Protective Role of Quercetin in Cadmium-Induced Cholinergic Dysfunctions in Rat Brain by Modulating Mitochondrial Integrity and MAP Kinase Signaling

Molecular Neurobiology

Volumn 54, Issue 6, 2017, Pages 4560-4583

  Gupta, Richa ^a,b   Shukla, Rajendra K ^a   Chandravanshi, Lalit P ^a   Srivastava, Pranay ^a   Dhuriya, Yogesh K ^a   Shanker, Jai ^a   Singh, Manjul P ^b   Pant, Aditya B ^a   Khanna, Vinay K ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b UNIVERSITY OF LUCKNOW   (India)

Author keywords

Cadmium; MAP kinase signaling; Neuroprotection; Quercetin; Rat brain

Indexed keywords

ACETYLCHOLINESTERASE; CADMIUM CHLORIDE; CHOLINE ACETYLTRANSFERASE; CHOLINERGIC RECEPTOR; CYTOCHROME C; CYTOCHROME C OXIDASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M4 RECEPTOR; MUSCARINIC RECEPTOR; PROTEIN BAX; PROTEIN BCL 2; QUERCETIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE; CADMIUM; NEUROPROTECTIVE AGENT; PROTEIN KINASE C BETA;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; AUTONOMIC DYSFUNCTION; BRAIN MITOCHONDRION; CHOLINERGIC DYSFUNCTION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVITY; FRONTAL CORTEX; GENE EXPRESSION; HIPPOCAMPUS; LEARNING; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PASSIVE AVOIDANCE; PROTEIN EXPRESSION; RAT; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SPATIAL MEMORY; ANIMAL; AVOIDANCE BEHAVIOR; BRAIN; DRUG EFFECTS; ENZYMOLOGY; GENETICS; MAPK SIGNALING; MAZE TEST; MEMORY; METABOLISM; MITOCHONDRION; PATHOPHYSIOLOGY; ULTRASTRUCTURE; WISTAR RAT;

ACETYLCHOLINESTERASE; ANIMALS; APOPTOSIS; AVOIDANCE LEARNING; BRAIN; CADMIUM; CHOLINE O-ACETYLTRANSFERASE; CYTOCHROMES C; HIPPOCAMPUS; MALE; MAP KINASE SIGNALING SYSTEM; MAZE LEARNING; MEMBRANE POTENTIAL, MITOCHONDRIAL; MEMORY; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; PROTEIN KINASE C BETA; QUERCETIN; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RECEPTORS, MUSCARINIC;

EID: 84978138204     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-016-9950-y     Document Type: Article

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