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Volumn 11, Issue 8, 2016, Pages 588-602

Aberrant DNA methylation of WNT pathway genes in the development and progression of CIMP-negative colorectal cancer

Author keywords

Adenoma; APC; colorectal cancer; gene expression; promoter and gene body methylation; whole methylome analysis; WNT signaling pathway; catenin mutation

Indexed keywords

ADENOMA; ADULT; AGED; ARTICLE; AXIN2 GENE; CACYBP GENE; CANCER GROWTH; CHP1 GENE; COLORECTAL CANCER; CONTROLLED STUDY; CTNNB1 GENE; DKK1 GENE; DNA ISOLATION; DNA METHYLATION; FEMALE; GENE EXPRESSION; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MIDDLE AGED; MUTATIONAL ANALYSIS; ONCOGENE MYC; POLYMERASE CHAIN REACTION; PRICKLE1 GENE; PROMOTER REGION; SEQUENCE ANALYSIS; SFRP1 GENE; SFRP2 GENE; SOX17 GENE; TUMOR LOCALIZATION; VANGL1 GENE; WNT SIGNALING PATHWAY; WNT5A GENE; COLORECTAL TUMOR; GENE LOCUS; GENETICS; HUMAN GENOME; METABOLISM; PATHOLOGY;

EID: 84976532755     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.1080/15592294.2016.1190894     Document Type: Article
Times cited : (64)

References (66)
  • 2
    • 84866235428 scopus 로고    scopus 로고
    • Genetic and epigenetic events generate multiple pathways in colorectal cancer progression
    • 22888469
    • M.Pancione, A.Remo, V.Colantuoni. Genetic and epigenetic events generate multiple pathways in colorectal cancer progression. Patholog Res Int 2012; 2012:509348; PMID:22888469; http://dx.doi.org/10.1155/2012/509348
    • (2012) Patholog Res Int , vol.2012 , pp. 509348
    • Pancione, M.1    Remo, A.2    Colantuoni, V.3
  • 3
    • 84885008597 scopus 로고    scopus 로고
    • Genome-wide screening for understanding the role of DNA methylation in colorectal cancer
    • 24059802
    • F.Sipos, G.Mũzes, A.V.Patai, I.Fũri, B.Péterfia, P.Hollósi, B.Molnár, Z.Tulassay. Genome-wide screening for understanding the role of DNA methylation in colorectal cancer. Epigenomics 2013; 5:569-81; PMID:24059802; http://dx.doi.org/10.2217/epi.13.52
    • (2013) Epigenomics , vol.5 , pp. 569-581
    • Sipos, F.1    Mũzes, G.2    Patai, A.V.3    Fũri, I.4    Péterfia, B.5    Hollósi, P.6    Molnár, B.7    Tulassay, Z.8
  • 4
    • 84862861689 scopus 로고    scopus 로고
    • Role of DNA methylation in colorectal carcinogenesis
    • 22722557
    • A.V.Patai, B.Molnár, A.Kalmár, A.Schöller, K.Tóth, Z.Tulassay. Role of DNA methylation in colorectal carcinogenesis. Dig Dis 2012; 30:310-5; PMID:22722557; http://dx.doi.org/10.1159/000337004
    • (2012) Dig Dis , vol.30 , pp. 310-315
    • Patai, A.V.1    Molnár, B.2    Kalmár, A.3    Schöller, A.4    Tóth, K.5    Tulassay, Z.6
  • 5
    • 77349107376 scopus 로고    scopus 로고
    • DNA methylation markers in colorectal cancer
    • 20135198
    • M.S.Kim, J.Lee, D.Sidransky. DNA methylation markers in colorectal cancer. Cancer Metastasis Rev 2010; 29:181-206; PMID:20135198; http://dx.doi.org/10.1007/s10555-010-9207-6
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 181-206
    • Kim, M.S.1    Lee, J.2    Sidransky, D.3
  • 6
    • 84873691159 scopus 로고    scopus 로고
    • Serrated pathway: alternative route to colorectal cancer
