Highly sensitive and unbiased approach for elucidating antibody repertoires

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 28, 2016, Pages 7846-7851

  Lin, Sherry G ^a,b   Ba, Zhaoqing ^a,b   Du, Zhou ^b,c   Zhang, Yu ^a,b   Hu, Jiazhi ^a,b   Alt, Frederick W ^a,b,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Antibody repertoires; HTGTS Rep seq; V(D)J recombination

Indexed keywords

ANTIBODY; B LYMPHOCYTE RECEPTOR; GENOMIC DNA; IMMUNOGLOBULIN M; LEUKOSIALIN;

ANIMAL EXPERIMENT; ANTIBODY AFFINITY; ANTIGEN BINDING; ARTICLE; CELL MATURATION; CLINICAL EVALUATION; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; EXON; GENE MUTATION; GENE REARRANGEMENT; GENETIC IDENTIFICATION; HIGH THROUGHPUT SEQUENCING; HUMAN; LINEAR AMPLIFICATION MEDIATED HIGH THROUGHPUT GENOME WIDE TRANSLOCATION SEQUENCING; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SEQUENCE ANALYSIS; VDJ RECOMBINATION; ANIMAL; EVALUATION STUDY; GENETIC PROCEDURES; MOUSE;

ANIMALS; ANTIBODIES; GENETIC TECHNIQUES; MICE; V(D)J RECOMBINATION;

EID: 84978127798     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1608649113     Document Type: Article

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