taylor DW. 1986. Secretion of a malarial histidine-rich protein (Pf HRP II) from Plasmodium falciparum-infected erythrocytes. J Cell Biol 103:1269-1277. http://dx.doi.org/10.1083/jcb.103.4.1269.
    • (1986) J Cell Biol , vol.103 , pp. 1269-1277
    • Howard, R.J.1    Uni, S.2    Aikawa, M.3    Aley, S.B.4    Leech, J.H.5    Lew, A.M.6    Wellems, T.E.7    Rener, J.8    Taylor, D.W.9
  • 13
    • 0001952505 scopus 로고
    • Homologous genes encode two distinct histidine-rich proteins in a cloned isolate of Plasmodium falciparum
    • Wellems TE, Howard RJ. 1986. Homologous genes encode two distinct histidine-rich proteins in a cloned isolate of Plasmodium falciparum. Proc Natl Acad Sci U S A 83:6065-6069. http://dx.doi.org/10.1073/pnas.83.16.6065.
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 6065-6069
    • Wellems, T.E.1    Howard, R.J.2
  • 14
    • 0030045312 scopus 로고    scopus 로고
    • Plasmodium hemozoin formation mediated by histidine-rich proteins
    • Sullivan DJ, Jr, Gluzman IY, Goldberg DE. 1996. Plasmodium hemozoin formation mediated by histidine-rich proteins. Science 271:219-222. http://dx.doi.org/10.1126/science.271.5246.219.
    • (1996) Science , vol.271 , pp. 219-222
    • Sullivan Jr, D.J.1    Gluzman, I.Y.2    Goldberg, D.E.3
  • 15
    • 0037177888 scopus 로고    scopus 로고
    • Plasmodium falciparum histidine-rich protein-2 (PfHRP2) modulates the redox activity of ferri-protoporphyrin IX (FePPIX): Peroxidaselike activity of the PfHRP2-FePPIX complex
    • Mashima R, Tilley L, Siomos MA, Papalexis V, Raftery MJ, Stocker R. 2002. Plasmodium falciparum histidine-rich protein-2 (PfHRP2) modulates the redox activity of ferri-protoporphyrin IX (FePPIX): peroxidaselike activity of the PfHRP2-FePPIX complex. J Biol Chem 277: 14514-14520. http://dx.doi.org/10.1074/jbc.M109386200.
    • (2002) J Biol Chem , vol.277 , pp. 14514-14520
    • Mashima, R.1    Tilley, L.2    Siomos, M.A.3    Papalexis, V.4    Raftery, M.J.5    Stocker, R.6
  • 16
    • 0037651040 scopus 로고    scopus 로고
    • Plasmodium falciparum histidine-rich protein II binds to actin, phosphatidylinositol 4,5-bisphosphate and erythrocyte ghosts in a pH-dependent manner and undergoes coil-to-helix transitions in anionic micelles
    • Benedetti CE, Kobarg J, Pertinhez TA, Gatti RM, de Souza ON, Spisni A, Meneghini R. 2003. Plasmodium falciparum histidine-rich protein II binds to actin, phosphatidylinositol 4,5-bisphosphate and erythrocyte ghosts in a pH-dependent manner and undergoes coil-to-helix transitions in anionic micelles. Mol Biochem Parasitol 128:157-166. http://dx.doi.org/10.1016/S0166-6851(03)00057-4.
    • (2003) Mol Biochem Parasitol , vol.128 , pp. 157-166
    • Benedetti, C.E.1    Kobarg, J.2    Pertinhez, T.A.3    Gatti, R.M.4    de Souza, O.N.5    Spisni, A.6    Meneghini, R.7
  • 17
    • 79959476157 scopus 로고    scopus 로고
    • Inhibition of antithrombin by Plasmodium falciparum histidine-rich protein II
    • Ndonwi M, Burlingame OO, Miller AS, Tollefsen DM, Broze GJ, Jr, Goldberg DE. 2011. Inhibition of antithrombin by Plasmodium falciparum histidine-rich protein II. Blood 117:6347-6354. http://dx.doi.org/10.1182/blood-2010-12-326876.