    • 23431044
    • A.V.Patai, B.Molnár, Z.Tulassay, F.Sipos. Serrated pathway:alternative route to colorectal cancer. World J Gastroenterol 2013; 19:607-15; PMID:23431044; http://dx.doi.org/10.3748/wjg.v19.i5.607
    • (2013) World J Gastroenterol , vol.19 , pp. 607-615
    • Patai, A.V.1    Molnár, B.2    Tulassay, Z.3    Sipos, F.4
  • 7
    • 10344260184 scopus 로고    scopus 로고
    • CpG island methylator phenotype in cancer
    • 15573120
    • J.P.Issa. CpG island methylator phenotype in cancer. Nat Rev Cancer 2004; 4:988-93; PMID:15573120; http://dx.doi.org/10.1038/nrc1507
    • (2004) Nat Rev Cancer , vol.4 , pp. 988-993
    • Issa, J.P.1
  • 8
    • 84863986133 scopus 로고    scopus 로고
    • Functions of DNA methylation: islands, start sites, gene bodies and beyond
    • 22641018
    • P.A.Jones. Functions of DNA methylation:islands, start sites, gene bodies and beyond. Nat Rev Genet 2012; 13:484-92; PMID:22641018; http://dx.doi.org/10.1038/nrg3230
    • (2012) Nat Rev Genet , vol.13 , pp. 484-492
    • Jones, P.A.1
  • 9
    • 84907997839 scopus 로고    scopus 로고
    • Gene body methylation can alter gene expression and is a therapeutic target in cancer
    • 25263941
    • X.Yang, H.Han, D.D.De Carvalho, F.D.Lay, P.A.Jones, G.Liang. Gene body methylation can alter gene expression and is a therapeutic target in cancer. Cancer Cell 2014; 26:577-90; PMID:25263941; http://dx.doi.org/10.1016/j.ccr.2014.07.028
    • (2014) Cancer Cell , vol.26 , pp. 577-590
    • Yang, X.1    Han, H.2    De Carvalho, D.D.3    Lay, F.D.4    Jones, P.A.5    Liang, G.6
  • 10
    • 33845373278 scopus 로고    scopus 로고
    • Colorectal cancer and genetic alterations in the Wnt pathway
    • 17143297
    • S.Segditsas, I.Tomlinson. Colorectal cancer and genetic alterations in the Wnt pathway. Oncogene 2006; 25:7531-7; PMID:17143297; http://dx.doi.org/10.1038/sj.onc.1210059
    • (2006) Oncogene , vol.25 , pp. 7531-7537
    • Segditsas, S.1    Tomlinson, I.2
  • 11
    • 84924352552 scopus 로고    scopus 로고
    • Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists
    • 25432628
    • A.L.Silva, S.N.Dawson, M.J.Arends, K.Guttula, N.Hall, E.A.Cameron, T.H.Huang, J.D.Brenton, S.Tavaré, M.Bienz, et al. Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists. BMC Cancer 2014; 14:891; PMID:25432628; http://dx.doi.org/10.1186/1471-2407-14-891
    • (2014) BMC Cancer , vol.14 , pp. 891
    • Silva, A.L.1    Dawson, S.N.2    Arends, M.J.3    Guttula, K.4    Hall, N.5    Cameron, E.A.6    Huang, T.H.7    Brenton, J.D.8    Tavaré, S.9    Bienz, M.10
  • 12
    • 84919847901 scopus 로고    scopus 로고
    • Aberrant promoter methylation of the SFRP1 gene may contribute to colorectal carcinogenesis: a meta-analysis
    • 24929326
    • Y.Z.Chen, D.Liu, Y.X.Zhao, H.T.Wang, Y.Gao, Y.Chen. Aberrant promoter methylation of the SFRP1 gene may contribute to colorectal carcinogenesis:a meta-analysis. Tumour Biol 2014; 35:9201-10; PMID:24929326; http://dx.doi.org/10.1007/s13277-014-2180-x
    • (2014) Tumour Biol , vol.35 , pp. 9201-9210
    • Chen, Y.Z.1    Liu, D.2    Zhao, Y.X.3    Wang, H.T.4    Gao, Y.5    Chen, Y.6
  • 15
