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Volumn 17, Issue 7, 2016, Pages

TSPO PIGA Ligands Promote Neurosteroidogenesis and Human Astrocyte Well-Being

Author keywords

Astrocytes; Cellular proliferation; Neurosteroidogenesis; Oxidative metabolism; PIGA ligands; Translocator protein

Indexed keywords

7 CHLORO 2 (3 PYRIDYL) ALPHA TETRALONE; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; N,N DIALKYL 2 PHENYLINDOL 3 YLGLYOXYLAMIDE; NEUROSTEROID; PREGNENOLONE; TRANSLOCATOR PROTEIN 18 KDA; TRILOSTANE; UNCLASSIFIED DRUG; INDOLE DERIVATIVE; N,N-DI-N-BUTYL-5-CHLORO-2-(4-CHLOROPHENYL)INDOL-3-YLGLYOXYLAMIDE;

EID: 84976591482     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms17071028     Document Type: Article
Times cited : (35)

References (87)
  • 1
    • 0033198566 scopus 로고    scopus 로고
    • Neuroactive steroids: Mechanisms of action and neuropsychopharmacological perspectives
    • [CrossRef]
    • Rupprecht, R.; Holsboer, F. Neuroactive steroids: Mechanisms of action and neuropsychopharmacological perspectives. Trends Neurosci. 1999, 9, 410–416. [CrossRef]
    • (1999) Trends Neurosci , vol.9 , pp. 410-416
    • Rupprecht, R.1    Holsboer, F.2
  • 2
    • 78649361562 scopus 로고    scopus 로고
    • Neurosteroids: Endogenous role in the human brain and therapeutic potentials
    • [PubMed]
    • Reddy, D.S. Neurosteroids: Endogenous role in the human brain and therapeutic potentials. Prog. Brain Res. 2010, 186, 113–137. [PubMed]
    • (2010) Prog. Brain Res , vol.186 , pp. 113-137
    • Reddy, D.S.1
  • 3
    • 0017192085 scopus 로고
    • Autoradiographic localization of hormone-concentrating cells in the brain of the female rhesus monkey
    • [CrossRef][PubMed]
    • Pfaff, D.W.; Gerlach, J.L.; McEwen, B.S.; Ferin, M.; Carmel, P.; Zimmerman, E.A. Autoradiographic localization of hormone-concentrating cells in the brain of the female rhesus monkey. J. Comp. Neurol. 1976, 170, 279–293. [CrossRef][PubMed]
    • (1976) J. Comp. Neurol , vol.170 , pp. 279-293
    • Pfaff, D.W.1    Gerlach, J.L.2    McEwen, B.S.3    Ferin, M.4    Carmel, P.5    Zimmerman, E.A.6
  • 4
    • 0000693795 scopus 로고    scopus 로고
    • Steroid modulation of the nicotinic acetylcholine receptor
    • 1999th ed.; Baulieu, E.E., Robel, P., Schumacher,M., Eds.; Humana Press: Totowa, NJ, USA
    • Buisson, B.; Bertrand, D. Steroid modulation of the nicotinic acetylcholine receptor. In Neurosteroids: A New Regulatory Function in the Nervous System, 1999th ed.; Baulieu, E.E., Robel, P., Schumacher,M., Eds.; Humana Press: Totowa, NJ, USA, 1999.
    • (1999) Neurosteroids: A New Regulatory Function in the Nervous System
    • Buisson, B.1    Bertrand, D.2
  • 5
    • 0000158068 scopus 로고    scopus 로고
    • Modulation of ionotropic glutamate receptors by neuroactive steroids
    • 1999th ed.; Baulieu, E.E., Robel, P., Schumacher, M., Eds.; Humana Press: Totowa, NJ, USA
    • Gibbs, T.T.; Yaghoubi, N.; Weaver, C.E., Jr.; Park-Chung, M.; Russek, S.J.; Farb, D.H. Modulation of ionotropic glutamate receptors by neuroactive steroids. In Neurosteroids: A New Regulatory Function in the Nervous System, 1999th ed.; Baulieu, E.E., Robel, P., Schumacher, M., Eds.; Humana Press: Totowa, NJ, USA, 1999; pp. 167–190.
    • (1999) Neurosteroids: A New Regulatory Function in the Nervous System , pp. 167-190
    • Gibbs, T.T.1    Yaghoubi, N.2    Weaver, C.E.3    Park-Chung, M.4    Russek, S.J.5    Farb, D.H.6
  • 6
    • 0000490279 scopus 로고    scopus 로고
    • Neurosteroid antagonists of the GABAA receptors
    • 1999th ed.; Baulieu, E.E., Robel, P., Schumacher, M., Eds.; Humana Press: Totowa, NJ, USA
    • Majewska, M.D. Neurosteroid antagonists of the GABAA receptors. In Neurosteroids: A New Regulatory Function in the Nervous System, 1999th ed.; Baulieu, E.E., Robel, P., Schumacher, M., Eds.; Humana Press: Totowa, NJ, USA, 1999; pp. 155–166.
