Efflux Pump Control Alters Synthetic Gene Circuit Function

ACS Synthetic Biology

Volumn 5, Issue 7, 2016, Pages 619-631

  Diao, Junchen ^a   Charlebois, Daniel A ^b   Nevozhay, Dmitry ^a,c   Bódi, Zoltán ^d   Pál, Csaba ^d   Balázsi, Gábor ^a,b,e  

^a UNIVERSITY OF TEXAS   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c FAR EASTERN FEDERAL UNIVERSITY   (Russian Federation)

^d INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^e St Francis Hospital The Heart Center   (United States)

Author keywords

efflux pump; feedback; stochastic simulation; synthetic gene circuit

Indexed keywords

ABC TRANSPORTER; DOXYCYCLINE; PDR5P PROTEIN; REPRESSOR PROTEIN; SYNTHETIC DNA; UNCLASSIFIED DRUG; GREEN FLUORESCENT PROTEIN; PDR5 PROTEIN, S CEREVISIAE; RECOMBINANT PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; TETRACYCLINE;

ARTICLE; CONTROLLED STUDY; FEEDBACK SYSTEM; FLOW CYTOMETRY; GENE EXPRESSION; GENE FUSION; GENETIC REGULATION; GENETIC TRANSCRIPTION; MATHEMATICAL MODEL; MICHAELIS MENTEN KINETICS; NEGATIVE FEEDBACK; NEGATIVE REGULATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REGULATOR GENE; SACCHAROMYCES CEREVISIAE; SYNTHETIC BIOLOGY; YEAST CELL; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; METABOLISM; THEORETICAL MODEL;

ATP-BINDING CASSETTE TRANSPORTERS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXYCYCLINE; GENE EXPRESSION REGULATION, FUNGAL; GENE REGULATORY NETWORKS; GENES, SYNTHETIC; GREEN FLUORESCENT PROTEINS; MODELS, THEORETICAL; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TETRACYCLINE;

EID: 84978520117     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/acssynbio.5b00154     Document Type: Article

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