    • 84922394857 scopus 로고    scopus 로고
    • Variation risks of SFRP2 hypermethylation between precancerous disease and colorectal cancer
    • 25053594
    • C.Sui, G.Wang, Q.Chen, J.Ma. Variation risks of SFRP2 hypermethylation between precancerous disease and colorectal cancer. Tumour Biol 2014; 35:10457-65; PMID:25053594; http://dx.doi.org/10.1007/s13277-014-2313-2
    • (2014) Tumour Biol , vol.35 , pp. 10457-10465
    • Sui, C.1    Wang, G.2    Chen, Q.3    Ma, J.4
  • 16
    • 84907061280 scopus 로고    scopus 로고
    • Promoter methylation analysis of WNT/β-catenin pathway regulators and its association with expression of DNMT1 enzyme in colorectal cancer
    • 25107489
    • N.M.Samaei, Y.Yazdani, R.Alizadeh-Navaei, H.Azadeh, T.Farazmandfar. Promoter methylation analysis of WNT/β-catenin pathway regulators and its association with expression of DNMT1 enzyme in colorectal cancer. J Biomed Sci 2014; 21:73; PMID:25107489; http://dx.doi.org/10.1186/s12929-014-0073-3
    • (2014) J Biomed Sci , vol.21 , pp. 73
    • Samaei, N.M.1    Yazdani, Y.2    Alizadeh-Navaei, R.3    Azadeh, H.4    Farazmandfar, T.5
  • 17
    • 84942897786 scopus 로고    scopus 로고
    • Comprehensive DNA methylation analysis reveals a common ten-gene methylation signature in colorectal adenomas and carcinomas
    • 26291085
    • Á.V.Patai, G.Valcz, P.Hollósi, A.Kalmár, B.Péterfia, Á.Patai, B.Wichmann, S.Spisák, B.K.Barták, K.Leiszter, et al. Comprehensive DNA methylation analysis reveals a common ten-gene methylation signature in colorectal adenomas and carcinomas. PLoS One 2015; 10:e0133836; PMID:26291085; http://dx.doi.org/10.1371/journal.pone.0133836
    • (2015) PLoS One , vol.10 , pp. 0133836
    • Patai, Á.V.1    Valcz, G.2    Hollósi, P.3    Kalmár, A.4    Péterfia, B.5    Patai, Á.6    Wichmann, B.7    Spisák, S.8    Barták, B.K.9    Leiszter, K.10
  • 18
    • 84945182799 scopus 로고    scopus 로고
    • DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer
    • A.Kalmár, B.Péterfia, P.Hollósi, O.Galamb, S.Spisák, B.Wichmann, A.Bodor, K.Tóth, Á.V.Patai, G.Valcz, et al. DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer. BMC Cancer 2015; 15:736; PMID:26482433; http://dx.doi.org/10.1186/s12885-015-1687-x
    • (2015) BMC Cancer , vol.15 , pp. 736
    • Kalmár, A.1    Péterfia, B.2    Hollósi, P.3    Galamb, O.4    Spisák, S.5    Wichmann, B.6    Bodor, A.7    Tóth, K.8    Patai, Á.V.9    Valcz, G.10
  • 20
    • 84900412412 scopus 로고    scopus 로고
    • DNA methylation changes in genes frequently mutated in sporadic colorectal cancer and in the DNA repair and Wnt/β-catenin signaling pathway genes
    • 24811787
    • S.A.Farkas, V.Vymetalkova, L.Vodickova, P.Vodicka, T.K.Nilsson. DNA methylation changes in genes frequently mutated in sporadic colorectal cancer and in the DNA repair and Wnt/β-catenin signaling pathway genes. Epigenomics 2014; 6:179-91; PMID:24811787; http://dx.doi.org/10.2217/epi.14.7
    • (2014) Epigenomics , vol.6 , pp. 179-191
    • Farkas, S.A.1    Vymetalkova, V.2    Vodickova, L.3    Vodicka, P.4    Nilsson, T.K.5
  • 22
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • 22810696