    • (1999) Neurosteroids: A New Regulatory Function in the Nervous System , pp. 155-166
    • Majewska, M.D.1
  • 7
    • 0033586349 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage
    • [CrossRef]
    • Bastianetto, S.; Ramassamy, C.; Poirier, J.; Quirion, R. Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage. Mol. Brain Res. 1999, 6, 35–41. [CrossRef]
    • (1999) Mol. Brain Res , vol.6 , pp. 35-41
    • Bastianetto, S.1    Ramassamy, C.2    Poirier, J.3    Quirion, R.4
  • 8
    • 0028801074 scopus 로고
    • Putative receptor for neurosteroids on the GABAA receptor complex: The pharmacological properties and therapeutic potential of epalons
    • [PubMed]
    • Gee, K.W.; McCaule, L.D.; Lan, N.C. A putative receptor for neurosteroids on the GABAA receptor complex: The pharmacological properties and therapeutic potential of epalons. Crit. Rev. Neurobiol. 1995, 9, 207–227. [PubMed]
    • (1995) Crit. Rev. Neurobiol , vol.9 , pp. 207-227
    • Gee, K.W.1    McCaule, L.D.2    Lan, N.3
  • 10
    • 33646862809 scopus 로고    scopus 로고
    • Fast nongenomic effects of steroids on synaptic transmission and role of endogenous neurosteroids in spinal pain pathways
    • [CrossRef]
    • Schlichter, R.; Keller, A.F.; de Roo, M.; Breton, J.D.; Inquimbert, P.; Poisbeau, P. Fast nongenomic effects of steroids on synaptic transmission and role of endogenous neurosteroids in spinal pain pathways. J. Mol. Neurosci. 2006, 28, 33–51. [CrossRef]
    • (2006) J. Mol. Neurosci , vol.28 , pp. 33-51
    • Schlichter, R.1    Keller, A.F.2    De Roo, M.3    Breton, J.D.4    Inquimbert, P.5    Poisbeau, P.6
  • 11
    • 34548583303 scopus 로고    scopus 로고
    • Neurosteroid modulation of synaptic and extrasynaptic GABA(A) receptors
    • [CrossRef][PubMed]
    • Herd, M.B.; Belelli, D.; Lambert, J.J. Neurosteroid modulation of synaptic and extrasynaptic GABA(A) receptors. Pharmacol. Ther. 2007, 116, 20–34. [CrossRef][PubMed]
    • (2007) Pharmacol. Ther , vol.116 , pp. 20-34
    • Herd, M.B.1    Belelli, D.2    Lambert, J.J.3
  • 12
    • 33947637046 scopus 로고    scopus 로고
    • GABA and neuroactive steroid interactions in glia: New roles for old players?
    • [CrossRef][PubMed]
    • Magnaghi, V. GABA and neuroactive steroid interactions in glia: New roles for old players? Curr. Neuropharmacol. 2007, 5, 47–64. [CrossRef][PubMed]
    • (2007) Curr. Neuropharmacol , vol.5 , pp. 47-64
    • Magnaghi, V.1
  • 13
    • 0028343330 scopus 로고
    • Gonadal hormone regulation of insulin-like growth factor-I-like immunoreactivity in hypothalamic astroglia of developing and adult rats
    • [CrossRef][PubMed]
    • Duenas, M.; Luquin, S.; Chowen, J.A.; Torres-Aleman, I.; Naftolin, F.; Garcia-Segura, L.M. Gonadal hormone regulation of insulin-like growth factor-I-like immunoreactivity in hypothalamic astroglia of developing and adult rats. Neuroendocrinology 1994, 59, 528–538. [CrossRef][PubMed]
    • (1994) Neuroendocrinology , vol.59 , pp. 528-538
    • Duenas, M.1    Luquin, S.2    Chowen, J.A.3    Torres-Aleman, I.4    Naftolin, F.5    Garcia-Segura, L.M.6
  • 14
    • 0029039471 scopus 로고
    • Basic fibroblast growth factor protects against excitotoxicity and chemical hypoxia in both neonatal and adult rats
    • [CrossRef][PubMed]
    • Kirschner, P.B.; Henshaw, R.; Weise, J.; Trubetskoy, V.; Finklestein, S.; Schulz, J.B.; Beal, M.F. Basic fibroblast growth factor protects against excitotoxicity and chemical hypoxia in both neonatal and adult rats. J. Cereb. Blood Flow Metab. 1995, 15, 619–623. [CrossRef][PubMed]
    • (1995) J. Cereb. Blood Flow Metab , vol.15 , pp. 619-623
    • Kirschner, P.B.1    Henshaw, R.2    Weise, J.3    Trubetskoy, V.4    Finklestein, S.5    Schulz, J.B.6    Beal, M.F.7
  • 15
    • 0031079601 scopus 로고    scopus 로고
    • Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro
    • [CrossRef][PubMed]
    • Stone, D.J.; Rozovsky, I.; Morgan, T.E.; Anderson, C.P.; Hajian, H.; Finch, C.E. Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro. Exp. Neurol. 1997, 143, 313–318. [CrossRef][PubMed]
    • (1997) Exp. Neurol , vol.143 , pp. 313-318
    • Stone, D.J.1    Rozovsky, I.2    Morgan, T.E.3    Anderson, C.P.4    Hajian, H.5    Finch, C.E.6
  • 16
    • 0033216112 scopus 로고    scopus 로고
    • Ovariectomy of adult rats leads to increased expression of astrocytic basic fibroblast growth factor in the ventral tegmental area and in dopaminergic projection regions of the entorhinal and prefrontal cortex
    • [PubMed]
    • Flores, C.; Salmaso, N.; Cain, S.; Rodaros, D.; Stewart, J. Ovariectomy of adult rats leads to increased expression of astrocytic basic fibroblast growth factor in the ventral tegmental area and in dopaminergic projection regions of the entorhinal and prefrontal cortex. J. Neurosci. 1999, 19, 8665–8673. [PubMed]
    • (1999) J. Neurosci , vol.19 , pp. 8665-8673
    • Flores, C.1    Salmaso, N.2    Cain, S.3    Rodaros, D.4    Stewart, J.5
  • 17
    • 0034127135 scopus 로고    scopus 로고
    • Estrogen-astrocyte-luteinizing hormone-releasing hormone signaling: A role for transforming growth factor-˜1
    • [CrossRef][PubMed]
    • Buchanan, C.D.; Mahesh, V.B.; Brann, D.W. Estrogen-astrocyte-luteinizing hormone-releasing hormone signaling: A role for transforming growth factor- ˜1. Biol. Reprod. 2000, 62, 1710–1721. [CrossRef][PubMed]
    • (2000) Biol. Reprod , vol.62 , pp. 1710-1721
    • Buchanan, C.D.1    Mahesh, V.B.2    Brann, D.W.3
  • 18
    • 0036798756 scopus 로고    scopus 로고
