-
1
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
[1] Cong, L., Ran, F.A., Cox, D., Lin, S., Barretto, R., Habib, N., Hsu, P.D., Wu, X., Jiang, W., Marraffini, L.A., Zhang, F., Multiplex genome engineering using CRISPR/Cas systems. Science 339 (2013), 819–823.
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
Habib, N.6
Hsu, P.D.7
Wu, X.8
Jiang, W.9
Marraffini, L.A.10
Zhang, F.11
-
2
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
[2] Mali1, P., Yang, L., Esvelt, K.M., Aach, J., Guell, M., DiCarlo, J.E., Norville, J.E., Church, G.M., RNA-guided human genome engineering via Cas9. Science 339 (2013), 823–826.
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali1, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
DiCarlo, J.E.6
Norville, J.E.7
Church, G.M.8
-
3
-
-
84884165315
-
DNA targeting specificity of RNA-guided Cas9 nucleases
-
[3] Hsu, P.D., Scott, D.A., Weinstein, J.A., Ran, F.A., Konermann, S., Agarwala, V., Li, Y., Fine, E.J., Wu, X., Shalem, O., Cradick, T.J., Marraffini, L.A., Bao, G., Zhang, F., DNA targeting specificity of RNA-guided Cas9 nucleases. Nat. Biotechnol. 31 (2013), 827–832.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 827-832
-
-
Hsu, P.D.1
Scott, D.A.2
Weinstein, J.A.3
Ran, F.A.4
Konermann, S.5
Agarwala, V.6
Li, Y.7
Fine, E.J.8
Wu, X.9
Shalem, O.10
Cradick, T.J.11
Marraffini, L.A.12
Bao, G.13
Zhang, F.14
-
4
-
-
84877103949
-
Generation of gene-modified mice via Cas9/RNA-mediated gene targeting
-
[4] Shen, B., Zhang, J., Wu, H., Wang, J., Ma, K., Li, Z., Zhang, X., Zhang, P., Huang, X., Generation of gene-modified mice via Cas9/RNA-mediated gene targeting. Cell Res. 23 (2013), 720–723.
-
(2013)
Cell Res.
, vol.23
, pp. 720-723
-
-
Shen, B.1
Zhang, J.2
Wu, H.3
Wang, J.4
Ma, K.5
Li, Z.6
Zhang, X.7
Zhang, P.8
Huang, X.9
-
5
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
-
[5] Wang, H., Yang, H., Shivalila, C.S., Dawlaty, M.M., Cheng, A.W., Zhang, F., Jaenisch, R., One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 153 (2013), 910–918.
-
(2013)
Cell
, vol.153
, pp. 910-918
-
-
Wang, H.1
Yang, H.2
Shivalila, C.S.3
Dawlaty, M.M.4
Cheng, A.W.5
Zhang, F.6
Jaenisch, R.7
-
6
-
-
84884289608
-
One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering
-
[6] Yang, H., Wang, H., Shivalila, C.S., Cheng, A.W., Shi, L., Jaenisch, R., One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering. Cell 154 (2013), 1370–1379.
-
(2013)
Cell
, vol.154
, pp. 1370-1379
-
-
Yang, H.1
Wang, H.2
Shivalila, C.S.3
Cheng, A.W.4
Shi, L.5
Jaenisch, R.6
-
7
-
-
84890014631
-
Efficient generation of large-scale genome-modified mice using gRNA and CAS9 endonuclease
-
[7] Fujii, W., Kawasaki, K., Sugiura, K., Naito, K., Efficient generation of large-scale genome-modified mice using gRNA and CAS9 endonuclease. Nucleic Acids Res., 41, 2013, e187.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. e187
-
-
Fujii, W.1
Kawasaki, K.2
Sugiura, K.3
Naito, K.4
-
8
-
-
84897413441
-
Efficient generation of genome-modified mice via offset-nicking by CRISPR/Cas system
-
[8] Fujii, W., Onuma, A., Sugiura, K., Naito, K., Efficient generation of genome-modified mice via offset-nicking by CRISPR/Cas system. Biochem. Biophys. Res. Commun. 445 (2014), 791–794.
-
(2014)
Biochem. Biophys. Res. Commun.
, vol.445
, pp. 791-794
-
-
Fujii, W.1
Onuma, A.2
Sugiura, K.3
Naito, K.4
-
9
-
-
84887104139
-
Orthogonal Cas9 proteins for RNA-guided genome regulation and editing
-
[9] Esvelt, K.M., Mali, P., Braff, J.L., Moosburner, M., Yaung, S.J., Church, G.M., Orthogonal Cas9 proteins for RNA-guided genome regulation and editing. Nat. Methods 10 (2013), 1116–1121.