    • Cancer Genome Atlas Network. Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012; 487:330-7; PMID:22810696; http://dx.doi.org/10.1038/nature11252
    • (2012) Nature , vol.487 , pp. 330-337
  • 23
    • 84920647010 scopus 로고    scopus 로고
    • Distinct WNT/β-catenin signaling activation in the serrated neoplasia pathway and the adenoma-carcinoma sequence of the colorectum
    • 24925057
    • T.Murakami, H.Mitomi, T.Saito, M.Takahashi, N.Sakamoto, N.Fukui, T.Yao, S.Watanabe. Distinct WNT/β-catenin signaling activation in the serrated neoplasia pathway and the adenoma-carcinoma sequence of the colorectum. Mod Pathol 2015; 28:146-58; PMID:24925057; http://dx.doi.org/10.1038/modpathol.2014.41
    • (2015) Mod Pathol , vol.28 , pp. 146-158
    • Murakami, T.1    Mitomi, H.2    Saito, T.3    Takahashi, M.4    Sakamoto, N.5    Fukui, N.6    Yao, T.7    Watanabe, S.8
  • 25
    • 84902946950 scopus 로고    scopus 로고
    • DNA methylation alterations of AXIN2 in serrated adenomas and colon carcinomas with microsatellite instability
    • 24964857
    • Y.Muto, T.Maeda, K.Suzuki, T.Kato, F.Watanabe, H.Kamiyama, M.Saito, K.Koizumi, Y.Miyaki, F.Konishi, et al. DNA methylation alterations of AXIN2 in serrated adenomas and colon carcinomas with microsatellite instability. BMC Cancer 2014; 14:466; PMID:24964857; http://dx.doi.org/10.1186/1471-2407-14-466
    • (2014) BMC Cancer , vol.14 , pp. 466
    • Muto, Y.1    Maeda, T.2    Suzuki, K.3    Kato, T.4    Watanabe, F.5    Kamiyama, H.6    Saito, M.7    Koizumi, K.8    Miyaki, Y.9    Konishi, F.10
  • 26
    • 84894264390 scopus 로고    scopus 로고
    • Wif-1 methylation and β-catenin expression in colorectal serrated lesions
    • 24713243
    • Y.Fang, L.Wang, Y.Zhang, C.Ge, C.Xu. Wif-1 methylation and β-catenin expression in colorectal serrated lesions. Zhonghua Bing Li Xue Za Zhi 2014; 43:15-9; PMID:24713243; http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2014.01.004
    • (2014) Zhonghua Bing Li Xue Za Zhi , vol.43 , pp. 15-19
    • Fang, Y.1    Wang, L.2    Zhang, Y.3    Ge, C.4    Xu, C.5
  • 27
    • 84864532256 scopus 로고    scopus 로고
    • Wnt signalling pathway in the serrated neoplastic pathway of the colorectum: possible roles and epigenetic regulatory mechanisms
    • 22412046
    • X.Fu, L.Li, Y.Peng. Wnt signalling pathway in the serrated neoplastic pathway of the colorectum:possible roles and epigenetic regulatory mechanisms. J Clin Pathol 2012; 65:675-9; PMID:22412046; http://dx.doi.org/10.1136/jclinpath-2011-200602
    • (2012) J Clin Pathol , vol.65 , pp. 675-679
    • Fu, X.1    Li, L.2    Peng, Y.3
  • 28
    • 84904744663 scopus 로고    scopus 로고
    • Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer
    • 24793120
    • Y.Luo, C.J.Wong, A.M.Kaz, S.Dzieciatkowski, K.T.Carter, S.M.Morris, J.Wang, J.E.Willis, K.W.Makar, C.M.Ulrich, et al. Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer. Gastroenterology 2014; 147:418-29; PMID:24793120; http://dx.doi.org/10.1053/j.gastro.2014.04.039
    • (2014) Gastroenterology , vol.147 , pp. 418-429
    • Luo, Y.1    Wong, C.J.2    Kaz, A.M.3    Dzieciatkowski, S.4    Carter, K.T.5    Morris, S.M.6    Wang, J.7    Willis, J.E.8    Makar, K.W.9    Ulrich, C.M.10