    • Oestrogens, via transforming growth factor —, modulate basic fibroblast growth factor synthesis in hypothalamic astrocytes: In vitro observations
    • [CrossRef][PubMed]
    • Galbiati, M.; Martini, L.; Melcangi, R.C. Oestrogens, via transforming growth factor —, modulate basic fibroblast growth factor synthesis in hypothalamic astrocytes: In vitro observations. J. Neuroendocrinol. 2002, 14, 829–835. [CrossRef][PubMed]
    • (2002) J. Neuroendocrinol , vol.14 , pp. 829-835
    • Galbiati, M.1    Martini, L.2    Melcangi, R.C.3
  • 19
    • 1542722935 scopus 로고    scopus 로고
    • Alterations in IGF-I, BDNF and NT-3 levels following experimental brain trauma and the effect of IGF-I administration
    • [CrossRef][PubMed]
    • Kazanis, I.; Giannakopoulou, M.; Philippidis, H.; Stylianopoulou, F. Alterations in IGF-I, BDNF and NT-3 levels following experimental brain trauma and the effect of IGF-I administration. Exp. Neurol. 2004, 186, 221–234. [CrossRef][PubMed]
    • (2004) Exp. Neurol , vol.186 , pp. 221-234
    • Kazanis, I.1    Giannakopoulou, M.2    Philippidis, H.3    Stylianopoulou, F.4
  • 20
    • 26944486635 scopus 로고    scopus 로고
    • 17˜-estradiol rescues spinal motoneurons from AMPA-induced toxicity: A role for glial cells
    • [CrossRef][PubMed]
    • Platania, P.; Seminara, G.; Aronica, E.; Troost, D.; Vincenza Catania, M.; Angela Sortino, M. 17˜-estradiol rescues spinal motoneurons from AMPA-induced toxicity: A role for glial cells. Neurobiol. Dis. 2005, 20, 461–470. [CrossRef][PubMed]
    • (2005) Neurobiol. Dis , vol.20 , pp. 461-470
    • Platania, P.1    Seminara, G.2    Aronica, E.3    Troost, D.4    Vincenza Catania, M.5    Angela Sortino, M.6
  • 21
    • 33644807832 scopus 로고    scopus 로고
    • Interactions of insulin-like growth factor-I and estrogen in the brain
    • [PubMed]
    • Mendez, P.; Cardona-Gomez, G.P.; Garcia-Segura, L.M. Interactions of insulin-like growth factor-I and estrogen in the brain. Adv. Exp. Med. Biol. 2005, 567, 285–303. [PubMed]
    • (2005) Adv. Exp. Med. Biol , vol.567 , pp. 285-303
    • Mendez, P.1    Cardona-Gomez, G.P.2    Garcia-Segura, L.M.3
  • 22
    • 33845590845 scopus 로고    scopus 로고
    • Role of astrocytes in estrogen-mediated neuroprotection
    • [CrossRef][PubMed]
    • Dhandapani, K.M.; Brann, D.W. Role of astrocytes in estrogen-mediated neuroprotection. Exp. Gerontol. 2007, 42, 70–75. [CrossRef][PubMed]
    • (2007) Exp. Gerontol , vol.42 , pp. 70-75
    • Dhandapani, K.M.1    Brann, D.W.2
  • 23
    • 73349128704 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators decrease the production of interleukin-6 and interferon-gamma-inducible protein-10 by astrocytes exposed to inflammatory challenge in vitro
    • [CrossRef][PubMed]
    • Cerciat, M.; Unkila, M.; Garcia-Segura, L.M.; Arevalo, M.A. Selective estrogen receptor modulators decrease the production of interleukin-6 and interferon-gamma-inducible protein-10 by astrocytes exposed to inflammatory challenge in vitro. Glia 2010, 58, 93–102. [CrossRef][PubMed]
    • (2010) Glia , vol.58 , pp. 93-102
    • Cerciat, M.1    Unkila, M.2    Garcia-Segura, L.M.3    Arevalo, M.A.4
  • 24
    • 84880202236 scopus 로고    scopus 로고
    • Flavonoids induce the synthesis and secretion of neurotrophic factors in cultured rat astrocytes: A signaling response mediated by estrogen receptor
    • [CrossRef][PubMed]
    • Xu, S.L.; Bi, C.W.; Choi, R.C.; Zhu, K.Y.; Miernisha, A.; Dong, T.T.; Tsim, K.W. Flavonoids induce the synthesis and secretion of neurotrophic factors in cultured rat astrocytes: A signaling response mediated by estrogen receptor. Evid. Based Complement. Altern. Med. 2013, 2013. [CrossRef][PubMed]
    • (2013) Evid. Based Complement. Altern. Med
    • Xu, S.L.1    Bi, C.W.2    Choi, R.C.3    Zhu, K.Y.4    Miernisha, A.5    Dong, T.T.6    Tsim, K.W.7
  • 25
    • 84879315379 scopus 로고    scopus 로고
    • Estrogen mediates neuroprotection and anti-inflammatory effects during EAE through ER˜ signaling on astrocytes but not through ER˜ signaling on astrocytes or neurons
    • [CrossRef][PubMed]
    • Spence, R.D.; Wisdom, A.J.; Cao, Y.; Hill, H.M.; Mongerson, C.R.; Stapornkul, B.; Itoh, N.; Sofroniew, M.V.; Voskuhl, R.R. Estrogen mediates neuroprotection and anti-inflammatory effects during EAE through ER˜ signaling on astrocytes but not through ER˜ signaling on astrocytes or neurons. J. Neurosci. 2013, 33, 10924–10933. [CrossRef][PubMed]
    • (2013) J. Neurosci , vol.33 , pp. 10924-10933
    • Spence, R.D.1    Wisdom, A.J.2    Cao, Y.3    Hill, H.M.4    Mongerson, C.R.5    Stapornkul, B.6    Itoh, N.7    Sofroniew, M.V.8    Voskuhl, R.R.9
  • 26
    • 84864573426 scopus 로고    scopus 로고
    • GPR30 regulates glutamate transporter GLT-1 expression in rat primary astrocytes
    • [CrossRef][PubMed]
    • Lee, E.; Sidoryk-Wêgrzynowicz, M.; Wang, N.; Webb, A.; Son, D.S.; Lee, K.; Aschner, M. GPR30 regulates glutamate transporter GLT-1 expression in rat primary astrocytes. J. Biol. Chem. 2012, 287, 26817–26828. [CrossRef][PubMed]
    • (2012) J. Biol. Chem , vol.287 , pp. 26817-26828
    • Lee, E.1    Sidoryk-Wêgrzynowicz, M.2    Wang, N.3    Webb, A.4    Son, D.S.5    Lee, K.6    Aschner, M.7
  • 27
    • 45549091568 scopus 로고    scopus 로고
    • Oestrogen influences on mitochondrial gene expression and respiratory chain activity in cortical and mesencephalic astrocytes
    • Araújo, G.W.; Beyer, C.; Arnold, S. Oestrogen influences on mitochondrial gene expression and respiratory chain activity in cortical and mesencephalic astrocytes. J. Neuroendocrinol. 2008, 20, 930–941.
