Solid-state characterization and dissolution properties of meloxicam-moringa coagulant-PVP ternary solid dispersions

AAPS PharmSciTech

Volumn 14, Issue 2, 2013, Pages 569-577

  Noolkar, Suhail B ^a   Jadhav, Namdeo R ^a   Bhende, Santosh A ^a   Killedar, Suresh G ^a  

^a BHARATI VIDYAPEETH COLLEGE OF PHARMACY   (India)

Author keywords

amorphization; moringa coagulant; solubility enhancement; synergism; ternary solid dispersions

Indexed keywords

MELOXICAM; MORINGA COAGULANT; POLYMER; POVIDONE; UNCLASSIFIED DRUG;

ARTICLE; BULK DENSITY; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG SOLUBILITY; DRUG STABILITY; DRUG STORAGE; DRUG SYNTHESIS; IN VITRO STUDY; INFRARED SPECTROSCOPY; PRIORITY JOURNAL; SOLID DISPERSION; SOLID STATE; X RAY DIFFRACTION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTICOAGULANTS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; COMPRESSIVE STRENGTH; DRUG COMBINATIONS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KINETICS; MORINGA; PLANT PROTEINS; POVIDONE; SEEDS; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TABLETS; TECHNOLOGY, PHARMACEUTICAL; THIAZINES; THIAZOLES; X-RAY DIFFRACTION;

EID: 84879125765     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-013-9941-5     Document Type: Article

References (30)

1. Yu LX et al. A biopharmaceutics classification system: the scientific basis for bio waiver extensions. Pharm Res. 2002;19:921-5.
2. Chowdary KPR, Hymavathi R. Enhancement of dissolution rate of meloxicam. Indian J Pharm Sci. 2001;63(2):150-4.
3. Patidar K, Soni M, Sharma DK, Jain SK. Solid dispersion: approaches, technology involved, unmet need & challenges. Drug Invent Today. 2010;2(7):349-57.
4. Wade A, Weller PJ, editors. Handbook of pharmaceutical excipients. Washington: American Pharmaceutical Association/The Pharmaceutical Press; 1994. p. 220-399.
5. Arakawa T, Kita Y, Koyamac HA. Solubility enhancement of gluten and organic compounds by arginine. Int J Pharm. 2008;355:220-3.
6. Bhende S, Jadhav N. Moringa coagulant as a stabilizer for amorphous solids: part I. AAPS PharmSciTech. 2012;13:400-10.
7. Kwaambwa HM, Maikokera R. A fluorescence spectroscopic study of a coagulating protein extracted from Moringa oleifera seeds. Colloids Surf B. 2007;60:213-20.
8. Gassenschmidt U, Jany KD, Tauscher B, Niebergall H. Isolation and characterization of a flocculating protein from Moringa oleifera Lam. Biochim Biophys Acta. 1995;1243:477-81.
9. Mura P, Bettinettib GP, Cirria M, Maestrellia F, Sorrentib M, Catenaccib L. Solid-state characterization and dissolution properties of naproxen-arginine-hydroxypropyl-β-cyclodextrin ternary system. Eur J Pharm Biopharm. 2005;59:99-106.
10. Mura P, Maestrellia F, Cirri M. Ternary systems of naproxen with hydroxypropyl-β-cyclodextrin and amino acids. Int J Pharm. 2003;260:293-302.
11. El-Maradny HA, Mortada SA, Kamel OA, Hikal AH. Characterization of ternary complexes of meloxicam-HPβCD and PVP or l-arginine prepared by the spray-drying technique. Acta Pharma. 2008;58:455-66.
12. Xiaodan Q, Jing Z, Wei W, Deying C. Solubility and stability of indomethacin in arginine-assisted solubilization system. Pharm Dev Technol. 2011;13:1-4.
13. Bramhane D, Saindane N, Vavia P. Inclusion complexation of weakly acidic NSAID with β-cyclodextrin: selection of arginine, an amino acid, as a novel ternary component. J Incl Phenom Macrocycl Chem. 2011;69:453-60.
14. Hirasawa N, Ishise S, Miyata H, Danjo K. Physicochemical characterization and drug release studies of nilvadipine solid dispersions using water-insoluble polymer as a carrier. Drug Dev Ind Pharm. 2003;29(3):339-44.
15. Hirasawa N, Ishise S, Miyata H, Danjo K. Application of nilvadipine solid dispersion to tablet formulation and manufacturing using crospovidone and methylcellulose as dispersion carriers. Chem Pharm Bull. 2004;52:244-7.
16. Takada K, Oh-hashi M, Furuya Y, Yoshikawa H, Muranishi S. Enteric solid dispersion of ciclosporin A (CiA) having potential to deliver CiA into lymphatics. Chem Pharm Bull. 1989;37(2):471-4.
17. Horisawa E, Danjo K, Haruna M. Physical properties of solid dispersion of a nonsteroidal anti-inflammatory drug (M-5011) with Eudragit E. Drug Dev Ind Pharm. 2000;26:1271-8.
18. Jung JY, Yoo SD, Lee SH, Kim KH, Yoon DS, Lee KH. Enhanced solubility and dissolution rate of itraconazole by a solid dispersion technique. Int J Pharm. 1999;187:209-18.
19. Sharma D, Soni M, Kumar S, Gupta GD. Solubility enhancement - eminent role in poorly soluble drugs. Res J Pharm Tech. 2009;2(2):222.
20. Chiou WL, Riegelman S. Pharmaceutical applications of solid dispersion systems. J Pharm Sci. 1971;60:1281-302.
21. Reintjes T. Solubility enhancement with BASF Pharma polymers. Solubilizer compendium. 2011;7-128. BASF chemical company. http://www.pharma-ingredients. basf.com.
22. Ndabigengesere A, Narasiah KS. Quality of water treated by coagulation using Moringa oleifera seeds. Water Res. 1998;32(3):781-91.
23. Ndabigengesere A, Narasiah KS, Talbot BG. Active agents and mechanism of coagulation of turbid waters using Moringa oleifera. Water Res. 1995;29(2):703-10.
24. Train D. Some aspects of the property of angle of repose of powders. J Pharm Pharmacol. 1958;10:127T-34T.
25. Carr RL. Evaluating flow properties of solids. Chem Eng. 1965;72:163-8.
26. Kawakita K., Ludde K. H. Some considerations on powder compression equations. Powder Technol. 1970-1971;4:61-8.
27. Heckel RW. Density pressure relationship in powder compaction. Trans Metall Soc AIME. 1961;221:671-5.
28. Fell JT, Newton JM. Determination of tablet strength by the diametral compression test. J Pharm Sci. 1970;59:688-91.
29. Leuenberger H. The compressibility and compactibility of powder systems. Int J Pharm. 1982;12:41-55.
30. Okuda T, Baes AU, Nishijima W, Okada M. Improvement of extraction method of coagulation active components from Moringa oleifera seed. Water Res. 1999;33(15):3373-8.