  • 30
    • 84985009362 scopus 로고    scopus 로고
    • High-frequency aberrantly methylated targets in pancreatic adenocarcinoma identified via global DNA methylation analysis using methylCap-seq
    • 25276247
    • Y.Zhao, J.Sun, H.Zhang, S.Guo, J.Gu, W.Wang, N.Tang, X.Zhou, J.Yu. High-frequency aberrantly methylated targets in pancreatic adenocarcinoma identified via global DNA methylation analysis using methylCap-seq. Clin Epigenetics 2014; 6:18; PMID:25276247; http://dx.doi.org/10.1186/1868-7083-6-18
    • (2014) Clin Epigenetics , vol.6 , pp. 18
    • Zhao, Y.1    Sun, J.2    Zhang, H.3    Guo, S.4    Gu, J.5    Wang, W.6    Tang, N.7    Zhou, X.8    Yu, J.9
  • 31
    • 84944887096 scopus 로고    scopus 로고
    • Genome-wide DNA methylation detection by MethylCap-seq and Infinium HumanMethylation450 BeadChips: an independent large-scale comparison
    • 26482909
    • T.De Meyer, P.Bady, G.Trooskens, S.Kurscheid, J.Bloch, J.M.Kros, J.A.Hainfellner, R.Stupp, M.Delorenzi, M.E.Hegi, et al. Genome-wide DNA methylation detection by MethylCap-seq and Infinium HumanMethylation450 BeadChips:an independent large-scale comparison. Sci Rep 2015; 5:15375; PMID:26482909; http://dx.doi.org/10.1038/srep15375
    • (2015) Sci Rep , vol.5 , pp. 15375
    • De Meyer, T.1    Bady, P.2    Trooskens, G.3    Kurscheid, S.4    Bloch, J.5    Kros, J.M.6    Hainfellner, J.A.7    Stupp, R.8    Delorenzi, M.9    Hegi, M.E.10
  • 32
    • 54449092791 scopus 로고    scopus 로고
    • CpG island methylator phenotype in colorectal cancers: comparison of the new and classic CpG island methylator phenotype marker panels
    • 18834226
    • S.Lee, N.Y.Cho, E.J.Yoo, J.H.Kim, G.H.Kang. CpG island methylator phenotype in colorectal cancers:comparison of the new and classic CpG island methylator phenotype marker panels. Arch Pathol Lab Med 2008; 132:1657-65; PMID:18834226; http://dx.doi.org/10.1043/1543-2165(2008)132[1657:CIMPIC]2.0.CO;2
    • (2008) Arch Pathol Lab Med , vol.132 , pp. 1657-1665
    • Lee, S.1    Cho, N.Y.2    Yoo, E.J.3    Kim, J.H.4    Kang, G.H.5
  • 33
    • 33745541234 scopus 로고    scopus 로고
    • CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
    • 16804544
    • D.J.Weisenberger, K.D.Siegmund, M.Campan, J.Young, T.I.Long, M.A.Faasse, G.H.Kang, M.Widschwendter, D.Weener, D.Buchanan, et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet 2006; 38:787-93; PMID:16804544; http://dx.doi.org/10.1038/ng1834
    • (2006) Nat Genet , vol.38 , pp. 787-793
    • Weisenberger, D.J.1    Siegmund, K.D.2    Campan, M.3    Young, J.4    Long, T.I.5    Faasse, M.A.6    Kang, G.H.7    Widschwendter, M.8    Weener, D.9    Buchanan, D.10
  • 37
    • 78049498636 scopus 로고    scopus 로고
    • MUC12 mRNA expression is an independent marker of prognosis in stage II and stage III colorectal cancer
    • 20162577
    • T.Matsuyama, T.Ishikawa, K.Mogushi, T.Yoshida, S.Iida, H.Uetake, H.Mizushima, H.Tanaka, K.Sugihara. MUC12 mRNA expression is an independent marker of prognosis in stage II and stage III colorectal cancer. Int J Cancer 2010; 127:2292-9; PMID:20162577; http://dx.doi.org/10.1002/ijc.25256