    • (2008) J. Neuroendocrinol , vol.20 , pp. 930-941
    • Araújo, G.W.1    Beyer, C.2    Arnold, S.3
  • 28
    • 44249087833 scopus 로고    scopus 로고
    • Progesterone and estrogen regulate oxidative metabolism in brain mitochondria
    • [CrossRef][PubMed]
    • Irwin, R.W.; Yao, J.; Hamilton, R.T.; Cadenas, E.; Brinton, R.D.; Nilsen, J. Progesterone and estrogen regulate oxidative metabolism in brain mitochondria. Endocrinology 2008, 149, 3167–3175. [CrossRef][PubMed]
    • (2008) Endocrinology , vol.149 , pp. 3167-3175
    • Irwin, R.W.1    Yao, J.2    Hamilton, R.T.3    Cadenas, E.4    Brinton, R.D.5    Nilsen, J.6
  • 29
    • 84891379545 scopus 로고    scopus 로고
    • Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis
    • [CrossRef][PubMed]
    • Morohaku, K.; Pelton, S.H.; Daugherty, D.J.; Butler, W.R.; Deng, W.; Selvaraj, V. Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis. Endocrinology 2014, 155, 89–97. [CrossRef][PubMed]
    • (2014) Endocrinology , vol.155 , pp. 89-97
    • Morohaku, K.1    Pelton, S.H.2    Daugherty, D.J.3    Butler, W.R.4    Deng, W.5    Selvaraj, V.6
  • 30
    • 84907293074 scopus 로고    scopus 로고
    • Peripheral benzodiazepine receptor/translocator protein global knock-out mice are viable with no effects on steroid hormone biosynthesis
    • [CrossRef][PubMed]
    • Tu, L.N.; Morohaku, K.; Manna, P.R.; Pelton, S.H.; Butler, W.R.; Stocco, D.M.; Selvaraj, V. Peripheral benzodiazepine receptor/translocator protein global knock-out mice are viable with no effects on steroid hormone biosynthesis. J. Biol. Chem. 2014, 289, 27444–27454. [CrossRef][PubMed]
    • (2014) J. Biol. Chem , vol.289 , pp. 27444-27454
    • Tu, L.N.1    Morohaku, K.2    Manna, P.R.3    Pelton, S.H.4    Butler, W.R.5    Stocco, D.M.6    Selvaraj, V.7
  • 32
    • 68749119440 scopus 로고    scopus 로고
    • Translocator protein (18 kDa) TSPO: An emerging therapeutic target in neurotrauma. Exp
    • [CrossRef][PubMed]
    • Papadopoulos, V.; Lecanu, L. Translocator protein (18 kDa) TSPO: An emerging therapeutic target in neurotrauma. Exp. Neurol. 2009, 219, 53–57. [CrossRef][PubMed]
    • (2009) Neurol , vol.219 , pp. 53-57
    • Papadopoulos, V.1    Lecanu, L.2
  • 33
    • 71249129127 scopus 로고    scopus 로고
    • Neurosteroids’ effects and mechanisms for social, cognitive, emotional, and physical functions
    • [CrossRef][PubMed]
    • Frye, C.A. Neurosteroids’ effects and mechanisms for social, cognitive, emotional, and physical functions. Psychoneuroendocrinology 2009, 34, S143–S161. [CrossRef][PubMed]
    • (2009) Psychoneuroendocrinology , vol.34 , pp. S143-S161
    • Frye, C.A.1
  • 34
    • 84931274608 scopus 로고    scopus 로고
    • Conditional steroidogenic cell-targeted deletion of TSPO Unveils a Crucial role in Viability and Hormone-Dependent Steroid Formation
    • [CrossRef][PubMed]
    • Fan, J.; Campioli, E.; Midzak, A.; Culty, M.; Papadopoulos, V. Conditional steroidogenic cell-targeted deletion of TSPO Unveils a Crucial role in Viability and Hormone-Dependent Steroid Formation. Proc. Natl. Acad. Sci. USA 2015, 112, 7261–7266. [CrossRef][PubMed]
    • (2015) Proc. Natl. Acad. Sci. USA , vol.112 , pp. 7261-7266
    • Fan, J.1    Campioli, E.2    Midzak, A.3    Culty, M.4    Papadopoulos, V.5
  • 35
    • 0027381252 scopus 로고
    • Neurosteroid biosynthesis: Genes for adrenal steroidogenic enzymes are expressed in the brain
    • [CrossRef]
    • Mellon, S.H.; Deschepper, C.F. Neurosteroid biosynthesis: Genes for adrenal steroidogenic enzymes are expressed in the brain. Brain Res. 1993, 629, 283–292. [CrossRef]
    • (1993) Brain Res , vol.629 , pp. 283-292
    • Mellon, S.H.1    Deschepper, C.F.2
  • 36
    • 4644308387 scopus 로고    scopus 로고
    • The steroidogenic acute regulatory protein is expressed in steroidogenic cells of the day-old brain
    • [CrossRef][PubMed]
    • King, S.R.; Ginsberg, S.D.; Ishii, T.; Smith, R.G.; Parker, K.L.; Lamb, D.J. The steroidogenic acute regulatory protein is expressed in steroidogenic cells of the day-old brain. Endocrinology 2004, 145, 4775–4780. [CrossRef][PubMed]
    • (2004) Endocrinology , vol.145 , pp. 4775-4780
    • King, S.R.1    Ginsberg, S.D.2    Ishii, T.3    Smith, R.G.4    Parker, K.L.5    Lamb, D.J.6
  • 38
    • 0042737939 scopus 로고    scopus 로고
    • Peripheral-type benzodiazepine receptor: Structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis
    • [CrossRef]
    • Lacapère, J.J.; Papadopoulos, V. Peripheral-type benzodiazepine receptor: Structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis. Steroids 2003, 68, 569–585. [CrossRef]
    • (2003) Steroids , vol.68 , pp. 569-585
    • Lacapère, J.J.1    Papadopoulos, V.2
  • 39
    • 84860273370 scopus 로고    scopus 로고
    • Translocator protein (TSPO) and neurosteroids: Implications in psychiatric disorders
    • [CrossRef][PubMed]