    • (2011) Blood , vol.117 , pp. 6347-6354
    • Ndonwi, M.1    Burlingame, O.O.2    Miller, A.S.3    Tollefsen, D.M.4    Broze Jr, G.J.5    Goldberg, D.E.6
  • 19
    • 0025850368 scopus 로고
    • Identification of Plasmodium falciparum histidine-rich protein 2 in the plasma of humans with malaria
    • Parra ME, Evans CB, Taylor DW. 1991. Identification of Plasmodium falciparum histidine-rich protein 2 in the plasma of humans with malaria. J Clin Microbiol 29:1629-1634.
    • (1991) J Clin Microbiol , vol.29 , pp. 1629-1634
    • Parra, M.E.1    Evans, C.B.2    Taylor, D.W.3
  • 22
    • 84873029464 scopus 로고    scopus 로고
    • Plasma concentrations of parasite histidine-rich protein 2 distinguish between retinopathy-positive and retinopathy-negative cerebral malaria in Malawian children
    • Seydel KB, Fox LL, Glover SJ, Reeves MJ, Pensulo P, Muiruri A, Mpakiza A, Molyneux ME, Taylor TE. 2012. Plasma concentrations of parasite histidine-rich protein 2 distinguish between retinopathy-positive and retinopathy-negative cerebral malaria in Malawian children. J Infect Dis 206:309-318. http://dx.doi.org/10.1093/infdis/jis371.
    • (2012) J Infect Dis , vol.206 , pp. 309-318
    • Seydel, K.B.1    Fox, L.L.2    Glover, S.J.3    Reeves, M.J.4    Pensulo, P.5    Muiruri, A.6    Mpakiza, A.7    Molyneux, M.E.8    Taylor, T.E.9
  • 24
    • 84880233869 scopus 로고    scopus 로고
    • Histidine-rich protein 2 plasma levels predict progression to cerebral malaria in Malawian children with Plas-modium falciparum infection
    • Fox LL, Taylor TE, Pensulo P, Liomba A, Mpakiza A, Varela A, Glover SJ, Reeves MJ, Seydel KB. 2013. Histidine-rich protein 2 plasma levels predict progression to cerebral malaria in Malawian children with Plas-modium falciparum infection. J Infect Dis 208:500-503. http://dx.doi.org/10.1093/infdis/jit176.
    • (2013) J Infect Dis , vol.208 , pp. 500-503
    • Fox, L.L.1    Taylor, T.E.2    Pensulo, P.3    Liomba, A.4    Mpakiza, A.5    Varela, A.6    Glover, S.J.7    Reeves, M.J.8    Seydel, K.B.9
  • 25
    • 84893340214 scopus 로고    scopus 로고
    • Value of Plasmodium falciparum histidine-rich protein 2 level and malaria retinopathy in distinguishing cerebral malaria from other acute encephalopathies in Kenyan children
    • Kariuki SM, Gitau E, Gwer S, Karanja HK, Chengo E, Kazungu M, Urban BC, Newton CR. 2014. Value of Plasmodium falciparum histidine-rich protein 2 level and malaria retinopathy in distinguishing cerebral malaria from other acute encephalopathies in Kenyan children. J Infect Dis 209:600-609. http://dx.doi.org/10.1093/infdis/jit500.
    • (2014) J Infect Dis , vol.209 , pp. 600-609
    • Kariuki, S.M.1    Gitau, E.2    Gwer, S.3    Karanja, H.K.4    Chengo, E.5    Kazungu, M.6    Urban, B.C.7    Newton, C.R.8
  • 26
    • 77749309907 scopus 로고    scopus 로고
    • A large proportion of P. falciparum isolates in the Amazon region of Peru lack pfhrp2 and pfhrp3: Implications for malaria rapid diagnostic tests
    • Gamboa D, Ho MF, Bendezu J, Torres K, Chiodini PL, Barnwell JW, Incardona S, Perkins M, Bell D, McCarthy J, Cheng Q. 2010. A large proportion of P. falciparum isolates in the Amazon region of Peru lack pfhrp2 and pfhrp3: implications for malaria rapid diagnostic tests. PLoS One 5:e8091. http://dx.doi.org/10.1371/journal.pone.0008091.
    • (2010) PLoS One , vol.5
    • Gamboa, D.1    Ho, M.F.2    Bendezu, J.3    Torres, K.4    Chiodini, P.L.5    Barnwell, J.W.6    Incardona, S.7    Perkins, M.8    Bell, D.9    McCarthy, J.10    Cheng, Q.11
  • 28
    • 84868684282 scopus 로고    scopus 로고
    • Genetic deletion of HRP2 and HRP3 in Indian Plasmodium falciparum population and false negative malaria rapid diagnostic test
    • Kumar N, Pande V, Bhatt RM, Shah NK, Mishra N, Srivastava B, Valecha N, Anvikar AR. 2013. Genetic deletion of HRP2 and HRP3 in Indian Plasmodium falciparum population and false negative malaria rapid diagnostic test. Acta Trop 125:119-121. http://dx.doi.org/10.1016/j.actatropica.2012.09.015.