    • (2010) Int J Cancer , vol.127 , pp. 2292-2299
    • Matsuyama, T.1    Ishikawa, T.2    Mogushi, K.3    Yoshida, T.4    Iida, S.5    Uetake, H.6    Mizushima, H.7    Tanaka, H.8    Sugihara, K.9
  • 39
    • 77957860765 scopus 로고    scopus 로고
    • Identification of an intermediate signature that marks the initial phases of the colorectal adenoma-carcinoma transition
    • 20878084
    • H.Tang, Q.Guo, C.Zhang, J.Zhu, H.Yang, Y.L.Zou, Y.Yan, D.Hong, T.Sou, X.M.Yan. Identification of an intermediate signature that marks the initial phases of the colorectal adenoma-carcinoma transition. Int J Mol Med 2010; 26:631-41; PMID:20878084; http://dx.doi.org/10.3892/ijmm_00000508
    • (2010) Int J Mol Med , vol.26 , pp. 631-641
    • Tang, H.1    Guo, Q.2    Zhang, C.3    Zhu, J.4    Yang, H.5    Zou, Y.L.6    Yan, Y.7    Hong, D.8    Sou, T.9    Yan, X.M.10
  • 40
    • 77949907451 scopus 로고    scopus 로고
    • A ‘metastasis-prone’ signature for early-stage mismatch-repair proficient sporadic colorectal cancer patients and its implications for possible therapeutics
    • 20143136
    • Y.Hong, T.Downey, K.W.Eu, P.K.Koh, P.Y.Cheah. A ‘metastasis-prone’ signature for early-stage mismatch-repair proficient sporadic colorectal cancer patients and its implications for possible therapeutics. Clin Exp Metastasis 2010; 27:83-90; PMID:20143136; http://dx.doi.org/10.1007/s10585-010-9305-4
    • (2010) Clin Exp Metastasis , vol.27 , pp. 83-90
    • Hong, Y.1    Downey, T.2    Eu, K.W.3    Koh, P.K.4    Cheah, P.Y.5
  • 43
    • 84887156607 scopus 로고    scopus 로고
    • Parallel comparison of Illumina RNA-Seq and Affymetrix microarray platforms on transcriptomic profiles generated from 5-aza-deoxy-cytidine treated HT-29 colon cancer cells and simulated datasets
    • 23902433
    • X.Xu, Y.Zhang, J.Williams, E.Antoniou, W.R.McCombie, S.Wu, W.Zhu, N.O.Davidson, P.Denoya, E.Li. Parallel comparison of Illumina RNA-Seq and Affymetrix microarray platforms on transcriptomic profiles generated from 5-aza-deoxy-cytidine treated HT-29 colon cancer cells and simulated datasets. BMC Bioinformatics 2013; 14Suppl 9:S1; PMID:23902433; http://dx.doi.org/10.1186/1471-2105-14-S9-S1
    • (2013) BMC Bioinformatics , vol.14 , pp. 1
    • Xu, X.1    Zhang, Y.2    Williams, J.3    Antoniou, E.4    McCombie, W.R.5    Wu, S.6    Zhu, W.7    Davidson, N.O.8    Denoya, P.9    Li, E.10
  • 47
    • 84856040274 scopus 로고    scopus 로고
    • Analysis of molecular aberrations of Wnt pathway gladiators in colorectal cancer in the Kashmiri population
    • 21807601
    • A.Syed Sameer, Z.A.Shah, S.Abdullah, N.A.Chowdri, M.A.Siddiqi. Analysis of molecular aberrations of Wnt pathway gladiators in colorectal cancer in the Kashmiri population. Hum Genomics 2011; 5:441-52; PMID:21807601; http://dx.doi.org/10.1186/1479-7364-5-5-441
    • (2011) Hum Genomics , vol.5 , pp. 441-452
    • Syed Sameer, A.1    Shah, Z.A.2    Abdullah, S.3    Chowdri, N.A.4    Siddiqi, M.A.5
  • 48
    • 33750532320 scopus 로고    scopus 로고
    • Relationship between point gene mutation, chromosomal abnormality, and tumour suppressor gene methylation status in colorectal adenomas