    • Da Pozzo, E.; Costa, B.; Martini, C. Translocator protein (TSPO) and neurosteroids: Implications in psychiatric disorders. Curr. Mol. Med. 2012, 12, 426–442. [CrossRef][PubMed]
    • (2012) Curr. Mol. Med , vol.12 , pp. 426-442
    • Da Pozzo, E.1    Costa, B.2    Martini, C.3
  • 41
    • 17744386969 scopus 로고    scopus 로고
    • Ro5-4864, a peripheral benzodiazepine receptor ligand, reduces reactive gliosis and protects hippocampal hilar neurons from kainic acid excitotoxicity
    • [CrossRef][PubMed]
    • Veiga, S.; Azcoitia, I.; Garcia-Segura, L.M. Ro5-4864, a peripheral benzodiazepine receptor ligand, reduces reactive gliosis and protects hippocampal hilar neurons from kainic acid excitotoxicity. J. Neurosci. Res. 2005, 80, 129–137. [CrossRef][PubMed]
    • (2005) J. Neurosci. Res , vol.80 , pp. 129-137
    • Veiga, S.1    Azcoitia, I.2    Garcia-Segura, L.M.3
  • 42
    • 34648828256 scopus 로고    scopus 로고
    • Translocator protein 18 kDa is involved in the regulation of reactive gliosis
    • [CrossRef][PubMed]
    • Veiga, S.; Carrero, P.; Pernia, O.; Azcoitia, I.; Garcia-Segura, L.M. Translocator protein 18 kDa is involved in the regulation of reactive gliosis. Glia 2007, 55, 1426–1436. [CrossRef][PubMed]
    • (2007) Glia , vol.55 , pp. 1426-1436
    • Veiga, S.1    Carrero, P.2    Pernia, O.3    Azcoitia, I.4    Garcia-Segura, L.M.5
  • 44
    • 84871318150 scopus 로고    scopus 로고
    • TSPO-specific ligand vinpocetine exerts a neuroprotective effect by suppressing microglial inflammation
    • [CrossRef][PubMed]
    • Zhao, Y.Y.; Yu, J.Z.; Li, Q.Y.; Ma, C.G.; Lu, C.Z.; Xiao, B.G. TSPO-specific ligand vinpocetine exerts a neuroprotective effect by suppressing microglial inflammation. Neuron Glia Biol. 2011, 7, 187–197. [CrossRef][PubMed]
    • (2011) Neuron Glia Biol , vol.7 , pp. 187-197
    • Zhao, Y.Y.1    Yu, J.Z.2    Li, Q.Y.3    Ma, C.G.4    Lu, C.Z.5    Xiao, B.G.6
  • 46
    • 84954133252 scopus 로고    scopus 로고
    • TSPO ligand residence time: A new parameter to predict compound neurosteroidogenic efficacy
    • [CrossRef][PubMed]
    • Costa, B.; da Pozzo, E.; Giacomelli, C.; Barresi, E.; Taliani, S.; da Settimo, F.; Martini, C. TSPO ligand residence time: A new parameter to predict compound neurosteroidogenic efficacy. Sci. Rep. 2016, 6. [CrossRef][PubMed]
    • (2016) Sci. Rep
    • Costa, B.1    Da Pozzo, E.2    Giacomelli, C.3    Barresi, E.4    Taliani, S.5    Da Settimo, F.6    Martini, C.7
  • 47
    • 77956909003 scopus 로고    scopus 로고
    • Proliferation inhibition, DNA damage, and cell-cycle arrest of human astrocytoma cells after acrylamide exposure
    • [CrossRef][PubMed]
    • Chen, J.H.; Tsou, T.C.; Chiu, I.M.; Chou, C.C. Proliferation inhibition, DNA damage, and cell-cycle arrest of human astrocytoma cells after acrylamide exposure. Chem. Res. Toxicol. 2010, 23, 1449–1458. [CrossRef][PubMed]
    • (2010) Chem. Res. Toxicol , vol.23 , pp. 1449-1458
    • Chen, J.H.1    Tsou, T.C.2    Chiu, I.M.3    Chou, C.C.4
  • 48
    • 84903310597 scopus 로고    scopus 로고
    • Mechanisms of U87 astrocytoma cell uptake and trafficking of monomeric versus protofibril Alzheimer’s disease amyloid-˜ proteins
    • [CrossRef][PubMed]
    • Li, Y.; Cheng, D.; Cheng, R.; Zhu, X.; Wan, T.; Liu, J.; Zhang, R. Mechanisms of U87 astrocytoma cell uptake and trafficking of monomeric versus protofibril Alzheimer’s disease amyloid-˜ proteins. PLoS ONE 2014, 9, e99939. [CrossRef][PubMed]
    • (2014) Plos ONE , vol.9
    • Li, Y.1    Cheng, D.2    Cheng, R.3    Zhu, X.4    Wan, T.5    Liu, J.6    Zhang, R.7
  • 49
    • 84939963747 scopus 로고    scopus 로고
    • Haptoglobin modulates ˜-amyloid uptake by U-87 MG astrocyte cell line
    • [CrossRef][PubMed]
    • Maresca, B.; Spagnuolo, M.S.; Cigliano, L. Haptoglobin modulates ˜-amyloid uptake by U-87 MG astrocyte cell line. J. Mol. Neurosci. 2015, 56, 35–47. [CrossRef][PubMed]
    • (2015) J. Mol. Neurosci , vol.56 , pp. 35-47
    • Maresca, B.1    Spagnuolo, M.S.2    Cigliano, L.3
  • 51
    • 52449100136 scopus 로고    scopus 로고
    • Anxiolytic-like effects of N,N-dialkyl-2-phenylindol-3-ylglyoxylamides by modulation of translocator protein promoting neurosteroid biosynthesis
    • [CrossRef][PubMed]
    • Da Settimo, F.; Simorini, F.; Taliani, S.; La Motta, C.; Marini, A.M.; Salerno, S.; Bellandi, M.; Novellino, E.; Greco, G.; Cosimelli, B. et al. Anxiolytic-like effects of N,N-dialkyl-2-phenylindol-3-ylglyoxylamides by modulation of translocator protein promoting neurosteroid biosynthesis. J. Med. Chem. 2008, 51, 5798–5806. [CrossRef][PubMed]
    • (2008) J. Med. Chem , vol.51 , pp. 5798-5806
    • Da Settimo, F.1    Simorini, F.2    Taliani, S.3    La Motta, C.4    Marini, A.M.5    Salerno, S.6    Bellandi, M.7    Novellino, E.8    Greco, G.9    Cosimelli, B.10
  • 53
