Ovariectomy and 17β-estradiol modulate disease progression of a mouse model of ALS

Brain Research

Volumn 1021, Issue 1, 2004, Pages 128-131

  Groeneveld, G J ^a   Van Muiswinkel, F L ^a   Sturkenboom, J M ^a   Wokke, J H J ^a   Bar P R ^a   Van Den Berg, L H ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Anti oxidative; Degenerative diseases; Disorders of the nervous system; E2; G93A; Gonadal hormone; MND

Indexed keywords

ESTRADIOL; COPPER ZINC SUPEROXIDE DISMUTASE; NEUROPROTECTIVE AGENT; SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG MEGADOSE; ESTROGEN ACTIVITY; FEMALE; MOUSE; NONHUMAN; OVARIECTOMY; POSTMENOPAUSE; PRIORITY JOURNAL; TRANSGENIC MOUSE; ANIMAL; DISEASE MODEL; GENETICS; HUMAN; PATHOLOGY; PATHOPHYSIOLOGY; PHENOTYPE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ESTRADIOL; FEMALE; HUMANS; MICE; MICE, TRANSGENIC; NEUROPROTECTIVE AGENTS; OVARIECTOMY; PHENOTYPE; SUPEROXIDE DISMUTASE;

EID: 4344567018     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2004.06.024     Document Type: Article

References (22)

1. Bär P.R., Amelink G.J. Protection against muscle damage exerted by oestrogen: hormonal or antioxidant action? Biochem. Soc. Trans. 25:1997;50-54
2. Barneoud P., Lolivier J., Sanger D.J., Scatton B., Moser P. Quantitative motor assessment in FALS mice: a longitudinal study. NeuroReport. 8:1997;2861-2865
3. Behl C. Oestrogen as a neuroprotective hormone. Nat. Rev., Neurosci. 3:2002;433-442
4. Belcredito S., Vegeto E., Brusadelli A., Ghisletti S., Mussi P., Ciana P., Maggi A. Estrogen neuroprotection: the involvement of the Bcl-2 binding protein BNIP2. Brain. Res. Brain. Res. Rev. 37:2001;335-342
5. Chio A., Meineri P., Tribolo A., Schiffer D. Risk factors in motor neuron disease: a case-control study. Neuroepidemiology. 10:1991;174-184
6. Gelinas S., Martinoli M.G. Neuroprotective effect of estradiol and phytoestrogens on MPP+-induced cytotoxicity in neuronal PC12 cells. J. Neurosci. Res. 70:2002;90-96
7. Gordon M.N., Osterburg H.H., May P.C., Finch C.E. Effective oral administration of 17 beta-estradiol to female C57BL/6J mice through the drinking water. Biol. Reprod. 35:1986;1088-1095
8. Gurney M.E., Pu H., Chiu A.Y., Dal Canto M.C., Polchow C.Y., Alexander D.D., Caliendo J., Hentati A., Kwon Y.W., Deng H.X., Chen W., Zhai P., Sufit R.L., Siddique T. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science. 264:1994;1772-1775
9. Gurney M.E., Cutting F.B., Zhai P., Doble A., Taylor C.P., Andrus P.K., Hall E.D. Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann. Neurol. 39(2):1996 (Feb.);147-157
10. Haverkamp L.J., Appel V., Appel S.H. Natural history of amyotrophic lateral sclerosis in a database population. Validation of a scoring system and a model for survival prediction. Brain. 118:1995;707-719
11. Hurn P.D., Brass L.M. Estrogen and stroke: a balanced analysis. Stroke. 34:2003;338-341
12. Islamov R.R., Hendricks W.A., Jones R.J., Lyall G.J., Spanier N.S., Murashov A.K. 17Beta-estradiol stimulates regeneration of sciatic nerve in female mice. Brain Res. 943:2002;283-286
13. Klivenyi P., Ferrante R.J., Matthews R.T., Bogdanov M.B., Klein A.M., Andreassen O.A., Mueller G., Wermer M., Kaddurah-Daouk R., Beal M.F. Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. Nat. Med. 5(3):1999 (Mar.);347-350
14. Kruman I.I., Pedersen W.A., Springer J.E., Mattson M.P. ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons by a mechanism involving increased oxidative stress and a perturbed calcium homeostasis. Exp. Neurol. 160:1999;28-39
15. Li M., Ona V.O., Guegan C., Chen M., Jackson-Lewis V., Andrews L.J., Olszewski A.J., Stieg P.E., Lee J.P., Przedborski S., Friedlander R.M. Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. Science. 288(5464):2000 (Apr. 14);335-339
16. Liu R., Yang S.H., Perez E., Yi K.D., Wu S.S., Eberst K., Prokai L., Prokai-Tatrai K., Cai Z.Y., Covey D.F., Day A.L., Simpkins J.W. Neuroprotective effects of a novel non-receptor-binding estrogen analogue: in vitro and in vivo analysis. Stroke. 33:2002;2485-2491
17. Nakamizo T., Urushitani M., Inoue R., Shinohara A., Sawada H., Honda K., Kihara T., Akaike A., Shimohama S. Protection of cultured spinal motor neurons by estradiol. NeuroReport. 11:2000;3493-3497
18. Nilsen J., Brinton R.D. Impact of progestins on estrogen-induced neuroprotection: synergy by progesterone and 19-norprogesterone and antagonism by medroxyprogesterone acetate. Endocrinology. 143:2002;205-212
19. Petanceska S.S., Nagy V., Frail D., Gandy S. Ovariectomy and 17beta-etradiol modulate the levels of Alzheimer's amyloid beta-peptides in brain. Neurology. 54:2000;2212-2217
20. Rosen D.R. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature. 364:1993;362
21. Van den Bosch L., Tilkin P., Lemmens G., Robberecht W. Minocycline delays disease onset and mortality in a transgenic model of ALS. Neuroreport. 13(8):2002 (Jun. 12);1067-1070
22. Veldink J.H., Bär P.R., Joosten E.A., Otten M., Wokke J.H., van den Berg L.H. Sexual differences in onset of disease and response to exercise in a transgenic model of ALS. Neuromuscul. Disord. 13:2003;737-743