    • 16902913
    • H.Judson, A.Stewart, A.Leslie, N.R.Pratt, D.U.Baty, R.J.Steele, F.A.Carey. Relationship between point gene mutation, chromosomal abnormality, and tumour suppressor gene methylation status in colorectal adenomas. J Pathol 2006; 210:344-50; PMID:16902913; http://dx.doi.org/10.1002/path.2044
    • (2006) J Pathol , vol.210 , pp. 344-350
    • Judson, H.1    Stewart, A.2    Leslie, A.3    Pratt, N.R.4    Baty, D.U.5    Steele, R.J.6    Carey, F.A.7
  • 49
    • 84863895600 scopus 로고    scopus 로고
    • Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity
    • 22745173
    • Z.Q.Wu, T.Brabletz, E.Fearon, A.L.Willis, C.Y.Hu, X.Y.Li, S.J.Weiss. Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity. Proc Natl Acad Sci USA 2012; 109:11312-7; PMID:22745173; http://dx.doi.org/10.1073/pnas.1203015109
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 11312-11317
    • Wu, Z.Q.1    Brabletz, T.2    Fearon, E.3    Willis, A.L.4    Hu, C.Y.5    Li, X.Y.6    Weiss, S.J.7
  • 50
    • 68849097853 scopus 로고    scopus 로고
    • Wnt/Planar cell polarity signaling: a new paradigm for cancer therapy
    • 19671746
    • Y.Wang. Wnt/Planar cell polarity signaling:a new paradigm for cancer therapy. Mol Cancer Ther 2009; 8:2103-9; PMID:19671746; http://dx.doi.org/10.1158/1535-7163.MCT-09-0282
    • (2009) Mol Cancer Ther , vol.8 , pp. 2103-2109
    • Wang, Y.1
  • 51
    • 84910066394 scopus 로고    scopus 로고
    • A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis
    • 25417160
    • T.S.Gujral, M.Chan, L.Peshkin, P.K.Sorger, M.W.Kirschner, G.MacBeath. A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis. Cell 2014; 159:844-56; PMID:25417160; http://dx.doi.org/10.1016/j.cell.2014.10.032
    • (2014) Cell , vol.159 , pp. 844-856
    • Gujral, T.S.1    Chan, M.2    Peshkin, L.3    Sorger, P.K.4    Kirschner, M.W.5    MacBeath, G.6
  • 52
    • 33749501476 scopus 로고    scopus 로고
    • Prickle-1 negatively regulates Wnt/beta-catenin pathway by promoting Dishevelled ubiquitination/degradation in liver cancer
    • 17030191
    • D.W.Chan, C.Y.Chan, J.W.Yam, Y.P.Ching, I.O.Ng. Prickle-1 negatively regulates Wnt/beta-catenin pathway by promoting Dishevelled ubiquitination/degradation in liver cancer. Gastroenterology 2006; 131:1218-27; PMID:17030191; http://dx.doi.org/10.1053/j.gastro.2006.07.020
    • (2006) Gastroenterology , vol.131 , pp. 1218-1227
    • Chan, D.W.1    Chan, C.Y.2    Yam, J.W.3    Ching, Y.P.4    Ng, I.O.5
  • 53
    • 84255173556 scopus 로고    scopus 로고
    • Wnt signaling and colon carcinogenesis: beyond APC
    • 21483657
    • R.Najdi, R.F.Holcombe, M.L.Waterman. Wnt signaling and colon carcinogenesis:beyond APC. J Carcinog 2011; 10:5; PMID:21483657; http://dx.doi.org/10.4103/1477-3163.78111
    • (2011) J Carcinog , vol.10 , pp. 5
    • Najdi, R.1    Holcombe, R.F.2    Waterman, M.L.3
  • 55
    • 0141606726 scopus 로고    scopus 로고
    • Effects of DNA methylation on expression of tumor suppressor genes and proto-oncogene in human colon cancer cell lines
    • 12970888