    • 52449091083 scopus 로고    scopus 로고
    • Ligands of the mitochondrial 18 kDa translocator protein attenuate apoptosis of human glioblastoma cells exposed to erucylphosphohomocholine
    • [PubMed]
    • Kugler, W.; Veenman, L.; Shandalov, Y.; Leschiner, S.; Spanier, I.; Lakomek, M.; Gavish, M. Ligands of the mitochondrial 18 kDa translocator protein attenuate apoptosis of human glioblastoma cells exposed to erucylphosphohomocholine. Cell Oncol. 2008, 30, 435–450. [PubMed]
    • (2008) Cell Oncol , vol.30 , pp. 435-450
    • Kugler, W.1    Veenman, L.2    Shandalov, Y.3    Leschiner, S.4    Spanier, I.5    Lakomek, M.6    Gavish, M.7
  • 56
    • 0036161924 scopus 로고    scopus 로고
    • Substrate-dependence of reduction of MTT: A tetrazolium dye differs in cultured astroglia and neurons. Neurochem
    • [CrossRef]
    • Takahashi, S.; Abe, T.; Gotoh, J.; Fukuuchi, Y. Substrate-dependence of reduction of MTT: A tetrazolium dye differs in cultured astroglia and neurons. Neurochem. Int. 2002, 40, 441–448. [CrossRef]
    • (2002) Int , vol.40 , pp. 441-448
    • Takahashi, S.1    Abe, T.2    Gotoh, J.3    Fukuuchi, Y.4
  • 57
    • 0029116823 scopus 로고
    • Aqueous soluble tetrazolium/formazan MTS as an indicator of NADH- and NADPH-dependent dehydrogenase activity
    • [PubMed]
    • Dunigan, D.D.; Waters, S.B.; Owen, T.C. Aqueous soluble tetrazolium/formazan MTS as an indicator of NADH- and NADPH-dependent dehydrogenase activity. Biotechniques 1995, 19, 640–649. [PubMed]
    • (1995) Biotechniques , vol.19 , pp. 640-649
    • Dunigan, D.D.1    Waters, S.B.2    Owen, T.C.3
  • 58
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • [CrossRef]
    • Mosmann, T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65, 55–63. [CrossRef]
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 59
    • 0026649978 scopus 로고
    • Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: Regulation by a mitochondrial diazepam binding inhibitor receptor
    • [CrossRef][PubMed]
    • Papadopoulos, V.; Guarneri, P.; Kreuger, K.E.; Guidotti, A.; Costa, E. Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: Regulation by a mitochondrial diazepam binding inhibitor receptor. Proc. Natl. Acad. Sci. USA 1992, 89, 5113–5117. [CrossRef][PubMed]
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5113-5117
    • Papadopoulos, V.1    Guarneri, P.2    Kreuger, K.E.3    Guidotti, A.4    Costa, E.5
  • 60
    • 1342309158 scopus 로고    scopus 로고
    • Aromatase expression by reactive astroglia is neuroprotective
    • [CrossRef][PubMed]
    • Azcoitia, I.; Sierra, A.; Veiga, S.; Garcia-Segura, L.M. Aromatase expression by reactive astroglia is neuroprotective. Ann. N. Y. Acad. Sci. 2003, 1007, 298–305. [CrossRef][PubMed]
    • (2003) Ann. N. Y. Acad. Sci , vol.1007 , pp. 298-305
    • Azcoitia, I.1    Sierra, A.2    Veiga, S.3    Garcia-Segura, L.M.4
  • 62
    • 17844407395 scopus 로고    scopus 로고
    • Glia-neuron crosstalk in the neuroprotective mechanisms of sex steroid hormones
    • [CrossRef][PubMed]
    • Garcia-Ovejero, D.; Azcoitia, I.; Doncarlos, L.L.; Melcangi, R.C.; Garcia-Segura, L.M. Glia-neuron crosstalk in the neuroprotective mechanisms of sex steroid hormones. Brain Res. Rev. 2005, 48, 273–286. [CrossRef][PubMed]
    • (2005) Brain Res. Rev , vol.48 , pp. 273-286
    • Garcia-Ovejero, D.1    Azcoitia, I.2    Doncarlos, L.L.3    Melcangi, R.C.4    Garcia-Segura, L.M.5
  • 63
    • 14144251963 scopus 로고    scopus 로고
    • Influence of gonadal steroids on the glial fibrillary acidic protein-immunoreactive astrocyte population in young rat hippocampus
    • [CrossRef][PubMed]
    • Conejo, N.M.; González-Pardo, H.; Cimadevilla, J.M.; Argüelles, J.A.; Díaz, F.; Vallejo-Seco, G.; Arias, J.L. Influence of gonadal steroids on the glial fibrillary acidic protein-immunoreactive astrocyte population in young rat hippocampus. J. Neurosci. Res. 2005, 79, 488–494. [CrossRef][PubMed]
    • (2005) J. Neurosci. Res , vol.79 , pp. 488-494
    • Conejo, N.M.1    González-Pardo, H.2    Cimadevilla, J.M.3    Argüelles, J.A.4    Díaz, F.5    Vallejo-Seco, G.6    Arias, J.L.7
  • 64
    • 34249994344 scopus 로고    scopus 로고
    • Testosterone decreases reactive astroglia and reactive microglia after brain injury in male rats: Role of its metabolites, oestradiol and dihydrotestosterone
    • [CrossRef][PubMed]
    • Barreto, G.; Veiga, S.; Azcoitia, I.; Garcia-Segura, L.M.; Garcia-Ovejero, D. Testosterone decreases reactive astroglia and reactive microglia after brain injury in male rats: Role of its metabolites, oestradiol and dihydrotestosterone. Eur. J. Neurosci. 2007, 25, 3039–3046. [CrossRef][PubMed]
    • (2007) Eur. J. Neurosci , vol.25 , pp. 3039-3046
    • Barreto, G.1    Veiga, S.2    Azcoitia, I.3    Garcia-Segura, L.M.4    Garcia-Ovejero, D.5
  • 65
    • 40749106098 scopus 로고    scopus 로고