    • (2013) Acta Trop , vol.125 , pp. 119-121
    • Kumar, N.1    Pande, V.2    Bhatt, R.M.3    Shah, N.K.4    Mishra, N.5    Srivastava, B.6    Valecha, N.7    Anvikar, A.R.8
  • 29
    • 33947428432 scopus 로고    scopus 로고
    • Plasmodium falciparuminfected erythrocytes decrease the integrity of human blood-brain barrier endothelial cell monolayers
    • Tripathi AK, Sullivan DJ, Stins MF. 2007. Plasmodium falciparuminfected erythrocytes decrease the integrity of human blood-brain barrier endothelial cell monolayers. J Infect Dis 195:942-950. http://dx.doi.org/10.1086/512083.
    • (2007) J Infect Dis , vol.195 , pp. 942-950
    • Tripathi, A.K.1    Sullivan, D.J.2    Stins, M.F.3
  • 30
    • 84868249383 scopus 로고    scopus 로고
    • Immortalized human cerebral microvascular endothelial cells maintain the properties of primary cells in an in vitro model of immune migration across the blood brain barrier
    • Daniels BP, Cruz-Orengo L, Pasieka TJ, Couraud PO, Romero IA, Weksler B, Cooper JA, Doering TL, Klein RS. 2013. Immortalized human cerebral microvascular endothelial cells maintain the properties of primary cells in an in vitro model of immune migration across the blood brain barrier. J Neurosci Methods 212:173-179. http://dx.doi.org/10.1016/j.jneumeth.2012.10.001.
    • (2013) J Neurosci Methods , vol.212 , pp. 173-179
    • Daniels, B.P.1    Cruz-Orengo, L.2    Pasieka, T.J.3    Couraud, P.O.4    Romero, I.A.5    Weksler, B.6    Cooper, J.A.7    Doering, T.L.8    Klein, R.S.9
  • 32
    • 77955906264 scopus 로고    scopus 로고
    • The nuclear factor NF-kappaB pathway in inflammation
    • Lawrence T. 2009. The nuclear factor NF-kappaB pathway in inflammation. Cold Spring Harb Perspect Biol 1:a001651. http://dx.doi.org/10.1101/cshperspect.a001651.
    • (2009) Cold Spring Harb Perspect Biol , vol.1
    • Lawrence, T.1
  • 33
    • 63849258626 scopus 로고    scopus 로고
    • Asmall-molecule triptolide suppresses angiogenesis and invasion of human anaplastic thyroid carcinoma cells via down-regulation of the nuclear factor-kappa B pathway
    • Zhu W, Ou Y, Li Y, Xiao R, Shu M, Zhou Y, Xie J, He S, Qiu P, Yan G. 2009. Asmall-molecule triptolide suppresses angiogenesis and invasion of human anaplastic thyroid carcinoma cells via down-regulation of the nuclear factor-kappa B pathway. Mol Pharmacol 75:812-819. http://dx.doi.org/10.1124/mol.108.052605.
    • (2009) Mol Pharmacol , vol.75 , pp. 812-819
    • Zhu, W.1    Ou, Y.2    Li, Y.3    Xiao, R.4    Shu, M.5    Zhou, Y.6    Xie, J.7    He, S.8    Qiu, P.9    Yan, G.10
  • 34
    • 84899694806 scopus 로고    scopus 로고
    • NF-kappa B modulation is involved in celastrol induced human multiple myeloma cell apoptosis
    • Ni H, Zhao W, Kong X, Li H, Ouyang J. 2014. NF-kappa B modulation is involved in celastrol induced human multiple myeloma cell apoptosis. PLoS One 9:e95846. http://dx.doi.org/10.1371/journal.pone.0095846.
    • (2014) PLoS One , vol.9
    • Ni, H.1    Zhao, W.2    Kong, X.3    Li, H.4    Ouyang, J.5
  • 35
    • 20544474210 scopus 로고    scopus 로고
    • Pathogen recognition with Toll-like receptors
    • Kawai T, Akira S. 2005. Pathogen recognition with Toll-like receptors. Curr Opin Immunol 17:338-344. http://dx.doi.org/10.1016/j.coi.2005.02.007.