    • J.Y.Fang, J.Lu, Y.X.Chen, L.Yang. Effects of DNA methylation on expression of tumor suppressor genes and proto-oncogene in human colon cancer cell lines. World J Gastroenterol 2003; 9:1976-80; PMID:12970888; http://dx.doi.org/10.3748/wjg.v9.i9.1976
    • (2003) World J Gastroenterol , vol.9 , pp. 1976-1980
    • Fang, J.Y.1    Lu, J.2    Chen, Y.X.3    Yang, L.4
  • 56
    • 84866000382 scopus 로고    scopus 로고
    • PROX1 overexpression inhibits protein kinase C beta II transcription through promoter DNA methylation
    • 22833470
    • K.Hagiwara, H.Ito, T.Murate, Y.Miyata, H.Ohashi, H.Nagai. PROX1 overexpression inhibits protein kinase C beta II transcription through promoter DNA methylation. Genes Chromosomes Cancer 2012; 51:1024-36; PMID:22833470; http://dx.doi.org/10.1002/gcc.21985
    • (2012) Genes Chromosomes Cancer , vol.51 , pp. 1024-1036
    • Hagiwara, K.1    Ito, H.2    Murate, T.3    Miyata, Y.4    Ohashi, H.5    Nagai, H.6
  • 57
    • 0036613250 scopus 로고    scopus 로고
    • A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
    • 11992124
    • H.Suzuki, E.Gabrielson, W.Chen, R.Anbazhagan, M.van Engeland, M.P.Weijenberg, J.G.Herman, S.B.Baylin. A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nat Genet 2002; 31:141-9; PMID:11992124; http://dx.doi.org/10.1038/ng892
    • (2002) Nat Genet , vol.31 , pp. 141-149
    • Suzuki, H.1    Gabrielson, E.2    Chen, W.3    Anbazhagan, R.4    van Engeland, M.5    Weijenberg, M.P.6    Herman, J.G.7    Baylin, S.B.8
  • 59
    • 84929628130 scopus 로고    scopus 로고
    • Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation
    • 25074712
    • S.Lou, H.M.Lee, H.Qin, J.W.Li, Z.Gao, X.Liu, L.L.Chan, V.Kl Lam, W.Y.So, Y.Wang, et al. Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation. Genome Biol 2014; 15:408; PMID:25074712; http://dx.doi.org/10.1186/s13059-014-0408-0
    • (2014) Genome Biol , vol.15 , pp. 408
    • Lou, S.1    Lee, H.M.2    Qin, H.3    Li, J.W.4    Gao, Z.5    Liu, X.6    Chan, L.L.7    Kl Lam, V.8    So, W.Y.9    Wang, Y.10
  • 60
  • 61
  • 62
    • 84859210032 scopus 로고    scopus 로고
    • Fast gapped-read alignment with Bowtie 2
    • 22388286
    • B.Langmead, S.L.Salzberg. Fast gapped-read alignment with Bowtie 2. Nat Methods 2012; 9:357-9; PMID:22388286; http://dx.doi.org/10.1038/nmeth.1923
    • (2012) Nat Methods , vol.9 , pp. 357-359
    • Langmead, B.1    Salzberg, S.L.2
  • 63
    • 84980022597 scopus 로고    scopus 로고
    • National Center for Biotechnology Information. http://www.ncbi.nlm.nih.gov/assembly/GCF_000001405.13/
  • 64
    • 68549104404 scopus 로고    scopus 로고
    • 1000 Genome Project Data Processing Subgroup. The Sequence Alignment/Map format and SAMtools
    • 19505943
    • H.Li, B.Handsaker, A.Wysoker, T.Fennell, J.Ruan, N.Homer, G.Marth, G.Abecasis, R.Durbin. 1000 Genome Project Data Processing Subgroup. The Sequence Alignment/Map format and SAMtools. Bioinformatics 2009; 25:2078-9; PMID:19505943; http:dx.doi.org/10.1093/bioinformatics/btp352
    • (2009) Bioinformatics , vol.25 , pp. 2078-2079
    • Li, H.1    Handsaker, B.2    Wysoker, A.3    Fennell, T.4    Ruan, J.5    Homer, N.6    Marth, G.7    Abecasis, G.8    Durbin, R.9


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