    • Effects of estrogen on lifespan and motor functions in female hSOD1 G93A transgenic mice
    • [CrossRef][PubMed]
    • Choi, C.I.; Lee, Y.D.; Gwag, B.J.; Cho, S.I.; Kim, S.S.; Suh-Kim, H. Effects of estrogen on lifespan and motor functions in female hSOD1 G93A transgenic mice. J. Neurol. Sci. 2008, 268, 40–47. [CrossRef][PubMed]
    • (2008) J. Neurol. Sci , vol.268 , pp. 40-47
    • Choi, C.I.1    Lee, Y.D.2    Gwag, B.J.3    Cho, S.I.4    Kim, S.S.5    Suh-Kim, H.6
  • 68
    • 0032986996 scopus 로고    scopus 로고
    • The endozepine ODN stimulates [3H]thymidine incorporation in cultured rat astrocytes
    • [CrossRef]
    • Gandolfo, P.; Patte, C.; Thoumas, J.L.; Leprince, J.; Vaudry, H.; Tonon, M.C. The endozepine ODN stimulates [3H]thymidine incorporation in cultured rat astrocytes. Neuropharmacology 1999, 38, 725–732. [CrossRef]
    • (1999) Neuropharmacology , vol.38 , pp. 725-732
    • Gandolfo, P.1    Patte, C.2    Thoumas, J.L.3    Leprince, J.4    Vaudry, H.5    Tonon, M.C.6
  • 69
    • 0033914654 scopus 로고    scopus 로고
    • The triakontatetraneuropeptide (TTN) stimulates thymidine incorporation in rat astrocytes through peripheral-type benzodiazepine receptors
    • [CrossRef][PubMed]
    • Gandolfo, P.; Patte, C.; Leprince, J.; Régo, J.L.; Mensah-Nyagan, A.G.; Vaudry, H.; Tonon, M.C. The triakontatetraneuropeptide (TTN) stimulates thymidine incorporation in rat astrocytes through peripheral-type benzodiazepine receptors. J. Neurochem. 2000, 75, 701–707. [CrossRef][PubMed]
    • (2000) J. Neurochem , vol.75 , pp. 701-707
    • Gandolfo, P.1    Patte, C.2    Leprince, J.3    Régo, J.L.4    Mensah-Nyagan, A.G.5    Vaudry, H.6    Tonon, M.C.7
  • 70
    • 0028900452 scopus 로고
    • Inhibition of growth factor-induced DNA synthesis in astrocytes by ligands of peripheral-type benzodiazepine receptors
    • [CrossRef]
    • Neary, J.T.; Jorgensen, S.L.; Oracion, A.M.; Bruce, J.H.; Norenberg, M.D. Inhibition of growth factor-induced DNA synthesis in astrocytes by ligands of peripheral-type benzodiazepine receptors. Brain Res. 1995, 675, 27–30. [CrossRef]
    • (1995) Brain Res , vol.675 , pp. 27-30
    • Neary, J.T.1    Jorgensen, S.L.2    Oracion, A.M.3    Bruce, J.H.4    Norenberg, M.D.5
  • 71
    • 0026074979 scopus 로고
    • Peripheral-type benzodiazepines inhibit proliferation of astrocytes in culture
    • [CrossRef]
    • Bruce, J.H.; Ramirez, A.M.; Lin, L.; Oracion, A.; Agarwal, R.P.; Norenberg, M.D. Peripheral-type benzodiazepines inhibit proliferation of astrocytes in culture. Brain Res. 1991, 564, 167–170. [CrossRef]
    • (1991) Brain Res , vol.564 , pp. 167-170
    • Bruce, J.H.1    Ramirez, A.M.2    Lin, L.3    Oracion, A.4    Agarwal, R.P.5    Norenberg, M.D.6
  • 72
    • 0025021503 scopus 로고
    • Stimulation of cell growth and DNA synthesis by peripheral benzodiazepine
    • [CrossRef]
    • Ikezaki, K.; Black, K.L. Stimulation of cell growth and DNA synthesis by peripheral benzodiazepine. Cancer Lett. 1990, 49, 115–120. [CrossRef]
    • (1990) Cancer Lett , vol.49 , pp. 115-120
    • Ikezaki, K.1    Black, K.L.2
  • 73
    • 0033567438 scopus 로고    scopus 로고
    • Effect of 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinoline carboxamide (PK11195), a specific ligand of the peripheral benzodiazepine receptor, on the lipid fluidity of mitochondria in human glioma cells
    • [CrossRef]
    • Miccoli, L.; Oudard, S.; Beurdeley-Thomas, A.; Dutrillaux, B.; Poupon, M.F. Effect of 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinoline carboxamide (PK11195), a specific ligand of the peripheral benzodiazepine receptor, on the lipid fluidity of mitochondria in human glioma cells. Biochem. Pharmacol. 1999, 58, 715–721. [CrossRef]
    • (1999) Biochem. Pharmacol , vol.58 , pp. 715-721
    • Miccoli, L.1    Oudard, S.2    Beurdeley-Thomas, A.3    Dutrillaux, B.4    Poupon, M.F.5
  • 74
    • 0025786190 scopus 로고
    • Peripheral benzodiazepine induces morphological changes and proliferation of mitochondria in glioma cells. J
    • [CrossRef][PubMed]
    • Shiraishi, T.; Black, K.L.; Ikezaki, K.; Becker, D.P. Peripheral benzodiazepine induces morphological changes and proliferation of mitochondria in glioma cells. J. Neurosci. Res. 1991, 30, 463–474. [CrossRef][PubMed]
    • (1991) Neurosci. Res , vol.30 , pp. 463-474
    • Shiraishi, T.1    Black, K.L.2    Ikezaki, K.3    Becker, D.P.4
  • 75
    • 0028224113 scopus 로고
    • Peripheral benzodiazepine stimulates secretion of growth hormone and mitochondrial proliferation in pituitary tumour GH3 cells
    • [PubMed]
    • Black, K.L.; Shiraishi, T.; Ikezak, K.; Tabuchi, K.; Becker, D.P. Peripheral benzodiazepine stimulates secretion of growth hormone and mitochondrial proliferation in pituitary tumour GH3 cells. Neurol. Res. 1994, 16, 74–80. [PubMed]
    • (1994) Neurol. Res , vol.16 , pp. 74-80