-
(2013)
Nat. Methods
, vol.10
, pp. 1116-1121
-
-
Esvelt, K.M.1
Mali, P.2
Braff, J.L.3
Moosburner, M.4
Yaung, S.J.5
Church, G.M.6
-
10
-
-
84960467897
-
Streptococcus thermophilus CRISPR-Cas9 systems enable specific editing of the human genome
-
[10] Müller, M., Lee, C.M., Gasiunas, G., Davis, T.H., Cradick, T.J., Siksnys, V., Bao, G., Cathomen, T., Mussolino, C., Streptococcus thermophilus CRISPR-Cas9 systems enable specific editing of the human genome. Mol. Ther. 24 (2016), 636–644.
-
(2016)
Mol. Ther.
, vol.24
, pp. 636-644
-
-
Müller, M.1
Lee, C.M.2
Gasiunas, G.3
Davis, T.H.4
Cradick, T.J.5
Siksnys, V.6
Bao, G.7
Cathomen, T.8
Mussolino, C.9
-
11
-
-
84895832944
-
Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
-
[11] Fonfara, I., Le Rhun, A., Chylinski, K., Makarova, K.S., Lécrivain, A.L., Bzdrenga, J., Koonin, E.V., Charpentier, E., Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems. Nucleic Acids Res. 42 (2014), 2577–2590.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 2577-2590
-
-
Fonfara, I.1
Le Rhun, A.2
Chylinski, K.3
Makarova, K.S.4
Lécrivain, A.L.5
Bzdrenga, J.6
Koonin, E.V.7
Charpentier, E.8
-
12
-
-
58149187865
-
The dynamics and mechanisms of interleukin-1alpha and beta nuclear import
-
[12] Luheshi, N.M., Rothwell, N.J., Brough, D., The dynamics and mechanisms of interleukin-1alpha and beta nuclear import. Traffic 10 (2009), 16–25.
-
(2009)
Traffic
, vol.10
, pp. 16-25
-
-
Luheshi, N.M.1
Rothwell, N.J.2
Brough, D.3
-
13
-
-
84925434302
-
CasFinder: flexible algorithm for identifying specific Cas9 targets in genomes
-
[13] Aach, J., Mali, P., Church, G.M., CasFinder: flexible algorithm for identifying specific Cas9 targets in genomes. bioRxiv, 2014, 005074.
-
(2014)
bioRxiv
, pp. 005074
-
-
Aach, J.1
Mali, P.2
Church, G.M.3
-
14
-
-
84923362368
-
A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate
-
[14] Harel, I., Benayoun, B.A., Machado, B., Singh, P.P., Hu, C.K., Pech, M.F., Valenzano, D.R., Zhang, E., Sharp, S.C., Artandi, S.E., Brunet, A., A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate. Cell 160 (2015), 1013–1026.
-
(2015)
Cell
, vol.160
, pp. 1013-1026
-
-
Harel, I.1
Benayoun, B.A.2
Machado, B.3
Singh, P.P.4
Hu, C.K.5
Pech, M.F.6
Valenzano, D.R.7
Zhang, E.8
Sharp, S.C.9
Artandi, S.E.10
Brunet, A.11
-
15
-
-
84975678715
-
Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system
-
[15] Zetsche, B., Gootenberg, J.S., Abudayyeh, O.O., Slaymaker, I.M., Makarova, K.S., Essletzbichler, P., Volz, S.E., Joung, J., van der Oost, J., Regev, A., Koonin, E.V., Zhang, F., Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system. Cell 163 (2015), 759–771.
-
(2015)
Cell
, vol.163
, pp. 759-771
-
-
Zetsche, B.1
Gootenberg, J.S.2
Abudayyeh, O.O.3
Slaymaker, I.M.4
Makarova, K.S.5
Essletzbichler, P.6
Volz, S.E.7
Joung, J.8
van der Oost, J.9
Regev, A.10
Koonin, E.V.11
Zhang, F.12
-
16
-
-
84937908208
-
Engineered CRISPR-Cas9 nucleases with altered PAM specificities
-
[16] Kleinstiver, B.P., Prew, M.S., Tsai, S.Q., Topkar, V.V., Nguyen, N.T., Zheng, Z., Gonzales, A.P., Li, Z., Peterson, R.T., Yeh, J.J., Aryee, M.J., Joung, J.K., Engineered CRISPR-Cas9 nucleases with altered PAM specificities. Nature 523 (2015), 481–485.
-
(2015)
Nature
, vol.523
, pp. 481-485
-
-
Kleinstiver, B.P.1
Prew, M.S.2
Tsai, S.Q.3
Topkar, V.V.4
Nguyen, N.T.5
Zheng, Z.6
Gonzales, A.P.7
Li, Z.8
Peterson, R.T.9
Yeh, J.J.10
Aryee, M.J.11
Joung, J.K.12
|