Hybridization of polyvinylpyrrolidone to a binary composite of curcumin/α-glucosyl stevia improves both oral absorption and photochemical stability of curcumin

Food Chemistry

Volumn 213, Issue , 2016, Pages 668-674

  Kadota, Kazunori ^a   Okamoto, Daiki ^a   Sato, Hideyuki ^b   Onoue, Satomi ^b   Otsu, Shigeyuki ^a   Tozuka, Yuichi ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Curcumin; Oral absorption; Physicochemical stability; Solubility enhancement

Indexed keywords

BIOCHEMISTRY; DRUG PRODUCTS; LOW TEMPERATURE DRYING; SOLUBILITY;

CURCUMIN; EQUILIBRIUM SOLUBILITIES; ORAL ABSORPTION; PHOTOCHEMICAL STABILITY; PHYSICO-CHEMICAL STABILITY; PHYSICOCHEMICAL PROPERTY; POLY VINYL PYRROLIDONE; SOLUBILITY ENHANCEMENT;

SUGAR SUBSTITUTES;

CURCUMIN; POVIDONE; GLUCOSE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG SOLUBILITY; DRUG STABILITY; HYBRIDIZATION; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PARTICLE SIZE; PHOTOCHEMISTRY; PHOTODEGRADATION; PHYSICAL CHEMISTRY; RAT; SCANNING ELECTRON MICROSCOPY; X RAY POWDER DIFFRACTION; ANIMAL; BIOAVAILABILITY; CHEMISTRY; DRUG EFFECTS; GASTROINTESTINAL ABSORPTION; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; SOLUBILITY; SPRAGUE DAWLEY RAT; STEVIA; X RAY DIFFRACTION;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CURCUMIN; GASTROINTESTINAL ABSORPTION; GLUCOSE; MALE; PHOTOCHEMICAL PROCESSES; POVIDONE; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; STEVIA; X-RAY DIFFRACTION;

EID: 84978127965     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2016.07.025     Document Type: Article

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