    • Black, K.L.1    Shiraishi, T.2    Ikezak, K.3    Tabuchi, K.4    Becker, D.P.5
  • 76
    • 84860312483 scopus 로고    scopus 로고
    • Is there any correlation between binding and functional effects at the translocator protein (TSPO) (18 kDa)
    • [CrossRef][PubMed]
    • Scarf, A.M.; Auman, K.M.; Kassiou, M. Is there any correlation between binding and functional effects at the translocator protein (TSPO) (18 kDa)? Curr. Mol. Med. 2012, 12, 387–397. [CrossRef][PubMed]
    • (2012) Curr. Mol. Med , vol.12 , pp. 387-397
    • Scarf, A.M.1    Auman, K.M.2    Kassiou, M.3
  • 77
    • 0028000402 scopus 로고
    • Expression of mitochondrial benzodiazepine receptor and its putative endogenous ligand diazepam binding inhibitor in cultured primary astrocytes and C-6 cells
    • [PubMed]
    • Alho, H.; Varga, V.; Krueger, K.E. Expression of mitochondrial benzodiazepine receptor and its putative endogenous ligand diazepam binding inhibitor in cultured primary astrocytes and C-6 cells: Relation to cell growth. Cell Growth Differ. 1994, 5, 1005–1014. [PubMed]
    • (1994) Relation to Cell Growth. Cell Growth Differ , vol.5 , pp. 1005-1014
    • Alho, H.1    Varga, V.2    Krueger, K.E.3
  • 78
    • 84956721995 scopus 로고    scopus 로고
    • The effects of PK11195 on meningioma was associated with allopregnanolone biosynthesis, which was mediated by translocator protein 18 kDa
    • [CrossRef][PubMed]
    • Gao, Z.W.; Huang, J.B.; Lin, Q.; Qin, Q.; Liang, Y.J.; Zhou, L.; Luo, M. The effects of PK11195 on meningioma was associated with allopregnanolone biosynthesis, which was mediated by translocator protein 18 kDa. Cancer Biomark. 2016, 16, 65–69. [CrossRef][PubMed]
    • (2016) Cancer Biomark , vol.16 , pp. 65-69
    • Gao, Z.W.1    Huang, J.B.2    Lin, Q.3    Qin, Q.4    Liang, Y.J.5    Zhou, L.6    Luo, M.7
  • 79
    • 78651173150 scopus 로고
    • Effects of steroid hormones on gene regulation and cell metabolism
    • [CrossRef][PubMed]
    • Hechter, O.; Halkerston, I.D. Effects of steroid hormones on gene regulation and cell metabolism. Annu. Rev. Physiol. 1965, 27, 133–162. [CrossRef][PubMed]
    • (1965) Annu. Rev. Physiol , vol.27 , pp. 133-162
    • Hechter, O.1    Halkerston, I.D.2
  • 80
    • 1942520401 scopus 로고    scopus 로고
    • Astrocyte apoptosis: Implications for neuroprotection
    • [CrossRef][PubMed]
    • Takuma, K.; Baba, A.; Matsuda, T. Astrocyte apoptosis: Implications for neuroprotection. Prog. Neurobiol. 2004, 72, 111–127. [CrossRef][PubMed]
    • (2004) Prog. Neurobiol , vol.72 , pp. 111-127
    • Takuma, K.1    Baba, A.2    Matsuda, T.3
  • 81
    • 33644556491 scopus 로고    scopus 로고
    • Neuronal survival depends on EGFR signaling in cortical but not midbrain astrocytes
    • [CrossRef][PubMed]
    • Wagner, B.; Natarajan, A.; Grünaug, S.; Kroismayr, R.; Wagner, E.F.; Sibilia, M. Neuronal survival depends on EGFR signaling in cortical but not midbrain astrocytes. EMBO J. 2006, 25, 752–762. [CrossRef][PubMed]
    • (2006) EMBO J , vol.25 , pp. 752-762
    • Wagner, B.1    Natarajan, A.2    Grünaug, S.3    Kroismayr, R.4    Wagner, E.F.5    Sibilia, M.6
  • 82
    • 34547736919 scopus 로고    scopus 로고
    • Astrocytes are a specific immunological target in Rasmussen’s encephalitis
    • [CrossRef][PubMed]
    • Bauer, J.; Elger, C.E.; Hans, V.H.; Schramm, J.; Urbach, H.; Lassmann, H.; Bien, C.G. Astrocytes are a specific immunological target in Rasmussen’s encephalitis. Ann. Neurol. 2007, 62, 67–80. [CrossRef][PubMed]
    • (2007) Ann. Neurol , vol.62 , pp. 67-80
    • Bauer, J.1    Elger, C.E.2    Hans, V.H.3    Schramm, J.4    Urbach, H.5    Lassmann, H.6    Bien, C.G.7
  • 83
    • 70349469543 scopus 로고    scopus 로고
    • Astrocyte-neuron interactions in neurological disorders
    • [CrossRef][PubMed]
    • Ricci, G.; Volpi, L.; Pasquali, L.; Petrozzi, L.; Siciliano, G. Astrocyte-neuron interactions in neurological disorders. J. Biol. Phys. 2009, 35, 317–336. [CrossRef][PubMed]
    • (2009) J. Biol. Phys , vol.35 , pp. 317-336
    • Ricci, G.1    Volpi, L.2    Pasquali, L.3    Petrozzi, L.4    Siciliano, G.5
  • 84
    • 78650722767 scopus 로고    scopus 로고
    • Neuromyelitis optica spectrum disorders
    • [CrossRef][PubMed]
    • Wingerchuk, D.M. Neuromyelitis optica spectrum disorders. Continuum (Minneap. Minn.) 2010, 16, 105–121. [CrossRef][PubMed]
    • (2010) Continuum (Minneap. Minn.) , vol.16 , pp. 105-121
    • Wingerchuk, D.M.1
  • 85
    • 84884219495 scopus 로고    scopus 로고
    • Astroglial networking contributes to neurometabolic coupling
    • [CrossRef][PubMed]
    • Escartin, C.; Rouach, N. Astroglial networking contributes to neurometabolic coupling. Front. Neuroenerg. 2013, 5. [CrossRef][PubMed]
    • (2013) Front. Neuroenerg
    • Escartin, C.1    Rouach, N.2


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