    • (2005) Curr Opin Immunol , vol.17 , pp. 338-344
    • Kawai, T.1    Akira, S.2
  • 37
    • 84882641298 scopus 로고    scopus 로고
    • Contrasting pediatric and adult cerebral malaria: The role of the endothelial barrier
    • Hawkes M, Elphinstone RE, Conroy AL, Kain KC. 2013. Contrasting pediatric and adult cerebral malaria: the role of the endothelial barrier. Virulence 4:543-555. http://dx.doi.org/10.4161/viru.25949.
    • (2013) Virulence , vol.4 , pp. 543-555
    • Hawkes, M.1    Elphinstone, R.E.2    Conroy, A.L.3    Kain, K.C.4
  • 38
    • 84987985154 scopus 로고    scopus 로고
    • Pathogenesis of cerebral malaria-inflammation and cytoadherence
    • Storm J, Craig AG. 2014. Pathogenesis of cerebral malaria-inflammation and cytoadherence. Front Cell Infect Microbiol 4:100. http://dx.doi.org/10.3389/fcimb.2014.00100.
    • (2014) Front Cell Infect Microbiol , vol.4 , pp. 100
    • Storm, J.1    Craig, A.G.2
  • 40
    • 46049087164 scopus 로고    scopus 로고
    • Cytoadherence characteristics to endothelial receptors ICAM-1 and CD36 of Plasmodium falciparum populations from severe and uncomplicated malaria cases
    • Cojean S, Jafari-Guemouri S, Le Bras J, Durand R. 2008. Cytoadherence characteristics to endothelial receptors ICAM-1 and CD36 of Plasmodium falciparum populations from severe and uncomplicated malaria cases. Parasite 15:163-169. http://dx.doi.org/10.1051/parasite/2008152163.
    • (2008) Parasite , vol.15 , pp. 163-169
    • Cojean, S.1    Jafari-Guemouri, S.2    Le Bras, J.3    Durand, R.4
  • 42
    • 0023616658 scopus 로고
    • Comparative analysis of the Plasmodium falciparum histidine-rich proteins HRP-I, HRP-II and HRP-III in malaria parasites of diverse origin
    • Rock EP, Marsh K, Saul AJ, Wellems TE, Taylor DW, Maloy WL, Howard RJ. 1987. Comparative analysis of the Plasmodium falciparum histidine-rich proteins HRP-I, HRP-II and HRP-III in malaria parasites of diverse origin. Parasitology 95:209-227. http://dx.doi.org/10.1017/S0031182000057681.
    • (1987) Parasitology , vol.95 , pp. 209-227
    • Rock, E.P.1    Marsh, K.2    Saul, A.J.3    Wellems, T.E.4    Taylor, D.W.5    Maloy, W.L.6    Howard, R.J.7
  • 44
    • 84867128779 scopus 로고    scopus 로고
    • Opsonization of malaria-infected erythrocytes activities the inflammasome and enhances inflammatory cytokine secretion by human macrophages
    • Zhou J, Ludlow LE, Hasang W, Rogerson SJ, Jaworowski A. 2012. Opsonization of malaria-infected erythrocytes activities the inflammasome and enhances inflammatory cytokine secretion by human macrophages. Malar J 11:343. http://dx.doi.org/10.1186/1475-2875-11-343.
    • (2012) Malar J , vol.11 , pp. 343
    • Zhou, J.1    Ludlow, L.E.2    Hasang, W.3    Rogerson, S.J.4    Jaworowski, A.5
  • 46
    • 27144442743 scopus 로고    scopus 로고
    • High-level cerebellar expression of cytokines and adhesion molecules in fatal, paediatric, cerebral malaria
    • Armah H, Dodoo AK, Wiredu EK, Stiles JK, Adjei AA, Gyasi RK, Tettey Y. 2005. High-level cerebellar expression of cytokines and adhesion molecules in fatal, paediatric, cerebral malaria. Ann Trop Med Parasitol 99: 629-647. http://dx.doi.org/10.1179/136485905X51508.
