Radiofrequency renal denervation protects the ischemic heart via inhibition of GRK2 and increased nitric oxide signaling

Circulation Research

Volumn 119, Issue 3, 2016, Pages 470-480

  Polhemus, David J ^a   Gao, Juan ^a   Scarborough, Amy L ^a   Trivedi, Rishi ^a   McDonough, Kathleen H ^a   Goodchild, Traci T ^a   Smart, Frank ^a   Kapusta, Daniel R ^a   Lefer, David J ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

G protein coupled receptor kinases; nervous system; nitric oxide; oxidative stress; radiofrequency; renal denervation; sympathetic

Indexed keywords

ANTIOXIDANT; COPPER ZINC SUPEROXIDE DISMUTASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; G PROTEIN COUPLED RECEPTOR KINASE 2; GLUTATHIONE PEROXIDASE 1; NITRIC OXIDE; ADRBK1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY OCCLUSION; ENZYME INHIBITION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE ISCHEMIA; KIDNEY DENERVATION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RADIOFREQUENCY; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CATHETER ABLATION; DENERVATION; INNERVATION; KIDNEY; METABOLISM; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; PHYSIOLOGY; PROCEDURES; SURGERY; WISTAR KYOTO RAT;

ANIMALS; CATHETER ABLATION; DENERVATION; G-PROTEIN-COUPLED RECEPTOR KINASE 2; KIDNEY; MALE; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; NITRIC OXIDE; OXIDATIVE STRESS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SIGNAL TRANSDUCTION;

EID: 84978055839     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.115.308278     Document Type: Article

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