    • (2005) Ann Trop Med Parasitol , vol.99 , pp. 629-647
    • Armah, H.1    Dodoo, A.K.2    Wiredu, E.K.3    Stiles, J.K.4    Adjei, A.A.5    Gyasi, R.K.6    Tettey, Y.7
  • 49
    • 0035070574 scopus 로고    scopus 로고
    • Central nervous system in cerebral malaria: "innocent bystander" or active participant in the induction of immunopathology?
    • Medana IM, Chaudhri G, Chan-Ling T, Hunt NH. 2001. Central nervous system in cerebral malaria: "innocent bystander" or active participant in the induction of immunopathology? Immunol Cell Biol 79: 101-120. http://dx.doi.org/10.1046/j.1440-1711.2001.00995.x.
    • (2001) Immunol Cell Biol , vol.79 , pp. 101-120
    • Medana, I.M.1    Chaudhri, G.2    Chan-Ling, T.3    Hunt, N.H.4
  • 50
    • 84860903822 scopus 로고    scopus 로고
    • The role of animal models for research on severe malaria
    • Craig AG, Grau GE, Janse C, Kazura JW, Milner D, Barnwell JW, Turner G, Langhorne J; participants of the Hinxton Retreat Meeting on Animal Models for Research on Severe Malaria. 2012. The role of animal models for research on severe malaria. PLoS Pathog 8:e1002401. http://dx.doi.org/10.1371/journal.ppat.1002401.
    • (2012) PLoS Pathog , vol.8
    • Craig, A.G.1    Grau, G.E.2    Janse, C.3    Kazura, J.W.4    Milner, D.5    Barnwell, J.W.6    Turner, G.7    Langhorne, J.8
  • 51
    • 77953616680 scopus 로고    scopus 로고
    • Cerebral malaria: Why experimental murine models are required to understand the pathogenesis of disease
    • De Souza JB, Hafalla JC, Riley EM, Couper KN. 2010. Cerebral malaria: why experimental murine models are required to understand the pathogenesis of disease. Parasitology 137:755-772. http://dx.doi.org/10.1017/S0031182009991715.
    • (2010) Parasitology , vol.137 , pp. 755-772
    • De Souza, J.B.1    Hafalla, J.C.2    Riley, E.M.3    Couper, K.N.4
  • 52
    • 0036213195 scopus 로고    scopus 로고
    • Cerebral malaria: The contribution of studies in animal models to our understanding of immunopathogenesis
    • De Souza JB, Riley EM. 2002. Cerebral malaria: the contribution of studies in animal models to our understanding of immunopathogenesis. Microbes Infect 4:291-300. http://dx.doi.org/10.1016/S1286-4579(02)01541-1.
    • (2002) Microbes Infect , vol.4 , pp. 291-300
    • De Souza, J.B.1    Riley, E.M.2
  • 56
    • 4544382185 scopus 로고    scopus 로고
    • The role of scavenger receptors in pathogen recognition and innate immunity
    • Mukhopadhyay S, Gordon S. 2004. The role of scavenger receptors in pathogen recognition and innate immunity. Immunobiology 209:39-49. http://dx.doi.org/10.1016/j.imbio.2004.02.004.
    • (2004) Immunobiology , vol.209 , pp. 39-49
    • Mukhopadhyay, S.1    Gordon, S.2
  • 58
    • 80052341059 scopus 로고    scopus 로고
    • Caspase-1 activation of interleukin-1beta (IL-1beta) and IL-18 is dispensable for induction of experimental cerebral malaria
    • Kordes M, Matuschewski K, Hafalla JC. 2011. Caspase-1 activation of interleukin-1beta (IL-1beta) and IL-18 is dispensable for induction of experimental cerebral malaria. Infect Immun 79:3633-3641. http://dx.doi.org/10.1128/IAI.05459-11.
    • (2011) Infect Immun , vol.79 , pp. 3633-3641
    • Kordes, M.1    Matuschewski, K.2    Hafalla, J.C.3
  • 59
    • 0026780769 scopus 로고
    • Protection of Aotus monkeys from malaria infection by immunization with recombinant hybrid proteins
    • Knapp B, Hundt E, Enders B, Küpper HA. 1992. Protection of Aotus monkeys from malaria infection by immunization with recombinant hybrid proteins. Infect Immun 60:2397-2401.
    • (1992) Infect Immun , vol.60 , pp. 2397-2401
    • Knapp, B.1    Hundt, E.2    Enders, B.3    Küpper, H.A.4
  • 60
    • 0031964980 scopus 로고    scopus 로고
    • Immunization of Aotus monkeys with recombinant Plasmodium falciparum hybrid proteins does not reproducibly result in protection from malaria infection
    • Kocken CH, Hundt E, Knapp B, Brazel D, Enders B, Narum DL, Wubben JA, Thomas AW. 1998. Immunization of Aotus monkeys with recombinant Plasmodium falciparum hybrid proteins does not reproducibly result in protection from malaria infection. Infect Immun 66: 373-375.
    • (1998) Infect Immun , vol.66 , pp. 373-375
    • Kocken, C.H.1    Hundt, E.2    Knapp, B.3    Brazel, D.4    Enders, B.5    Narum, D.L.6    Wubben, J.A.7    Thomas, A.W.8
  • 61
    • 0024156364 scopus 로고
    • A histidin alanine rich recombinant antigen protects Aotus monkeys from P. falciparum infection
    • Knapp B, Shaw A, Hundt E, Enders B, Küpper HA. 1988. A histidin alanine rich recombinant antigen protects Aotus monkeys from P. falciparum infection. Behring Inst Mitt 1988:349-359.
    • (1988) Behring Inst Mitt , vol.1988 , pp. 349-359
    • Knapp, B.1    Shaw, A.2    Hundt, E.3    Enders, B.4    Küpper, H.A.5
  • 63
    • 34249701886 scopus 로고    scopus 로고
    • Severe malaria in Cameroonian children: Correlation between plasma levels of three soluble inducible adhesion molecules and TNF-alpha
    • Tchinda VH, Tadem AD, Tako EA, Tene G, Fogako J, Nyonglema P, Sama G, Zhou A, Leke RG. 2007. Severe malaria in Cameroonian children: correlation between plasma levels of three soluble inducible adhesion molecules and TNF-alpha. Acta Trop 102:20-28. http://dx.doi.org/10.1016/j.actatropica.2007.02.011.
    • (2007) Acta Trop , vol.102 , pp. 20-28
    • Tchinda, V.H.1    Tadem, A.D.2    Tako, E.A.3    Tene, G.4    Fogako, J.5    Nyonglema, P.6    Sama, G.7    Zhou, A.8    Leke, R.G.9
  • 64
    • 0037102205 scopus 로고    scopus 로고
    • Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria
    • Schofield L, Hewitt MC, Evans K, Siomos MA, Seeberger PH. 2002. Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria. Nature 418:785-789. http://dx.doi.org/10.1038/nature00937.
    • (2002) Nature , vol.418 , pp. 785-789
    • Schofield, L.1    Hewitt, M.C.2    Evans, K.3    Siomos, M.A.4    Seeberger, P.H.5
  • 66
    • 84905004491 scopus 로고    scopus 로고
    • PTEX component HSP101 mediates export of diverse malaria effectors into host erythrocytes
    • Beck JR, Muralidharan V, Oksman A, Goldberg DE. 2014. PTEX component HSP101 mediates export of diverse malaria effectors into host erythrocytes. Nature 511:592-595. http://dx.doi.org/10.1038/nature13574.
    • (2014) Nature , vol.511 , pp. 592-595
    • Beck, J.R.1    Muralidharan, V.2    Oksman, A.3    Goldberg, D.E.4
  • 67
    • 28044457006 scopus 로고    scopus 로고
    • High-efficiency transformation of Plasmodium falciparum by the lepidopteran transposable element piggyBac
    • Balu B, Shoue DA, Fraser MJ, Jr, Adams JH. 2005. High-efficiency transformation of Plasmodium falciparum by the lepidopteran transposable element piggyBac. Proc Natl Acad Sci U S A 102:16391-16396. http://dx.doi.org/10.1073/pnas.0504679102.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 16391-16396
    • Balu, B.1    Shoue, D.A.2    Fraser Jr, M.J.3    Adams, J.H.4
  • 69
    • 27144486896 scopus 로고    scopus 로고
    • Alpha/beta interferon protects against lethal West Nile virus infection by restricting cellular tropism and enhancing neuronal survival
    • Samuel MA, Diamond MS. 2005. Alpha/beta interferon protects against lethal West Nile virus infection by restricting cellular tropism and enhancing neuronal survival. J Virol 79:13350-13361. http://dx.doi.org/10.1128/JVI.79.21.13350-13361.2005.
    • (2005) J Virol , vol.79 , pp. 13350-13361
    • Samuel, M.A.1    Diamond, M.S.2


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